I-Diclofenac vs. ibuprofen: Umehluko, ukufana, nokuthi yikuphi okungcono kuwe
Izidakamizwa Vs. UmnganiUkubuka konke kwezidakamizwa nokwehluka okuyinhloko | Izimo zilashwa | Ukusebenza | Ukutholakala komshuwalense nokuqhathaniswa kwezindleko | Okuqhamuka uma udla imishanguzo | Ukusebenzisana kwezidakamizwa | Izexwayiso | Imibuzo evame ukubuzwa
Njengoba kunezinketho eziningi zokwelashwa kwesifo samathambo, kungaba nzima ukukhetha umuthi omuhle kakhulu kuwe. Uma uzwa ubuhlungu be-arthritis njalo, unganconywa umuthi we-nonsteroidal anti-inflammatory (NSAID) njenge-diclofenac noma ibuprofen. Le mithi isebenza ngokunciphisa ukukhiqizwa kwama-prostaglandin, noma amakhemikhali abhekene nokuvuvukala.
I-Diclofenac ne-ibuprofen kusetshenziswa ama-NSAID ajwayelekile okwelapha ukuvuvukala nobuhlungu kusuka i-osteoarthritis nesifo samathambo. Zombili lezi zidakamizwa zingama-NSAID angakhethi okusho ukuthi avimba ama-enzyme e-COX-2 ne-COX-1 abhekene nokukhiqizwa kwe-prostaglandin. Ngoba i-enzyme ye-COX-1 nayo inemiphumela yokuvikela ulwelwesi lwesisu, ukuvimba le-enzyme kungadala imiphumela emibi yamathumbu.
Uyini umehluko omkhulu phakathi kwe-diclofenac vs. ibuprofen?
I-Diclofenac (isigqebhezana se-diclofenac) ngumuthi kadokotela ohamba ngegama lomkhiqizo, iVoltaren. Itholakala njengomuthi ojwayelekile osetshenziselwa ukwelapha i-osteoarthritis, isifo samathambo, ne-ankylosing spondylitis, noma isifo samathambo esithinta umgogodla. I-Diclofenac sodium iza njengethebhulethi ekhishwe ukubambezeleka, ithebhulethi ekhishwa enwetshiwe, nejel noma isisombululo. I-FDA ivunyelwe abantu abadala abaneminyaka engu-18 nangaphezulu.
Ibuprofen (ibuprofen coupon) iyi-NSAID evame ukuthathwa engathengwa ngaphezu kwe-counter (OTC) noma ngencwadi kadokotela. Ibuprofen ingatholakala ngegama layo lomkhiqizo, i-Advil noma i-Motrin. I-OTC ibuprofen ingasetshenziselwa ubuhlungu obuncane nomkhuhlane ngenkathi i-prescription-strength ibuprofen ingasetshenziselwa ubuhlungu obukhulu kakhulu kusuka ku-arthritis. Kuvunyelwe i-FDA ukwelapha ubuhlungu kubantu abadala nasezinyangeni eziyisithupha nangaphezulu.
| Umehluko omkhulu phakathi kwe-diclofenac vs. ibuprofen | ||
|---|---|---|
| I-Diclofenac | Ibuprofen | |
| Isigaba sezidakamizwa | Izidakamizwa ezingezona ukuvuvukala (i-NSAID) | Izidakamizwa ezingezona ukuvuvukala (i-NSAID) |
| Isimo somkhiqizo / ejwayelekile | I-Brand ne-generic iyatholakala | I-Brand ne-generic iyatholakala |
| Ngubani igama elijwayelekile? Ngubani igama lomkhiqizo? | I-Diclofenac I-Voltaren | Ibuprofen I-Advil, iMotrin |
| Izidakamizwa zingena ngaziphi izinhlobo? | Ithebhulethi yomlomo, ithebhulethi yomlomo eboshwe enteric Ijeli yezindaba Isixazululo se-Topical | Ithebhulethi yomlomo Ama-capsules omlomo Ukumiswa ngomlomo |
| Uyini umthamo ojwayelekile? | 50 mg kabili noma kathathu ngosuku | 400 kuya ku-800 mg njalo emahoreni ayisithupha kuya kwayisishiyagalombili |
| Yelashwa isikhathi esingakanani? | Nsuku zonke njengoba uyalelwe udokotela wakho | Akudluli izinsuku eziyi-10 noma njengokuyalelwa ngudokotela wakho |
| Ubani ovame ukusebenzisa umuthi? | Abantu abadala | Abantu abadala |
Ufuna intengo enhle ku-Diclofenac?
Bhalisela izexwayiso zamanani eDiclofenac bese uthola ukuthi intengo ishintsha nini!
Thola izexwayiso zentengo
Izimo eziphathwa i-diclofenac ne-ibuprofen
I-Diclofenac (yini i-diclofenac?) Isetshenziselwa ukwelapha i-osteoarthritis, i-rheumatoid arthritis, ne-ankylosing spondylitis. Kungasiza futhi ekwelapheni i-dysmenorrhea noma ubuhlungu obuvela ezinkalweni zokuya esikhathini kanye ne-migraines. I-Ibuprofen (yini ibuprofen?) Ingaphinde ilaphe i-osteoarthritis, isifo samathambo, kanye ne-ankylosing spondylitis. Njenge-painkiller ye-NSAID, i-ibuprofen nayo ingaphatha i-dysmenorrhea kanye ne-migraines kanye nobuhlungu obuncane nomkhuhlane emithamo engeyona kadokotela.
| Isimo | I-Diclofenac | Ibuprofen |
| I-osteoarthritis | Yebo | Yebo |
| Isifo samathambo | Yebo | Yebo |
| I-Ankylosing spondylitis | Yebo | Ngaphandle kwelebula |
| I-Dysmenorrhea | Yebo | Yebo |
| Migraine | Yebo | Yebo |
Ingabe i-diclofenac noma ibuprofen isebenza kangcono?
I-Diclofenac idinga ukwelashwa ngumhlinzeki wakho wezokunakekelwa kwempilo futhi ibhekwa njenge-NSAID enamandla kakhulu kune-ibuprofen. Nge-arthritis, i-diclofenac ivame ukukhishwa njenge-25 kuye ku-50 mg kuze kufike kumthamo wansuku zonke ka-150 mg. I-Ibuprofen inqunywe kumithamo ephakeme ka-800 mg kuze kufike kumthamo wansuku zonke ka-3200 mg.
Phakathi ku ukuhlaziywa kwe-meta kusuka kuJenaliya ye-Arthritis Research and Therapy, i-diclofenac itholakale isebenza kangcono kune-ibuprofen yokuphumuza izinhlungu ze-arthritic. Ucwaningo lubuyekeze idatha kusuka ezifundweni eziyi-176 ezineziguli ezingaphezu kwe-146,524. Ingozi yemiphumela ehlobene nesisu nayo itholakale iphansi nge-diclofenac uma iqhathaniswa ne-ibuprofen. I-Diclofenac itholakale isebenza kangcono uma iqhathaniswa namanye ama-NSAID afana ne-celecoxib ne umabhebhana .
Kokubili i-diclofenac ne-ibuprofen ziyaqhathaniswa ngemithamo efanele. Xoxa ngezinketho zakho zokwelashwa nodokotela wakho njengoba umuntu engakusebenzela kangcono.
Ufuna intengo engcono kakhulu ku-ibuprofen?
Bhalisela izaziso zamanani e-ibuprofen bese uthola ukuthi intengo ishintsha nini!
Thola Izaziso Zentengo
Ukuqhathaniswa kanye nezindleko zokuqhathaniswa kwe-diclofenac vs. ibuprofen
Iningi lezinhlelo zemishwalense yezokwelapha nezempilo lifaka uhlobo olujwayelekile lwe-diclofenac. Izindleko ezijwayelekile zokuthengisa ze-diclofenac zingaba cishe ngama- $ 60. Lezi zindleko zingehliselwa ku- $ 20-30 ngekhadi lesigqebhezana le-SingleCare.
Kwi-ibuprofen ejwayelekile, izindleko zivame ukumbozwa yizinhlelo eziningi zemithi nezomshuwalense. Ngaphandle komshuwalense, izindleko ezijwayelekile zokuthengisa zingasuka ku- $ 3 ziye cishe ku- $ 7 ngebhodlela ngalinye. Kodwa-ke, ngesigqebhezana se-ibuprofen, intengo ingaba ngaphansi kwe- $ 3.
Thola ikhadi lesaphulelo sakwaSingleCare
| I-Diclofenac | Ibuprofen | |
| Ngokuvamile embozwe umshwalense? | Yebo | Yebo |
| Imbozwe ngokujwayelekile yi-Medicare? | Yebo | Yebo |
| Umthamo ojwayelekile | 50 mg | 400-800 mg |
| I-Medicare copay ejwayelekile | $ 3- $ 46 | $ 0- $ 22 |
| Izindleko ze-SingleCare | $ 20-30 | $ 3 |
Imiphumela emibi ye-diclofenac ne-ibuprofen
Imiphumela emibi ejwayelekile ye-diclofenac ne-ibuprofen ifaka phakathi imiphumela emibi yamathumbu efana nohudo, ukuqunjelwa, ukuqunjelwa noma igesi, ubuhlungu besisu noma amajaqamba, isilungulela nokuqunjelwa. Le mithi ingathinta futhi uhlelo oluphakathi lwezinzwa (CNS) futhi idale imiphumela emibi efana nesiyezi nokuphathwa yikhanda. Eminye imiphumela emibi ibandakanya i-pruritus (ukulunywa) ne-edema (ukuvuvukala ezandleni, izingalo, imilenze, noma izinyawo).
Imiphumela emibi kakhulu ibandakanya izilonda zesisu nezinkinga zezinso noma zesibindi. Le miphumela emibi kungenzeka ukuthi yenzeke uma unomlando wayo noma uthatha eminye imithi engasebenzisana nama-NSAID.
| I-Diclofenac | Ibuprofen | |||
| Imiphumela emibi | Kusebenza? | Imvamisa | Kusebenza? | Imvamisa |
| Uhudo | Yebo | 1% -10% | Yebo | 1% -3% |
| Ukugaya ukudla | Yebo | 1% -10% | Yebo | 1% -3% |
| Ukuqhuma kwesisu | Yebo | 1% -10% | Yebo | 1% -3% |
| Amajaqamba esisu | Yebo | 1% -10% | Yebo | 1% -3% |
| Ukuqunjelwa | Yebo | 1% -10% | Yebo | 1% -3% |
| Isilungulela | Yebo | 1% -10% | Yebo | 3% -9% |
| Isicanucanu | Yebo | 1% -10% | Yebo | 3% -9% |
| Ukuhlanza | Yebo | 1% -10% | Yebo | 1% -3% |
| Ubuhlungu bekhanda | Yebo | 1% -10% | Yebo | 1% -3% |
| Isiyezi | Yebo | 1% -10% | Yebo | 3% -9% |
| Ukulunywa | Yebo | 1% -10% | Yebo | 1% -3% |
| I-Edema | Yebo | 1% -10% | Yebo | 1% -3% |
Lokhu kungenzeka kungabi uhlu oluphelele. Xhumana nodokotela wakho noma wemithi ngeminye imiphumela emibi.
Umthombo: DailyMed ( I-Diclofenac ), IDailyMed ( Ibuprofen )
Ukusebenzisana kwezidakamizwa kwe-diclofenac vs. ibuprofen
I-Diclofenac ne-ibuprofen ngama-NSAID angasebenzisana nemithi yengcindezi yegazi efana ne-angiotensin-converting enzyme (ACE) inhibitors, i-angiotensin receptor blockers (ARBs), i-beta blockers kanye ne-diuretics. Ama-NSAID anganciphisa ukucindezela kwegazi ukwehlisa imiphumela yale mithi eqeda umfutho wegazi ophakeme.
Ukuthatha ama-NSAID nge-thinner yegazi njenge-aspirin noma i-warfarin kungandisa ingozi yokuphuma kwegazi. Le mithi ingasebenzisana futhi inyuse ubungozi bezilonda zesisu. Ukuthatha ama-NSAID ngama-SSRI antidepressants nakho kungandisa ingozi yokuphuma kwegazi.
Ama-NSAID nawo angasebenzisana neminye imithi futhi andise amazinga awo emzimbeni. Ukuthatha ama-NSAID ngemithi efana ne-lithium, i-digoxin, ne-methotrexate kungakhuphula ubungozi bemiphumela emibi.
Xhumana nodokotela noma usokhemisi uma uthatha noma yimiphi imithi ngaphambi kokuqala i-NSAID.
| Izidakamizwa | Isigaba Sezidakamizwa | I-Diclofenac | Ibuprofen |
| I-Aspirin | I-Antiplatelet | Yebo | Yebo |
| I-Warfarin | I-Anticoagulant | Yebo | Yebo |
| I-Paroxetine Sertraline I-Escitalopram I-Fluoxetine | I-antidepressant ekhethiwe ye-serotonin reuptake inhibitor (SSRI) | Yebo | Yebo |
| I-Venlafaxine I-Desvenlafaxine | ISerotonin-norepinephrine reuptake inhibitor (SNRI) i-antidepressant | Yebo | Yebo |
| Enalapril I-Lisinopril I-Benazepril | I-Angiotensin-converting enzyme (ACE) inhibitors | Yebo | Yebo |
| ILosartan Valsartan I-Irbesartan I-Candesartan | Ama-Angiotensin receptor blockers (ama-ARB) | Yebo | Yebo |
| I-Metoprolol ICarvedilol I-Atenolol | Ama-beta blockers | Yebo | Yebo |
| I-Hydrochlorothiazide UFurosemide | Izidakamizwa | Yebo | Yebo |
| ILithium | Isimisi sokuqina | Yebo | Yebo |
| IMethotrexate | I-Antimetabolite | Yebo | Yebo |
| I-Digoxin | I-glycoside yenhliziyo | Yebo | Yebo |
Lokhu kungenzeka kungabi uhlu oluphelele lwako konke ukuhlangana kwezidakamizwa okungenzeka. Xhumana nodokotela ngayo yonke imithi okungenzeka uyayiphuza.
Izexwayiso ze-diclofenac ne-ibuprofen
Ukusebenzisa ama-NSAID kungaholela engcupheni eyengeziwe yemicimbi yenhliziyo efana nokuhlaselwa yisifo senhliziyo nokushaywa unhlangothi, ikakhulukazi uma unomlando wazo wezokwelapha. Ama-NSAID angabhebhethekisa ukwehluleka kwenhliziyo noma aguqule imiphumela yemithi yengcindezi yegazi. Ama-NSAID nawo angakhuphula ubungozi bezehlakalo zesisu njengokuphuma kwegazi noma izilonda esiswini nasemathunjini.
I-Diclofenac ne-ibuprofen kufanele igwenywe noma ibhekwe kubantu abanezinkinga zesibindi noma izinso. Ukuthatha ama-NSAID kungandisa ingozi yobuthi esibindini nasezinso.
Ama-NSAID akufanele asetshenziswe ngesikhathi sokukhulelwa sekwephuzile. Ukuthatha ama-NSAID ngemuva kwamasonto angama-30 ekhulelwe kungadala ukuvalwa ngaphambi kwesikhathi kwe-ductus arteriosus, isitsha segazi enhliziyweni yesisu. Khuluma nodokotela wakho mayelana nokusebenzisa ama-NSAID ngesikhathi sokuqala sokukhulelwa njengoba kufanele kuthathwe kuphela uma izinzuzo ezingaba khona zidlula izingozi.
Imibuzo ebuzwa njalo mayelana ne-diclofenac vs. ibuprofen
Yini i-diclofenac?
I-Diclofenac iyi-NSAID esetshenziselwa ukwelapha isifo samathambo kubantu abadala. I-FDA ivunyelwe i-osteoarthritis, i-rheumatoid arthritis, ne-ankylosing spondylitis. I-Diclofenac ivame ukuza njengethebhulethi yomlomo kadokotela noma i-gel yama-topical futhi isetshenziswa kabili noma kathathu ngosuku.
Kuyini ibuprofen?
I-Ibuprofen yi-NSAID esetshenziselwa ukwelapha ubuhlungu nokuvuvukala kwesifo samathambo. Iyatholakala ngaphezu kwekhawunta ukwelapha ubuhlungu nomkhuhlane kubantu abadala nasezinganeni. Ibuprofen yamandla kadokotela nayo iyatholakala futhi ivame ukuthathwa njalo emahoreni ayisithupha kuya kwayisishiyagalombili.
Ngabe i-diclofenac ne-ibuprofen ziyefana?
Cha, i-diclofenac ne-ibuprofen azifani. I-Diclofenac iyi-NSAID kadokotela ngenkathi ibuprofen ingathengwa ngaphezulu kwe-counter noma ngencwadi kadokotela. I-Diclofenac inqunyelwe abantu abadala kuphela ngenkathi ibuprofen ingasetshenziswa ezinganeni.
Ingabe i-diclofenac vs. ibuprofen ingcono?
I-Diclofenac ibhekwa njengamandla amakhulu kune-ibuprofen futhi idinga ukuphuzwa kabili noma kathathu ngosuku. I-Ibuprofen imvamisa idinga ukuphuzwa ngemithamo ephezulu ukwelapha ubuhlungu besifo samathambo.
Ngingayisebenzisa i-diclofenac vs. ibuprofen ngenkathi ngikhulelwe?
Ama-NSAID afana ne-diclofenac ne-ibuprofen kufanele agwenywe ngesikhathi sokukhulelwa. Ukuthatha ama-NSAID phakathi nengxenye yokugcina yokukhulelwa kungadala izinkinga zenhliziyo yengane. Xhumana nodokotela uma ukhulelwe.
Ngingayisebenzisa i-diclofenac vs. ibuprofen ngotshwala?
I-Diclofenac ne-ibuprofen kufanele kugwenywe ngotshwala. Ukuphuza utshwala ngama-NSAID kungaholela engcupheni eyengeziwe yokopha neminye imiphumela emibi efana nesiyezi nokuphathwa yikhanda.
Ngabe i-diclofenac ingcono kune-ibuprofen yezinhlungu emuva?
I-Diclofenac ivunyiwe yi-FDA yesifo samathambo esithinta umgogodla. Kungasebenza kakhulu kumithamo ephansi ngokuqhathaniswa ne-ibuprofen. I-Diclofenac ne-ibuprofen, njengama-NSAID amaningi, ingasiza ekuphathweni kobuhlungu nokuvuvukala.
Ingabe i-diclofenac iphephile kune-ibuprofen?
I-Diclofenac idinga ukuhlolwa nodokotela ozokusebenzisa. I-Ibuprofen ingaphezu kwekhawunta ngakho-ke ithathwa njengevikelekile ezifweni ezijwayelekile ezinjengezinhlungu noma imfiva.
Ngingathatha i-diclofenac ne-ibuprofen?
Cha. IDiclofenac ne-ibuprofen akufanele zithathwe ndawonye ngoba zisebenza ngendlela efanayo. Ukuzihlanganisa kungandisa ubungozi bezehlakalo ezimbi nemiphumela emibi.
