Ingabe kufanele uthathe i-Wellbutrin ukuyeka ukubhema?

Imininingwane Yezidakamizwa

Ukubhema ugwayi kuyimbangela yalokhu Ukufa kwabantu abangama-480,000 ngonyaka e-US , ngokusho kwe-U.S. Centers for Disease Control and Prevention (CDC). Kubangela inqwaba yezinkinga zempilo, njenge-emphysema, isifuba somoya, ukutheleleka okuphezulu komoya, isifo senhliziyo, isifo esingapheliyo sokuvaleka kwamaphaphu (COPD), nomdlavuza wamaphaphu, umphimbo, noma umlomo — phakathi kwezinye. Yize ukusetshenziswa kukagwayi kube njalo kuncipha ngokuqhubekayo kusukela ekuqaleni kuka-2000 , Ngaphezu kwe 34.3 million Abantu abadala baseMelika basabhema.

Isizathu sokuthi abantu baqhubeke nokubhema ugwayi (yize kunemiphumela engemihle yezempilo) silula: ukulutheka. Kunzima kakhulu ukuyeka ukubhema — noma ngabe usebenzisa i-nicotine therapy noma umisa amakhaza. Kungenzeka ukuthi uzwile ngoNicorette noma uCantix ukusiza ngezimpawu zokuhoxa kodwa ekugcineni ngawukhahlela lo mkhuba I-Wellbutrin , obeye aziwe njengo bupropion , umuthi ojwayelekile owaziwa kancane osetshenziselwa ukuyeka ukubhema.

Yini i-Wellbutrin (bupropion)?

I-Bupropion —itholakala ngamagama ezimpawu i-Wellbutrin SR, i-Wellbutrin XL, ne-Zyban-iyi-antidepressant esetshenziselwa ukwelapha ukucindezeleka okukhulu kanye nokuphazamiseka kwonyaka. Odokotela babuye bakunikeze ukuyeka ukubhema, futhi bangabikho ilebula njengokwelashwa kwezimo zezokwelapha ezifana ne-ADHD.

I-Bupropion isebenza ngokuvimba ukumunca i-dopamine ebuchosheni bakho-okuholela emazingeni aphezulu, angakhuphula imizwa noma abe neminye imiphumela ezuzisayo, ngokusho kweNakia Eldridge, iFarm.D., Directory of Pharmacy Operations nge Isikhungo Sezokwelapha Somusa eBaltimore.

I-Dopamine iyi-neurotransmitter elawula uhlelo lokuvuza oluhambisana nokulutha kokubhema, kusho uDkt Eldridge. Kukholakala ukuthi i-dopamine isisusa sokuthola imivuzo yesikhathi esizayo. Ngokuvimba ukutholwa kabusha kwe-dopamine, kukholakala ukuthi i-bupropion inciphisa isignali yomvuzo eqhamuka ekubhemeni ugwayi.

UDkt. Eldridge uphawula ukuthi iWellbutrin neZyban banesithako esifanayo esisebenzayo, futhi bobabili bakhiqizwa yiGlaxoSmithKline (GSK). Ukwakheka kwabo kwehluke kancane, noma kunjalo. I-Zyban ifomu lokukhishwa okuqhubekayo kwe-bupropion emakethwa ngokukhethekile ukuyeka ukubhema. Inezinkomba ze-US Food and Drug Administration (FDA) zokucindezeleka okukhulu kanye nenkinga yokuphazamiseka kwenkathi ethile. I-Wellbutrin iyatholakala ekukhululweni okusheshayo kanye nakwindlela yokwandisa enwetshiwe. Kunezinkomba eziningi ze-FDA zeWellbutrin.

OKUhlobene : I-Wellbutrin ye-ADHD

Ufuna intengo engcono kuWellbutrin?

Bhalisela izexwayiso zentengo ye-Wellbutrin bese uthola ukuthi intengo ishintsha nini!

Thola izexwayiso zentengo

Ngabe i-Wellbutrin ingakusiza uyeke ukubhema?

Impendulo emfushane inguyebo, kepha kuya ngezici eziningi. Ucwaningo lwezemitholampilo lukhombisa ukuthi i-bupropion iyimithi ephumelelayo yokuyeka ukubhema futhi isiza abantu ukuthi bangahlali kusikilidi, ngokusho kukaKatie Taylor, Pharm.D., Usokhemisi omkhulu Gore & Inkampani .

Ezivivinyweni zomtholampilo, iziguli eziseZyban 300mg / ngosuku zazinezinga lokuyeka amasonto amane lamaphesenti angama-36, amaphesenti angama-25 ngeviki le-12, namaphesenti ayi-19 ngeviki lama-26, kusho uDkt Taylor. Lezi zinombolo zikhuphuke kakhulu uma iziguli zisebenzisa i-bupropion eceleni kwama-nicotine patches. Ngaphezu kwengxenye yalabo ababambe iqhaza bahlala ngaphandle kogwayi emavikini ayishumi.

Kukhona ukuhlolwa komtholampilo okuhleliwe njengamanje e-University of California Los Angeles (UCLA) ukuthola ukuthi ngabe i-Wellbutrin XL iyasebenza yini ngemithamo ephezulu yabantu abanezinkinga zempilo yengqondo abafuna ukuyeka ukubhema. UDkt Taylor ukholelwa ukuthi uWellbutrin angahle asebenze kangcono ekuyekeni ukubhema kubantu nabo abanokudangala, njengoba lokho kuyinkomba eyinhloko yezidakamizwa.

Njengoba uWellbutrin noZyban benesithako esifanayo esisebenzayo, uDkt. Eldridge uyachaza, akubanga khona ukufundwa kwekhanda phakathi kwamagama amabili womkhiqizo ukubona ukuthi yikuphi okusebenza kangcono.

Usebenzisa kanjani iWellbutrin ukuyeka ukubhema?

I-Wellbutrin isebenza kangcono kubantu ababhema osikilidi abayi-10 noma ngaphezulu ngosuku — uhhafu wepakethe noma ngaphezulu. Uma ukhetha ukusebenzisa i-bupropion ukuyeka ukubhema, udokotela wakho uzonquma isilinganiso esihle kakhulu. Itholakala kokulandelayo amafomu nezinketho zomthamo :

• Ithebhulethi yeBupropion hydrochloride, ukukhishwa ngokushesha: 75 mg, 100 mg
• Ithebhulethi yeBupropion hydrochloride, ukukhishwa okuqhubekayo kwehora eli-12: 100 mg, 150 mg, 200 mg
• Ithebhulethi yeBupropion hydrochloride, ukukhululwa okunwetshiwe kwehora lama-24: 150 mg, 300 mg, 450mg
• Ithebhulethi yeBupropion hydrobromide, ukukhishwa okunwetshiwe ihora lama-24: 174 mg, 348 mg, 522 mg

Uyithatha nsuku zonke, uqala isonto elilodwa kuya kwamabili ngaphambi kosuku lwakho lokuyeka. Lokhu kunikeza umuthi isikhathi sokwakha emzimbeni wakho, futhi kufinyelele ekusebenzeni okugcwele. Phakathi nala masonto okuqala, uyaqhubeka nokubhema.

Lapho usuku lwakho lokuyeka lufika, uyeka ukubhema ndawonye. Ungaqhubeka nokuthatha iWellbutrin izinyanga eziyisithupha kuya onyakeni ukukusiza uyeke ukubhema futhi uyeke unomphela.

Iyini imiphumela emibi yeWellbutrin?

Iningi leziguli alinayo le miphumela emibi. Imiphumela emibi ejwayelekile ye-bupropion ifaka:

• Isicanucanu
• Ukuqunjelwa
• Ukuhlanza
• Izifo
• Inkinga yokulala
• Ubuhlungu bemisipha noma bamalunga
• Amaphupho angajwayelekile
• Ukuphathwa ikhanda
• Umlomo owomile
• Isiyezi
• Izinguquko ekuziphatheni
• Ukuzuza kwesisindo noma ukunciphisa umzimba
• Ukushaya kancane

Ezimweni ezingavamile, le mithi ingaba nemiphumela emibi kakhulu njengobutha, imicabango yokuzibulala, ingozi yokuhlaselwa, noma ukushaya kwenhliziyo okungajwayelekile. Kukhona ingozi ephansi yezinkinga zenhliziyo, ikakhulukazi kubantu abane-high blood pressure noma isifo senhliziyo. Akufanele uthathe i-bupropion uma uthatha i-monoamine oxidase inhibitor (MAOI), ingaba nokuhlangana kwezidakamizwa okuyingozi. Akuvunyelwe kwiziguli ezine-bipolar disorder ngenxa yengozi eyengeziwe ye-mania.

Lolu akulona uhlu oluphelele lwemiphumela emibi. Kubalulekile ukuthi ukhulume nomhlinzeki wakho ukuthola ukuthi ngabe usengozini yanoma iyiphi yale miphumela emibi ngaphambi kokuqala noma imiphi imishanguzo kadokotela.

Yiziphi ezinye izidakamizwa ezitholakalayo zokuyeka ukubhema?

Ngaphambi kweminyaka yama-1980, okuwukuphela kwemithi yangempela etholakalayo yokuyeka ukubhema kwakuyizindlela zokwelapha ezingena esikhundleni se-nicotine ezahlukahlukene, kufaka phakathi:

• isichibi se-nicotine
• ushingamu we-nicotine
• i-nicotine inhaler
• izifutho zamakhala
• ama-lozenges

Le mithi isiza ekwehliseni izifiso nezimpawu zokuhoxa kwe-nicotine okuvame ukwenzeka ngemuva kokuba umuntu eyekile ukubhema. Manje kunezinketho eziningi.

Ngaphezu kukaWellbutrin noZyban, odokotela bangakhetha ukunikezela I-Chantix (varenicline) ezigulini ezifuna ukuyeka ukubhema. NgokukaDkt. Taylor, uChantix usebenza kuma-nicotine receptors ebuchosheni bakho futhi usiza ukunqanda izifiso.

Ikhadi lesaphulelo somuthi

Yimuphi umuthi okufanele ukhethe ukuyeka ukubhema ??

Ukukhethwa komuthi kuchaza isiguli kakhulu, kusho uDkt Taylor. Iningi leziguli lenza kahle ngemikhiqizo yokufaka esikhundleni se-nicotine futhi kunezinhlobonhlobo ongakhetha kuzo, ngakho-ke ukuthanda isiguli kungasilawula leso sinqumo. Indlela umuthi othinta ngayo umuntu ngamunye ingahluka.

Ukusebenza ngempumelelo

Ngempela, njengawo wonke ama-anti-depressants, lesi sidakamizwa singasebenza ngokuhlukile kusuka kwesiguli kuya kwesinye. I-Bupropion SR ingasiza isiguli esisodwa ukuyeka ukubhema ekuzameni kokuqala, kuyilapho kungenamthelela kwesinye.

Okuqhamuka uma udla imishanguzo

Ngokwengeziwe, iziguli zizobhekana nemiphumela engemihle ngokuhlukile. Imiphumela emibi ejwayelekile yeWellbutrin, iZyban, neChantix ziyefana kakhulu.

Izindleko nokutholakala komshuwalense

Kunamaphuzu entengo ehlukene okufanele awacabangele ngemithi yokuyeka ukubhema. Umshuwalense wakho ungabheka umuthi owodwa ngezinga elihlukile kunelinye. Imikhiqizo yokufaka esikhundleni seNicotine iyatholakala ekhawunteni, ngakho-ke izobiza amanani ahlukile kunalawo kadokotela.

Imikhuba yokubhema nezinye izimo zempilo

Isimo sengqondo sesiguli ngokuyeka ingase sibe yisici esibaluleke kakhulu, noma kunjalo. Imithi isebenza kangcono kubantu ababhemayo abahlela ukuyeka noma abazimisele ukuyeka, kusho uDkt. Eldridge. Ukwelashwa kufanele kube okwehlukile ukuze kubhekane nobunzima bokubhema nanoma yiziphi izifo ezivelele ezinjenge-acute coronary syndromes nesifo senhliziyo. Uyaphawula futhi ukuthi ucwaningo luye lwathola ukuthi izindlela zokwelapha ezihlanganisiwe, njengokusebenzisa i-bupropion hydrochloride noma i-varenicline kanye ne-nicotine replacement, zisebenza kakhulu kunanoma imuphi umuthi owodwa osetshenziswayo ngokwawo.

Konke lokhu kucatshangelwa kuvumelekile, futhi umuntu ngamunye kufanele azilinganisele yena futhi axoxe ngesinqumo nomhlinzeki wakhe wezokunakekelwa kwempilo.

Kufanele wena sebenzisa iWellbutrin ukuyeka ukubhema?

Unokukhetha okuningi okutholakalayo ukukusiza uyeke ukubhema. Ngakho-ke unganquma kanjani ukuthi i-Wellbutrin iyisinqumo esifanele kuwe?

Mhlawumbe ufuna ukuzama amakhambi emvelo ukuyeka ukubhema. Izindlela zokuziphatha ezingezona ezemithi zisebenzisa amasu okwelashwa ngokuziphatha kanye nezikhuthazo ezahlukahlukene ukushukumisa nokuqinisa izinguquko zokuziphatha, kusho uDkt. Eldridge. Inhloso yalokhu kungenelela ukuqinisa ukuzithiba ekubhemeni ngokuhlela imizamo yokuguqula indlela yokubhema. Ukuxoxisana noma ukwelulekwa okugqugquzelwayo kusiza ababhemayo ukuthi bahlole futhi baxazulule izimo zengqondo ezihlukile ngokuyeka ukubhema. Ezinye izindlela zifaka ukuzindla, i-hypnotherapy, i-yoga, i-acupuncture ne-tai chi.

Kwabanye abantu abakhetha ukugwema ukuthatha imishanguzo kadokotela, lezi zindlela ezingezona ezekhemisi zingakufanelekela ukuzihlola. Eqinisweni, noma ngabe uthatha i-Wellbutrin, kungakusiza ukuzama ezinye zalezi zincomo.

Nguwe nodokotela wakho kuphela eninganquma ukuthi iyiphi indlela yokuyeka ukuyeka okungcono kakhulu kuwe. Iseluleko esibaluleke kunazo zonke yilesi: Ungalokothi uyeke ukuzama ukuyeka. Ngizamile amahlandla ayisikhombisa ngaphambi kokuthi ngiphumelele. Ngakho-ke uma enye indlela yokuyeka ingakusebenzeli, zama enye. Zama ezimbalwa ngokuhlangana. Inhliziyo yakho namaphaphu akho kuzokubonga!