I-Enbrel vs Humira: Umehluko Omkhulu nokufana

Izidakamizwa Vs. Umngani

I-Enbrel (etanercept) neHumira (adalimumab) yimithi ekhonjisiwe yokwelapha i-rheumatoid arthritis (RA). Yomibili le mithi ihlukaniswe njengezivimbeli ze-tumor necrosis factor (TNF). Basebenza ngokuvimba i-TNF, into yemvelo ebandakanyeka ezinkambisweni zokuvuvukala emzimbeni. Ngokuvimba le nto, u-Enbrel noHumira basebenzela ukunciphisa ukuvuvukala nezimpendulo zomzimba ezibhekele izimpawu ze-RA.

Umhlanganisi

I-Enbrel igama lomkhiqizo le-etanercept. Isetshenziselwa ukwelapha i-rheumatoid ne-psoriatic arthritis. Ingaphatha nezinye izimo zokuvuvukala ezifana ne-polyarticular juvenile idiopathic arthritis (JIA) ne-ankylosing spondylitis.

I-Enbrel iyatholakala njengomjovo ongalawulwa ngaphansi kwesikhumba kanye noma kabili ngesonto. Ngokuya ngesifo eselaphwayo, i-Enbrel inganikezwa njenge-syringe ekhethiwe ye-25 mg / 0.5 ml. Inganikezwa futhi njenge-SureClick Autoinjector engahle ibe lula futhi isebenziseke kalula kwabanye abantu.

Humira

I-Humira yaziwa ngegama layo lamakhemikhali, i-adalimumab. I-Humira ingaphatha i-rheumatoid arthritis, i-psoriatic arthritis, i-juvenile idiopathic arthritis, ne-ankylosing spondylitis. Ngokungafani ne-Enbrel, iHumira nayo ingasetshenziselwa isifo sikaCrohn nesifo sezilonda emathunjini, phakathi kwezinye izimo zokuvuvukala.

I-Humira iza njenge-40 mg / 0.4 mL, 40 mg / 0.8 mL, kanye ne-80 mg / 0.8 mL ipeni elisebenzisayo elilodwa. Amasirinji agcwaliswe ngaphambili ngamandla ahlukahlukene ayatholakala ukuze asetshenziswe. I-Humira dosing incike esimweni eselaphekwayo yize kuvame ukunikezwa njalo ngesonto nge-arthritis.

Enbrel vs Humira Side by Side Ukuqhathanisa

U-Enbrel noHumira babelana ngezici eziningana ezibenza babe nezindlela zokwelashwa ezingaba khona. Noma kunokufana okuningi, kukhona umehluko phakathi kwalokhu okubili. Zombili lezi zidakamizwa zingaqhathaniswa ngokuqhubekayo ngezansi.

Umhlanganisi	Humira
Okumiselwe i
Isifo samathambo I-juvenile idiopathic arthritis I-psoriatic arthritis I-plaque psoriasis I-Ankylosing spondylitis	Isifo samathambo I-juvenile idiopathic arthritis I-psoriatic arthritis I-plaque psoriasis I-Ankylosing spondylitis Isifo sikaCrohn I-ulcerative colitis I-Hidradenitis suppurativa
Ukuhlukaniswa Kwezidakamizwa
Isigaxa se-tumor necrosis factor (TNF)	Isigaxa se-tumor necrosis factor (TNF)
Umkhiqizi
Amgen	AbbVie
Imiphumela emibi ejwayelekile
Izifo Ukutheleleka okuphezulu okuphefumulayo Ukuphendula kwesayithi lokujova	Izifo Ukuphendula kwesayithi lokujova Ubuhlungu bekhanda I-Rash
Ingabe kukhona okujwayelekile?
Akukho okujwayelekile okutholakalayo ukuthengwa	Akukho okujwayelekile okutholakalayo ukuthengwa
Ngabe ihlanganiswe umshwalense?
Iyahluka kuya ngomhlinzeki wakho	Iyahluka kuya ngomhlinzeki wakho
Amafomu Esikali
Umjovo ongaphansi	Umjovo ongaphansi
Inani lentengo emaphakathi
$ 6,100 nge-4, 50 mg / ml yesisombululo somjovo	$ 5,773 ngamakhithi amabili angaphansi kwesikhumba
Intengo Yesaphulelo Esingabodwa
Inani le-Enbrel	Intengo yeHumira
Ukusebenzisana Kwezidakamizwa
Imishanguzo ebukhoma Anakinra Abatacept ICyclophosphamide	Imishanguzo ebukhoma Anakinra Abatacept
Ngingakwazi ukusebenzisa ngenkathi ngihlela ukukhulelwa, ngikhulelwe, noma ngincelisa ibele?
I-Enbrel isesigabeni sokukhulelwa B. Akukho monakalo wesisu osungulwe ezifundweni zezilwane. Kodwa-ke, ukulimala kombungu akunqatshelwe. Xhumana nodokotela mayelana nezinyathelo okufanele uzithathe uma uhlela ukukhulelwa noma ukuncelisa ibele.	I-Humira isesigabeni sokukhulelwa B. Akukho monakalo wombungu osungulwe ezifundweni zezilwane. Kodwa-ke, ukulimala kombungu akunqatshelwe. Xhumana nodokotela mayelana nezinyathelo okufanele uzithathe uma uhlela ukukhulelwa noma ukuncelisa ibele.

Isifinyezo

I-Enbrel (etanercept) ne-Humira (adalimumab) imijovo efanayo kadokotela elapha isifo samathambo. Ngenkathi besebenza ngezindlela ezifanayo njengabavimbeli be-TNF, bayahluka ngendlela abakhiwe futhi basetshenziswe ngayo. Yize yomibili le mithi ilapha isifo samathambo, uHumira angaphinde alaphe nezinye izifo zokuvuvukala ezifana nesifo sikaCrohn nesifo sezilonda.

Kubalulekile ukuthi wazi ukuthi i-TNF blockers ayithathwa njengeyokwelashwa komugqa wokuqala wesifo samathambo. Esikhundleni salokho, kubhekwa lapho ezinye izindlela zokwelashwa zingasebenzi.

Zombili lezi zidakamizwa zenziwa njalo ngesonto ngokusebenza okufanayo. I-Enbrel inganikezwa njengesirinji egcwaliswe ngaphambili noma i-SureClick Autoinjector ngenkathi i-Humira itholakala njengesirinji noma ipeni eligcwaliswe ngaphambili.

Yomibili le mithi akufanele inikezwe kanye nemithi yokugoma ebukhoma. Lokhu kungenxa yengozi eyengeziwe yokutheleleka uma usebenzisa i-Enbrel noma iHumira. Izixwayiso zebhokisi elimnyama zengozi eyandayo yesifo sofuba nazo zikhona ku-Enbrel noHumira. Ngaphandle kwalokho, imiphumela emibi ejwayelekile ivame ukukhawulelwa ekuphenduleni kwesiza somjovo njengokubomvu okuncane nokucasuka.

Ngenxa yokufana kwazo ekusebenzeni nasekusebenzeni kahle, kungahle kukhethwe i-Enbrel noma iHumira ngokuya ngesimo sakho sonke. Kubalulekile ukuxoxa ngokwelashwa ngemithi nodokotela ukuze unqume inketho engcono kakhulu. Uma uphethwe yisifo samathambo, ezinye izindlela zokwelapha ziyatholakala.