I-Effexor vs. Lexapro: Umehluko, ukufana, nokuthi yikuphi okungcono kuwe
Izidakamizwa Vs. UmnganiUkubuka konke kwezidakamizwa nokwehluka okuyinhloko | Izimo zilashwa | Ukusebenza | Ukutholakala komshuwalense nokuqhathaniswa kwezindleko | Okuqhamuka uma udla imishanguzo | Ukusebenzisana kwezidakamizwa | Izexwayiso | Imibuzo evame ukubuzwa
I-Effexor neLexapro yimithi emibili esetshenziswa ekwelapheni kokubili ukucindezeleka okukhulu (MDD) kanye nesifo sokukhathazeka esijwayelekile (GAD). Izimpawu zokucindezeleka zingabandakanya imizwa ephansi okungenani isikhathi esingamasonto amabili nokuphelelwa yintshisekelo emisebenzini ejwayelekile.
Ukukhathazeka okujwayelekile kubonakala ngokukhathazeka ngokweqile ngezinkinga ezahlukahlukene kufaka phakathi imali, impilo, umndeni, nomsebenzi owenzeka izinsuku eziningi kunangezinyanga eziyisithupha ezedlule. Kokubili MDD futhi GAD kuthinta izigidi zabantu baseMelika, futhi ukwelashwa okwanele kubalulekile kwikhwalithi yempilo. Ukwelashwa kokudangala noma ukukhathazeka kungabandakanya ukwanda komzimba, ukuzindla noma ukwelashwa kwengqondo. Ezinye izimo zizodinga imithi yokwelashwa okusebenzayo.
Uyini umehluko omkhulu phakathi kwe-Effexor neLexapro?
I-Effexor (venlafaxine) umuthi kadokotela okhonjisiwe ekwelapheni i-MDD ne-GAD. I-Effexor ingeyeqembu lama-anti-depressants eyaziwa njenge-serotonin-norepinephrine reuptake inhibitors ekhethiwe (SNRIs). I-Effexor ivimba ukuphinda kuthathwe kokubili i-norepinephrine ne-serotonin ku-synapse ye-neuron, kushiya ngempumelelo i-serotonin ne-norepinephrine yamahhala. Lawa ma-neurotransmitters adlala indima enhle kumood futhi athinte. Amanye ama-SNRI okungenzeka ujwayelene nawo yiCymbalta (duloxetine) nePristiq (desvenlafaxine).
I-Effexor (Yini i-Effexor?) Itholakala kumathebulethi akhishwa ngokushesha ngamandla ka-25 mg, 37.5 mg, 50 mg, 75 mg, no-100mg. Futhi iyatholakala kumathebulethi akhishwe ngokunwetshiwe nakuma-capsules ngamandla ka-37.5 mg, 75 mg, no-150 mg. Ithebhulethi ekhishwa enwetshiwe nayo iza ngamandla we-225 mg.
ILexapro (escitalopram) nayo iyimithi kadokotela ekhonjisiwe ekwelapheni i-MDD ne-GAD. ILexapro ingeyeqembu lama-anti-depressants eyaziwa ngokuthi i-serotonin reuptake inhibitors (SSRIs) ekhethiwe futhi isebenza ngokuvimba ukutholwa kabusha kwe-serotonin empompini wezokuthutha we-neuronal. Lesi senzo sishiya i-serotonin yamahhala kuma-neuron synapse, futhi amazinga aphezulu e-serotonin ahlotshaniswa nomoya ongcono. Amanye ama-SSRI ongawajwayela afaka phakathi i-Prozac (i-fluoxetine), i-Zoloft (i-sertraline), i-Celexa (i-citalopram), noma i-Paxil (i-paroxetine).
ILexapro (Yini iLexapro?) Iyatholakala njengethebhulethi yomlomo ngamandla we-5 mg, 10 mg, no-20 mg. Futhi iyatholakala njengesisombululo somlomo endaweni yokuhlushwa ye-5 mg / 5 ml.
| Umehluko omkhulu phakathi kwe-Effexor neLexapro | ||
|---|---|---|
| I-Effexor | I-Lexapro | |
| Isigaba sezidakamizwa | I-serotonin-norepinephrine reuptake inhibitor ekhethiwe | I-serotonin reuptake inhibitor ekhethiwe |
| Isimo somkhiqizo / ejwayelekile | I-Brand ne-generic iyatholakala | I-Brand ne-generic iyatholakala |
| Ngubani igama elijwayelekile? | I-Venlafaxine | I-Escitalopram |
| Izidakamizwa zingena ngaziphi izinhlobo? | Ithebhulethi, i-capsule ekhishwe isikhathi eside, namathebulethi | Isixazululo sethebhulethi nesomlomo |
| Uyini umthamo ojwayelekile? | 75 mg XR kanye ngosuku | 10 mg kanye ngosuku |
| Yelashwa isikhathi esingakanani? | Akupheli | Akupheli |
| Ubani ovame ukusebenzisa umuthi? | Intsha kanye nabantu abadala | Intsha kanye nabantu abadala |
Ufuna intengo engcono kakhulu kuLexapro?
Bhalisela izexwayiso zentengo yeLexapro bese uthola ukuthi intengo ishintsha nini!
Thola izexwayiso zentengo
Izimo eziphathwe yi-Effexor neLexapro
I-Effexor neLexapro zombili zikhonjisiwe ekwelapheni isifo esikhulu sokucindezeleka kanye nesifo sokukhathazeka esijwayelekile. I-Effexor futhi iphethe izinkomba zombili i-social phobia kanye ne-panic disorder. Kukhona nokusetshenziswa okungekho kwelebula kwezidakamizwa zombili. Ukusetshenziswa okungekho kwelebula kulapho kunqunywa khona umuthi kusetshenziswa inkomba engavunyelwe yi-Food and Drug Administration (FDA). I-Effexor isetshenziswe ngaphandle kwemvume ku-obsessive-compulsive disorder (OCD), premenstrual dysphoric disorder (PMDD), nokukhanya okushisayo okuhlobene nokunqamuka kokuya esikhathini. I-Lexapro kwesinye isikhathi isetshenziswa ngaphandle kwelebula ngezimo ezinjenge-OCD, i-bulimia nervosa, nokudla ngokweqile.
Ishadi elilandelayo linikeza uhlu lwezimo eziphathwe yi-Effexor neLexapro. Kungahle kungabandakanyi konke ukusetshenziswa okungaba khona, futhi kufanele uhlale uthintana nochwepheshe wakho wezokunakekelwa kwempilo ukuze ubone ukuthi ngabe enye yalezi zidakamizwa ikulungele yini.
| Isimo | I-Effexor | I-Lexapro |
| Ukucindezeleka okukhulu | Yebo | Yebo |
| Isifo sokukhathazeka esijwayelekile | Yebo | Yebo |
| Ukwesaba umphakathi | Yebo | Akunjalo |
| Ukuphazamiseka kovalo | Yebo | Ngaphandle kwelebula |
| Ukuphazamiseka okubangelwa ukucindezela | Ngaphandle kwelebula | Ngaphandle kwelebula |
| Ukuphazamiseka kwangaphambi kokuya esikhathini | Ngaphandle kwelebula | Ngaphandle kwelebula |
| Ukushisa okushisayo ngenxa yokunqamuka kokuya esikhathini | Ngaphandle kwelebula | Akunjalo |
| Bulimia amanosa | Akunjalo | Ngaphandle kwelebula |
| Ukudla ngokweqile | Akunjalo | Ngaphandle kwelebula |
| Ukucindezeleka kwangemva kwenhlekelele | Akunjalo | Ngaphandle kwelebula |
| Ukuphuma ngaphambi kwesikhathi | Akunjalo | Ngaphandle kwelebula |
Ingabe i-Effexor noma iLexapro isebenza kangcono?
TO ukuhlaziywa kwe-meta kuqhathaniswa i-Effexor, i-Lexapro, kanye nezinye izidakamizwa ezi-anti-depressant ezisuselwa ekusebenzeni nasekubekezeleleni kuzilingo ezingahleliwe eziyi-117 esikhathini esiyiminyaka eyi-16. Imiphumela ithole ukuthi bobabili u-Effexor noLexapro bebephumelela ngokufanayo ekwelapheni ukucindezeleka, futhi bobabili bebephumelela kakhulu kuneminye imithi eminingi elwa nokudangala. Kodwa-ke, iphrofayili yomphumela oseceleni we-Effexor ingenza kube nzima ukubekezelela kuneLexapro. Lokhu kungaholela kubabhali ukuthi bazame ukwelashwa ngeLexapro ngaphambi kokuzama i-Effexor.
Ukuqhathaniswa nokuqhathaniswa kwezindleko kwe-Effexor vs. Lexapro
I-Effexor imithi yokwelashwa kuphela evame ukumbozwa yizinhlelo zombili zomshuwalense wezohwebo kanye neMedicare. Inani elikhishwa ephaketheni lokuhlinzekwa kwezinsuku ezingama-30 le-Effexor XR 75 mg lingaba ngu- $ 146. Ngesigqebhezana se-Effexor esivela ku-SingleCare, ungathenga okujwayelekile cishe u- $ 15.
ILexapro futhi iyimithi kadokotela evame ukumbozwa yizinhlelo zombili zezentengiso nezeMedicare. Inani elikhishwa ephaketheni lokuhlinzekwa kwezinsuku ezingama-30 zeLexapro 10 mg lingabiza cishe ama- $ 200. I-SingleCare inikeza isigqebhezana se-Lexapro ejwayelekile, enganciphisa intengo ibe ngu- $ 15 emakhemisi abambe iqhaza.
| I-Effexor | I-Lexapro | |
| Ngokuvamile embozwe umshwalense? | Yebo | Yebo |
| Imbozwe ngokujwayelekile yi-Medicare Part D? | Yebo | Yebo |
| Umthamo ojwayelekile | 30, 75 mg XR amaphilisi | 30, 10 mg amaphilisi |
| I-Medicare copay ejwayelekile | Ngaphansi kuka- $ 10 | Ngaphansi kuka- $ 10 |
| Izindleko ze-SingleCare | $ 15 + | $ 15 + |
Thola isigqebhezana esivela kudokotela
Imiphumela emibi ejwayelekile ye-Effexor vs. Lexapro
I-Effexor neLexapro zombili zinemiphumela emibi engaba nomthelela ekulandeleni isiguli. Ngayinye yalezi zidakamizwa iyephuza ukuba nomthelela ezinkingeni eziyelaphayo, kwesinye isikhathi ithatha noma yikuphi kusuka emavikini amabili kuya kwayisithupha ukukhombisa umthelela ezimpawu. Iziguli zingahle zithole imiphumela emibi ngaphambi kokuthola ukuthethelelwa kwezimpawu zokuphazamiseka kwazo. Lokhu kungaholela ekutheni iziguli ziyeke ukwelashwa maduzane, futhi ukuphazamiseka kwazo kungalashwa. Kubalulekile ukuthi iziguli zazi imiphumela emibi engaba khona ngaphambi kokuqala ukwelashwa.
I-Effexor inomphumela ovelele kakhulu ekulaleni kuneLexapro. Cishe 18% weziguli kubike ukuqwasha, ukungakwazi ukulala nokulala, ngenkathi use-Effexor. Kuphela 4% ka- iziguli ubike lo mcimbi omubi noLexapro. Le mithi ingadala nokudinwa ngokweqile, noma ukozela ngokweqile. I-Effexor inamathuba amaningi okuthi ibangele ukudangala nge-7.5% yeziguli ezibika ukungahloniphi uma kuqhathaniswa ne-2% neLexapro. Ukulala kuthinta ikhwalithi yempilo futhi le miphumela emibi yinto ebaluleke kakhulu ngaphambi kokuqala ukwelashwa.
Imiphumela emibi yokugaya ukudla nayo ibikwe ngazo zombili izidakamizwa. I-Effexor inamathuba amaningi okudala izehlakalo zokucanuzela kwenhliziyo, uhudo, nokuqunjelwa kuneLexapro, yize le miphumela engemihle ingenzeka nganoma yisiphi isidakamizwa.
Ukwehla kwe-libido, noma idrayivu yezocansi, kungenzeka ukuthi ithinteke kabi yi-Effexor kuneLexapro. Kubalulekile ukuba nezingxoxo zempilo ezisezingeni neziguli ezibhekene nalomphumela ohlangothini.
Leli thebula alihloselwe ukuthi libe uhlu oluphelele lwemiphumela emibi engaba khona. Uyacelwa ukuthi ubonane nodokotela ukuze uthole uhlu oluphelele.
| I-Effexor | I-Lexapro | |||
| Umphumela oseceleni | Kusebenza? | Imvamisa | Kusebenza? | Imvamisa |
| Isicanucanu | Yebo | 11.8% | Yebo | 7% |
| Umlomo owomile | Yebo | 5.3% | Yebo | 5% |
| Ukujuluka | Yebo | 2.9% | Yebo | amaphesenti amabili |
| Uhudo | Yebo | 7.7% | Yebo | 5% |
| Ukuqunjelwa | Yebo | 3.4% | Yebo | 1% |
| Isiyezi | Yebo | 15.8% | Yebo | 3% |
| Ukuqwasha | Yebo | 17.8% | Yebo | 4% |
| Ukozela | Yebo | 7.5% | Yebo | amaphesenti amabili |
| Ukwanda komfutho wegazi | Yebo | 3.4% | Akunjalo | n / a |
| Ukwehla kwesifiso sokudla | Yebo | 9.8% | Yebo | 1% |
| Kwehlisiwe i-libido | Yebo | 5.1% | Yebo | 1% |
Umthombo: DailyMed ( I-Effexor I-DailyMed ( I-Lexapro )
Ukusebenzisana kwezidakamizwa kwe-Effexor vs. Lexapro
I-Effexor neLexapro umsebenzi ngamunye ngokwandisa i-serotonin etholakalayo. Lapho enye yalezi zidakamizwa ihlanganiswa nezinye izidakamizwa ezinomsebenzi we-serotonergic, kwandisa ithuba lokuthi isiguli singathola i-serotonin syndrome. I-Serotonin syndrome yisimo esidalwa ukuba ne-serotonin yamahhala kakhulu futhi ingaholela ekukhuphukeni kwengcindezi yegazi nokushaya kwenhliziyo, ukuyaluza, nesiyezi. Izidakamizwa ezinomsebenzi we-serotonergic zifaka umuthi wezinhlungu i-tramadol kanye nesengezo esivame ukusetshenziswa yiziguli zemizwa, iSt.John's Wort. Amanye amakilasi emithi angasebenzisana ngale ndlela futhi, ngakho-ke kubalulekile ukuthi udokotela wakho nosokhemisi babe nohlu oluphelele lwemithi oyiphuzayo.
I-Ondansetron, uma ithathwa ne-Effexor noma i-Lexapro, ingakhuphula izehlakalo zokwengezelwa kwe-QT nohlobo lwe-arrhythmia olwaziwa nge-torsades de pointes (TdP). Ngayinye yalezi zidakamizwa inengozi yale micimbi yenhliziyo, kepha ukusetshenziswa kwazo kuhlangene kwandisa ubungozi kakhulu. Le micimbi yenhliziyo ingaba yingozi kwezinye izimo, futhi ukuhlanganiswa kwalezi zidakamizwa ne-Ondansetron kufanele kugwenywe lapho kunokwenzeka.
Lokhu akuhloselwe ukuthi kube uhlu oluphelele lokuhlangana kwezidakamizwa okungenzeka. Xhumana nodokotela wakho noma usokhemisi ukuthola uhlu oluphelele.
| Izidakamizwa | Isigaba sezidakamizwa | I-Effexor | I-Lexapro |
| I-Almotriptan I-Eletriptan I-Oxitriptan | I-5HT Agonist / triptans (ama-antimigraine agents) | Akunjalo | Yebo |
| Usawoti we-Amphetamine I-Dexmethylphenidate I-Methylphenidate | Ama-Amphetamines | Yebo | Yebo |
| I-Ondansetron | Abaphikisi be-5HT3 (ama-anti-nausea agents) | Yebo | Yebo |
| I-Apixaban I-Edoxaban | Ama-antiplatelets | Yebo | Yebo |
| I-Aripiprazole | I-Antipsychotic | Yebo | Yebo |
| I-Aspirin Ibuprofen I-Naproxen I-Diclofenac | Izidakamizwa ezingezona ukuvuvukala (ama-NSAID) | Yebo | Yebo |
| IBemiparin Enoxaparin I-Heparin | Ama-anticoagulants | Yebo | Yebo |
| I-Buspirone | Ukukhathazeka ngokweqile | Yebo | Yebo |
| ICarbamazepine | I-Anticonvulsant | Akunjalo | Yebo |
| Esomeprazole Omeprazole | I-Proton pump inhibitor | Akunjalo | Yebo |
| I-Fluconazole | I-Antifungal | Yebo | Yebo |
| I-Fluoxetine I-Duloxetine I-Paroxetine Sertraline | Ama-SSRIs | Yebo | Yebo |
| I-Hydroxychloroquine | Aminoquinolone / I-Antimalarial | Yebo | Yebo |
| I-Linezolid | Imithi elwa namagciwane | Yebo | Yebo |
| I-Pimozide | I-Antipsychotic | Yebo | Yebo |
| USelegiline I-Phenelzine I-Rasagiline | I-Monoamine oxidase inhibitor (MAOI) | Yebo | Yebo |
| ISt. John's Wort | Ukwengeza ngamakhambi | Yebo | Yebo |
| I-Hydrochlorothiazide I-Chlorthalidone I-Metolazone | I-Thiazide isisu | Akunjalo | Yebo |
| I-Tramadol | Ukudambisa izinhlungu ze-opiate | Yebo | Yebo |
| Amitriptyline I-Clomipramine I-Doxepin I-Nortriptyline | I-Tricyclic antidepressants | Yebo | Yebo |
| I-Bupropion | I-Dopamine / norepinephrine reuptake inhibitor | Akunjalo | Yebo |
Izexwayiso ze-Effexor neLexapro
I-Effexor neLexapro zisetshenziselwa ukwelapha ukuphazamiseka kwempilo yengqondo njengokucindezeleka okukhulu nokukhathazeka okujwayelekile. Imiphumela ye-Effexor neLexapro ayenzeki ngokushesha. Kungathatha isikhathi esiphakathi kwamasonto amabili kuya kwayisithupha ukubona umthelela emithini. Kubalulekile ukuqonda ukuthi ukuthethelelwa kwezimpawu kungenzeka kungabi khona ngokushesha, futhi iziguli kufanele zikhuthazwe ukuthi zingayeki ukwelashwa ngaphandle kokubonisana nommeli wazo.
Iziguli ezinokucindezeleka zingathola ukwanda kwezimpawu noma imicabango yokuzibulala noma ngabe ziyayisebenzisa yini imishanguzo yokulwa nokudangala. Lezi zimo zingase zibe zimbi kuze kutholakale ukuxolelwa. Ukwelashwa kwe-Effexor neLexapro kungakhuphula umbono wokuzibulala nemicabango phakathi kwentsha nasebekhulile, ikakhulukazi ezigabeni zokuqala zokwelashwa ngaphambi kokuba kutholakale noma yiluphi uhlobo lokuxolelwa. Lezi ziguli kufanele zibhekwe ngeso elibukhali, futhi kungadingeka ushintsho uma kuvela izimpawu ngokuzumayo noma ziba zimbi kakhulu.
I-Serotonin syndrome ihlotshaniswa nokusetshenziswa kwe-Effexor, Lexapro, kanye neminye imithi efana ne-anti-depressant. Ihlotshaniswa ne-serotonin yamahhala kakhulu futhi ingadala ukukhuphuka kwenhliziyo, ukuyaluza, nesiyezi. Ubungozi be-serotonin syndrome buyanda lapho ezinye izidakamizwa ze-serotonergic zisetshenziswa ne-Effexor noma i-Lexapro.
I-Effexor neLexapro akumele imiswe ngokuzumayo noma ngaphandle kolwazi lommeli wakho. Ukuyeka le mithi ngokuzumayo kungaholela ezimpawu zokuhoxa ezinjengekhanda, isiyezi, ukukhathala nokucasuka.
Imibuzo ebuzwa njalo mayelana ne-Effexor vs. Lexapro
Kuyini i-Effexor?
I-Effexor umuthi kadokotela odambisa ukucindezelwa osetshenziswa ekwelapheni ukucindezeleka okukhulu kanye nenkinga yokukhathazeka ejwayelekile. Isebenza ngokwandisa i-serotonin yamahhala ne-norepinephrine. ILexapro itholakala kumathebulethi akhishwa ngokushesha futhi enwetshiwe, kanye namaphilisi akhishwa isikhathi eside.
Kuyini iLexapro?
I-Lexapro ngumuthi kadokotela odambisa ukucindezelwa osetshenziswa ekwelapheni ukucindezeleka okukhulu kanye nenkinga yokukhathazeka ejwayelekile. Isebenza ngokwandisa i-serotonin yamahhala. ILexapro iyatholakala njengethebhulethi yomlomo nesisombululo somlomo.
Ngabe i-Effexor neLexapro ziyefana?
Ngenkathi bobabili u-Effexor noLexapro belapha ukudangala nokukhathazeka, abafani. I-Effexor ivimba ukuphinda kuthathwe kokubili i-serotonin ne-norepinephrine ku-synapse ye-neuronal, kuyilapho iLexapro ivimba kuphela ukutholwa kabusha kwe-serotonin.
Ngabe i-Effexor noma iLexapro ingcono?
I-Effexor neLexapro zikhonjisiwe ukuthi zingaqhathaniswa nokusebenza ngempumelelo ekwelapheni ukucindezeleka, kodwa-ke, ucwaningo lukhombisa ukuthi iLexapro kungaba lula ukuyibekezelela. Iziguli eziseLexapro mancane amathuba okuthi ziyeke ukwelashwa kusenesikhathi.
Ngingayisebenzisa i-Effexor noma iLexapro ngikhulelwe?
Ukuphathwa Kwezokudla Nezidakamizwa (i-FDA) kubheka bobabili u-Effexor noLexapro njengabasesigabeni C sokukhulelwa, okusho ukuthi azikho izifundo zabantu ezanele zokunquma ukuphepha. Ukusetshenziswa kwale mithi kufanele kukhawulelwe ukusetshenziswa lapho izinzuzo zidlula ngokusobala izingozi. Kokubili i-Effexor neLexapro kufanele kugwenywe nakomama abancelisayo.
Ngingayisebenzisa i-Effexor noma iLexapro ngotshwala?
Utshwala bungakhuphula imiphumela emibi yomibili i-Effexor neLexapro. Ukuphuza utshwala ngenkathi uphuza le mithi kungadala ukukhubazeka okukhulu kwengqondo, futhi ngenxa yalesi sizathu, iziguli zelulekwa ukuthi zigweme utshwala uma zisebenzisa le mithi.
Ngabe i-Effexor iyona anti-depressant enhle kakhulu?
I-Effexor ikhonjiswe ukuthi iyasebenza ngendlela efanayo, uma ingaphezu kwalokho, kuneminye imithi elwa nokudangala. Kodwa-ke, kungaba nzima ukubekezelela iziguli. Udokotela wakho uzonquma ukuthi iyiphi indlela yokwelashwa ekufanele kakhulu.
Uyini umehluko phakathi kwe-Effexor ne-venlafaxine?
IVenlafaxine igama elejwayelekile le-Effexor, eliwumkhiqizo wegama lomkhiqizo. Imikhiqizo ye-venlafaxine ejwayelekile ithathwa njengengafakwa esikhundleni se-Effexor yi-FDA.
Ingabe i-venlafaxine iyakuthoba?
Ngenkathi ezinye iziguli zingahlangabezana nokudangala ngenkathi ziku-Effexor, kuyaziwa futhi ukuthi kubangele ukuthuthumela nokuzamazama kwezinye iziguli. Khuluma nodokotela wakho ukuthola ukuthi lo muthi ungakulungela yini.
Ingabe i-Effexor iyayithinta inkumbulo?
I-Amnesia ibikwe kwinani elincane leziguli ezithatha imikhiqizo ye-Effexor. Uma ubona lesi sehlakalo esingesihle, yazisa lowo obhalile ngaphambi kwakho ukuthi kungadingeka ushintsho kwezokwelapha.
