INaproxen vs. ibuprofen: Umehluko, ukufana, nokuthi yikuphi okungcono kuwe
Izidakamizwa Vs. UmnganiUkubuka konke kwezidakamizwa nokwehluka okuyinhloko | Izimo zilashwa | Ukusebenza | Ukutholakala komshuwalense nokuqhathaniswa kwezindleko | Okuqhamuka uma udla imishanguzo | Ukusebenzisana kwezidakamizwa | Izexwayiso | Imibuzo evame ukubuzwa
INaproxen ne-ibuprofen ngama-NSAID (izidakamizwa ezingezona ukuvuvukala) ezingezona ezokulwa nokuvuvukala) ezisetshenziselwa ukwelapha ubuhlungu nokuvuvukala kusuka ezimeni ezahlukahlukene. Ama-NSAID asebenza ngokuvimba ikhemikhali elibizwa nge-prostaglandin. I-Prostaglandin ibangela ubuhlungu nokuvuvukala. Ngokuvimba i-prostaglandin, ama-NSAID asiza ekwelapheni ubuhlungu nokuvuvukala. Kokubili i-naproxen ne-ibuprofen kwaziwa njengama-NSAID futhi anokufana okuningi, kepha anokuhluka okuthile.
Uyini umehluko omkhulu phakathi kwe-naproxen vs. ibuprofen?
INaproxen, noma i-naproxen sodium, yaziwa ngegama lomkhiqizo, iNaprosyn, kanye ne-over-the-counter njengo-Aleve. Itholakala futhi ngendlela ejwayelekile kuphela (ngencwadi kadokotela, kanye ne-OTC kumthamo ophansi) futhi ngokuhlanganiswa neminye imithi. I-Ibuprofen yaziwa ngegama lomkhiqizo iMotrin ne-Advil, futhi iyatholakala futhi ifomu elejwayelekile kuphela futhi lihlangene neminye imithi. Ukulinganisa kuyahluka ngokukhombisa, futhi umthamo we-OTC uphansi kunomthamo kadokotela. Futhi, ibuprofen yenza okufushane futhi idosiwe kaningi kune-naproxen, esebenza isikhathi eside futhi engancishiswa kaningi.
Ngoba zombili lezi zidakamizwa zitholakala ezinhlanganisweni ezahlukahlukene, njengemithi ehlukahlukene yokukhwehlela nemithi ebandayo kanye nokwakhiwa kokulala, lapho ukhetha umkhiqizo we-OTC, kuwumqondo omuhle ukubonisana nosokhemisi wakho ukuqinisekisa ukuthi ukhetha umkhiqizo ofanele izimpawu. Futhi, imikhiqizo eminingi ehlanganisiwe equkethe i-naproxen noma i-ibuprofen ingaqukatha umkhiqizo ongahle ungahambisani nezimo zakho zezokwelapha noma eminye imithi oyisebenzisayo. Lapho ukhetha umuthi wezingane, ngaso sonke isikhathi thintana nodokotela wezingane noma wemithi ukuthola imithamo efanele ngokuya ngeminyaka yengane nesisindo sayo.
| Umehluko omkhulu phakathi kwe-naproxen vs. ibuprofen | ||
|---|---|---|
| I-Naproxen | Ibuprofen | |
| Isigaba sezidakamizwa | I-NSAID | I-NSAID |
| Isimo somkhiqizo / ejwayelekile | Umkhiqizo nokujwayelekile | Umkhiqizo nokujwayelekile |
| Ngubani igama lomkhiqizo? | U-Aleve, u-Anaprox DS, uNaprosyn | UMotrin, u-Advil |
| Izidakamizwa zingena ngaziphi izinhlobo? | Amathebulethi, ama-caplets, ama-softgels | Amathebulethi, ama-caplets, ama-softgel, amafomu oketshezi |
| Uyini umthamo ojwayelekile? | Abantu abadala i-OTC: 220 mg njalo emahoreni ayisishiyagalombili kuya kwayi-12 Abantu abadala Rx: 250-500 mg njalo emahoreni ayi-12 * Thatha nokudla | Abadala i-OTC: 200 mg njalo emahoreni ama-4 kuye kwayi-6 (ubuningi be-1200 mg ngosuku) Abantu abadala i-Rx: 400-800 mg izikhathi ezi-3 kuya kwezi-4 nsuku zonke (ubuningi bama-3200 mg ngosuku - thintana noDkt. * Thatha nokudla |
| Yelashwa isikhathi esingakanani? | Iyahluka ngokukhombisa | Iyahluka ngokukhombisa |
| Ubani ovame ukusebenzisa umuthi? | Abantu abadala, izingane ezineminyaka engu-2 nangaphezulu | Abantu abadala, izingane izinyanga eziyisithupha nangaphezulu |
Ufuna intengo engcono kakhulu ku-ibuprofen?
Bhalisela izaziso zamanani e-ibuprofen bese uthola ukuthi intengo ishintsha nini!
Thola izexwayiso zentengo
Izimo eziphathwa yi-naproxen ne-ibuprofen
INaproxen ne-ibuprofen yimithi emibili ethandwayo esetshenziselwa ukwelapha ubuhlungu nokuvuvukala. Yomibili le mithi ikhonjisiwe ukuqeda izimpawu nezimpawu zesifo samathambo, i-osteoarthritis, ubuhlungu obumaphakathi kuya kokulingene, kanye ne-dysmenorrhea eyinhloko (amajaqamba okuya esikhathini). INaproxen nayo ikhonjisiwe ukukhululeka kwezimpawu ze-tendonitis, bursitis, gout acute, ankylosing spondylitis, kanye nePolyarticular juvenile idiopathic arthritis.
| Isimo | I-Naproxen | Ibuprofen |
| Isifo samathambo I-osteoarthritis | Yebo | Yebo |
| I-tendonitis I-Bursitis I-gout enamandla | Yebo | Ngaphandle kwelebula |
| I-Ankylosing spondylitis I-Polyarticular juvenile idiopathic arthritis | Yebo | Ngaphandle kwelebula |
| Ubuhlungu obumnene kuya obulinganiselayo | Yebo | Yebo |
| I-dysmenorrhea eyinhloko | Yebo | Yebo |
Ingabe i-naproxen noma i-ibuprofen iyasebenza kakhulu?
Izilawuli ezimbili ezingahleliwe, eziyimpumputhe, ezilawulwa nge-placebo izifundo uqhathanisa i-naproxen ne-ibuprofen ye-osteoarthritis yamadolo, wabheka yomibili le mithi ngesonto elilodwa, kumithamo ye-OTC (engezansi), futhi wathola ukuthi yomibili le mithi yayisebenza ekwehliseni ubuhlungu. INaproxen itholakale isebenza ngempumelelo ethe xaxa, futhi isebenza kangcono ekunciphiseni izinhlungu zasebusuku. Zombili lezi zidakamizwa zazibekezeleleke kahle.
Esinye isifundo esincane kuqhathanisa i-naproxen ne-ibuprofen ithole yomibili le mithi ilusizo ekwehliseni ukuqina, izinhlungu zokuphumula, ubuhlungu bokunyakaza, izinhlungu zasebusuku, ukuphazamiseka kwalesi sifo ngemisebenzi yansuku zonke, kanye nobukhulu besifo jikelele. INaproxen itholakale iphumelela kakhulu kulolu cwaningo. Iziguli eziningi zithole imiphumela emibi, ikakhulukazi izingqinamba ze-GI ezimnene; Kodwa-ke, isiguli esisodwa esithatha i-naproxen siphume igazi nge-GI.
Esikhathini seminyaka engama-20 ukubuyekezwa kwama-NSAID , ababhali babona ubunzima ekukhetheni i-NSAID futhi bathi Kaningi, ukukhethwa kwe-analgesic kusekelwe kokuhlangenwe nakho komuntu siqu kunobufakazi. Baqhubeka bathi izifundo eziningi zenzelwe izimo ezinzima, kunezimo ezingapheli, nokuthi lezi zifundo azikwazi ukunquma ngempumelelo ukuthi iyiphi i-NSAID engcono kakhulu. Ababhali bagcizelela ukubaluleka kokusebenzisa umthamo ophansi kakhulu we-NSAID isikhathi esifushane kakhulu. Bancoma ukuthi lapho iTylenol (i-acetaminophen) inganele, kungcono ukuqala ngomthamo ophansi we-ibuprofen (kanye nemithi yokuvikela isisu kulabo abasengozini enkulu yemiphumela ye-GI).
Ngoba ubufakazi abuhlangani kahle, umuthi osebenza kahle kakhulu kufanele unqunywe udokotela wakho, ozobheka isimo sakho sezokwelapha nomlando, neminye imithi oyiphuzayo.
Ufuna intengo engcono kakhulu ku-naproxen?
Bhalisela izexwayiso zentengo ye-naproxen bese uthola ukuthi intengo ishintsha nini!
Thola izexwayiso zentengo
Ukuqhathaniswa kanye nezindleko zokuqhathaniswa kwe-naproxen vs. ibuprofen
INaproxen ne-ibuprofen zinamanani entengo, kuzo zombili izinhlobo ze-OTC neRx. Zombili lezi zidakamizwa zivame ukumbozwa umshwalense kanye ne-Medicare Part D kwifomu lamandla kadokotela. Umuthi ojwayelekile we-naproxen ungaba ngamaphilisi angama-60, 500 mg futhi ubize cishe u- $ 30- $ 40 ngaphandle komshwalense. Imithi ejwayelekile ye-ibuprofen ingaba yamaphilisi angama-30, 800 mg futhi ibiza cishe u- $ 18 ngaphandle komshwalense. Ama-copays e-Insurance ne-Medicare Part D azohluka ngokuya ngohlelo. Ungonga imali usebenzisa ikhuphoni le-SingleCare ku-naproxen naku-ibuprofen.
| I-Naproxen | Ibuprofen | |
| Ngokuvamile embozwe umshwalense? | Yebo - amandla kadokotela kuphela | Yebo - amandla kadokotela kuphela |
| Imbozwe ngokujwayelekile yi-Medicare Part D? | Yebo - amandla kadokotela kuphela | Yebo - amandla kadokotela kuphela |
| Umthamo ojwayelekile | # 60, 500 mg amaphilisi | # 30, 800 mg amaphilisi |
| Ingxenye ejwayelekile ye-Medicare copay Part D | $ 0-20 | $ 0-22 |
| Izindleko ze-SingleCare | $ 9- $ 20 | $ 5- $ 8 |
Imiphumela emibi ye-naproxen vs. ibuprofen
Ngoba i-naproxen ne-ibuprofen womabili angama-NSAID, imiphumela emibi iyefana kuyo yomibili le mithi. Imiphumela emibi evame kakhulu isisu (GI) efaka isilungulela, ubuhlungu besisu, ukuqunjelwa, kanye / noma uhudo. Ezinye iziguli nazo ziba nesicanucanu, isiyezi noma ikhanda.
Xhumana nochwepheshe wezokunakekelwa kwempilo ukuthola uhlu oluphelele lwemiphumela engemihle.
| I-Naproxen | Ibuprofen | |||
| Imiphumela emibi | Kusebenza? | Imvamisa | Kusebenza? | Imvamisa |
| Isilungulela | Yebo | 3-9% | Yebo | 1-16% |
| Isicanucanu | Yebo | 3-9% | Yebo | 1-16% |
| Ubuhlungu besisu | Yebo | 3-9% | Yebo | 1-16% |
| Ukuqunjelwa | Yebo | 3-9% | Yebo | 1-16% |
| Uhudo | Yebo | <3% | Yebo | 1-16% |
| Ubuhlungu bekhanda | Yebo | 3-9% | Yebo | 1-3% |
| Isiyezi | Yebo | 3-9% | Yebo | 3-9% |
| Ukozela | Yebo | 3-9% | Akunjalo | - |
| Pruritus (ukulunywa) | Yebo | 3-9% | Yebo | 3-9% |
| Tinnitus (kukhala ezindlebeni) | Yebo | 3-9% | Yebo | 1-3% |
| I-Edema (ukuvuvukala) | Yebo | 3-9% | Yebo | 1-3% |
| I-Dyspnea (ukuphefumula okuncane) | Yebo | 3-9% | Akunjalo | - |
Umthombo: DailyMed (naproxen) , I-DailyMed ( ibuprofen )
Ukusebenzisana kwezidakamizwa kwe-naproxen vs. ibuprofen
INaproxen noma ibuprofen akufanele ithathwe nge-anticoagulant efana neCoumadin (warfarin), ngoba lokhu kungakhuphula ubungozi bokuphuma kwegazi. Ukuthatha i-naproxen noma i-ibuprofen namanye ama-NSAID, njenge-aspirin, kungakhuphula nengozi yokuphuma kwegazi kanye nemiphumela emibi ye-GI. INaproxen noma ibuprofen ingaxhumana nemithi eminingi yengcindezi yegazi, kufaka phakathi i-ACE inhibitors, i-angiotensin receptor blockers, i-beta blockers kanye ne-diuretics. Zombili lezi zidakamizwa zibuye zihlanganyele nezigaba eziningana zemithi elwa nokudangala, okungenzeka kubangele ukopha (okungasongela impilo), kanye ne-sodium ephansi. Xhumana nochwepheshe wezokunakekelwa kwempilo ukuthola uhlu olugcwele lokusebenzisana kwezidakamizwa.
| Izidakamizwa | Isigaba Sezidakamizwa | I-Naproxen | Ibuprofen |
| I-Coumadin (warfarin) | I-Anticoagulant / igazi elincanyana | Yebo | Yebo |
| I-Aspirin Amanye ama-NSAID | Ama-NSAID | Yebo | Yebo |
| I-Zestril (lisinopril) I-Vasotec (enalapril) | Ama-ACE inhibitors | Yebo | Yebo |
| I-Cozaar (losartan) I-Avapro (irbesartan) I-Benicar (olmesartan) I-Diovan (valsartan) | I-ARB (i-angiotensin receptor blockers) | Yebo | Yebo |
| Lopressor I-Toprol XL (metoprolol) I-Tenormin (atenolol) | Abavimbela i-Beta | Yebo | Yebo |
| I-Lasix (furosemide) I-Hydrochlorothiazide | Izidakamizwa | Yebo | Yebo |
| I-Lexapro (escitalopram) I-Celexa (citalopram) I-Paxil (paroxetine) I-Prozac (fluoxetine) I-Zoloft (sertraline) | I-SSRI (i-serotonin reuptake inhibitors ekhethiwe) | Yebo | Yebo |
| U-Elavil (amitriptyline) I-Pamelor (nortriptyline) | I-Tricyclic antidepressants | Yebo | Yebo |
| I-Effexor (venlafaxine) I-Pristiq (desvenlafaxine) ICymbalta (duloxetine) | I-SNRI (i-serotonin ne-norepinephrine reuptake inhibitors) | Yebo | Yebo |
| I-Lanoxin (digoxin) | I-glycoside yenhliziyo | Yebo | Yebo |
| ILithium | Umenzeli we-Antimanic | Yebo | Yebo |
| IMethotrexate | I-Antimetabolite | Yebo | Yebo |
| ICyclosporine | I-Immunosuppressant | Yebo | Yebo |
| Ama-Antacids | Ama-Antacids | Yebo | Yebo |
| I-Carafate (sucralfate) | Umvikeli | Yebo | Akunjalo |
| I-Questran (cholestyramine) | I-Bile acid sequestrant | Yebo | Yebo |
Izexwayiso ze-naproxen vs. ibuprofen
Ngoba zombili i-naproxen ne-ibuprofen zingama-NSAID, zinezixwayiso ezifanayo:
- Kukhona isexwayiso esibhokisi (isexwayiso esiqine njengoba kudingwa yi-FDA):
- Imicimbi ye-cardiovascular thrombotic , njenge isifo senhliziyo noma isifo sohlangothi , okungabulala, kungenzeka. Ingozi ingenzeka ekuqaleni kokwelashwa futhi yande ngokusetshenziswa isikhathi eside.
- Ukusetshenziswa kwe-naproxen noma ibuprofen kuyaphikiswa ekubekweni kokuhlinzwa kwe-CABG.
- Kukhona ingozi eyengeziwe yokuphuma kwegazi, isilonda, noma ukugcwala kwesisu noma amathumbu, okungaba yingozi. Lokhu kungenzeka noma nini futhi ngaphandle kwesixwayiso. Iziguli esezikhulile noma ezinomlando wesifo se-peptic ulcer kanye / noma ukuphuma kwe-GI zisengozini enkulu. Ngenxa yalezi zingcuphe, iziguli kufanele zisebenzise umthamo ophansi kakhulu isikhathi esifushane ngangokunokwenzeka.
- Ama-NSAID akufanele asetshenziswe ezigulini ezinomlando wangaphambili wokuphendula okweqile, njenge-asthma, i-rash, noma i-anaphylaxis, ngenxa yengozi yokuphendulwa kwe-anaphylactic eqinile, engaba yingozi kulezi ziguli.
- Iziguli akufanele ziphathwe ngama-NSAID ngemuva kokuhlaselwa yinhliziyo.
- Kukhona ingozi encane yobuthi esibindini; iziguli kufanele zazi izimpawu ezifana nesicanucanu, ukukhathala, ukucobeka, isifo sohudo, ukulunywa, i-jaundice, ubumnene bangaphezulu kwesokudla, kanye nezimpawu ezinjengomkhuhlane, futhi zifune ukwelashwa okuphuthumayo uma kuvela izimpawu.
- Umfutho wegazi ophakeme (umfutho wegazi ophakeme) kungenzeka noma ukhule kakhulu.
- Ama-NSAID akufanele asetshenziswe ezigulini ezinokwehluleka kwenhliziyo.
- Ukusetshenziswa kwesikhathi eside kungadala ukulimala kwezinso. Iziguli kufanele zihlolwe ukusebenza kwezinso futhi akufanele zisebenzise ama-NSAID uma kunomsebenzi wezinso okhubazekile.
- Iziguli ezine-asthma, i-nasal polyps, ne-aspirin sensitivity (i-aspirin-sensitive asthma) kufanele igweme ama-NSAID.
- Ukusabela okunamandla kwesikhumba, okungafaka phakathi i-exfoliative dermatitis, iStevens-Johnson Syndrome (SJS), ne-epidermal necrolysis (TEN) m enobuthi engabulala futhi yenzeke ngaphandle kwesixwayiso. Iziguli kufanele ziyeke i-NSAID futhi zifune ukwelashwa uma kunophawu lokuphendula kwesikhumba.
- I-anemia yenzekile ezigulini ezelashwa ngama-NSAID; iziguli kufanele ziqashwe uma kwenzeka izimpawu noma izimpawu ze-anemia.
- Ama-NSAID, ngokunciphisa ukuvuvukala nomkhuhlane, angenza kube nzima kakhulu ukuthola izifo.
- Iziguli kuma-NSAID wesikhathi eside kufanele zihlolwe ngezikhathi ezithile nge-CBC kanye nephrofayili ye-chem.
- Ama-NSAID akufanele asetshenziswe kwabesifazane abakhulelwe kusukela ekuqaleni kokukhulelwa kwamasonto angama-30 (i-trimester yesithathu) ngoba kungadala ukuvalwa ngaphambi kwesikhathi kwe-fetus ductus arteriosus. Kuwo wonke ama-trimester wokuqala nowesibili, thintana nomhlinzeki wakho wezokunakekelwa kwempilo. Ama-NSAID nawo angaphazamisa ukuvuthwa kweqanda; thintana nomhlinzeki wakho wezokunakekelwa kwezempilo uma uzama ukukhulelwa.
Imibuzo ebuzwa njalo mayelana ne-naproxen vs. ibuprofen
Yini i-naproxen?
INaproxen iyi-NSAID (umuthi ongahambisani nokuvuvukala) osetshenziselwa ukwelapha ubuhlungu nokuvuvukala. Itholakala kuzo zombili izinhlobo zomkhiqizo kanye nezejenerikhi, nemithi kadokotela kanye ne-OTC.
Kuyini ibuprofen?
I-Ibuprofen futhi iyi-NSAID elapha ubuhlungu obumaphakathi kuya kokulingene nokuvuvukala. Itholakala kuzo zombili izinhlobo zomkhiqizo kanye ne-generic ngomuthi kadokotela noma njenge-OTC.
Ngabe i-naproxen ne-ibuprofen ziyefana?
Zombili lezi zidakamizwa zingama-NSAID avunyelwe yi-FDA. Ngoba womabili angama-NSAID, i-naproxen ne-ibuprofen anokufana okuningi kodwa futhi anokuhluka okuthile. Bona ngenhla ukuthola imininingwane. Amanye ama-NSAID afaka phakathi UCelebrex (celecoxib, i-COX-2 inhibitor), I-Mobic (meloxicam), i-aspirin, ne-Relafen (nabumetone). I-Tylenol (i-acetaminophen) akuyona i-NSAID kepha ivame ukutholakala eduze kwama-NSAID eshalofini. I-Tylenol iyasiza kumkhuhlane kanye nobuhlungu kepha ayilaphi ukuvuvukala.
Ngabe i-naproxen vs. ibuprofen ingcono?
Njengoba kushiwo ngenhla, i-naproxen ne-ibuprofen ziyefana futhi zombili zingasebenza ekunciphiseni ubuhlungu nokuvuvukala. Banemiphumela emibi efanayo nezingozi. Imvamisa, kuyindaba yokuzikhethela komuntu ukuthi yimuphi ongaba umuthi ongcono kuwe. Xhumana nomhlinzeki wakho wezokunakekelwa kwempilo ukuthola isiqondiso.
Ngingayisebenzisa i-naproxen vs. ibuprofen ngenkathi ngikhulelwe?
I-Naproxen, ibuprofen, noma i-NSAID akufanele isetshenziswe ku-trimester yesithathu yokukhulelwa ngoba ingadala ukuvalwa ngaphambi kwesikhathi kwe-fetal ductus arteriosus. Ngoba alukho ulwazi olwanele mayelana nokusetshenziswa kwe-NSAID kwabesifazane phakathi kwezinye izigaba zokukhulelwa, thintana ne-OB / GYN yakho. Uma njengamanje usebenzisa i-naproxen noma ibuprofen futhi uthola ukuthi ukhulelwe, thintana nodokotela wakho ukuze akuqondise.
Ngingayisebenzisa i-naproxen vs. ibuprofen ngotshwala?
Cha. Ukuthatha i-naproxen noma i-ibuprofen nokuphuza utshwala kungakhuphula kakhulu amathuba okuba nesifo sokuqaqamba kwesisu (ukuvuvukala kolwelwesi oluvikelayo lwesisu) nokopha emathunjini.
Kwenzekani uma uthatha i-naproxen ne-ibuprofen ndawonye?
Ungathathi i-naproxen ne-ibuprofen ndawonye. Hlola amalebula akho; okungcono, cela usokhemisi wakho, ikakhulukazi ngemikhiqizo ehlanganisiwe, ukuqinisekisa ukuthi uthatha i-NSAID eyodwa ngasikhathi sinye. Ukuthatha zombili kungakhuphula ubungozi bemiphumela emibi kanye nokopha esiswini kanye nezilonda.
Ingabe i-naproxen i-relaxer yemisipha noma i-pain killer?
I-Naproxen akuyona i-relaxer yemisipha ngokusemthethweni; kungumuthi wezinhlungu futhi usiza nokuvuvukala. Amanye ama-relaxer emisipha athandwayo afaka i-Flexeril (cyclobenzaprine) noma i-Skelaxin (metaxalone). Kungadida ngoba yize i-naproxen empeleni ingeyona i-relaxer yemisipha, ingasiza ubuhlungu obumaphakathi nobulinganiselayo, ngakho-ke kwesinye isikhathi abantu bacabanga ukuthi kuyisithambisi semisipha.
