Main >> Izidakamizwa Vs. Umngani >> I-Xyzal vs. Allegra: Umehluko, ukufana, nokuthi yikuphi okungcono kuwe

I-Xyzal vs. Allegra: Umehluko, ukufana, nokuthi yikuphi okungcono kuwe

Izidakamizwa Vs. Umngani

I-Xyzal (levocetirizine) ne-Allegra (fexofenadine) ngama-antihistamine wesizukulwane sesibili ngasinye. Ama-antihistamine aphikisana ne-H1 receptor etholakala ngokuyinhloko ezicubu zomzimba ezibushelelezi, amaseli endothelial vascular, inhliziyo, kanye nohlelo oluphakathi lwezinzwa. Ngenkathi bengakuyeki ukukhiqizwa kwe-histamine, bancintisana nayo kusiza se-H1 receptor ukunciphisa noma ukuvimba imiphumela ye-histaminic. I-Histamine ibhekene nezimpawu zokungezwani komzimba njengokuthimula, i-rhinitis (ikhala eligijimayo), amehlo alumayo, ukuminyana kwamakhala nokuvuvukala, ukulunywa kwesikhumba kanye ne-edema.

Ama-antihistamine esizukulwane sokuqala, afaka i-diphenhydramine ne-chlorpheniramine, ayesebenza kakhulu ekuvimbeleni ama-histamine receptors kepha ayenza okufushane futhi ehlezi. Ama-antihistamine wesizukulwane sesibili athuthukiswa ukuze asebenze isikhathi eside futhi ahlalise kancane ukuthuthukisa ikhwalithi yempilo yesineke.

Ama-antihistamine wesizukulwane sesibili, ngenxa yomsebenzi wawo endaweni yokwamukela i-H1, ayasebenziseka ekwelapheni izimo ezifana ne-allergen rhinitis ngenxa yokungezwani komzimba ngezikhathi ezithile zonyaka noma ezithile, ukungezwani komzimba nesikhumba okungahambi kahle, kanye ne-idiopathic urticaria engapheli. Amanye ama-antihistamine wesizukulwane sesibili afaka uClaritin (loratadine), uClarinex (desloratadine), noZyrtec (cetirizine).

Uyini umehluko omkhulu phakathi kweXyzal ne-Allegra?

I-Xyzal iyi-antihistamine yesizukulwane sesibili etholakala kokubili njengemithi kadokotela kanye nemithi ethengiswayo. Uhlobo lwezidakamizwa ezijwayelekile, i-levocetirizine, luyatholakala kokubili njengemithi kadokotela kanye ne-counter-the-counter. I-Xyzal ibhekwa njenge-antihistamine ephansi, okusho ukuthi ingadala ukozela, kepha akulindelekile ukuthi iphazamise ukusebenza kwezimoto noma amandla engqondo. Njengomuthi kadokotela, i-Xyzal noma i-generic yayo ingambozwa yi-Medicare noma umshuwalense wezohwebo, noma kungahle kube nokuhlukile ngoba kutholakala ngaphezu kwe-counter. I-Xyzal iyatholakala njengethebhulethi yomlomo engu-5 mg noma isisombululo somlomo esingu-2.5 mg / ml. Isixazululo se-Xyzal esithenga ngaphezulu singasetshenziswa ezinganeni ezineminyaka emibili noma ngaphezulu. Njengomuthi kadokotela, udokotela wakho anganikeza uXyzal ingane enezinyanga eziyisithupha ubudala.

I-Allegra futhi iyi-antihistamine yesizukulwane sesibili etholakala kokubili njengemithi kadokotela kanye ne-counter-the-counter. Uhlobo lwezidakamizwa ezijwayelekile, i-fexofenadine, luyatholakala futhi njengombhalo kadokotela nangaphezulu kwe-counter. I-Allegra ihlukaniswa njenge-antihistamine engahlali phansi, okusho ukuthi ukozela akuyona imiphumela emibi elindelekile ekuthatheni lo muthi. Njengomuthi kadokotela, i-Allegra noma i-generic yayo ingambozwa yiMedicare noma umshuwalense wezentengiso, yize kaningi kungengenxa yokuthi itholakala ngaphezu kwekhawunta. I-Allegra iyatholakala njengethebhulethi yomlomo ngamandla we-30 mg, 60 mg, no-180 mg. Ibuye itholakale njengesisombululo ekugxileni kwe-30 mg / 5 ml. Ezinganeni, kukhona ne-30 mg tablet engancibilika. Ukumiswa kuka-Allegra okungaphezulu kwekhawunda kungasetshenziswa ezinganeni ezineminyaka emibili noma ngaphezulu. Njengomuthi kadokotela, udokotela wakho anganquma ukumiswa kwe-Allegra enganeni enezinyanga eziyisithupha ubudala.

Umehluko omkhulu phakathi kweXyzal ne-Allegra
	Xyzal	I-Allegra
Isigaba sezidakamizwa	I-antihistamine yesizukulwane sesibili	I-antihistamine yesizukulwane sesibili
Isimo somkhiqizo / ejwayelekile	I-Brand ne-generic iyatholakala	I-Brand ne-generic iyatholakala
Ngubani igama elijwayelekile?	I-Levocetirizine	I-Fexofenadine
Izidakamizwa zingena ngaziphi izinhlobo?	Ithebhulethi yomlomo nesisombululo somlomo	Ithebhulethi yomlomo, ukumiswa ngomlomo, ithebhulethi engaqedwa
Uyini umthamo ojwayelekile?	Ithebhulethi engu-5 mg kanye ngosuku	Ithebhulethi engu-180 mg kanye ngosuku
Yelashwa isikhathi esingakanani?	Izinsuku eziyi-10 kuya kwezingu-14 noma ngaphezulu ngokuya ngenkomba nobukhona be-allergen	Izinsuku eziyi-10 kuya kwezingu-14 noma ngaphezulu ngokuya ngenkomba nobukhona be-allergen
Ubani ovame ukusebenzisa umuthi?	Izingane ezineminyaka engu-6 ubudala noma ngaphezulu, abantu abadala	Izingane ezineminyaka engu-6 ubudala noma ngaphezulu, abantu abadala

Izimo eziphathwa yi-Xyzal ne-Allegra

I-Xyzal (Iyini i-Xyzal?) Ikhonjiswa kubantu abadala ukuthi belaphe i-allergen rhinitis ngenxa yokungezwani komzimba okungapheli noma okwenzeka ngezikhathi ezithile zonyaka, ukungezwani komzimba nesikhumba okungahambi kahle, kanye ne-urticaria engapheli yesifo. Ezinganeni, odokotela bangahle banikeze u-Xyzal ezinganeni ezineminyaka esukela kwezingu-6 ubudala ukuthola i-urticaria engapheli. Uma kungenjalo, izingane ezineminyaka emibili noma ngaphezulu zingasebenzisa i-Xyzal ngaphezu kwe-counter for rhinitis yokugula noma i-idiopathic urticaria engapheli.

I-allergen rhinitis ibonakala ngezimpawu ezifana nekhala eligijimayo, isiminyaminya samakhala, ukulunywa kanye / noma amehlo anamanzi, ukuthimula, nokucasula isikhumba noma ukulunywa. Ukungezwani komzimba nesikhumba kungabonakala njengezindawo ezibomvu eziphakanyisiwe noma ezivuvukile zesikhumba (isifuba), ukuqubuka, ukuvuvukala nokunwaya.

I-Allegra (Yini i-Allegra?) Ikhonjiswa kubantu abadala ukuthi belaphe i-allergen rhinitis ngenxa yokungezwani komzimba okungapheli noma okwenzeka ngezikhathi ezithile zonyaka, ukungezwani komzimba nesikhumba okungahambi kahle, kanye ne-urticaria engapheli yesifo. Ezinganeni, odokotela bangahle banikeze i-Allegra ezinganeni ezineminyaka engaphansi kwezinyanga eziyisithupha ubudala ukuthola i-urticaria engapheli. Ngaphandle kwalokho, izingane ezineminyaka emibili noma ngaphezulu zingasebenzisa i-Allegra ngaphezu kwe-counter for rhinitis yokugula noma i-idiopathic urticaria engapheli.

Isimo	Xyzal	I-Allegra
I-rhinitis yokungezwani	Yebo	Yebo
Ukungezwani kwesikhumba	Yebo	Yebo
I-urticaria engapheli ye-idiopathic	Yebo	Yebo

Ngabe iXyzal noma i-Allegra isebenza ngempumelelo kakhulu?

U-Xyzal no-Allegra baqhathaniswe ngqo nokuhlola ukuthuthuka kwezimpawu zabo ezigulini ezine-allergen rhinitis ezazivezwe impova ekhubekisayo. Eyodwa funda wabeka iziguli eVienna Challenge Chamber amahora amane enempova yotshani, namahora amabili esifundweni, ukwelashwa kwaqalwa nge-placebo, 5 mg levocetirizine, noma i-120 mg ye-fexofenadine. Ngemuva kwamahora angamashumi amabili nambili ngemuva kokuphathwa kwezidakamizwa, iziguli zaphinde zathola impova amahora engeziwe ayisithupha. Abaphenyi balinganisa inani eliphelele lezimpawu zamakhala ezigijimayo, ukuthimula, ikhala elilumayo namehlo. Ngamahora amabili ngemuva kokuphathwa, zombili i-levocetirizine ne-fexofenadine zazingcono kakhulu kune-placebo, kodwa zangahlukile kakhulu komunye nomunye. Kodwa-ke, emahoreni angama-22-24 ngemuva kokuphathwa, iqembu levocetirizine lithole umehluko omkhulu emtholampilo ekuthuthukiseni izimpawu. Lokhu kwagcinwa kwaze kwaba sezingeni lamahora angama-28 ngemuva kokuphathwa. Ngenkathi zombili lezi zidakamizwa zazisebenza ekukhululekeni kwezimpawu ekuqaleni, i-levocetirizine yayinesikhathi eside sisebenza futhi igcina ukukhululeka kwezimpawu isikhathi eside.

I-allergen yakho inganquma ukuthi imiphi imithi yokungezwani komzimba ekufanele kakhulu.

Ukuqhathaniswa kanye nezindleko ze-Xyzal vs. Allegra

I-Xyzal ingambozwa yi-Medicare noma izinhlelo zokuhweba, noma ngabe izinga lokumboza lingahluka ngoba litholakala ngaphezu kwe-counter. Kaningi kunalokho, izinhlelo zeMedicare azizibandakanyi izidakamizwa ezitholakala ngaphezu kwekhawunta. Izindleko ze-generic Xyzal njengedokotela zingaba ngaphezu kwama- $ 100 kwamanye amakhemisi. Ngesigqebhezana esivela kwaSingleCare, ungathola okujwayelekile, uma kunqunywe udokotela, ngamanani aphansi njengama- $ 12 ngamathebulethi angama-30 wamandla we-5 mg.

I-Allegra, njengoXyzal, ingahlanganiswa neMedare noma izinhlelo zokuhweba, noma ileveli yokumboza ingahluka ngoba iyatholakala naphezu kwekhawunta. Ngaphandle komshwalense, igama lomkhiqizo i-Allegra lingabiza imali efinyelela ku- $ 30, kepha ngesigqebhezana se-SingleCare, ungalithola liphansi njengo- $ 8- $ 9 ngamathebulethi angama-30 wamandla ayi-180 mg, uma kunqunywe udokotela.

	Xyzal	I-Allegra
Ngokuvamile embozwe umshwalense?	Iyahluka kusuka kuhlelo lokuhlela	Iyahluka kusuka kuhlelo lokuhlela
Imbozwe ngokujwayelekile yi-Medicare?	Akunjalo	Akunjalo
Umthamo ojwayelekile	30, 5 amaphilisi mg	30, 180 mg amaphilisi
I-Medicare copay ejwayelekile	n / a	n / a
Izindleko ze-SingleCare	$ 12 +	$ 8- $ 24

Thola ikhadi lesaphulelo se-SingleCare

Imiphumela emibi ejwayelekile yeXyzal vs. Allegra

I-Xyzal, ngenkathi ithathwa njengesihlala phansi, isengadala ukozela kuze kufike 6% we iziguli . Iziguli kufanele zigweme ukushayela, ukugibela amabhayisikili, noma ezinye izinto eziyingozi ngenkathi zikuXyzal. Ezinye iziguli zingakhetha ukuthatha i-Xyzal yazo ebusuku ukunciphisa ukulinganiselwa ubuthongo okungakubeka emisebenzini yabo yansuku zonke.

Ngemuva kokumaketha ukuqapha weziguli zeXyzal zithole ukuthi ukushaya kwenhliziyo kanye ne-tachycardia, noma ukukhuphuka kwenhliziyo, kungahle kuhlotshaniswe nokusetshenziswa kweXyzal. Isipiliyoni sangemva kokumaketha futhi uthole ukuxhumana phakathi kwe-levocetirizine nokuquleka nokunye ukuphazamiseka kokunyakaza okuhlobene nesistimu yezinzwa emaphakathi.

Kubukeka sengathi akukho ukuxhumana phakathi kwe-Allegra kanye nokuphazamiseka kwenhliziyo noma kokuquleka njengoba kukhona neXyzal. I-Allegra inesimo esiphakeme kakhulu sokuhlanza nekhanda.

Izehlakalo zohudo zibukeka ziphansi kakhulu e-Allegra uma kuqhathaniswa neXyzal, yize kwenzeka kuzo zombili.

Ama-antihistamine wesizukulwane sesibili kungenzeka angasebenzi njengama-antihistamine esizukulwane sokuqala anjengeBenadryl (diphenhydramine) ekuphendukeni okunamandla kokungezwani komzimba.

Ishadi elilandelayo alihloselwe ukuthi libe uhlu olubanzi lwemiphumela emibi. Sicela uxhumane nodokotela wakho noma usokhemisi ukuthola eminye imininingwane ngemiphumela engemihle.

	Xyzal	I-Allegra
Imiphumela emibi	Kusebenza?	Imvamisa	Kusebenza?	Imvamisa
Ubuhlungu bekhanda	Akunjalo	n / a	Yebo	4% -10%
Ukuhlanza	Akunjalo	n / a	Yebo	4% -12%
Ukuhlungu obusemhlane	Akunjalo	n / a	Yebo	2% -2.5%
Ukuqunjelwa	Yebo	7%	Akunjalo	n / a
Khwehlela	Yebo	3%	Yebo	2% -4%
Uhudo	Yebo	4% -13%	Yebo	2% -4%
Isiyezi	Akunjalo	n / a	Yebo	amaphesenti amabili
Ukozela	Yebo	3% -6%	Akunjalo	n / a
I-Dyspepsia	Akunjalo	n / a	Yebo	5%
Ukukhathala	Akunjalo	n / a	Yebo	0.7% -3%
Imfiva	Yebo	4%	Yebo	2% -4.5%
Ukuqwasha	Yebo	1.2%	Akunjalo	n / a
I-Myalgia	Akunjalo	n / a	Yebo	2.6%
Ukushaya kancane	Yebo	Akuchaziwe	Akunjalo	n / a
Pharyngitis	Yebo	1% -2%	Yebo	2.4%
I-Rhinorrhea	Akunjalo	n / a	Yebo	1% -2%
Ukuquleka	Yebo	0.4% -2%	Akunjalo	n / a
I-Tachycardia	Yebo	Akuchaziwe	Akunjalo	n / a

Umthombo: Xyzal ( I-DailyMed I-Allegra ( I-DailyMed ).

Ukusebenzisana kwezidakamizwa kweXyzal vs. Allegra

I-Xyzal ne-Allegra ngayinye inokusebenzisana okuningi kwezidakamizwa, futhi eziningi zazo ziyasebenza kuzo zombili izidakamizwa. Ama-antihistamine ayizicindezeli zesistimu yezinzwa eziphakathi, futhi ukuxhumana okuningi kugxile kuzinqubo ze-CNS. Ngokuqondile, ukusebenzisa ama-antihistamine esizukulwane sesibili njenge-Xyzal noma i-Allegra namanye ama-antihistamine afana ne-hydroxyzine noma i-doxylamine angaba nomphumela obonakalayo wokudangala kwe-CNS.

Izimpawu zokucindezelwa kwe-CNS zingaveza njengokukhuluma okungaqondakali, ukungahambisani, isiyezi, noma ubunzima bokuhambisa imicabango. Ukusetshenziswa kwama-opioid noma ama-benzodiazepines nge-Xyzal noma i-Allegra nakho kungathuthukisa ukuvela kokudangala kwe-CNS. Ukusetshenziswa kwale mithi ndawonye kufanele kugwenywe.

Ama-antihistamine nawo anemiphumela ye-anticholinergic njengomlomo owomile, umphimbo owomile nokuncipha kokujuluka. Okunye ukuxhumana kungahle kube kubi kakhulu le miphumela. Ukusetshenziswa kwe-Xyzal noma i-Allegra ene-potassium citrate kungalimaza umphumela we-ulcerogenic we-potassium citrate. Le nhlanganisela kufanele igwenywe. Amathebulethi ezilimi ezingezansi zeNitroglycerin kungenzeka angasebenzi kahle esigulini esithatha iXyzal noma i-Allegra ngenxa yemiphumela ye-anticholinergic.

Uhlu olulandelayo lokusebenzisana kwezidakamizwa kungenzeka lungabi nakho konke ukuxhumana okungenzeka. Sicela uxhumane nodokotela wakho noma usokhemisi ukuthola uhlu oluphelele.

Izidakamizwa	Isigaba Sezidakamizwa	Xyzal	I-Allegra
I-Aclidinium	I-Anticholinergic	Yebo	Yebo
I-Amantadine	Ummeli we-Anti-Parkinson	Yebo	Yebo
I-Dextroamphetamine I-Methylphenidate	Ama-Amphetamines	Yebo	Yebo
I-Azelastine	Umphikisi we-H1	Yebo	Yebo
I-Brexanolone	I-GABA-A Modulator Yokwamukela	Yebo	Yebo
I-Bromperidol I-Droperidol	Ama-antipsychotic	Yebo	Yebo
I-Buprenorphine I-Hydrocodone I-Oxycodone	Ama-opioid	Yebo	Yebo
I-Cannabidiol Insangu Dronabinol	Ama-cannabinoids	Yebo	Yebo
I-Clozapine	I-antipsychotic engajwayelekile	Yebo	Yebo
I-Diphenhydramine I-Chlorpheniramine I-Doxylamine I-Hydroxyzine	Ama-antihistamine	Yebo	Yebo
Magnesium Sulphate	I-Laxative	Yebo	Yebo
I-Minocycline	Imithi elwa namagciwane	Yebo	Yebo
I-Nitroglycerin	IVasodilator	Yebo	Yebo
I-Potassium Citrate	Umenzeli we-alkalinizing	Yebo	Yebo
Pramipexole URopinirole	Ama-Agonists eDopamine	Yebo	Yebo

Izexwayiso zeXyzal ne-Allegra

Iziguli ezinesifo sezinso esikhona nokwehla komsebenzi wezinso kufanele zigweme ukusebenzisa iXyzal. Odokotela bangalungisa umthamo wakho ngokuya ngesilinganiso somsebenzi wakho wezinso owaziwa ngokuthi i-creatinine clearance (CrCl). Ukozela kungenzeka ngenkathi uthatha iXyzal, kanti iziguli kufanele zikugweme ukushayela.

Kokubili i-Xyzal ne-Allegra kufanele kugwenywe ezigulini ezinobunzima bokukhipha isinye. Imiphumela yabo ye-anticholinergic ingenza lokhu kube kubi kakhulu.

Utshwala, futhi obucindezela i-CNS, kufanele bugwenywe ezigulini ezithatha iXyzal noma i-Allegra.

I-Xyzal ne-Allegra ingasetshenziselwa ukwelapha i-allergen rhinitis noma i-urticaria lapho ukhulelwe. Kufanele uhlale uthintana nodokotela wakho ngaphambi kokuphuza imithi ngesikhathi ukhulelwe.

Imibuzo ebuzwa njalo mayelana neXyzal vs. Allegra

Kuyini uXyzal?

I-Xyzal iyi-anti-sedamine esezingeni eliphansi, yesizukulwane sesibili esetshenziselwa ukwelapha i-rhinitis yokungezwani komzimba ngenxa yokungezwani komzimba ngezikhathi ezithile zonyaka noma ezingapheli, ukungezwani komzimba nesikhumba okungahambi kahle, kanye ne-urticaria engapheli yesifo. Iyatholakala njengethebhulethi kanye nesisombululo somlomo kukho konke ukwenziwa kwencwadi kadokotela naku-counter.

Yini i-Allegra?

I-Allegra iyi-anti-histamine yesizukulwane sesibili engasetshenziswanga ukwelapha i-allergen rhinitis ngenxa yokungezwani komzimba nezikhathi ezithile noma okungapheli, ukungezwani komzimba nesikhumba okungahambi kahle, kanye ne-urticaria engapheli yesifo. Iyatholakala njengethebhulethi nokumiswa ngomlomo kukho konke ukwenziwa kwencwadi kadokotela nangaphezulu.

Ngabe iXyzal ne-Allegra ziyefana?

Ngenkathi womabili engama-antihistamine wesizukulwane sesibili, awafani ncamashi. IXyzal ihlezi kakhulu kune-Allegra. Idatha yokuthengisa ngemuva kokuphakamisa iphakamisa ukuxhumana phakathi kweXyzal nokuquleka kanye nemiphumela yenhliziyo njengokunyuka kwenhliziyo nokushaywa. Le miphumela ayixhunywanga ne-Allegra.

Ngabe iXyzal noma i-Allegra ingcono?

Lapho kuqhathaniswa u-Xyzal no-Allegra ngemiphumela yabo ku-allergen rhinitis ebangelwa impova yotshani, kwachazwa ukuthi zombili zazisebenza ngokulinganayo ngemuva nje kokufakwa kwesikali, kepha u-Xyzal ubonakala enesikhathi eside esenziwayo, okuholela ekukhululekeni okuhlala isikhathi eside kwezimpawu.

Ngingayisebenzisa iXyzal noma i-Allegra ngenkathi ngikhulelwe?

I-Xyzal ne-Allegra kubhekwa njengokuphephile ekukhulelweni ukwelapha i-urticaria kanye ne-allergen rhinitis, yize kufanele uhlale uthintana nodokotela wakho ngaphambi kokuthatha le mithi lapho ukhulelwe.

Ngingayisebenzisa i-Xyzal noma i-Allegra ngotshwala?

Ukusetshenziswa kotshwala ngasikhathi sinye ngeXyzal noma i-Allegra akunconyiwe njengoba imiphumela emibi ye-CNS yazo zombili lezi zinto izothuthukiswa. Lokhu kungaholela enkulumweni yokukhuluma noma isiyezi.

Ngabe uXyzal unamandla kune-Allegra?

I-Xyzal ne-Allegra ziyasebenza ngayinye ekwelapheni ukusabela okuhlobene nokungezwani komzimba, kepha u-Xyzal unesikhathi eside esenziwayo. Lokhu kuholela esigulini esithola ukukhululeka kusuka kumthamo owodwa isikhathi eside.

Kungani uXyzal ethathwa ebusuku?

Iziguli ezingaba ngu-6% zizokuzwa ukozela okuphawuliwe lapho zithatha i-Xyzal, futhi ngenxa yalesi sizathu, kunconywa ukuthi zithathwe ebusuku.

Ngabe uXyzal angadala ukucindezeleka?

Idatha yokuthengisa ngemuva kokuphakamisa iphakamise ukuthi iziguli ezingaphansi kuka-1% zibika ukucindezeleka ngenxa yokuthatha iXyzal. Lokhu akufanele kudidaniswe nokudangala kohlelo oluphakathi lwezinzwa, okungabonakala njengenkulumo engacacile, ukudideka, nesiyezi.