IKlonopin vs. Ativan: Umehluko, ukufana nokuthi yikuphi okungcono kuwe

Izidakamizwa Vs. Umngani

Ukubuka konke kwezidakamizwa nokwehluka okuyinhloko | Izimo zilashwa | Ukusebenza | Ukutholakala komshuwalense nokuqhathaniswa kwezindleko | Okuqhamuka uma udla imishanguzo | Ukusebenzisana kwezidakamizwa | Izexwayiso | Imibuzo evame ukubuzwa

I-Klonopin (i-clonazepam) ne-Ativan (i-lorazepam) yimithi emibili engaphatha ukuphazamiseka kokukhathazeka. Yomibili le mithi ihlukaniswa njenge-benzodiazepines esebenza ngokubophezela kuma-GABA receptors ebuchosheni. I-GABA (i-gamma-aminobutyric acid) iyi-neurotransmitter enkulu ebuchosheni enemiphumela yokuvimbela. Ngenkathi zombili lezi zidakamizwa zisebenza ngendlela efanayo, zinomehluko othile wokuthi zisetshenziswa kanjani.

Kokubili iKlonopin ne-Ativan kubhekwa njenge-benzodiazepines esebenza phakathi. Lokhu kusho ukuthi imiphumela yabo ingahlala isikhathi eside kunezidakamizwa ezifanayo.

Uyini umehluko omkhulu phakathi kweKlonopin vs. Ativan?

IKlonopin (Yini iKlonopin?) Igama lomkhiqizo le-clonazepam. Isetshenziselwa ukwelapha ukuphazamiseka kovalo nokuquleka. I-Klonopin ihlala emzimbeni isikhathi eside ngokwengeziwe nengxenye yempilo yamahora angama-30 kuye kwangama-40. Lokhu kusho ukuthi umuntu usengayizwa imiphumela ebambekayo yeKlonopin isikhashana ngemuva kokuthi isithathiwe.

I-Ativan (Yini i-Ativan?) Igama lomkhiqizo le-lorazepam. Ingasetshenziselwa ukwelapha ukukhathazeka nokuquleka. Ifomu lokujova lingasetshenziselwa i-anesthesia ngaphambi kwezinqubo ezithile. I-Ativan ine-half-life yamahora angama-20 asemzimbeni.

Umehluko omkhulu phakathi kweKlonopin vs. Ativan
	I-Klonopin	I-Ativan
Isigaba sezidakamizwa	I-Benzodiazepine	I-Benzodiazepine
Isimo somkhiqizo / ejwayelekile	Uhlobo olujwayelekile luyatholakala	Uhlobo olujwayelekile luyatholakala
Ngubani igama elijwayelekile? Ngubani igama lomkhiqizo?	Igama elijwayelekile: Clonazepam Igama lomkhiqizo: Klonopin	Igama elijwayelekile: Lorazepam Igama lomkhiqizo: Ativan
Izidakamizwa zingena ngaziphi izinhlobo?	Ithebhulethi yomlomo	Ithebhulethi yomlomo Ukujova
Uyini umthamo ojwayelekile?	0.25 mg kabili ngosuku kuye ngemiyalo kadokotela wakho	1 mg kabili ngosuku kuye ngemiyalo kadokotela wakho
Yelashwa isikhathi esingakanani?	Nsuku zonke kuye ngemiyalo kadokotela wakho	Nsuku zonke kuye ngemiyalo kadokotela wakho
Ubani ovame ukusebenzisa umuthi?	Inkinga yokwethuka: Abantu abadala abaneminyaka engu-18 nangaphezulu Ukuquleka: Abantu abadala noma izingane ezineminyaka eyishumi	Ukukhathazeka: Abantu abadala noma izingane ezineminyaka engu-12 nangaphezulu

Ufuna intengo engcono kakhulu kuKlonopin?

Bhalisela izexwayiso zentengo zeKlonopin bese uthola ukuthi intengo ishintsha nini!

Thola izexwayiso zentengo

Izimo eziphathwa yiKlonopin ne-Ativan

Kokubili iKlonopin ne-Ativan kuvunyelwe i-FDA ukwelapha ukuquleka. I-Klonopin ingelapha ukwelashwa kwe-akinetic ne-myoclonic kanye nalokho okuvela ku-Lennox-Gastaut syndrome. I-Ativan isetshenziselwa ukwelapha uhlobo olunzima lokudlikiza olubizwa nge-status epilepticus.

I-Klonopin inqunyelwe ukwelapha izimpawu zokukhathazeka nokuhlaselwa uvalo okuphindayo. I-Ativan isetshenziselwa ukwelapha ukukhathazeka noma ukukhathazeka okubangelwa ukucindezeleka. Zombili lezi zidakamizwa zingasetshenziswa ngaphandle kwelebula zezinye izinhlobo zokuphazamiseka kokukhathazeka njenge-phobia yomphakathi.

I-Ativan ivunyiwe yi-FDA ukwelapha ukuqwasha kanti abanye odokotela banquma ukuthi i-Klonopin off-label yezinkinga zokulala. Okunye ukusetshenziswa okungekho kwelebula kweKlonopin ne-Ativan kufaka phakathi ukwelapha ukuhoxiswa kotshwala nokuxakaniseka.

Isimo	I-Klonopin	I-Ativan
Ukuquleka	Yebo	Yebo
Ukukhathazeka	Yebo	Yebo
Ukuphazamiseka kovalo	Yebo	Ngaphandle kwelebula
Ukuqwasha	Ngaphandle kwelebula	Yebo
Izimpawu zokuhoxiswa kotshwala	Ngaphandle kwelebula	Ngaphandle kwelebula

Ingabe iKlonopin noma i-Ativan isebenza kangcono?

Ngokuvamile, womabili amaKlonopin ne-Ativan yimithi yokwelapha esebenzayo. Ngoba zifundelwe ezinye izinhloso, ukusebenza kwazo kungahluka ngokuya ngesimo esiphathwayo.

Phakathi ku ukutadisha okuningi , izithako ezisebenzayo eKlonopin (clonazepam) nase-Ativan (lorazepam) zitholwe zisebenza ngokulinganayo ekwelapheni ukuphazamiseka kokukhathazeka. Kwakungekho mehluko obalulekile otholakele phakathi kwalezi zidakamizwa lapho kubhekwa ukuthuthuka kokukhathazeka nezikolo zokulala. Kodwa-ke, ucwaningo luthole ukuthi kube nemiphumela engemihle embalwa nge-clonazepam (26.7% uma iqhathaniswa ne-43.9%).

Enye funda kuqhathaniswa nokusetshenziswa kwe-clonazepam ne-lorazepam ye-status epilepticus, uhlobo olunzima lokubanjwa. Yize i-lorazepam ivunyelwe futhi isetshenziselwa kabanzi isimo se-epilepticus, i-clonazepam yatholakala iyindlela ewusizo. IClonazepam kwesinye isikhathi isetshenziswa ngaphandle kwelebula ngale njongo.

Xhumana nodokotela wakho noma umhlinzeki wezokunakekelwa kwempilo ongakunikeza iseluleko esifanele sezokwelapha. Ngokuya ngomlando wakho wezokwelapha, enye inketho ingaba ngcono kunenye.

Ufuna intengo engcono ku-Ativan?

Bhalisela izexwayiso zentengo ye-Ativan bese uthola ukuthi intengo ishintsha nini!

Thola izexwayiso zentengo

Ukuqhathaniswa kanye nezindleko zokuqhathaniswa kweKlonopin vs. Ativan

IGeneric Klonopin ivame ukumbozwa yiMedicare nezinhlelo eziningi zomshuwalense. Izindleko ezijwayelekile zokuthengisa zeKlonopin cishe zingama- $ 241. Ngekhadi lesaphulelo le-SingleCare, ungonga ku-generic Klonopin bese ukhokha cishe u- $ 10.

IGeneric Ativan ivame ukumbozwa yiMedicare nezinhlelo eziningi zomshuwalense. Izindleko ezijwayelekile zokuthengisa ze-Ativan cishe zingama- $ 21. Ngekhadi lesaphulelo le-SingleCare, ungonga ku-generic Ativan bese ukhokha cishe u- $ 7.

Zama ikhadi lesaphulelo somuthi we-SingleCare

	I-Klonopin	I-Ativan
Ngokuvamile embozwe umshwalense?	Yebo	Yebo
Imbozwe ngokujwayelekile yi-Medicare?	Yebo	Yebo
Umthamo ojwayelekile	Amaphilisi ayi-1 mg (ukulethwa kwama-60)	Amaphilisi angu-0.5 mg (ukulethwa kwama-30)
I-Medicare copay ejwayelekile	Kuya ngecebo lakho lomshuwalense	Kuya ngecebo lakho lomshuwalense
Izindleko ze-SingleCare	$ 10	$ 7

Imiphumela emibi ejwayelekile yeKlonopin ne-Ativan

I-Klonopin ne-Ativan zinemiphumela emibi efanayo, ethinta kakhulu uhlelo lwezinzwa oluphakathi (CNS). Njengokucindezelwa kwe-CNS, le mithi ingadala ukozela, isiyezi, ukucabanga okungafanelekile noma inkumbulo, kanye nokungaqiniseki noma izinkinga ngokusebenzisana. Zombili lezi zidakamizwa zingadala noma zenze ukucindezeleka kube kubi kakhulu kwabanye abantu, ikakhulukazi labo abanokudangala okungalashwa.

	I-Klonopin	I-Ativan
Imiphumela emibi	Kusebenza?	Imvamisa	Kusebenza?	Imvamisa
Ukozela	Yebo	7%	Yebo	15.9%
Ukucindezeleka	Yebo	4%	Yebo	n / a
Isiyezi	Yebo	1%	Yebo	6.9%
Ukwesaba	Yebo	1%	Akunjalo	-
Ukuntuleka kokuxhumana	Yebo	1%	Yebo	3.4%
Ukungasebenzi kwengqondo	Yebo	1%	Yebo	n / a
Ubuthakathaka	Akunjalo	-	Yebo	4.2%

* Xhumana nomhlinzeki wakho wezokunakekelwa kwempilo ngemiphumela engemihle engaba khona.

Umthombo: DailyMed ( I-Klonopin ), IDailyMed ( I-Ativan )

Ukusebenzisana kwezidakamizwa kweKlonopin vs. Ativan

I-Klonopin ne-Ativan zingasebenzisana nezinye izidakamizwa ezidala imiphumela efanayo. Ukuthatha ama-narcotic noma ama-opioid nge-benzodiazepines kungakhuphula imiphumela emibi njengokuthamba, ukozela, futhi, ezimweni ezinzima, ukuphuza ukuphefumula, ikhoma nokufa.

I-Benzodiazepines ingasebenzisana nezinye izidakamizwa zokudangala ze-CNS ezinjenge-anticonvulsants, antidepressants, antipsychotic, anesthetics, barbiturates, nezinye izinto ezithomalalisayo. Ukusebenzisa le mithi ndawonye kungakhuphula imiphumela engemihle njengokuzela nokulala.

Ngoba iKlonopin ne-Ativan zicutshungulwa esibindini, kufanele zigwenywe noma zibhekwe nezinye izidakamizwa ezicutshungulwa ngendlela efanayo. Ama-enzyme inhibitor afaka phakathi i-erythromycin, ketoconazole, ne-ritonavir engakhuphula izinga lama-benzodiazepines emzimbeni futhi ikhuphule nemiphumela engemihle yawo. Izidakamizwa ze-enzyme yesibindi zifaka i-carbamazepine ne-phenytoin enganciphisa izinga le-benzodiazepines emzimbeni.

Izidakamizwa	Isigaba Sezidakamizwa	I-Klonopin	I-Ativan
ICodeine I-Oxycodone I-Hydrocodone I-Morphine I-Methadone	Ama-opioid	Yebo	Yebo
Phenytoin ICarbamazepine I-Lamotrigine I-Valproic acid	Ama-anticonvulsants	Yebo	Yebo
I-Phenobarbital IPentobarbital Isebitalbital	Ama-barbiturates	Yebo	Yebo
I-Haloperidol Olanzapine I-Risperidone	Ama-antipsychotic	Yebo	Yebo
Amitriptyline I-Desipramine I-Doxepin I-Nortriptyline	I-Tricyclic antidepressants	Yebo	Yebo
I-Rasagiline Isocarboxazid I-Phenelzine USelegiline I-Tranylcypromine	I-Monoamine oxidase inhibitor (MAOI)	Yebo	Yebo
I-Probenecid	I-Uricosuric	Yebo	Yebo
Theophylline I-Aminophylline	I-Methylxanthine	Yebo	Yebo
I-Erythromycin I-Clarithromycin I-Telithromycin I-Rifampin	Imithi elwa namagciwane	Yebo	Yebo
Ketoconazole I-Itraconazole	Umenzeli we-antifungal	Yebo	Yebo

* Lokhu kungenzeka kungabi uhlu oluphelele lwako konke ukuhlangana kwezidakamizwa okungenzeka. Xhumana nodokotela ngayo yonke imithi okungenzeka uyayiphuza.

Izexwayiso zeKlonopin ne-Ativan

Ukuthatha i-Benzodiazepines nama-opioid ndawonye kufanele kugwenywe. Ukwenza kanjalo kungadala ubungozi obukhulu bokucindezeleka kokuphefumula, ikhoma nokufa.

I-Benzodiazepines ibhekwa njengezidakamizwa zeSheduli IV yi-DEA. Ngamanye amagama, zinamathuba athile okuhlukunyezwa nokuncika. Ngakho-ke, kuvame ukuthi kunconyelwe ukusetshenziswa kwesikhashana kuphela.

I-Klonopin ne-Ativan kufanele zigwenywe kubantu asebekhulile noma kulabo abangaba sengozini yokuwa. Ngoba zombili lezi zidakamizwa zithinta isibindi, kufanele futhi zibhekwe kulabo abanesifo sesibindi.

I-Klonopin ne-Ativan zifakwe kuhlu Isigaba Sokukhulelwa D. Ngakho-ke, akufanele zithathwe ngesikhathi sokukhulelwa. Xhumana nodokotela mayelana nezinyathelo okufanele uzithathe ngenkathi uhlela ukukhulelwa. Kufanele futhi zigwenywe noma ziqashwe ngenkathi uncelisa.

Imibuzo ebuzwa njalo ngeKlonopin vs. Ativan

Kuyini iKlonopin?

I-Klonopin iyi-benzodiazepine esebenza phakathi. Igama elijwayelekile leKlonopin yi-clonazepam. Kuvunyelwe ukwelapha ukuquleka kanye nokuphazamiseka kovalo (kufaka phakathi i-agoraphobia). I-Klonopin idinga ukuhlolwa kwezokwelapha nemithi kadokotela.

Yini i-Ativan?

I-Ativan yigama lomkhiqizo elithi benzodiazepine elaziwa ngegama lalo elijwayelekile elithi lorazepam. Kuvunyelwe ukwelapha ukukhathazeka nezinhlobo ezithile zokuquleka. Njengesidakamizwa sohlelo IV, singaba namandla okuhlukunyezwa nokuncika ngokomzimba noma ngokwengqondo.

Ngabe iKlonopin ne-Ativan ziyafana?

I-Klonopin (clonazepam) ne-Ativan (lorazepam) zingama-benzodiazepines afanayo asebenza ngezindlela ezifanayo. Ngenkathi bobabili bengaphatha ukuphazamiseka kokukhathazeka nokuhlaselwa okuthile, banokuhluka ekusebenzeni kwabo isikhathi eside. I-Ativan nayo ingasetshenziswa njenge-premedication ye-anesthesia kanti i-Klonopin ayijwayele ukusetshenziselwa le nhloso.

Ngabe iKlonopin noma i-Ativan ingcono?

I-Klonopin ne-Ativan yomibili imishanguzo kadokotela esebenzayo yokwelapha izimo ezithile kubandakanya ukukhathazeka nokuphazamiseka kokubamba. Ngokuya ngomlando wakho wezokwelapha, ungahle unikezwe omunye komunye.

Ngingayisebenzisa yini iKlonopin noma i-Ativan ngenkathi ngikhulelwe?

I-Klonopin ne-Ativan azinconywa kwabesifazane abakhulelwe. Ukuthatha i-benzodiazepines ngenkathi ukhulelwe kungandisa ingozi yokukhubazeka kokuzalwa. Xhumana nodokotela ukuze ubone ukuthi izinzuzo zingase zibe ngaphezu kwezingozi yini.

Ngingayisebenzisa iKlonopin noma i-Ativan ngotshwala?

IKlonopin ne-Ativan akunconywa ngenkathi uphuza utshwala. Ukwenza kanjalo kungakhuphula ubungozi bokuzela nokuzilolonga. Ukuphuza utshwala nge-benzodiazepines nakho kungakhuphula ingozi yokweqisa ngokweqile, ukucindezeleka kokuphefumula, ikhoma nokufa.

Ngabe iKlonopin ingcono kune-Ativan?

I-Klonopin ingancanyelwa imiphumela yaso ehlala isikhathi eside ngokuya ngesimo esiphathwayo. I-Klonopin nayo ingakhethwa ngokuhlaselwa okuthile. Kuvunyelwe ukwelapha ukuqubuka kwe-akinetic ne-myoclonic kanti i-Ativan iyi-FDA evunyelwe ukwelapha isimo sokuwa.

Yini enamandla iXanax noma i-Ativan?

I-Xanax (alprazolam) ifakwa ngokushesha okukhulu kune-Ativan. Imiphumela evela kuXanax ingazwakala kungakapheli ihora eli-1 kuye kwayi-1.5 kanti imiphumela evela ku-Ativan ingathatha isikhashana. Kodwa-ke, i-Ativan ihlala emzimbeni isikhathi eside ngoba imuncwa futhi icutshungulwe kancane.

Iyiphi i-benzodiazepine enamandla kakhulu?

I-Benzodiazepines ingahle isebenzise okwehlukile. Ngakho-ke, i-benzodiazepine enamandla kunazo zonke incike ekutheni isetshenziselwani nokuthi ithathwa kanjani. IHalcion (triazolam) neVersed (midazolam) ngama-benzodiazepines asebenza okwesikhashana angasebenza ngokushesha.