INabumetone vs. ibuprofen: Umehluko, ukufana, nokuthi yikuphi okungcono kuwe
Izidakamizwa Vs. UmnganiUkubuka konke kwezidakamizwa nokwehluka okuyinhloko | Izimo zilashwa | Ukusebenza | Ukutholakala komshuwalense nokuqhathaniswa kwezindleko | Okuqhamuka uma udla imishanguzo | Ukusebenzisana kwezidakamizwa | Izexwayiso | Imibuzo evame ukubuzwa
I-Nabumetone ne-ibuprofen yizidakamizwa ezingezona ukuvuvukala (ama-NSAID) ezisetshenziselwa ukwelapha ubuhlungu nokuvuvukala kwesifo samathambo. Kokubili i-nabumetone ne-ibuprofen yimithi ejwayelekile esebenza ngokuvimbela ukukhishwa kwe-prostaglandins, okuyizinto ezibangela ukuvuvukala nobuhlungu emzimbeni.
I-Ibuprofen ingaba igama lomndeni elijwayeleke kakhulu kune-nabumetone. Kodwa-ke, womabili ama-NSAID ayasebenza ekunciphiseni ubuhlungu nokuqina kwamalungu kulabo abane-osteoarthritis kanye nesifo samathambo. Qhubeka ufunde ukuze ufunde ngeminye umehluko obalulekile phakathi kwale mithi.
Uyini umehluko omkhulu phakathi kwe-nabumetone ne-ibuprofen?
INabumetone yigama elijwayelekile lokunqanyulwa manje, iRelafen. Itholakala ngemithi kadokotela futhi ngokuyinhloko isetshenziselwa ukwelapha ubuhlungu obuvela ku-osteoarthritis kanye nesifo samathambo. Amaphilisi ejwayelekile e-nabumetone ayatholakala ngamandla ka-500 mg kanye no-750 mg. Umthamo ojwayelekile we-nabumetone ufinyelela ku-2000 mg ngosuku othathwa njengomthamo kanye-nsuku zonke noma kabili-nsuku zonke.
I-Ibuprofen yaziwa ngamagama aziwa kakhulu njengo-Advil noMotrin. Ngokungafani ne-nabumetone, ibuprofen iyatholakala njengomuthi wokudambisa izinhlungu kadokotela noma we-over-the-counter (OTC). Ngenkathi ibuprofen ingalapha ubuhlungu besifo samathambo, ibuye ibhalwe ukuthi ukwelapha umkhuhlane, ubuhlungu bokuya esikhathini, nobuhlungu obuvela ekhanda noma emuva. I-Ibuprofen ivame ukuthathwa njalo emahoreni ayisithupha kuya kwayisishiyagalombili kuye ngamandla nokwakhiwa kwayo.
| Umehluko omkhulu phakathi kwe-nabumetone ne-ibuprofen | ||
|---|---|---|
| UNabumetone | Ibuprofen | |
| Isigaba sezidakamizwa | Isidakamizwa esingaqedi ukuvuvukala (i-NSAID) | Isidakamizwa esingaqedi ukuvuvukala (i-NSAID) |
| Isimo somkhiqizo / ejwayelekile | Okujwayelekile kuyatholakala; igama lomkhiqizo linqanyuliwe | I-Brand ne-generic iyatholakala |
| Ngubani igama lomkhiqizo? | Relafen | I-Advil, iMotrin, iMidol |
| Izidakamizwa zingena ngaziphi izinhlobo? | Ithebhulethi yomlomo | Ama-capsules omlomo Ithebhulethi yomlomo Uketshezi lomlomo Ukujova (NeoProfen) |
| Uyini umthamo ojwayelekile? | I-1000 kuya ku-2000 mg ngosuku ihlukaniswe ngemithamo eyodwa noma emibili | I-1200 kuya ku-3200 mg ngosuku ihlukaniswe ngemithamo emithathu noma emine |
| Yelashwa isikhathi esingakanani? | Isikhathi sokwelashwa sincike esimweni sempilo, ubunzima bezinhlungu, nezinye izinto. Ukwelashwa kungaba okwesikhashana noma isikhathi eside. | Isikhathi sokwelashwa sincike esimweni sempilo, ubunzima bezinhlungu, nezinye izinto. Ukwelashwa kungaba okwesikhashana noma isikhathi eside. Ifomu le-OTC le-ibuprofen akufanele lithathwe isikhathi eside kunezinsuku eziyi-10 ngaphandle kokubonisana nomhlinzeki wezokunakekelwa kwempilo. |
| Ubani ovame ukusebenzisa umuthi? | Abantu abadala | Abantu abadala nezingane izinyanga eziyisithupha nangaphezulu |
Izimo eziphathwe ngabumetone ne-ibuprofen
INabumetone ne-ibuprofen zombili zivunyelwe i-FDA ukwelapha ubuhlungu obumaphakathi kuya kokulingene nokuvuvukala okuvela i-osteoarthritis nesifo samathambo . I-osteoarthritis ne-rheumatoid arthritis yizimo ezingamahlalakhona ezithinta amalunga; Kodwa-ke, i-osteoarthritis ibonakala ngokuwohloka koqwanga oluzungeze amalunga ngokuhamba kwesikhathi kanti isifo samathambo siqala lapho amasosha omzimba ehlasela amalunga.
Njengama-NSAID, i-nabumetone ne-ibuprofen nakho kungaphatha ubuhlungu obumnene kuya kokulingene. Ngokuqondile, ama-NSAID angaphatha ikhanda, ubuhlungu be-musculoskeletal entanyeni, nobuhlungu obuphansi emuva. Ngenkathi ibuprofen i-FDA ivunyelwe ukwelapha izinhlungu, imfiva, nokuqaqamba kokuya esikhathini (i-dysmenorrhea eyinhloko), i-nabumetone ingasetshenziswa njengokwelashwa okungekho kwelebula.
| Isimo | UNabumetone | Ibuprofen |
| I-osteoarthritis | Yebo | Yebo |
| Isifo samathambo | Yebo | Yebo |
| Ubuhlungu | Ngaphandle kwelebula | Yebo |
| Imfiva | Ngaphandle kwelebula | Yebo |
| I-dysmenorrhea eyinhloko | Ngaphandle kwelebula | Yebo |
Ngabe i-nabumetone noma i-ibuprofen isebenza kangcono?
I-Nabumetone ne-ibuprofen kungukuqeda izinhlungu okusebenzayo kwe-NSAID uma isetshenziswa njengoba kushiwo. Zombili lezi zidakamizwa zivunyelwe i-FDA ukwelapha ubuhlungu nokuvuvukala kwesifo samathambo. I-NSAID ephumelela kakhulu iyona esebenza kangcono ngesimo nezimpawu zakho ezithile.
Esivivinyweni somtholampilo esilawulwa ngokungahleliwe, i-nabumetone yaqhathaniswa namanye ama-NSAID afana ne-ibuprofen, naproxen, ne-diclofenac ezigulini ezingaba ngu-4,000 ezine-osteoarthritis noma i-rheumatoid arthritis. Ngemuva Ukwelashwa amasonto ayi-12 , abacwaningi bathole ukuthi i-nabumetone yayisebenza ngokufana ne-ibuprofen namanye ama-NSAID lapho welapha i-osteoarthritis. Kodwa-ke, ucwaningo luthole ukuthi i-nabumetone ibisebenza kakhulu kunamanye ama-NSAID wesifo samathambo.
I-Nabumetone ngokuvamile ithatha isikhathi eside ukusebenza kune-ibuprofen namanye ama-NSAID. Imvamisa kuthatha cishe isonto elilodwa ukuthi i-nabumetone iqale ukusebenza futhi kuze kube amasonto amabili ukuthola impumuzo ephelele yezimpawu. Ngakolunye uhlangothi, ibuprofen iqala ukusebenza kungakapheli imizuzu engama-30 kuya ehoreni, noma ingadinga ukuthathwa kaningi ngosuku ukuthola impumuzo ephelele.
Xhumana nomhlinzeki wakho wezokunakekelwa kwezempilo ngeseluleko sokwelapha okungcono kakhulu kuwe. Umhlinzeki wakho wezokunakekelwa kwempilo angakunikeza imishanguzo yokuthenga noma yokuthenga ukuze usize ekwelapheni ubuhlungu bakho.
Ukuqhathaniswa kanye nezindleko zokuqhathaniswa kwe-nabumetone vs. ibuprofen
Iningi le-Medicare nezinhlelo zomshuwalense zizofaka i-nabumetone ejwayelekile. I-copay ye-nabumetone izoncika ohlelweni lomshuwalense kepha ingahle isuke ku- $ 0 iye ku- $ 57. Ngaphandle komshuwalense, intengo yemali emaphakathi ye-nabumetone icishe ibe $ 79.99. Ngekhuphoni le-SingleCare labumetone, ugcina ngentengo yezidakamizwa bese ukhokha cishe u- $ 19.
Izinhlelo eziningi zomshuwalense ngeke zimboze inguqulo ye-counter-the-counter ye-ibuprofen. Kodwa-ke, ngemithi kadokotela, iningi lama-Medicare nezinhlelo zomshuwalense zizomboza ibuprofen. Intengo emaphakathi yokuthengisa ye-ibuprofen icishe ibe ngama- $ 50 ngamaphilisi angama-30 kadokotela wamandla. Usebenzisa ikhadi lesigqebhezana le-SingleCare ibuprofen (imiyalo kadokotela iyadingeka) kungasiza ukwehlisa izindleko ze-ibuprofen.
| UNabumetone | Ibuprofen | |
| Ngokuvamile embozwe umshwalense? | Yebo | Yebo |
| Imbozwe ngokwejwayelekile yi-Medicare Part D? | Yebo | Yebo |
| Ubuningi | Amaphilisi angama-60, 500 mg | Amaphilisi angama-30, 800 mg |
| I-Medicare copay ejwayelekile | $ 0– $ 57 | $ 0– $ 22 |
| Izindleko ze-SingleCare | $ 19 + | $ 5 + |
Imiphumela emibi ejwayelekile ye-nabumetone vs. ibuprofen
INabumetone ne-ibuprofen kungadala imiphumela emibi efanayo. Imiphumela emibi ejwayelekile yalawa ma-NSAID yimiphumela emibi yamathumbu, njengokugaya ukudla, isifo sohudo nokuqunjelwa. Uma kuqhathaniswa ne-ibuprofen, i-nabumetone ingaba nethuba eliphakeme lokubangela ukugaya ukudla, ubuhlungu besisu, nohudo.
Eminye imiphumela emibi engaba khona ye-nabumetone ne-ibuprofen ifaka isicanucanu, isiyezi, ukuvuvukala ezandleni noma ezinyaweni (i-edema), ikhanda elibuhlungu, ukuqubuka kanye ne-tinnitus.
Imiphumela emibi ye-nabumetone ne-ibuprofen ingafaka umfutho wegazi ophakeme, izinkinga zezinso, isifo senhliziyo, unhlangothi , nezilonda zesisu noma zamathumbu. Ukungezwani komzimba nakho kungenzeka. Funa usizo lwezempilo ngokushesha uma uba nemiphumela emibi kakhulu noma imiphumela emibi eqhubeka noma eba mibi.
| UNabumetone | Ibuprofen | |||
| Umphumela oseceleni | Kusebenza? | Imvamisa | Kusebenza? | Imvamisa |
| Ukugaya ukudla | Yebo | 13% | Yebo | 1% –3% |
| Ubuhlungu besisu | Yebo | 12% | Yebo | 1% –3% |
| Uhudo | Yebo | 14% | Yebo | 1% –3% |
| Isicanucanu | Yebo | 3% –9% | Yebo | 1% –3% |
| Ukuqunjelwa | Yebo | 3% –9% | Yebo | 1% –3% |
| Isiyezi | Yebo | 3% –9% | Yebo | 1% –3% |
| I-Edema | Yebo | 3% –9% | Yebo | 1% –3% |
| Ubuhlungu bekhanda | Yebo | 3% –9% | Yebo | 1% –3% |
| I-Rash | Yebo | 3% –9% | Yebo | 1% –3% |
| Tinnitus | Yebo | 3% –9% | Yebo | 1% –3% |
Ukuvama akususelwa kudatha evela esivivinyweni sekhanda kuya ekhanda. Lokhu kungenzeka kungabi uhlu oluphelele lwemiphumela emibi engenzeka. Sicela ubheke udokotela wakho noma umhlinzeki wezokunakekelwa kwempilo ukuze ufunde kabanzi.
Umthombo: DailyMed ( UNabumetone ), IDailyMed ( Ibuprofen )
Ukusebenzisana kwezidakamizwa ze-nabumetone vs. ibuprofen
Ama-NSAID kufanele asetshenziswe ngokuqapha ngezidakamizwa ezinjenge-warfarin ne-aspirin. Ukuthatha ama-anticoagulants noma ama-antiplatelet drug nama-NSAID kungakhuphula ubungozi bokugaya amathumbu nezilonda.
Ama-NSAID anamandla okwandisa umfutho wegazi. Ngakho-ke, imiphumela yokwehlisa ingcindezi yegazi, njenge-lisinopril ne-losartan, ingahle yehliswe uma ama-NSAID nemishanguzo yegazi ithathwa ndawonye.
INabumetone ne-ibuprofen zinganciphisa imiphumela yemithi yokwelapha isisu. Umsebenzi wezinso ungadinga ukubhekwa ngenkathi uthatha ama-NSAID kanye ne-diuretics ndawonye.
Ukuthatha i-nabumetone noma i-ibuprofen nge-lithium noma i-methotrexate kungaholela kumazinga anqwabelene we-lithium noma i-methotrexate emzimbeni. Lokhu kungaholela kubuthi be-lithium noma i-methotrexate.
Lolu akulona uhlu oluphelele lokuhlangana kwezidakamizwa okungenzeka.
| Izidakamizwa | Isigaba sezidakamizwa | UNabumetone | Ibuprofen |
| I-Warfarin | I-Anticoagulant | Yebo | Yebo |
| I-Aspirin | I-Antiplatelet | Yebo | Yebo |
| I-Lisinopril I-Captopril URamipril | I-Angiotensin-converting enzyme (ACE) inhibitor | Yebo | Yebo |
| ILosartan Valsartan Olmesartan | I-Angiotensin receptor blocker (ARB) | Yebo | Yebo |
| UFurosemide I-Hydrochlorothiazide | Isisu | Yebo | Yebo |
| ILithium | Isimisi sokuqina | Yebo | Yebo |
| IMethotrexate I-Pemetrexed | I-Antimetabolite | Yebo | Yebo |
Thintana nochwepheshe wezokunakekelwa kwempilo mayelana nokunye ukuxhumana kwezidakamizwa okungenzeka.
Izexwayiso ze-nabumetone ne-ibuprofen
Izidakamizwa ezingezona ukuvuvukala (ama-NSAID) zingakhuphula ubungozi bezehlakalo zenhliziyo, njengokuhlaselwa yinhliziyo nokushaywa unhlangothi. Labo abanezifo zenhliziyo noma izici zobungozi besifo senhliziyo, njenge-high blood pressure noma i-cholesterol ephezulu, kufanele bagweme ama-NSAID noma bawasebenzise ngokuqapha.
Imithi efana ne-nabumetone ne-ibuprofen nayo ingakhuphula ubungozi bemicimbi yamathumbu, kufaka phakathi izilonda nokopha emathunjini. Iziguli esezikhulile nalabo abanomlando wezilonda esiswini kufanele bagweme ama-NSAID noma bawasebenzise ngokuqapha. Izimo zokopha kwamathumbu kungenzeka iphansi kancane nge-nabumetone kunokuba ne-ibuprofen.
Ama-NSAID angabangela ukugcinwa kwamanzi, noma i-edema, nokuwohloka kokuhluleka kwenhliziyo. Ukuqapha kufanele kwelulekwe ezigulini ezinomlando wokuhluleka kwenhliziyo.
Ukusetshenziswa kwesikhathi eside kwama-NSAID kungadala ukulimala ezinso ngokuhamba kwesikhathi. Xhumana nomhlinzeki wakho wezokunakekelwa kwezempilo uma unomlando wezinkinga zezinso ngaphambi kokusebenzisa ama-NSAID. Khuluma nodokotela wakho ngeminye imiphumela emibi engenzeka noma izehlakalo ezimbi ngaphambi kokusebenzisa ama-NSAID, njenge-nabumetone noma ibuprofen.
Imibuzo ebuzwa njalo mayelana ne-nabumetone vs. ibuprofen
Yini i-nabumetone?
INabumetone iyi-generic NSAID analgesic, noma i-reliever pain. Yigama elijwayelekile likaRelafen, futhi lingatholakala kuphela ngencwadi kadokotela. I-Nabumetone ivame ukuthathwa kanye noma kabili nsuku zonke njengethebhulethi yomlomo yokwelapha i-osteoarthritis ne-rheumatoid arthritis.
Kuyini ibuprofen?
I-Ibuprofen isebenza njenge-NSAID ukudambisa ubuhlungu nokuvuvukala okubangelwa i-osteoarthritis noma i-rheumatoid arthritis. Yize itholakala njengomuthi othengisa ngaphandle owelapha ubuhlungu nomkhuhlane, ingabekwa nasemandleni amakhulu okuphatha izinhlungu ezinzima kakhulu. Ibuprofen iza njengethebhulethi yomlomo, isixazululo soketshezi, i-capsule nomjovo. Amagama omkhiqizo we-ibuprofen afaka i-Advil neMotrin.
Ngabe i-nabumetone ne-ibuprofen ziyefana?
INabumetone ne-ibuprofen akufani. Yize bobabili beqeda izinhlungu ze-NSAID, i-nabumetone ne-ibuprofen zikalwa ngokungafani futhi zingaba nemiphumela ehluke kancane. INabumetone, edinga incwadi kadokotela, ingathathwa kanye nsuku zonke ngenkathi ibuprofen, etholakala ngaphezu kwekhawunta, imvamisa ithathwa izikhathi eziningi usuku lonke. Kokubili i-nabumetone ne-ibuprofen kungelapha ubuhlungu obungapheli isifo samathambo.
Ngabe i-nabumetone noma i-ibuprofen ingcono?
Uma kuqhathaniswa ne-placebo, noma akukho nhlobo ukwelashwa, i-nabumetone ne-ibuprofen zombili ziyasebenza ekwelapheni ubuhlungu nokuvuvukala kwesifo samathambo. INabumetone ingancanyelwa umthamo wayo kanye noma kabili-nsuku zonke. Kodwa-ke, i-nabumetone ingaba namandla okubangela ukugaya kakhulu kune-ibuprofen, futhi itholakala kuphela ngencwadi kadokotela. I-NSAID engcono iyindlela yokwelapha engabizi kakhulu kuwe njengoba kunqunywe ngosizo lukadokotela wakho.
Ngingasebenzisa i-nabumetone noma ibuprofen ngenkathi ngikhulelwe?
I-Nabumetone ne-ibuprofen, njengamanye ama-NSAID, kufanele kube njalo kugwenywe ngesikhathi sokukhulelwa sekwedlule isikhathi . Ukuthatha ama-NSAID ngesikhathi sokukhulelwa sekwephuzile kungakhuphula ubungozi bokukhubazeka nokuzalwa kwesisu. Xhumana nomhlinzeki wakho wezokunakekelwa kwezempilo uma uncelisa ngaphambi kokuthatha ama-NSAID.
Ngingasebenzisa i-nabumetone noma i-ibuprofen ngotshwala?
Ukuphuza utshwala ngokulinganisela ngenkathi uthatha i-nabumetone noma ibuprofen njengoba kunqunyiwe ngokuvamile kuphephile. Izinkinga zingaqala lapho ukusetshenziswa kwesikhathi eside kwe-NSAID kuhlangene nokusetshenziswa ngokweqile kotshwala. Ukuphuza njalo utshwala nama-NSAID kungaholela engcupheni eyengeziwe yezilonda zesisu, ukukhubazeka kwezinso, neminye imiphumela emibi.
Kuthatha isikhathi esingakanani ukuthi i-nabumetone isebenze?
Kungathatha isonto elilodwa ukuqala ukuzwa imiphumela ye-nabumetone. Kwezinye izimo, kungathatha amasonto amabili noma ngaphezulu ukuzwa ukukhululeka okuphezulu nge-nabumetone.
Ngabe i-nabumetone ifana ne-tramadol?
INabumetone yisidakamizwa esingaqedi ukuvuvukala ngenkathi i-tramadol iyi-opioid. I-Tramadol ibhekwa njengesidambisi esinamandla sokudambisa izinhlungu kune-nabumetone. Uma kuqhathaniswa ne-nabumetone, i-tramadol isetshenziselwa ukwelapha izinhlobo ezinzima kakhulu zobuhlungu.
Ngabe i-nabumetone ibangela ukuzuza kwesisindo?
I-Nabumetone ayijwayele ukudala ukukhuluphala komphumela ojwayelekile. Ukuzuza kwesisindo kusuka ku-nabumetone kungakhombisa ukugcinwa kwamanzi noma ukwanda kokuhluleka kwenhliziyo. Thintana nomhlinzeki wakho wezokunakekelwa kwempilo ngokushesha uma uthola ukukhuluphala okungavamile noma ukuvuvukala ezandleni noma ezinyaweni.
