I-Creatinine: Ukuhlolwa kwegazi, ububanzi obujwayelekile, nokuthi ungawanciphisa kanjani amazinga

Imfundo Yezempilo

Ukumayela lakho lamabili ntambama, noma ufaka amandla kusethi yesithathu ebhentshini, noma uhamba ngebhayisikili ekukhuphukeni ohambweni lwakho lansuku zonke. Uphefumula ngokushesha, futhi imisipha yakho iyasha. Umjuluko uvuza isilevu sakho. Ukushisa kuqhuma izihlathi zakho. Futhi uma usuqedile, akukho okuzwa kangcono kuneshawa efudumele, ingilazi ebandayo yamanzi, nesihlalo kusofa.

Njengabantu abaningi, uyazi kahle ukuthi ukuzivocavoca umzimba kuwenza kanjani umzimba wakho zizwe— ukuphefumula, umjuluko nokushisa. Ungase uchume ngakho. Kepha kunokunye okuningi okwenzekayo ngaphansi kobuso. Lapho imisipha yakho yehla ngesikhathi sokuzivocavoca, ikhula kancane, inyuse imisipha, kepha le nqubo futhi ikhipha imfucuza egazini lakho, ngokuyinhloko i-creatinine.

Yize kungaba yinto yokugcina ocabanga ngayo ngenkathi ubeka amamayela akho noma ushaya i-rep-max, amazinga akho e-creatinine egazi angaba yinkomba eyinhloko yokusebenza kwempilo yezinso nezinso zakho.

Yini i-creatinine?

Wonke umuntu unamazinga athile we-serum creatinine egazini lakhe. I-Creatinine ingumkhiqizo wemvelo wokusetshenziswa kwemisipha, okubangelwa ukonakala kwekhemikhali elibizwa ngokuthi i-creatine. I-Creatinine uqobo ayinayo umsebenzi othile womzimba-kumane kungumkhiqizo wemfucuza. Imane ihlale egazini ize ifinyelele ezinso, lapho ihlungwa khona futhi isuswe ngokuchama.

Ngakho-ke, umzimba wakho uyikhiqiza kanjani i-creatinine? Kuqala ngokudala, okuhlanganiswa ezinso, amanyikwe, nesibindi, bese kuthuthwa ngokugeleza kwegazi futhi kugcinwe emisipheni yakho yamathambo. Ngesikhathi sokuzikhandla, imisipha yakho iguqula i-creatine ibe ngamandla, esiza ekunciphiseni kwemisipha. Ngemuva kokufeza injongo yayo, i-creatine iba i-creatinine iphinde ingene egazini elisendleleni eya ezinso.

Noma i-creatinine ingazuzi (noma ilimaza) umzimba wakho, inani le-creatinine egazini lakho lingalinganiswa ukuhlola impilo yezinso zakho. Ngalesi sizathu, odokotela bavame ukusebenzisa ukuhlolwa kwe-creatinine — kanye nokunye ukuhlolwa kwelebhu, njengokuhlolwa kwegazi i-urea nitrogen (BUN) —ukuqapha isifo esingapheliyo sezinso (CKD) noma ukwehluleka kwezinso.

Lithini izinga elihle le-creatinine?

Ezimweni eziningi, uhla olujwayelekile lwe-serum creatinine (etholakala egazini) lomuntu onezinso ezinempilo U-0.9 kuye ku-1.3 mg nge-desilitha ngalinye labesilisa abadala kanye no-0.6 kuya ku-1.1 mg nge-desilitha ngalinye kwabesifazane abadala .

Kodwa-ke, kunokuhlukahluka okuningi uma kukhulunywa ngamazinga we-creatinine. Okuvamile kuyigama elithile elizithobayo. Ukwehla kwemisipha kudala i-creatinine, ngakho-ke ubukhulu bemisipha yakho nezinga lomsebenzi kungathonya inani egazini lakho. Ukukala ngokunembile amazinga e-creatinine egazi, udokotela uzoqala ahlole lezi zinto ezahlukahlukene ukuthola isisekelo, ngokusho kukaTaylor Graber, MD, ongudokotela obulala izinzwa nomsunguli we Ama-ASAP IVs . Ukuhlolwa kwezinga le-Creatinine kuqala ngokuthola isisekelo sabantu ukuze kuhlolwe ukuthi yimaphi 'amazinga ajwayelekile' okufanele abe, kusho uDkt. Graber. Lokhu kuya ngeminyaka, ubuhlanga, ubulili, nosayizi womzimba. Lapho lawa manani esejwayelekile, izinguquko ezisuka kuleli banga zingakhombisa ukungajwayelekile kwezinso.

Abahlinzeki bezempilo bathanda ukubheka amazinga e-creatinine ngezizathu ezahlukahlukene. Uma ngabe unesifo sezinso noma njengamanje unesifo sezinso, ukulimala kwezinso, isifo sikashukela, noma esinye isifo esithinta izinso zakho, noma uthatha umuthi ongathinta izinso zakho, umhlinzeki wakho wezokunakekelwa kwempilo angahle ahlele ukulinganiswa kwe-creatinine okujwayelekile ukuqapha umsebenzi wakho wezinso. Izindlela ezivame kakhulu zokuhlola ngegazi nomchamo.

Ukuhlolwa kwegazi

I-creatinine evela egazini lakho ibizwa nge-serum creatinine, futhi ingalinganiswa ngokuhlinzeka ukuhlolwa kwegazi okujwayelekile. Lapho ukusebenza kwezinso kukhubazeka, i-creatinine encane iyakwazi ukususwa, okuholela ezingeni eliphakeme le-creatinine egazini, kuchaza uDkt Graber. Ngenkathi lokhu kuhlolwa kungakutsheli ngqo ukuthi izinso zisebenza kahle kangakanani, zingalandelwa ngokuhamba kwesikhathi kube nezinguquko. Abahlinzeki bezempilo bangakusebenzisa lokhu ukuhlolwa kwegazi kwe-creatinine (kanye nezinto ezifana nobudala, ubulili, ubuhlanga, njll.) ukubala isilinganiso sakho se-glomerular filtration (GFR), esibalulekile ekutholeni ukwehluleka kwezinso noma isifo esingapheliyo sezinso.

Ukuhlolwa komchamo

Enye indlela ejwayelekile yokuhlola amazinga we-creatinine ngefayela le- Ukuqoqwa komchamo wamahora angama-24 . Kungani amahora angama-24? Ukuzivocavoca umzimba, ukudla kanye ne-hydration konke kungathinta i-creatinine, ngakho-ke amazinga akho angashintshashintsha usuku lonke. Ngakho-ke, umhlinzeki wakho wezokunakekelwa kwempilo uzodinga amasampula omchamo amaningi ukuze linganisa imvume yakho ye-creatinine ngempumelelo . Njengoba ungacabanga, lokhu kuhlolwa kuhilela ukuqoqa wonke umchamo wakho ngaphezu kwamahora angama-24, bese ukuletha kumhlinzeki wakho wezokunakekelwa kwempilo. Ngokuya ngemiphumela, umhlinzeki wakho wezokunakekelwa kwezempilo anganquma ukuthi izinso zakho zihluza kahle kangakanani i-creatinine emgodini we-urinary.

Abahlinzeki bezokunakekelwa kwempilo bazo-oda izivivinyo zombili ukuze babheke ngokuphelele ukusebenza kwezinso zakho ngokuqhathanisa i-GFR yakho (eGFR) elinganisiwe nenani lomchamo creatinine okhona. Uma udokotela wakho esola isifo sezinso noma ukulimala, angahle futhi ahlele ukuhlolwa kwegazi urea nitrogen (BUN) ukuqinisekisa ukutholakala kwabo. Lokhu kuhlolwa kukala inani le-urea nitrogen — olunye uhlobo lwemfucuza ehlungwa izinso — kusampula yegazi.

Kusho ukuthini amazinga we-creatinine angajwayelekile?

Ngakho-ke, uye kudokotela, wenza izivivinyo, futhi imiphumela iku: Unamazinga aphezulu e-creatinine. Manje? Isinyathelo sokuqala — ungethuki. I-creatinine ephakanyisiwe akusho ukuthi izinso zakho zikwehlele phansi. Noma yini engaphandle kwebanga elijwayelekile (u-0.9 kuye ku-1.3 mg nge-desilitha ngayinye yabesilisa abadala kanye no-0.6 kuya ku-1.1 mg nge-desilitha ngayinye yabesifazane abadala) kungadala ukuthi umhlinzeki wezokunakekelwa kwempilo aphenye ngokuqhubekayo, kepha akusho ukupela njalo ingozi.Izici eziningi zingathonya imiphumela yakho yokuhlolwa. Nazi ezimbalwa nje:

• Ukuvivinya umzimba okwandisiwe: Uke wakha ukukhahlela ukufaneleka? Ejimini nsuku zonke? Le spike ekuqhekekeni kwemisipha izokwandisa ukukhiqizwa kwe-creatinine.
• Ukusetshenziswa kwamaprotheni okwandisiwe: Inyama ephekiwe iqukethe i-creatinine, ngakho-ke uma uzitika nge-steak nenkukhu eyosiwe njalo ebusuku, ungabona amazinga aphezulu.
• Ukuvinjelwa kwe-Urinary tract: Uma ungakwazi ukuchama, umzimba wakho awukwazi ukuqeda i-creatinine, ngakho-ke amatshe ezinso nokunye ukuphazamiseka komchamo kuzoyivumela ukuthi ihlale egazini lakho.
• Imithi ethile: Kwesinye isikhathi, izidakamizwa zingaba yicala. I-trimethoprim elwa namagciwane (thola amakhuphoni e-trimethoprim | imininingwane ye-trimethoprim) ne-I-Cimetidine (thola amakhuphoni e-Cimetidine | Imininingwane ye-Cimetidine), umuthi wesilonda esiswini kanye nesilungulela, ingavimbela uketshezi lwe-creatinine . Kwesinye isikhathi, izidakamizwa ezingezona ukuvuvukala (ama-NSAID), ezinjenge-ibuprofen, nazo zingaba imbangela.
• Umfutho wegazi ophezulu: Ucwaningo luye lwabonisa ukuthi umfutho wegazi ophezulu, ukwehluleka kwenhliziyo, nezinye izimo zenhliziyo kungadala amazinga akhulayo e-creatinine.

Ngokufanayo, i-creatinine ephansi ayiyona ingozi ngaso sonke isikhathi. Kungaba ngumphumela wesisindo semisipha esiphansi (noma isifo semisipha esinjenge-muscular dystrophy), ukukhulelwa, ukudla okunamaprotheni amancane, noma izimo ezithile zesibindi.

Ngabe amazinga e-creatinine angashintsha ngokushesha?

Amaleveli we-Creatinine angashintsha ngokushesha, ngisho naphakathi nosuku lonke, yingakho abahlinzeki bezempilo bebaqapha isikhathi eside. Ukuhlolwa okukodwa kwegazi okubuyisa i-creatinine ephezulu egazini kungaba yi-fluke. Kodwa-ke, izivivinyo eziningana zilandelana ezibonisa amazinga aphakeme zingakhombisa isifo esingapheliyo sezinso. I-spike engazelelwe emazingeni e-creatinine ingaba uphawu oluyisixwayiso lokulimala kanzima kwezinso noma ezinye izimo, ngokuya ngezimpawu.

Yini ukuxhumana phakathi komdlavuza namazinga e-creatinine?

Amazinga angajwayelekile e-creatinine angakhombisa umdlavuza wezinso noma wendlala yesinye. Noma, i-creatinine ephezulu noma ephansi ngokwayo ayisho ukuthi unomdlavuza.

Ungawehlisa kanjani amazinga e-creatinine

Ukuthi umhlinzeki wakho wezokunakekelwa kwempilo uwaphatha kanjani amazinga akho angavamile e-creatinine kuncike ngokuphelele embangela. Izinguquko endleleni yokuphila kanye nokudla kungaba yindlela elula nephumelelayo yokwelapha amacala amancane. Kepha isifo esingapheliyo sezinso, ukulimala kwezinso, noma ukwehluleka kwezinso kudinga izinqubo eziqinile. Imithi yokulawula izimpawu, i-dialysis, noma ezimweni ezimbi kakhulu, ukufakelwa kwezinso kungadingeka. Nazi izindlela ezimbalwa ezingaba khona zokwehlisa amazinga we-creatinine:

Okufanele ngikwenze

• Hlala u-hydrated
• Nciphisa ukudla amaprotheni
• Nciphisa umsebenzi onamandla (kodwa unganqamuli ukuzivocavoca ngokuphelele!)
• Thola i-fiber eningi ekudleni kwakho (ikakhulukazi izithelo nemifino)

Yini okufanele uyigweme

• Izithako zokwengeza noma okunye izithasiselo zokuqina komzimba
• Ukudla okwenziwe nge-sodium ephezulu
• Ukubhema
• Ukuphuza ngokweqile

Amakhambi emvelo

• Izithasiselo ze-Chitosan kubonise umphumela omuhle empilweni yezinso
• USalvia umuthi wendabuko waseChina yesifo sezinso
• Itiye eliluhlaza noma ama-herbal teas-ikakhulukazi ama-nettle, i-chamomile, i-ginseng, ne-dandelion
• Isinamoni

Imithi

Ayikho imishanguzo enciphisa ngqo inani le-creatinine egazini lakho. Uma udokotela enquma ukuthi isifo sezinso sibanga amazinga angajwayelekile e-creatinine, angahle anikeze umuthi wokunciphisa izimpawu. Imithi kadokotela ifaka:

• I-Angiotensin-converting enzyme (ACE) inhibitors njenge ILotensin (benazepril) noCapoten ( bongiwe ) ukuze wehlisa umfutho wegazi ophakeme .
• Ama-Angiotensin II Receptor blockers (ama-ARB) njengeEdarbi(azilsartan) noTeveten (eprosartan) futhi welapha umfutho wegazi ophakeme futhi unganciphisa inani lamaprotheni emchameni wakho.
• Ama-Erythropoiesis-stimulating agents (ama-ESA) ukusiza ukwandisa isibalo sakho segazi elibomvu.
• I-Phosphate noma i-potassium binders ukusiza ukuqeda i-phosphate ne-potassium eyengeziwe izinso zakho ezingenakuyihlunga.

OKUhlobene : Imininingwane yeLotensin | Imininingwane yeCaptopril

Zama ikhadi lesaphulelo le-SingleCare

Ekugcineni, iseluleko sezokwelapha esingcono kakhulu sokwenza ngcono ukusebenza kwezinso siphila impilo engaguquguquki enempilo. UDkt. Graber uthi: Ukunciphisa ukudla okungenampilo okuphezulu kwizithako ezicutshungulwayo, ukwanda kokudla izithelo nemifino, ukuzivocavoca umzimba (imizuzu eyi-150 yokuqina okulingene noma imizuzu engama-75 yokuzivocavoca ngamandla ngamandla ngeviki), ukuhlala unamanzi, nokugcina isisindo somzimba ku uhla olunempilo (inkomba yomzimba engu-20 kuye ku-25) yizinto okufanele ugxile kuzo ngokuhamba kwesikhathi ukuze uqiniseke ukuthi unikeza umzimba amathuluzi awadingayo ukuze uphumelele.