I-Paxil vs.Zoloft: Umehluko, ukufana, futhi okungcono kuwe
Izidakamizwa Vs. UmnganiUkubuka konke kwezidakamizwa nokwehluka okuyinhloko | Izimo zilashwa | Ukusebenza | Ukutholakala komshuwalense nokuqhathaniswa kwezindleko | Okuqhamuka uma udla imishanguzo | Ukusebenzisana kwezidakamizwa | Izexwayiso | Imibuzo evame ukubuzwa
I-Paxil (paroxetine) kanye Zoloft (i-sertraline) ama-SSRI (ama-serotonin reuptake inhibitors akhethiwe) akhonjisiwe ekwelapheni ukucindezeleka nezinye izimo zengqondo. I-SSRI isebenza ngokwandisa amazinga e-serotonin ebuchosheni, okusiza ukuthuthukisa izimpawu. Yomibili imishanguzo kadokotela ivunywa yi-Food and Drug Administration (FDA). Eminye imithi ekilasini le-SSRI yile I-Prozac (i-fluoxetine), UCelexa (citalopram), futhi I-Lexapro (escitalopram). Yize iPaxil neZoloft zifana, zinokuhluka okuphawulekayo kuzinkomba zazo kanye nezindleko.
Uyini umehluko omkhulu phakathi kwePaxil neZoloft?
I-Paxil ne-Zoloft yi-SSRI (imithi ekhethiwe ye-serotonin reuptake inhibitor). Yomibili le mithi itholakala ngohlobo lomkhiqizo nangokwejwayelekile. Igama elijwayelekile likaPaxil ngu-paroxetine, kanti igama elijwayelekile likaZoloft yi-sertraline. Yize i-dosing iyahluka, umthamo ojwayelekile wePaxil ungama-20 mg nsuku zonke, kanti umthamo ojwayelekile weZoloft ungama-50 mg nsuku zonke. I-Paxil iyatholakala ngefomu lethebulethi, kanye namathebulethi akhululiwe, kanye nokumiswa. I-Zoloft itholakala kumathebulethi nakwisixazululo.
| Umehluko omkhulu phakathi kwePaxil neZoloft | ||
|---|---|---|
| I-Paxil | Zoloft | |
| Isigaba sezidakamizwa | I-serotonin reuptake inhibitor ekhethiwe (SSRI) | I-serotonin reuptake inhibitor ekhethiwe (SSRI) |
| Isimo somkhiqizo / ejwayelekile | Umkhiqizo nokujwayelekile | Umkhiqizo nokujwayelekile |
| Ngubani igama elijwayelekile? | I-Paroxetine | Sertraline |
| Yiziphi izinhlobo ezafika zomuthi? | Amathebulethi Amaphilisi wokukhishwa anwetshiwe Ukumiswa | Amathebulethi Isixazululo |
| Uyini umthamo ojwayelekile? | 10-60 mg nsuku zonke, kuya ngesibonakaliso nempendulo ekwelashweni | 50-200 mg nsuku zonke, kuya ngesibonakaliso nempendulo ekwelashweni |
| Yelashwa isikhathi esingakanani? | Isikhathi eside, kuya ngemiyalo kadokotela wakho | Isikhathi eside, kuya ngemiyalo kadokotela wakho |
| Ubani ovame ukusebenzisa umuthi? | Abantu abadala; off-ilebula ezinganeni ezineminyaka eyisikhombisa nangaphezulu | Abantu abadala, izingane ezineminyaka eyisithupha nangaphezulu |
Ufuna intengo engcono kakhulu ku-Paxil?
Bhalisela izexwayiso zentengo yePaxil bese uthola ukuthi intengo ishintsha nini!
Thola izexwayiso zentengo
Izimo eziphathwe yiPaxil kanye neZoloft
I-Paxil ne-Zoloft zombili zikhonjisiwe ngesifo sokucindezeleka okukhulu. I-Paxil iphinde ikhonjiswe ngesifo se-obsessive-compulsive, panic disorder, social anxiety disorder, kanye ne-panic disorder. Ngenkathi iZoloft ingakhonjisiwe ngalezi ezinye izimo, odokotela abaningi bayayinikeza ukuthi ingekho ilebula yokwelapha lezi zimo.
| Isimo | I-Paxil | Zoloft |
| Isifo esikhulu sokucindezeleka (MDD) | Yebo | Yebo |
| Isifo se-Obsessive-compulsive (OCD) | Yebo | Akunjalo |
| Ukuphazamiseka kovalo | Yebo | Akunjalo |
| Inkinga yokukhathazeka komphakathi | Yebo | Akunjalo |
| Isifo sokukhathazeka esijwayelekile | Yebo | Akunjalo |
Ngabe iPaxil noma iZoloft isebenza kangcono?
Ngokungahleliwe, okuyimpumputhe kabili funda ngokuqhathanisa le mithi emibili yokwelapha ukuphazamiseka kwesifo, iPaxil neZoloft kutholakale ukuthi zisebenza ngokulinganayo; kodwa-ke, uZoloft wayebekezeleleka kancane, futhi iziguli zenze kangcono lapho ziyeka lesi sidakamizwa.
Komunye okungahleliwe, ukutadisha okungaboni kabili yePaxil kanye neZoloft amasonto angama-24, yomibili le mithi yayisebenza ngendlela efanayo ekwenzeni ngcono izinga lokuphila kweziguli ezinenkinga enkulu yokudangala. I-Paxil ne-Zoloft nazo zibekezelelwe kahle, kanti iziguli ze-Zoloft zinemiphumela emibi embalwa.
Enye funda wabheka uPaxil noZoloft, kanye noProzac, ezigulini ezinengcindezi enkulu namazinga aphezulu okukhathazeka (ukukhathazeka ngokweqile) futhi zathola ukuthi yonke le mithi emithathu isebenza ngokufanayo futhi ibekezeleleka kahle.
Umuthi osebenza kahle kakhulu kuwe kufanele unqunywe kuphela ngumhlinzeki wakho wezokunakekelwa kwempilo ongacabangela izimo zakho zezokwelapha, umlando, neminye imithi oyiphuzayo engasebenzisana nePaxil noma iZoloft.
Ufuna intengo engcono kakhulu ku-Zoloft?
Bhalisela izexwayiso zentengo yeZoloft bese uthola ukuthi intengo ishintsha nini!
Thola izexwayiso zentengo
Ukuqhathaniswa kanye nezindleko zokuqhathaniswa kwePaxil neZoloft
I-Generic Paxil (i-paroxetine) ne-generic Zoloft (i-sertraline) ivame ukumbozwa ngaphansi kwemishwalense eminingi kanye ne-Medicare Part D. Ngaphandle komshwalense, ukunikezwa kwezinsuku ezingama-30 kwegama lomkhiqizo i-Paxil kuzobiza cishe ama- $ 25, kanye nokuhlinzekwa kwezinsuku ezingama-30 kweZoloft kubiza cishe u- $ 35. Ama-copays e-Insurance ne-Medicare Part D ayahluka ngohlelo. Ukukhetha izinhlobo ezijwayelekile zale mithi kuzokongela imali enkulu. Ungakhokha u- $ 4- $ 25 nge- paroxetine futhi cishe u- $ 7-17 we-sertraline hcl.
| I-Paxil | Zoloft | |
| Ngokuvamile embozwe umshwalense? | Yebo (okujwayelekile) | Yebo (okujwayelekile) |
| Imbozwe ngokwejwayelekile yi-Medicare Part D? | Yebo (okujwayelekile) | Yebo (okujwayelekile) |
| Umthamo ojwayelekile | # 30, 20 mg amaphilisi (ejwayelekile) | # 30, 50 mg amaphilisi (ejwayelekile) |
| Inkokhelo ejwayelekile yeMedicare Part D | $ 0-15 | $ 0-12 |
| Izindleko ze-SingleCare | $ 4-25 | $ 7-17 |
Imiphumela emibi ejwayelekile yePaxil neZoloft
Okuvame kakhulu imiphumela emibi of Paxil kukhona isicanucanu, ukozela, ikhanda, umlomo owomile, nokuba buthakathaka. Imiphumela emibi kakhulu ye-Zoloft iyisicanucanu, umlomo owomile, isifo sohudo nokuqwasha. Zombili lezi zidakamizwa zinohlu olufanayo lwemiphumela emibi, njengoba kuboniswe ngezansi, ngamaphesenti ahlukahlukene eziguli ezithola le miphumela emibi.
Xhumana nomhlinzeki wakho wezokunakekelwa kwempilo ukuthola uhlu oluphelele lwemiphumela emibi.
| I-Paxil | Zoloft | |||
| Imiphumela emibi | Kusebenza? | Imvamisa | Kusebenza? | Imvamisa |
| Ukozela | Yebo | 2. 3% | Yebo | 13% |
| Isicanucanu | Yebo | 26% | Yebo | 26% |
| Ubuhlungu bekhanda | Yebo | 18% | Yebo | amaphesenti amabili |
| Ubuthakathaka | Yebo | ishumi nanhlanu% | Yebo | % ayinikiwe |
| Ukujuluka | Yebo | ishumi nanye% | Yebo | 8% |
| Umlomo owomile | Yebo | 18% | Yebo | 16% |
| Ukuqunjelwa | Yebo | 14% | Yebo | 8% |
| Uhudo | Yebo | 12% | Yebo | 18% |
| Isiyezi | Yebo | 13% | Yebo | 12% |
| Ukuqwasha | Yebo | 13% | Yebo | 16% |
| Ukuthuthumela | Yebo | 8% | Yebo | ishumi nanye% |
| Ukwesaba | Yebo | 5% | Yebo | % ayinikiwe |
| Kwehlisiwe i-libido | Yebo | 3% | Yebo | 1% |
| Ukuphazamiseka kokuchama | Yebo | 13% | Yebo | 7% |
| Ukubona okufiphele | Yebo | 4% | Akunjalo | - |
Umthombo: I-DailyMed (Paxil) , I-DailyMed (Zoloft)
Ukusebenzisana kwezidakamizwa kwePaxil kuqhathaniswa neZoloft
Ama-MAO inhibitors (i-monoamine oxidase inhibitor antidepressants) ngokuhlangana ne-Paxil noma i-Zoloft angaba yingozi kakhulu futhi abulale. Ukusetshenziswa kwe-MAO inhibitors kufanele kwehlukaniswe nama-SSRI ngezinsuku eziyi-14. Ukusebenzisa i-Paxil noma i-Zoloft ngokuhlangana nezinye izidakamizwa ezandisa i-serotonin, kanye namanye ama-SSRIs, ama-SNRIs, noma ama-tricyclic antidepressants kungandisa ubungozi be-serotonin syndrome. Ama-Aspirin namanye ama-NSAID akufanele asetshenziswe ne-Paxil noma iZoloft ngoba angakhuphula ubungozi bokuphuma kwegazi. Ezinye izidakamizwa eziningi zingasebenzisana nePaxil noma iZoloft. Xhumana nomhlinzeki wakho wezokunakekelwa kwempilo ukuthola uhlu oluphelele.
| Izidakamizwa | Isigaba Sezidakamizwa | I-Paxil | Zoloft |
| I-Eldepryl (selegiline) I-Azilect (rasagiline) I-Nardil (phenelzine) I-Parnate (i-tranylcypromine) | MAOI | Yebo | Yebo |
| I-Tryptophan | I-amino acid | Yebo | Yebo |
| I-Orap (pimozide) | I-Antipsychotic | Yebo | Yebo |
| I-Triptans (imithi ye-migraine) ILithium Fentanyl I-Ultram (tramadol) ISt. John's Wort | Izidakamizwa ezandisa i-serotonin | Yebo | Yebo |
| I-Prozac (fluoxetine) I-Celexa (citalopram) I-Lexapro (escitalopram) I-Luvox (i-fluvoxamine) I-Viibryd (vilazodone) | Ama-SSRIs | Yebo | Yebo |
| ICymbalta (duloxetine) I-Effexor (venlafaxine) I-Pristiq (desvenlafaxine) | Ama-SNRIs (i-serotonin ne-norepinephrine reuptake inhibitors) | Yebo | Yebo |
| I-Mellaril (thioridazine) | I-Antipsychotic | Yebo | Yebo |
| I-Coumadin (warfarin) | I-Anticoagulant | Yebo | Yebo |
| U-Elavil (amitriptyline) I-Pamelor (nortriptyline) | I-Tricyclic antidepressants | Yebo | Yebo |
| I-Aspirin I-Aleve (naproxen) I-Motrin, Advil (ibuprofen) | I-NSAID (izidakamizwa ezingezona ukuvuvukala ezingezona i-steroidal) | Yebo | Yebo |
| Theophylline | I-Methylxanthine | Yebo | Akunjalo |
| I-Dilantin (phenytoin) I-Phenobarbital | Ama-anticonvulsants | Yebo | Yebo |
Izexwayiso zePaxil vs. Zoloft
Wonke ama-anti-depressants, afaka iPaxil kanye neZoloft, eza nesixwayiso esibhokisi, okuyisixwayiso esiqine kakhulu esidingwa yi-FDA. Ama-anti-depressants akhulisa ubungozi bemicabango yokuzibulala nokuziphatha ezinganeni, ebusheni nasebancane. Ukudangala kanye nokunye ukuphazamiseka kwengqondo nakho kwandisa ingozi yokuzibulala.
Iziguli zanoma imuphi ubudala ezithatha imishanguzo yokucindezela kufanele ziqashwe ngeso elibukhali uma kukhona izimpawu zokushintsha kokuziphatha, nokuzibulala, ikakhulukazi ezinyangeni ezimbalwa zokuqala zokwelashwa futhi uma kukhona ushintsho kumthamo olwenzekayo. Imindeni kanye nabanakekeli kufanele futhi baqaphe isiguli, futhi bazise lowo obamisile nganoma yiziphi izinkinga.
Ngokwengeziwe, kukhona ezinye izixwayiso eziza nePaxil kanye neZoloft:
- Ngaphambi kokuba ukwelashwa kuqale, isiguli kufanele sihlolwe isifo se-bipolar. Iziguli ezinesifo se-bipolar ekuqaleni zingase zibe nesiqephu sokucindezeleka. I-Paxil noma i-Zoloft ngeke isebenzele ukuphazamiseka kwe-bipolar, futhi empeleni ingase ibe yimbi kakhulu i-bipolar disorder.
- Ukuthuthuka kwesimo esibi, esingaba yingozi yokuphila esibizwa isifo se-serotonin kwenzeke ngama-SSRI antidepressants. Izimpawu zesifo se-serotonin zingabandakanya ukuxokozela, ukubona izinto ezingekho, ukushaya kwenhliziyo okusheshayo, isiyezi, ukujuluka, ukugeleza, ukushintshashintsha kwengcindezi yegazi, ukundindizela, ukungalawuleki, ukubamba, isicanucanu, ukuhlanza noma uhudo.
- Ubungozi be-serotonin syndrome buyanda lapho ezinye izidakamizwa zithathwa kanye ne-Paxil noma i-Zoloft nazo ezandisa i-serotonin, njengeama-triptans, ama-tricyclic antidepressants, i-fentanyl, i-lithium, i-tramadol, i-buspirone, i-tryptophan, i-amphetamines ne-St. John's Wort.
- Inhlanganisela yePaxil noma iZoloft eneMAOI (monoamine oxidase inhibitor) iyingozi futhi iyaphikiswa. Izibonelo ze-MAOI zifaka phakathi i-Eldepryl (selegiline), i-Azilect (rasagiline), iNardil (phenelzine), neParnate (tranylcypromine). Kufanele kube nokuhlukaniswa kwezinsuku eziyi-14 phakathi kokusebenzisa i-MAOI ne-SSRI.
- IPaxil noma iZoloft akufanele isetshenziswe neMellaril (thioridazine); inhlanganisela ingadala i-ventricular arrhythmia futhi iholele ekufeni okungazelelwe.
- Sebenzisa ngokuqapha ezigulini ezinokuquleka.
- Lapho i-Paxil noma i-Zoloft imisiwe, umuthi kufanele uthayishwe kancane kancane futhi ungamiswa ngokuzuma, ukugwema izimpawu zokuhoxa.
- I-Hyponatremia (i-sodium ephansi egazini) kungenzeka, ngenxa ye-SIADH (syndrome yeuketshezi olungavumelekile lwe-antidiuretic hormone). Iziguli ezithatha isisu noma lezo eziphelelwe amanzi emzimbeni zisengozini enkulu.
- Imithi ye-SSRI ingakhuphula ubungozi bokuphuma kwegazi futhi akumele isetshenziswe ngokuhlangene ne-aspirin noma amanye ama-NSAID afana ne-ibuprofen noma i-naproxen, noma abanciphisi begazi abanjengoCoumadin (warfarin).
- Ukuqapha ingozi yokuphuka kwethambo.
- I-Paxil noma i-Zoloft ingadala ukuvuleka kwamaphuphu futhi ingadala ukuhlaselwa kokuvalwa kwama-engeli ezigulini ezinama-engeli amancane we-anatomically.
Ukuvezwa kwe-Paxil ku-trimester yokuqala yokukhulelwa kungaholela ekukhubazekeni kwenhliziyo embungwini futhi kufanele kugwenywe ngokuvamile. Imvamisa, udokotela wakho angathola enye indlela ephephile yokwelapha ongayisebenzisa ngenkathi ukhulelwe. Uma uku-Paxil futhi uthola ukuthi ukhulelwe, xhumana ne-OB-GYN yakho ngokushesha ukuze uthole isiqondiso.
Imibuzo ebuzwa njalo mayelana nePaxil neZoloft
Kuyini iPaxil?
I-Paxil (eyaziwa nangokuthi igama layo elijwayelekile elithi paroxetine) ngumuthi ovunyelwe yi-FDA esigabeni semithi se-SSRI, esisetshenziselwa ukwelapha ukuphazamiseka okukhulu kwengcindezi, i-OCD, nezinkinga zokukhathazeka.
Kuyini iZoloft?
I-Zoloft (i-sertraline) ngumuthi ovunyelwe yi-FDA esigabeni semithi se-SSRI, esisetshenziselwa ukwelapha ukuphazamiseka okukhulu kokucindezeleka. Ibuye isetshenziswe ngaphandle kwelebuli ukwelapha ukuphazamiseka kokukhathazeka.
Ngabe iPaxil neZoloft ziyefana?
I-Paxil ne-Zoloft ziyefana, kodwa azifani. Ngenkathi zombili zingama-SSRI futhi zisebenza ngendlela efanayo, zinokungafani kwezinkomba, i-dosing, nemiphumela emibi, njengoba kuchaziwe ngenhla. Ezinye izidakamizwa ze-SSRI zifaka phakathi I-Prozac ( i-fluoxetine ), UCelexa (citalopram), I-Lexapro (escitalopram), Viibryd (vilazodone), kanye noLuvox (fluvoxamine).
Ngabe iPaxil noma iZoloft ingcono? / Ngabe i-sertraline ingcono kune-paroxetine?
Zombili lezi zidakamizwa zibekezeleleke kahle futhi zingasebenza kakhulu ekwelapheni ukucindezeleka kanye nokuphazamiseka kokukhathazeka. Yize iZoloft ikhonjiswa kuphela ngokudangala, odokotela abaningi bayayinikeza ukuthi nayo ibe nokukhathazeka. Buza udokotela wakho ukuthi ngabe enye yalezi zidakamizwa ingakulungela yini.
Ngingayisebenzisa yini iPaxil noma iZoloft ngenkathi ngikhulelwe?
I-Paxil ingaba yingozi uma isetshenziswa ku-trimester yokuqala yokukhulelwa, kanti i-Zoloft ingaba yingozi uma isetshenziswa ku-trimester yesithathu. Kodwa-ke, impilo yengqondo ibalulekile — ukucindezelwa nokukhathazeka okungalashwa nakho kungaba yingozi.
Xhumana nodokotela wakho mayelana nokusebenzisa umuthi ohlukile uma ukhulelwe. Uma usuvele uthatha iPaxil noma iZoloft futhi uthola ukuthi ukhulelwe, xhumana nomhlinzeki wakho wezokunakekelwa kwezempilo ukuthola iseluleko sezokwelapha.
Ngingasebenzisa iPaxil noma iZoloft ngotshwala?
Imininingwane yomkhiqizi yazo zombili izidakamizwa ikhombisa ukuthi iziguli akufanele ziphuze utshwala ngenkathi zithatha iPaxil noma iZoloft.
Ingabe iZoloft ne-sertraline into efanayo?
Yebo. I-Zoloft yigama lomuthi. I-Sertraline igama elejwayelekile. Iningi leziguli zithatha i-sertraline, ejwayelekile.
Yimaphi ama-anti-depressants anemiphumela emibi kakhulu?
Zonke izidakamizwa zokulwa nengcindezi ziza nohlu lwezexwayiso futhi okuqhamuka uma udla imishanguzo , njengoba kuvezwe ngenhla. Kodwa-ke, ngoba wonke umuntu wehlukile, abantu abaningi basabela ngendlela ehlukile kuma-anti-depressants ahlukene. Kwesinye isikhathi kudinga isilingo nephutha ukuthola okukusebenzela okungcono kakhulu, okunemiphumela engemihle.
Ingabe iPaxil iyisidambisi esihle sokucindezela ukucindezeleka?
Onke ama-anti-depressants e-SSRI adlule ezivivinyweni eziningi zemitholampilo ukusungula ukuphepha nokusebenza ngempumelelo. Xhumana nomhlinzeki wakho wezokunakekelwa kwempilo ukuze ubone ukuthi ngabe iPaxil iyisidakamizwa esifanele yini kuwe.
