I-Famotidine vs. omeprazole: Umehluko, ukufana, nokuthi yikuphi okungcono kuwe

Izidakamizwa Vs. Umngani

Ukubuka konke kwezidakamizwa nokwehluka okuyinhloko | Izimo zilashwa | Ukusebenza | Ukutholakala komshuwalense nokuqhathaniswa kwezindleko | Okuqhamuka uma udla imishanguzo | Ukusebenzisana kwezidakamizwa | Izexwayiso | Imibuzo evame ukubuzwa

I-Famotidine ne-omeprazole yizidakamizwa ezimbili ezijwayelekile ezingasetshenziswa ukwelapha izinkinga eziningana zokugaya ukudla. Noma ngabe ubhekene nesilonda se-duodenal noma izimpawu zesifo se-reflux se-gastroesophageal (GERD), umhlinzeki wakho wezokunakekelwa kwezempilo angancoma umuthi onjenge-famotidine noma i-omeprazole. Le mithi isebenza ngezindlela ezifanayo zokwehlisa ukukhiqizwa kwe-asidi esiswini. Yize zivame ukutholakala ngaphezu kwe-counter (OTC), i-famotidine ne-omeprazole nazo zingabekwa ngudokotela.

Ama-Antacids afana namaTum (calcium carbonate) avame ukuvivinywa kuqala ngaphambi kokuqala kokuthile okuqine njenge-H2 blocker, njenge-famotidine, noma i-proton pump inhibitor (PPI), efana ne-omeprazole. Ngenhlanhla, i-famotidine ne-omeprazole yimithi ejwayelekile etholakala kabanzi. Ngenkathi zombili zibhekwa njengezinciphisi ze-asidi, ziyehluka ekusebenzeni kwazo nokuthi zisetshenziswa kanjani.

Uyini umehluko omkhulu phakathi kwe-famotidine ne-omeprazole?

I-Famotidine

I-Famotidine (famotidine amakhuphoni) yaziwa nangokuthi igama layo lomkhiqizo, i-Pepcid. Ihlukaniswe njenge- I-H2 blocker noma umphikisi we-H2-receptor. I-Famotidine isebenza ngokuvimba into ebizwa nge-histamine esiswini ukwehlisa ukukhiqizwa kwe-asidi.

Imiphumela ye-famotidine (imininingwane eyengeziwe ye-famotidine) ingazwakala kungakapheli ihora elilodwa futhi ingahlala emahoreni ayi-12 ngokuya ngomthamo othathiwe. Amaphilisi e-Famotidine avame ukuthathwa kanye noma kabili ngosuku ngezinkinga zokugaya ukudla.

Omeprazole

I-Omeprazole (omeprazole amakhuphoni) ingathengwa njengesidakamizwa esinegama elibizwa nge-Prilosec noma i-Prilosec OTC. Ngokungafani ne-famotidine, i-omeprazole ihlukaniswa njenge- iproton pump inhibitor (PPI) . Isebenza ngokuvimba ngqo amaphampu we-proton kolwelwesi lwesisu ukumisa ukukhiqizwa kwe-asidi.

Imiphumela ye-omeprazole (imininingwane eminingi ye-omeprazole) ingazwakala ngokushesha kungakapheli ihora elilodwa ngemuva kokuyithatha. Noma kunjalo, umphumela wayo we-antisecretory ungahlala kuze kufike ku- Amahora angama-72 , ende kakhulu kunaleyo ye-famotidine. I-Omeprazole ivame ukuthathwa kanye ngosuku.

Umehluko omkhulu phakathi kwe-famotidine ne-omeprazole
	I-Famotidine	Omeprazole
Isigaba sezidakamizwa	H2 Isivimbeli	IProton Pump Inhibitor (PPI)
Isimo somkhiqizo / ejwayelekile	Uhlobo lomkhiqizo nohlobo olujwayelekile luyatholakala	Uhlobo lomkhiqizo nohlobo olujwayelekile luyatholakala
Ngubani igama lomkhiqizo?	I-Pepcid	Prilosec
Izidakamizwa zingena ngaziphi izinhlobo?	Ithebhulethi Ukumiswa kuketshezi	I-Capsule Ithebhulethi Ukumiswa kuketshezi
Uyini umthamo ojwayelekile?	Izilonda ze-duodenal: 40 mg kanye ngosuku noma ama-20 mg kabili ngosuku I-GERD: 20 mg kabili ngosuku	Izilonda ze-duodenal: 20 mg kanye ngosuku I-GERD: 20 mg kanye ngosuku
Yelashwa isikhathi esingakanani?	Kuze kube amasonto ayisithupha noma ayisishiyagalombili noma ngaphezulu ngokuya ngesimo esiphathwayo	Kuze kube amasonto ama-4 noma ama-8 noma ngaphezulu ngokuya ngesimo esiphathwayo
Ubani ovame ukusebenzisa umuthi?	Abantu abadala nezingane abaneminyaka engu-17 nangaphezulu. Izingane ezineminyaka engu-1 kuya kwengu-16 ubudala zingasebenzisa lesi sidakamizwa ngemiyalo evela kudokotela.	Abantu abadala nezingane abaneminyaka engu-17 nangaphezulu. Izingane ezineminyaka engu-1 kuya kwengu-16 ubudala zingasebenzisa lesi sidakamizwa ngemiyalo evela kudokotela.

Izimo eziphathwa yi-famotidine ne-omeprazole

I-Famotidine ne-omeprazole kungabekwa ukwelapha i-GERD, izilonda ze-duodenal, nezilonda zesisu. Yomibili le mithi nayo ivunyelwe ukwelashwa yi-FDA ukuqina kwesisu (EE), noma ukuvuvukala kolwelwesi ku-esophagus. I-esophagitis ekhukhulayo ivame ukubangelwa yi-GERD.

I-prescription famotidine ne-omeprazole nayo ingasetshenziselwa ukwelapha izimo ze-hypersecretory, njenge-Zollinger-Ellison syndrome. Le mithi ingasiza ekwehliseni i-asidi esiswini ebangelwa ukuphazamiseka okungavamile.

Ufuna intengo engcono kakhulu ku-Famotidine?

Bhalisela izexwayiso zentengo ze-Famotidine bese uthola ukuthi intengo ishintsha nini!

Thola Izaziso Zentengo

Izinhlobo ze-over-the-counter (OTC) ze-famotidine ne-omeprazole zingasetshenziselwa ukukhululeka kwesinye isikhathi noma kaningi isilungulela . I-Acid reflux, eyenzeka lapho i-asidi yesisu ibuyiselwa emuva emphinjeni, kuyimbangela ejwayelekile yokushiswa yinhliziyo.

I-Omeprazole ivunyelwe ukwelashwa nge-FDA I-Helicobacter pylori , noma H. pylori , izifo. Amagciwane abangela lokhu kutheleleka ahlasela ulwelwesi lwesisu, olungabangela izilonda ezisemabeleni. Ukwelashwa kufaka i-omeprazole ehlangene ne-antibiotic efana ne-amoxicillin noma i-clarithromycin.

Isimo	I-Famotidine	Omeprazole
Isifo se-reflux se-gastroesophageal (GERD)	Yebo	Yebo
Izilonda ze-duodenal	Yebo	Yebo
Izilonda zesisu	Yebo	Yebo
Isilungulela	Yebo	Yebo
Ukuqothuka kwesisu	Yebo	Yebo
Izimo ze-hypersecretory	Yebo	Yebo
H. pylori ukutheleleka	Akunjalo	Yebo
I-urticaria engapheli (ukulunywa)	Ngaphandle kwelebula	Akunjalo
I-Barrett esophagus	Akunjalo	Ngaphandle kwelebula

Ingabe i-famotidine noma i-omeprazole isebenza kahle kakhulu?

Kokubili i-famotidine ne-omeprazole kungaba yimithi esebenzayo yokwelapha i-GERD nezinye izimo zokugaya ukudla. Kodwa-ke, ukuvumelana okujwayelekile ukuthi i-omeprazole iyisidakamizwa esinamandla kakhulu kune-famotidine.

Ukuhlolwa okungahleliwe, ukuhlolwa komtholampilo kubonise ukuthi ama-PPIs kusebenza kakhulu ekwelapheni izilonda zesisu kunama-H2 blocker. Ama-PPIs atholakele akhulisa kakhulu ukuphulukiswa kwezilonda uma kuqhathaniswa nama-H2 blocker. Akukho mehluko obalulekile otholakele phakathi kwama-PPIs afundwe, afaka i-Prevacid (lansoprazole), Protonix (pantoprazole), ne-Aciphex (rabeprazole).

Kubantu abathatha izinciphisi zegazi, njenge-clopidogrel ne-aspirin, i-PPI noma i-H2 blocker ingasetshenziswa ukuvimbela izilonda. Ukubuyekezwa okuhlelekile okukodwa kutholile ukuthi ama-PPIs ayengaphezulu kwama-H2 blocker ku- ukuvimbela izilonda zesisu . Izifundo ekubuyekezweni ikakhulu ziqhathanisa i-Prilosec (omeprazole) noma i-Nexium (esomeprazole) ne-Pepcid (famotidine) noma i-Zantac (ranitidine).

Kubalulekile ukuthi ufune iseluleko sezempilo kumhlinzeki wakho wezokunakekelwa kwempilo ngaphambi kokuthatha i-famotidine noma i-omeprazole. Isidakamizwa esisebenza kangcono ekugcineni yiso esisebenza kangcono esimeni sakho.

OKUSHIWO: Amakhuphoni eLansoprazole | Amakhuphoni we-Protonix | Amakhuphoni kaRabeprazole | Amakhuphoni e-Clopidogrel | Ama-Aspirin amakhuphoni | Amakhuphoni e-Prilosec | Amakhuphoni we-Nexium | Amakhuphoni e-Pepcid | Amakhuphoni eZantac

Ufuna intengo enhle nge-Omeprazole?

Bhalisela izexwayiso zentengo ye-Omeprazole bese uthola ukuthi intengo ishintsha nini!

Thola Izaziso Zentengo

Ukuhlanganiswa nokuqhathaniswa kwezindleko kwe-famotidine kuqhathaniswa ne-omeprazole

Iningi lezinhlelo ze-Medicare Part D kanye nezinye izinhlelo zomshuwalense zizohlanganisa amaphilisi ejwayelekile e-famotidine. I-Famotidine ingabiza intengo yokuthengisa engu- $ 100 ngokwesilinganiso uma ungenayo imishwalense. Uma ufuna isivumelwano esingcono kakhulu, iSingleCare inikeza amakhuphoni esaphulelo kuzidakamizwa ezifana ne-famotidine. Ngekhuphoni le-SingleCare famotidine, ungalindela ukukhokha u- $ 9- $ 30.

Zama ikhadi lesigqebhezana le-SingleCare

Ama-capsules we-Omeprazole abambezelekile akhululwa ambozwe yizinhlelo eziningi zeMedicare nezomshuwalense. Izindleko zokuthengisa ezijwayelekile ze-omeprazole cishe zingama- $ 70 ngokwesilinganiso. Kumaphilisi we-omeprazole ejwayelekile, ungasebenzisa ikhadi lesigqebhezana le-SingleCare ukwehlisa le ndleko. Ngekhuphoni le-SingleCare omeprazole, unganciphisa intengo ifike ku- $ 15 ngamaphilisi angama-30 20 mg.

	I-Famotidine	Omeprazole
Ngokuvamile embozwe umshwalense?	Yebo	Yebo
Imbozwe ngokujwayelekile yi-Medicare?	Yebo	Yebo
Umthamo ojwayelekile	Amaphilisi angama-20 mg (inani lama-60)	Ama-capsules angama-20 mg (ubuningi bama-30)
I-Medicare copay ejwayelekile	$ 0– $ 21	$ 0– $ 19
Izindleko ze-SingleCare	$ 9- $ 30	$ 15 +

Imiphumela emibi ejwayelekile ye-famotidine ne-omeprazole

Imiphumela emibi kakhulu ye-famotidine ne-omeprazole yikhanda, isiyezi, ukuqunjelwa, nohudo. Eminye imiphumela emibi yamathumbu ivamile futhi ifaka phakathi isisu, isicanucanu nokuhlanza. I-Omeprazole nayo ingadala ukuqunjelwa noma igesi.

Imiphumela emibi kakhulu ifaka ukusabela okweqile kunoma yiziphi izithako ezikule mithi. Ukusabela okweqile kungabandakanya ukuqhuma noma inkinga yokuphefumula. Funa usizo lwezokwelapha uma uhlangabezana nemiphumela emibi kakhulu.

	I-Famotidine	Omeprazole
Imiphumela emibi	Kusebenza?	Imvamisa	Kusebenza?	Imvamisa
Ubuhlungu bekhanda	Yebo	≥1%	Yebo	7%
Isiyezi	Yebo	≥1%	Yebo	amaphesenti amabili
Ukuqunjelwa	Yebo	≥1%	Yebo	amaphesenti amabili
Uhudo	Yebo	≥1%	Yebo	4%
Isisu esibuhlungu	Yebo	<1%	Yebo	5%
Isicanucanu	Yebo	<1%	Yebo	4%
Ukuhlanza	Yebo	<1%	Yebo	3%
Ukuqhuma kwesisu	Akunjalo	-	Yebo	3%

Lokhu kungenzeka kungabi uhlu oluphelele. Xhumana nodokotela wakho noma usokhemisi ngemiphumela engemihle engaba khona.
Umthombo: DailyMed ( sibhabha ), IDailyMed ( omeprazole )

Ukusebenzisana kwezidakamizwa kwe-famotidine kuqhathaniswa ne-omeprazole

I-Famotidine ngokuyinhloko ihlangana nezidakamizwa ezincike ku-asidi esiswini ukumuncwa. Le mithi ifaka izidambisigciwane, njenge-atazanavir ne-rilpivirine, nama-antifungal, njenge-ketoconazole ne-itraconazole. Ukuthatha i-famotidine kunganciphisa ukumuncwa kwalezi zidakamizwa futhi kwehlise ukusebenza kwazo konke.

OKUSHIWO: Amakhuphoni e-Atazanavir | Yini i-Atazanavir? | Amakhuphoni weKetoconazole | Kuyini iKetoconazole? | Amakhuphoni e-Itraconazole | Yini i-Itraconazole?

I-Famotidine nayo ingaxhumana ne-tizanidine, a isiduduzi semisipha leyo icutshungulwa yi-CYP1A2 enzyme esibindini. I-Famotidine ingakhuphula amazinga we-tizanidine emzimbeni angaholela ekucindezelweni kwegazi okuphansi (i-hypotension), ukushaya kwenhliziyo okuhamba kancane (i-bradycardia), noma ukozela ngokweqile.

I-Omeprazole ibuye isebenzisane neminye imishanguzo yokuthithibalisa igciwane lengculazi, engaholela ekwehleni kokusebenza kwayo. Ngokungafani ne-famotidine, i-omeprazole ingasebenzisana nezidakamizwa ezicutshungulwa ama-enzyme e-CYP2C19 ne-CYP3A4 esibindi. Le mithi ingafaka i-tacrolimus ne-rifampin, phakathi kwezinye izidakamizwa.

I-Omeprazole ingasebenzisana ne-warfarin futhi inyuse ingozi yokuphuma kwegazi ngokungajwayelekile. Ukuthatha i-omeprazole nge-immunosuppressant ebizwa nge-methotrexate kungaholela kubuthi be-methotrexate.

Izidakamizwa	Isigaba Sezidakamizwa	I-Famotidine	Omeprazole
Atazanavir I-Rilpivirine UNelfinavir ledipasvir / sofosbuvir I-Fosamprenavir	Izidambisigciwane	Yebo	Yebo
U-Erlotinib I-Dasatinib	Ukwelashwa ngamakhemikhali	Yebo	Yebo
Ketoconazole I-Itraconazole	I-Antifungal	Yebo	Yebo
I-Tizanidine	Isithambisi semisipha	Yebo	Akunjalo
Tacrolimus IMethotrexate	I-Immunosuppressant	Akunjalo	Yebo
I-Warfarin	I-Anticoagulant	Akunjalo	Yebo
I-Rifampin	Imithi elwa namagciwane	Akunjalo	Yebo

Lokhu kungenzeka kungabi uhlu oluphelele lwako konke ukuhlangana kwezidakamizwa okungenzeka. Xhumana nodokotela ngayo yonke imithi okungenzeka uyayiphuza.

Izexwayiso ze-famotidine ne-omeprazole

Izimpawu ezinzima ze-GERD noma izilonda kungaba uphawu lomdlavuza wamathumbu kwabanye abantu. Ukuhlolwa okungeziwe nokuqapha kungadingeka kubantu abangaphenduli ekwelashweni nge-PPI noma i-H2 blocker.

I-Famotidine kufanele isetshenziswe ngokuqapha ku abantu asebekhulile noma labo abanezinkinga zezinso. Ukusetshenziswa kwe-Famotidine kungaholela engcupheni eyandayo ye-CNS (uhlelo oluphakathi lwezinzwa) imiphumela emibi efana nokudideka, i-delirium, ne-hallucinations.

I-Omeprazole ivamise ukuba nezixwayiso eziningi kanye nezinyathelo zokuqapha ezihambisana nayo uma iqhathaniswa ne-famotidine. Ngokungafani ne-famotidine, i-omeprazole namanye ama-PPI angakhuphula ubungozi bokukhumuzeka kwamathambo namathambo lapho kusetshenziswa isikhathi eside.

Ukusetshenziswa kwe-Omeprazole, ikakhulukazi esimweni sesibhedlela, kungaholela engcupheni yokwanda IClostridium difficile uhudo oluhlobene. Ucwaningo oluthile lwathola ukuthi ama-proton pump inhibitors ahlotshaniswa ne- izingozi eziningi zemiphumela emibi kakhulu njengenyumoniya futhi C. okuhlukile izifo . Ucwaningo luthathe idatha ezibhedlela ezingama-71 futhi lwahlola ukusetshenziswa kwe-PPI ne-H2-blocker endaweni ethile yeziguli.

Imibuzo ebuzwa njalo nge-famotidine vs. omeprazole

Yini i-famotidine?

I-Famotidine ngumuthi we-H2 blocker osetshenziselwa ukwelapha i-GERD, izilonda ze-duodenal, nezilonda zesisu. Futhi kuvunyelwe i-FDA ukwelapha izimo ze-hypersecretory njenge-Zollinger-Ellison syndrome kubantu abadala. I-Famotidine iyindlela ejwayelekile yePepcid futhi ivame ukuthathwa kabili ngosuku.

Yini i-omeprazole?

I-Omeprazole iyi-proton pump inhibitor (PPI) evunyelwe yi-FDA ukwelapha izimo zokugaya ukudla ezifana ne-GERD nezilonda. Ibuye isetshenziselwe ukwelapha H. pylori izifo . I-Omeprazole yaziwa ngegama layo lomkhiqizo, Prilosec noma Prilosec OTC. Kuvame ukuthathwa kanye ngosuku amasonto amane kuya kwayisishiyagalombili.

Ngabe i-famotidine ne-omeprazole ziyefana?

I-Famotidine ne-omeprazole azifani. Yize belapha izinkinga ezifanayo zamathumbu, ziyizidakamizwa ezihlukile. I-Famotidine iyi-H2 blocker kanti i-omeprazole iyi-PPI.

Ngabe i-famotidine noma i-omeprazole ingcono?

I-Omeprazole ithathwa njengesidakamizwa esisebenza kangcono uma iqhathaniswa ne-famotidine. I-Omeprazole ihlala isikhathi eside emzimbeni nge imiphumela eyanda ngemuva kokuyithatha nsuku zonke . Lo mphumela wokuqoqeka awubonakali nge-famotidine. Kodwa-ke, i-omeprazole ingaba nemiphumela emibi kakhulu ehambisana nokusetshenziswa kwayo.

Ngingayisebenzisa i-famotidine noma i-omeprazole ngenkathi ngikhulelwe?

I-Famotidine ingaba nengozi encane yokulimaza ngesikhathi sokukhulelwa uma kuqhathaniswa ne-omeprazole. Xhumana nomhlinzeki wakho wezokunakekelwa kwempilo lapho ukhetha indlela ye- inketho yokwelashwa ngenkathi ukhulelwe noma ukuncelisa ibele.

Ngingayisebenzisa i-famotidine noma i-omeprazole ngotshwala?

I-Famotidine kufanele igwenywe ngotshwala. Ukuphuza utshwala ngenkathi uthatha i-famotidine kungakhuphula ubungozi bemiphumela ye-CNS njengokudideka noma ukozela. I-Omeprazole ingahle iphuze ngokuphuza utshwala ngokulinganisela. Kodwa-ke, ukuxuba imishanguzo notshwala kufanele kugwenywe lapho kunokwenzeka, ikakhulukazi uma ubona ukwanda kwemiphumela emibi.

Uyini umuthi ophephe kakhulu we-acid reflux?

Wonke umuntu uphendula imithi ngokuhlukile. Ngakho-ke, umuthi ophephe kakhulu we-acid reflux yiwo okusebenzela kangcono kakhulu ngemiphumela engemihle. Uma kuqhathaniswa ne-famotidine, i-omeprazole ingaba nengozi eyengeziwe ye- imiphumela emibi , njenge-osteoporosis, ikakhulukazi lapho isetshenziswa isikhathi eside.

Ingabe kulungile ukuthatha iPepcid nsuku zonke?

I-Pepcid ijwayele ukuthathwa nsuku zonke kuze kube amasonto ayisithupha, ayisishiyagalombili, noma ama-12 ngasikhathi. Isikhathi sokwelashwa sincike esimweni eselashwa. Khuluma nodokotela wakho ukuthola ukuthi kufanele uthathe i-Pepcid isikhathi esingakanani. Cabanga ngezinguquko zendlela yokuphila ngaphezu kwemithi yokusiza ukuqeda isilungulela esivame kakhulu.

Yimuphi umuthi osebenza ngokushesha wesilungulela?

Ama-Antacids ngokuvamile asebenza ngokushesha kakhulu ekwelapheni izimpawu zesilungulela. Ama-Antacids afana ne-Rolaids (i-calcium carbonate ne-magnesium hydroxide) (ama-Rolaids amakhuphoni) anganciphisa i-asidi kungakapheli imizuzu engama-30 ewathathiwe. Uma kuqhathaniswa ne-famotidine, i-calcium carbonate itholakale ine- ukuqala ngokushesha kwesenzo . Ngenkathi zinikeza ukukhululeka okusheshayo kwesilungulela, imiphumela ye-antacid ayihlali usuku lonke. Ama-H2 blockers nama-PPIs ahlala isikhathi eside futhi agcinelwe izimo ezingapheli zokugaya ukudla njenge-GERD.