Main >> Izidakamizwa Vs. Umngani >> I-Methylprednisolone vs. prednisone: Umehluko, ukufana, nokuthi yikuphi okungcono

I-Methylprednisolone vs. prednisone: Umehluko, ukufana, nokuthi yikuphi okungcono

Izidakamizwa Vs. Umngani

I-Methylprednisolone ne-prednisone ngama-synthetic glucocorticoids asetshenziswa ezinkingeni ezahlukahlukene. Le mithi ifana kakhulu namahomoni akhiqizwa i-adrenal gland yomzimba wakho. Lapho inikezwa ngemithamo ephezulu kunaleyo umzimba wakho obeyovame ukuzenzela yona, isebenza ezindleleni ezahlukahlukene ukuvimbela izimpawu ezithile zokuzivikela nokuvuvukala ezinjenge-leukotrienes, i-prostaglandins, i-kinins, ne-histamines. Le ndlela yokusebenza ivumela le mithi ukuthi isebenze ekwelapheni izifo zokuphefumula, ukuphazamiseka komzimba, nokuphazamiseka kokuvuvukala, ukusho okumbalwa. Ngenkathi yomibili le mithi ingasetshenziswa ezinkingeni ezifanayo, kukhona umehluko phakathi kwalokhu okubili.

Uyini umehluko omkhulu phakathi kwe-methylprednisolone ne-prednisone?

IMethylprednisolone ngumuthi kadokotela osetshenziswa ezinkingeni ezahlukahlukene kubandakanya i-asthma, i-ulcerative colitis, i-rheumatoid arthritis, kanye ne-allergic reaction. IMethylprednisolone yinto esuselwe ku-prednisolone, futhi indlela esebenza ngayo iyenza ibe wusizo ezinhlobonhlobo zokuphazamiseka kokuvuvukala nokuzivikela komzimba. IMethylprednisolone yeqa ulwelwesi lweselula futhi ibophezela kuma-receptors avimbela amaprotheni synthesis kanye nokukhiqizwa kwama-cytokines. Ama-cytokines adlala indima ebalulekile kunqubo yokuvuvukala. Ngalo mshini ofanayo, futhi kumisa nokungena kwama-leukotrienes namanye amamaki okuphendula komzimba. Lokhu kwenza ukuthi lesi sidakamizwa sisebenze njenge-anti-inflammatory ne-immunosuppressive agent.

IMethylprednisolone itholakala ku-4 mg, 8 mg, 16 mg, naku-32 mg amaphilisi omlomo. Futhi iyatholakala ezixazululweni ezinganikezwa njengemijovo efakwa emithanjeni noma emithanjeni. Igama lomkhiqizo lamaphilisi e-methylprednisolone yi-Medrol. IMethylprednisolone ingasetshenziswa ezinganeni, ezinganeni nakubantu abadala.

I-Prednisone umuthi kadokotela obuye usetshenziswe ezinhlobonhlobo zezifo zokuvuvukala kanye nezokuzivikela komzimba. I-Prednisone isuselwa ku-cortisone futhi kufanele ihlanganiswe nesibindi sibe yimo esebenzayo, i-prednisolone, ukuze iwele ulwelwesi lweselula. Lapho isinqamula ulwelwesi, indlela esebenza ngayo iyefana naleyo ye-methylprednisolone ngoba ivimbela ukungena kwezimpawu zokuvuvukala nezokuzivikela komzimba.

IPrednisone nayo ingabizwa ngegama layo lomkhiqizo iDeltasone. Itholakala ku-2.5 mg, 5 mg, 10 mg, 20 mg, naku-50 mg amaphilisi omlomo. Iphinde itholakale kwisisombululo somlomo.

Umehluko omkhulu phakathi kwe-methylprednisolone vs. prednisone
	I-Methylprednisolone	Prednisone
Isigaba sezidakamizwa	ICorticosteroid	ICorticosteroid
Isimo somkhiqizo / ejwayelekile	I-Brand ne-generic iyatholakala	I-Brand ne-generic iyatholakala
Ngubani igama lomkhiqizo?	IMedrol, iSoluMedrol	Deltasone
Izidakamizwa zingena ngaziphi izinhlobo?	Ithebhulethi yomlomo, Isixazululo somjovo	Ithebhulethi yomlomo, isisombululo somlomo
Uyini umthamo ojwayelekile?	Umthamo wokuqala we-4 mg kuya ku-48 mg nge-titration ngokususelwa ekuphenduleni nasekuxilongweni	Umthamo wokuqala we-5 mg kuya ku-60 mg nge-titration ngokususelwa ekuphenduleni nasekuxilongweni
Yelashwa isikhathi esingakanani?	Izinsuku eziyisithupha kuze kube amasonto amaningana noma ngaphezulu kuye ngokuxilongwa.	Izinsuku ezinhlanu kuze kube amasonto amaningana noma ngaphezulu kuye ngokutholakala kwesifo.
Ubani ovame ukusebenzisa umuthi?	Izinsana, izingane, nabantu abadala	Izinsana, izingane, nabantu abadala

Ufuna intengo engcono kakhulu ku-prednisone?

Bhalisela izexwayiso zentengo ye-prednisone bese uthola ukuthi intengo ishintsha nini!

Thola izexwayiso zentengo

Izimo eziphathwa yi-methylprednisolone vs. prednisone

IMethylprednisolone isetshenziswa ekwelapheni izifo nezifo ezahlukahlukene. Umphumela wayo enqubeni yokuvuvukala uyenza ibe lusizo ezinkingeni zamathambo ezifana ne-rheumatoid ne-psoriatic arthritis, i-spondylitis, ne-bursitis. Ibuye isetshenziselwe ukwelapha ukuqhuma okukhulu kwesifuba somoya. Izici zokuzivikela zomzimba ze-methylprednisolone zikwenza kube ukwelashwa okusebenzayo ezimeni ezingezwani ne-rhinitis, i-contact dermatitis, kanye nokuzwela kwezidakamizwa. Ibuye isetshenziswe ku-endocrine, collagen, hematologic, emathunjini nasezifo zamehlo.

I-Prednisone ibuye isetshenziselwe ukwelashwa okunhlobonhlobo kokuphazamiseka kokuvuvukala nokuzimela komzimba okufana ne-methylprednisolone. Lokhu kufaka phakathi i-rheumatic, respiratory, allergic, endocrine, collagen, hematologic, emathunjini kanye nokuphazamiseka kwamehlo.

Ithebula elilandelayo, ngenkathi libanzi, kungenzeka lingabhali konke ukusetshenziswa kwale mithi emibili. Sicela uxhumane nomhlinzeki wakho wezokunakekelwa kwempilo ukuthola eminye imininingwane ngezinkomba zokusebenzisa.

Isimo	I-Methylprednisolone	Prednisone
I-hyperplasia yokuzalwa ye-adrenal	Yebo	Yebo
I-thyroiditis engasebenzi	Yebo	Yebo
Isifo samathambo	Yebo	Yebo
I-Ankylosing spondylitis	Yebo	Yebo
I-bursitis enamandla	Yebo	Yebo
I-synovitis ye-osteoarthritis	Yebo	Yebo
I-psoriatic arthritis	Yebo	Yebo
Uhlelo lupus erythematosus	Yebo	Yebo
I-seborrheic dermatitis enamandla	Yebo	Yebo
I-psoriasis enamandla	Yebo	Yebo
I-optic neuritis	Yebo	Yebo
I-conjunctivitis yokungezwani komzimba	Yebo	Yebo
I-sarcoidosis yezimpawu	Yebo	Yebo
Ukuphefumula i-pneumonitis	Yebo	Yebo
Idiopathic thrombocytopenic purpura	Yebo	Yebo
I-ulcerative colitis	Yebo	Yebo
Ukukhula okunamandla kwe-Multiple Sclerosis	Yebo	Yebo

Ingabe i-methylprednisolone noma i-prednisone isebenza kangcono?

Kunezindlela eziningi zokuqhathanisa i-methylprednisolone ne-prednisone ngenxa yokusebenzisa kwazo okuhlukahlukene. Kuzinqubo eziningi zokuvuvukala, ukwelashwa ngama-corticosteroids kukhawulelwe ekusetshenzisweni kwesikhashana esifushane ekukhuphukeni okukhulu nokubi kwesifo. Uma uqhathanisa i-methylprednisolone ne-prednisone ngqo, i-4 mg ye-methylprednisolone ilingana no-5 mg we-prednisone. Kodwa-ke, lapho amanani alungiswa futhi ehlolwe ukuphendula, ngalinye lingasebenza ekwelashweni.

Ucwaningo oluthile lwazama ukuqhathanisa i- imiphumela ye-methylprednisolone emithanjeni ku-prednisone yomlomo ekukhuleni okukhulu kwe-asthma ezinganeni. Amaqembu amabili okwelashwa ahlelwe ngokungahleliwe ukuthola i-30 mg ye-methylprednisolone efakwa emthanjeni noma i-30 mg ye-oral prednisone. Womabili la maqembu athola i-albuterol, futhi abacwaningi bahlola ukukhululeka kwezimpawu, ukugeleza okuphezulu kokuphefumula (PEF), kanye nokufundwa kwe-oximetry. Ukufundwa kuthathwe eqenjini ngalinye emahoreni amabili, amane, nakayisithupha ngemuva kokuqala ukwelashwa. Kwakungekho mehluko obalulekile emtholampilo noma ngokwezibalo esikhaleni ngasinye phakathi kwamaqembu amabili. Abaphenyi baphetha ngokuthi i-prednisone yomlomo kungaba ukukhetha okungcono kakhulu ngenxa yezindleko eziphansi kanye nokuphathwa okuhlukumezayo kancane.

Ufuna intengo engcono kakhulu ku-methylprednisolone?

Bhalisela izexwayiso zentengo ye-methylprednisolone bese uthola ukuthi intengo ishintsha nini!

Thola izexwayiso zentengo

Ukuhlanganiswa nokuqhathaniswa kwezindleko kwe-methylprednisolone vs. prednisone

IMethylprednisolone ngumuthi kadokotela ovame ukumbozwa yizinhlelo zombili zomshuwalense wezohwebo kanye neMedicare. Inkambo yezinsuku eziyisithupha yamathebulethi angama-21 amandla we-4 mg ingabiza imali engango- $ 100 ngegama lomkhiqizo. Ngesigqebhezana esivela kwaSingleCare, ungathola i-methylprednisolone ngemali ephansi njengo- $ 15.

I-Prednisone nayo iyimithi kadokotela evame ukuhlanganiswa yizinhlelo zombili zomshuwalense wezohwebo kanye neMedicare. Intengo emaphakathi yokuthengisa ye-prednisone icishe ibe ngama- $ 22 ngamathebulethi ayishumi angama-20 mg. Ungahle ukwazi ukuthola lo muthi ngemali engaphansi kuka- $ 4 ngesigqebhezana se-SingleCare.

Kubalulekile ukuqaphela ukuthi ezifundeni ezithile zezifo, ama-corticosteroids kungenzeka angambozwa ngaphansi kwenzuzo yezidakamizwa, kepha angambozwa ngaphansi kwe-Medicare Part B. Usokhemisi wakho anganikeza imininingwane ethe xaxa ngokutholakala.

	I-Methylprednisolone	Prednisone
Ngokuvamile embozwe umshwalense?	Yebo	Yebo
Imbozwe ngokujwayelekile yi-Medicare?	Yebo	Yebo
Umthamo ojwayelekile	21, 4 mg amaphilisi	10, 20 mg amaphilisi
I-Medicare copay ejwayelekile	Ngokuvamile<$10 but may vary depending on the plan	Ngokuvamile<$10 but may vary depending on the plan
Izindleko ze-SingleCare	$ 15 +	$ 4- $ 6

Imiphumela emibi ejwayelekile ye-methylprednisolone ne-prednisone

I-Prednisone ihlanganiswa ne-prednisolone yayo esebenzayo ngesibindi. I-Prednisolone ne-methylprednisolone zifana ngokwamakhemikhali, ngakho-ke imiphumela yazo emibi engaba khona iyasondelana.

Ama-Glucocorticoids ayaziwa ukuthi abangela ukungalingani oketshezi kanye ne-electrolyte okungaholela ekugcineni i-sodium noketshezi, umfutho wegazi ophakeme, futhi kwezinye izimo, ukwehluleka kwenhliziyo okucinana. I-Methylprednisolone ne-prednisone nazo zingaholela ekubeni buthakathaka kwemisipha kanye nokulahleka kwesisindo semisipha. Ama-Glucocorticoids aziwa njengokuphazamisa uhlelo lwesisu futhi angaholela ekucanuzelweni yinhliziyo, ukuhlanza noma ukuqunjelwa esiswini. I-Steroids inganciphisa ukwelashwa kwamanxeba. Ukusetshenziswa isikhathi eside kwe-methylprednisolone ne-prednisone kunganciphisa ukukhula kwezingane, futhi ngenxa yalesi sizathu, ukusetshenziswa kwazo kufanele kukhawulelwe esikhathini esifushane ngangokunokwenzeka ukufeza ukuxolelwa kwezimpawu.

I-Glucocorticoids ingaphazamisa impendulo yomzimba ku-insulin. Iziguli ezelashwa isikhathi eside ze-steroid zingaba namathuba aphindwe kane okuba nesifo sikashukela. Iziguli ezincike ku-insulin ejojowe noma ezinye izidakamizwa ezilwa nesifo sikashukela kungadingeka zikhuphule umthamo wazo ngenkathi ziku-steroids. Kuvamile ukuthi abantu abanesifo sikashukela abalawulwa kahle babone ukwanda koshukela wegazi labo noma ngasesilinganisweni esifushane kakhulu se-steroids.

Ithebula elilandelayo alihloselwe ukuthi libe uhlu olubanzi lwemiphumela emibi. Sicela uxhumane nosokhemisi noma udokotela wakho ukuthola uhlu oluphelele lwayo yonke imiphumela emibi.

	I-Methylprednisolone	Prednisone
Ukugcinwa kwesodium	Kusebenza?	Imvamisa	Kusebenza?	Imvamisa
Ukugcinwa kwamanzi	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Umfutho wegazi ophezulu	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Ukwehluleka kwenhliziyo yokubopha	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Ukuzuza kwesisindo	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Ubuthakathaka bemisipha	Yebo	Akuchaziwe	Yebo	Akuchaziwe
I-osteoporosis	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Ukwephuka kwamathambo amade	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Isilonda se-Peptic	Yebo	Akuchaziwe	Yebo	Akuchaziwe
I-Pancreatitis	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Ukuhlukaniswa kwesisu	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Ukupholisa ukulimala kwesilonda	Yebo	Akuchaziwe	Yebo	Akuchaziwe
I-erythema ebusweni	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Ukujuluka okwengeziwe	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Ubuhlungu bekhanda	Yebo	Akuchaziwe	Yebo	Akuchaziwe
I-Vertigo	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Ukushintsha kwemizwelo	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Ukucindezelwa kokukhula	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Ukumelana ne-insulin	Yebo	Akuchaziwe	Yebo	Akuchaziwe
I-Glaucoma	Yebo	Akuchaziwe	Yebo	Akuchaziwe

Umthombo: I-Methylprednisolone (I-DailyMed) Prednisone (I-DailyMed)

Ukusebenzisana kwezidakamizwa kwe-methylprednisolone ne-prednisone

I-Methylprednisolone ne-prednisone yizindawo ezingaphansi kwe-cytochrome P450 enzyme 3A4. Uhlelo lwe-P450 enzyme esibindini lubhekele ukwakheka kwemithi eminingi, ngakhoke kunamathuba amaningi okuhlangana kwezidakamizwa.

Ama-Corticosteroids asetshenziswa kakhulu ezigulini ezikwamanye ama-immunosuppressant agents. Ukulawula impendulo yomzimba ekufakweni komzimba kanye nokuphazamiseka okuthile okuzenzakalelayo kungadinga ukusetshenziswa kwe-ejenti engaphezu kweyodwa ye-immunosuppressive agent. I-ejenti eyodwa ingathinta imetabolism yomunye, kepha isengasetshenziswa ndawonye uma ihlolwe ngokufanele. Isibonelo, i-tacrolimus ne-cyclosporine yi-inhibitors ngayinye ye-CYP 3A4. Lokhu kungaholela ekukhuleni kwe-serum okwandayo kwe-methylprednisolone noma i-prednisone lapho isetshenziswa ndawonye. Kube khona izehlakalo zokudlikizela okubikwe ngokusetshenziswa ngasikhathi sinye kwe-cyclosporine ne-methylprednisolone, yize lokhu kungavamile.

I-Loop diuretics isiza ukuphatha isimo soketshezi emzimbeni ngokuhlunga i-potassium. Uma unikezwa nge-methylprednisolone noma i-prednisone, noma kunjalo, kukhona amandla okuthi umzimba ulahlekelwe yi-potassium eningi. Lokhu kungaba nemiphumela emibi ekusebenzeni kwenhliziyo. Iziguli okufanele zikuthathe ndawonye kufanele zibhekelwe isimo sazo se-electrolyte.

Ithebula elilandelayo alulona uhlu lwayo yonke imiphumela emibi engaba khona. Sicela uthinte umhlinzeki wakho wezokunakekelwa kwempilo ukuthola uhlu oluphelele.

Izidakamizwa	Isigaba Sezidakamizwa	I-Methylprednisolone	Prednisone
I-Baricitinib Dabrafenib Erdafitinib Ivosidenib Larotrectinib Tofacitinib Upadacitinib	I-Signal transduction inhibitors (i-STI): Ama-Immunosuppressants	Yebo	Yebo
I-Denosumab UNatalizumab UNivolumab Ocrelizumab USarilumab I-Siltuximab	Ama-Immunoglobulins: Ama-Immunosuppressants	Yebo	Yebo
Tacrolimus	I-Calcineurin inhibitor: I-Immunosuppressant	Yebo	Yebo
ICyclosporine	I-peptide ejikelezayo: I-Immunosuppressant	Yebo	Yebo
I-Aprepitant I-Fosaprepitant	Umphikisi we-NK1 receptor: Anti-nausea	Yebo	Yebo
Ketoconazole I-Itraconazole	Ama-antifungal we-Azole	Yebo	Yebo
Unyazi	IVasopressin analog	Yebo	Yebo
Diltiazem	Isivimbeli sesiteshi seCalcium	Yebo	Yebo
Isoniazid I-Rifampin	I-Antitubercular	Yebo	Yebo
Phenytoin	I-Anticonvulsant	Yebo	Yebo
I-Bumetanide UFurosemide I-Torsemide	I-Loop Diuretics	Yebo	Yebo
I-Aspirin Ibuprofen I-Naproxen I-Diclofenac UMeloxicam UCelecoxib	Ama-NSAID	Yebo	Yebo
I-Chlorthalidone I-Hydrochlorothiazide	I-Thiazide isisu	Yebo	Yebo

Izexwayiso ze-methylprednisolone ne-prednisone

Ama-Corticosteroids angafihla izimpawu zokutheleleka futhi anganciphisa ukutholakala kwezifo ezintsha. Ukusetshenziswa isikhathi eside kwe-methylprednisolone ne-prednisone kungaholela ku-cataract nase-glaucoma.

Azikho izifundo ezilawulwa kahle ze-corticosteroids kwabesifazane abakhulelwe, ngakho-ke ukusetshenziswa kwabo ekukhulelweni kufanele kwenzeke kuphela lapho kusobala ukuthi inzuzo idlula noma iziphi izingozi. Izinsana ezizalwe ngomama abasebenzisa i-corticosteroids ngesikhathi sokukhulelwa kufanele zibhekwe nge-hypoadrenalism.

I-Corticosteroids, ikakhulukazi ngemithamo ephezulu, izovimbela amandla omzimba wokukhiqiza amasosha omzimba lapho kunikezwa imigomo. Imithi yokugoma kungenzeka ingasebenzi ezigulini ezithola ama-steroids. Imishanguzo ebukhoma, efana nengxibongo, akufanele inikezwe iziguli ezithola ukwelashwa kwe-corticosteroid. Iziguli ezithatha ama-immunosuppressive agents zisengozini enkulu yokutheleleka emithini yokugoma ebukhoma.

IMethylprednisolone ne-prednisone kungashintsha imiphumela yokuhlolwa kwesikhumba noma okunye ukuhlolwa kokungezwani komzimba. Ukuze uthole imiphumela enembile kunazo zonke, ukwelashwa kwe-steroid kufanele kumiswe ezinsukwini ngaphambi kokwenza lezi zivivinyo.

Ama-steroid kufanele anikezwe kuphela isikhathi esifushane ngangokunokwenzeka ukufeza imiphumela oyifunayo. Uma ukusetshenziswa kwesikhathi eside kwe-steroids kuyadingeka kwezokwelapha, kufanele kugcinwe kumthamo ophansi kakhulu osebenzayo.

Imibuzo ebuzwa njalo mayelana ne-methylprednisolone vs. prednisone

Yini i-methylprednisolone?

IMethylprednisolone iyi-synthetic glucocorticoid esetshenziselwa ukwelapha ukungezwani okuhlukahlukene kokuvuvukala nokuzimela. Itholakala njengethebhulethi yomlomo nanjengomjovo. Isikhathi eselashwa kakhulu kunazo zonke izinsuku eziyisithupha zokwelashwa ngomlomo.

Yini i-prednisone?

I-Prednisone iyi-glucocorticoid ehlanganiswa nesibindi ifomu layo elisebenzayo, i-prednisolone. Ibuye isetshenziswe ezifweni eziningi zokuvuvukala nezizimele. I-Prednisone iyatholakala kumathebulethi womlomo nangendlela yokwenziwa kwezixazululo zomlomo. Ukusetshenziswa okuhle kwe-prednisone imvamisa kuyindlela yezinsuku ezinhlanu.

Ngabe i-methylprednisolone ne-prednisone ziyefana?

Yize zombili zingama-glucocorticoids, i-methylprednisolone ne-prednisone azifani ncamashi. I-Prednisone kufanele ihlanganiswe ngendlela yayo esebenzayo, i-prednisolone, ukuze ibe nomthelela emzimbeni. Umthamo we-4 mg we-methylprednisolone ulingana ne-5 mg prednisone.

Ngabe i-methylprednisolone noma i-prednisone ingcono?

IMethylprednisolone ne-prednisone ngamunye angafeza ukuxolelwa kwezimpawu lapho amanani abo eqalwa ngokufanele. Ukwakhiwa komlomo kungancanyelwa kunokwakhiwa komjovo ngenxa yezindleko eziphansi kanye nokuphathwa kalula.

Ngingayisebenzisa i-methylprednisolone noma i-prednisone ngenkathi ngikhulelwe?

IMethylprednisolone ne-prednisone yizigaba zobungozi bokukhulelwa C. Lokhu kusho ukuthi azikho izifundo zabantu ezilawulwayo ezifakazela ukuthi umuthi uphephile ekukhulelweni. Le mithi kufanele isetshenziswe kuphela lapho inzuzo ivelela ubungozi.

Ngingayisebenzisa yini i-methylprednisolone noma i-prednisone ngotshwala?

Utshwala buhlanganiswa nesibindi. Ukuphuza okuqhubekayo kotshwala kungathinta amandla omzimba wokusebenzisa i-prednisone esimeni sayo esisebenzayo. Utshwala kanye ne-glucocorticoids bobabili kungaba nemiphumela emibi ohlelweni lwamathumbu. Ukusetshenziswa kotshwala kuncishiswe kakhulu ngesikhathi sokwelashwa kwe-steroid.

Ingabe i-methylprednisolone iyi-steroid enamandla?

Ngenkathi i-methylprednisolone icishe ibe namandla angaphezulu ngama-20% kune-prednisone, ingamandla ayisihlanu kuphela amandla amanye ama-glucocorticoids afana ne-dexamethasone noma i-betamethasone. Noma kunjalo, inamandla aphindwe kahlanu kune-hydrocortisone.

Kuthatha isikhathi esingakanani ukuthi i-methylprednisolone iqale ukusebenza? / Ingabe i-methylprednisolone isebenza ngokushesha?

IMethylprednisolone inokuqala okusheshayo. Ifinyelela umphumela wayo omkhulu kungakapheli ihora elilodwa kuya kwamabili ngemuva komthamo womlomo, futhi kungakapheli ihora elilodwa lomthamo wemithambo. Ihlanganiswa nesibindi ibe yimetabolite engasebenzi ekhishwa emchameni. Isikhathi sempilo se-methylprednisolone ngamahora angama-18 kuya kwangama-36 okusho ukuthi kungathatha izinsuku ezi-2 kuye kwezi-7 ukuqeda ngokuphelele umuthi emzimbeni.