Ungasetshenziswa kanjani umuthi wesifo sikashukela ukwelapha i-PCOS

Imininingwane Yezidakamizwa

I-Polycystic Ovary Syndrome (i-PCOS) iyi- ukuphazamiseka kwamahomoni lokho kuthinta cishe 5 million abesifazane e-United States. Izimpawu ze-PCOS ziyahlukahluka kuye ngomuntu, okungenza kube nzima ukukukhomba. Abesifazane abaningi bahlupheka buthule, baphila iminyaka bengatholakalanga.

Izinhlangano ezingenzi nzuzo kulo lonke elase-U.S. Zisebenza ukusabalalisa ukuqwashiswa ngezimpawu nangezindlela zokwelashwa ezitholakalayo — kusuka ekulawuleni ukuzalwa kuya emethformin. Kepha ihlala ingenye yezimo ezibucayi kakhulu, ezingagodliwe kahle, ezingatholakali kahle nezingakhokhelwa kakhulu ezithinta impilo yabesifazane, uthi Sasha Ottey, umqondisi omkhulu we-non-profit PCOS Challenge Inc.

Kungani abanye besifazane bethola i-PCOS, futhi ibathinta kanjani?

UDkt Felice Gersh , owathola umklomelo i-OB-GYN, uthi i-PCOS yisifo esijwayeleke kakhulu se-endocrine sabesifazane asebekhulile-kodwa-ke sithinta zonke izici zomzimba wowesifazane. Kuthinta yonke imisebenzi ye-metabolic kanye nazo zonke izici zomjikelezo wokuya esikhathini nokuzala. Izimpawu ezivamile kungafaka: akukho sikhathi, isikhathi esingajwayelekile, noma isikhathi esinzima; ubuhlungu be-pelvic; ukukhula kwezinwele okungeziwe ebusweni bakho, okwaziwa njenge-hirsutism; umqubuko; ukuzuza kwesisindo noma izinselelo ngokunciphisa umzimba; nezimagqabhagqabha zesikhumba esimnyama esinsunduNgokuvumelana ne I-EndrocrineWeb , abesifazane abane-PCOS bangaba nama-cysts angama-25 noma ngaphezulu ku-ovary eyodwa.

Kukhona ifayela le- izizathu ezahlukahlukene kungani owesifazane oseminyakeni yokuzala engathuthukisa i-PCOS, kepha ucwaningo lukhombisa ukuthi ufuzo, ukumelana ne-insulin, kanye ne-androgen ngokweqile (okwaziwa nangokuthi ama-hormone abesilisa) yizo zonke izinto ezingaba yingozi.

I-PCOS ithinta abesifazane abavela ezizindeni ezahlukahlukene. Abesifazane bazo zonke izinhlanga nezinhlanga basengozini ye-PCOS, kusho UDkt Kate Killoran i-OB-GYN eMaine. Abesifazane nabesifazane abakhuluphele abanomlando womndeni kungenzeka bathinteke.

Yikuphi ukwelashwa kwe-PCOS?

Ngenkathi lungekho ikhambi le-PCOS, kunezindlela zokuphatha izimpawu. Uhlelo lokwelashwa lwesiguli ngasinye luzohluka kancane, ngokuya ngezimpawu zazo ezithile.

UDkt. Killoran uthi kunemithi embalwa engabekelwa iziguli ze-PCOS, kuya ngokuthi isimo sibathinta kanjani. Lolu akulona uhlu oluphelele, kepha lufaka:

• Ukulawulwa kokuzalwa kungasiza ukulawula ukungajwayelekile kokuya esikhathini.
• Izindlela zokuvimbela inzalo ngomlomo aqukethe i-estrogen kungasiza ukuthuthukisa izinduna.
• I-Metformin noma eminye imithi yokuthola ukuzwela kwe-insulin ingasiza ngokungajwayelekile komzimba futhi ithuthukise nokuzala.
• Letrozole kungadala i-ovulation lapho abesifazane abane-PCOS bezama ukukhulelwa.

Ukuguqulwa kwendlela yokuphila, ukuzivocavoca ngokukhethekile kanye nezinguquko zokudla okunomkhawulo wekhalori kungathuthukisa noma kuguqule i-PCOS, uDkt Killoran uyanezela.

Yini i-metformin eyenzela i-PCOS?

I-Metformin ngumuthi ojwayelekile osetshenziselwa ukwelapha izimpawu ze-PCOS. Yasungulwa ekuqaleni futhi imisiwe ukunakekelwa kohlobo lwesibili sikashukela, isifo se-metabolic esifana ne-PCOS, kusho UDkt Laurence Gerlis , udokotela ojwayelekile eLondon, eNgilandi.

Indima ye-metformin emzimbeni ukulawula ushukela wegazi ngokusiza umzimba ukuthi uphendule kangcono kwi-insulin eyenzayo ngokwemvelo, ukunciphisa inani likashukela elenziwa yisibindi, nokunciphisa inani likashukela amathumbu amunca ekudleni, ngokusho kokudla Ukuphathwa Kwezidakamizwa (i-FDA).

UDkt Gerlis uthi i-metformin ye-PCOS, lapho ithathwa njalo, izokwehlisa amazinga eglucose egazini ngokulinganisa amazinga e-insulin nokunciphisa eminye imiphumela yesimo somzimba.

Ingabe kukhona imiphumela emibi yokuthatha i-metformin ye-PCOS?

Kunezinkinga ezimbalwa kakhulu zokuphepha ezihlobene nokusetshenziswa njalo kwe-metformin, ngaphandle kokuxegiswa kwamathumbu, kusho uDkt Gerlis. Igesi, isifo sohudo, nobuhlungu besisu eminye yemiphumela emibi ejwayelekile ye-metformin.

UDkt Gersh, ngakolunye uhlangothi, akabeki ukuthi i-metformin ezigulini zakhe ngoba ibekwe njenge- ukuphazamiseka kwe-endocrine ngososayensi abathile bezemvelo. Yize kunempikiswano enkulu ebazungezile, abaphazamisi be-endocrine okusolwa ukuthi ahlobene ngomsebenzi wokuzala wokushintsha, umdlavuza webele, amaphethini wokukhula okungajwayelekile, nokuningi.

Ngingakanani i-metformin okufanele ngiyithathele i-PCOS? Kufanele kuthathwe isikhathi esingakanani i-metformin ye-PCOS?

Akukho ukuvumelana mayelana nomthamo ojwayelekile noma ubude be-metformin ye-PCOS; isilinganiso esiphakathi singu-1,500 mg nsuku zonke. Odokotela kaningi qala iziguli ku-500 mg nsuku zonke, futhi wandise umthamo kancane kancane ukunciphisa imiphumela emibi ye-metformin.

IMetformin itholakala ngemithi kadokotela kuphela, futhi yamukelwa yi-Food and Drug Administration (FDA) in 1994 e-United States. I-Metformin ithathwa ngomlomo, futhi kunjalo iyatholakala ngaphansi kwemikhiqizoFortamet, I-Glucophage , Amahlaya , noRiomet.

Njengoba i-metformin isungulwe kahle ngephrofayili enhle yezokuphepha, kunconywa kakhulu ukuthi uyiqale ekuqaleni kokuphathwa kwe-PCOS, uDkt Gerlis weluleka.

Ingabe i-metformin iyisiza kanjani i-PCOS nokulahlekelwa isisindo? Ngabe i-metformin isiza kanjani ngokungazali?

Ukwehla kwesisindo nokungazali, ukusebenza kwe-metformin akuyona ukusikwa okucacile.

UDkt. Killoran uthi iziguli ezine-PCOS ezingafuna ukuzama ukwelashwa kwe-metformin ukuphatha izimpawu zazo ngokuvamile zikhuluphele ngokweqile noma zikhuluphele futhi zizama ukukhulelwa, noma zizama ukuvimbela isifo se-metabolic, isifo senhliziyo nemithambo yegazi, noma isifo sikashukela esibi kakhulu.

Ngenkathi ukusetshenziswa kwe-metformin kuhlotshaniswa nokulahleka kwesisindo, imiphumela ayihambelani, usho kanjalo.

Ingabe zikhona ezinye izindlela zemvelo zemetformin ye-PCOS?

UDkt Gersh ukholelwa ukuthi indlela yokuqala yokubhekana ne-PCOS kungukushintsha indlela yokuphila nemikhuba emisha, njengokudla ukudla okutshalwa ezitshalweni, ukunciphisa ukucindezeleka, ukugxila ekulaleni, nokufaka ukuzivocavoca umzimba. Imithi yokwelashwa evame ukunconywa kakhulu ye-PCOS ithola izindlela zokukhuthala kakhulu nokudla ukudla okuphelele kakhulu.

Ezigulini zakhe, uDkt. Gersh uncoma izithako ezinhlobonhlobo zamavithamini, ngokuhlangana nezinguquko zokudla nokuvivinya umzimba ukwelapha izimpawu ze-PCOS. Isibonelo, i-vitamin B12 inganconywa ukuthi ithathwe noma ngemuva kokwelashwa kwe-metformin, njengoba i-malabsorption ye-vitamin B12 ingaba nomphumela we-metformin uma isetshenziswa isikhathi eside.

Khonamanjalo, uDkt. Killoran uthi i-PCOS inomthelela kumuntu ngamunye ngokuhlukile. Uthi kubalulekile ukwelapha i-PCOS noma ngabe izimpawu zesiguli azikhathazi, okwamanje. Bonke kufanele bazi ngobungozi babo bezinkinga zakamuva zezokwelapha ezifana nesifo se-metabolic kanye nesifo senhliziyo, uyeluleka. Isinqumo sokuphatha i-PCOS nokuthi yini okufanele isuselwe ekutheni ziyini izimpawu zowesifazane kodwa futhi nokunciphisa ubungozi.

Uma ucabangela i-metformin, hlela ukulandelela nodokotela wakho ukuze ubone okulungele wena.