IMeloxicam vs. Celebrex: Umehluko, ukufana, nokuthi yikuphi okungcono kuwe
Izidakamizwa Vs. UmnganiUkubuka konke kwezidakamizwa nokwehluka okuyinhloko | Izimo zilashwa | Ukusebenza | Ukutholakala komshuwalense nokuqhathaniswa kwezindleko | Okuqhamuka uma udla imishanguzo | Ukusebenzisana kwezidakamizwa | Izexwayiso | Imibuzo evame ukubuzwa
IMeloxicam neCelebrex yizidakamizwa ezingezona ukuvuvukala (ama-NSAID) ezisetshenziselwa ukwelapha i-arthritis. IMeloxicam inguqulo ejwayelekile yeMobic ngenkathi iCelebrex iyigama lomkhiqizo le-celecoxib. Zombili lezi zidakamizwa zisebenza ngokuvimbela ukukhishwa kwezinto ezivuthayo ezibizwa nge-prostaglandin. Ngokuvimba ukukhishwa kwabo emzimbeni, i-meloxicam neCelebrex kungadambisa izinhlungu, ukuvuvukala nokuvuvukala kwamalunga.
Ngenkathi womabili ama-NSAID elapha izinhlungu, anokuhluka okuthile ngendlela asetshenziswa ngayo neminye imiphumela emibi okufanele ayiqaphele. Ezinye izibonelo zama-NSAID zifaka ibuprofen, naproxen, ne-diclofenac.
Uyini umehluko omkhulu phakathi kwe-Meloxicam vs. Celebrex?
I-Meloxicam (amakhuphoni e-Meloxicam | Imininingwane ye-Meloxicam) umuthi ojwayelekile ovame ukuthathwa kanye ngosuku nge-osteoarthritis, i-rheumatoid arthritis, ne-juvenile rheumatoid arthritis. I-Meloxicam ingafinyelela emazingeni aphezulu egazini kuze kufike emahoreni ayisithupha ngemuva kokuthatha umthamo. Kumuncwa isikhathi eside uma kuqhathaniswa neCelebrex nokunye Ama-NSAID .
UCelebrex (celecoxib) ngumuthi wegama lomkhiqizo ongathathwa kanye noma kabili nsuku zonke kuye ngohlobo lwe-arthritis elashwa. ICelebrex (amakhuphoni kaCelebrex | imininingwane yeCelebrex) nayo ingaphatha amajaqamba okuya esikhathini. Ukuphakama okuphezulu kwe-celecoxib kufinyelelwa emahoreni ama-3 ngemuva kokuphathwa. Ngakho-ke, imiphumela yayo ikhiqizwa ngokushesha okukhulu kepha ihlala isikhathi esifushane ngokuqhathaniswa ne-meloxicam.
| Umehluko omkhulu phakathi kwe-Meloxicam vs. Celebrex | ||
|---|---|---|
| UMeloxicam | UCelebrex | |
| Isigaba sezidakamizwa | Izidakamizwa ezingezona ukuvuvukala (i-NSAID) | Izidakamizwa ezingezona ukuvuvukala (i-NSAID) |
| Isimo somkhiqizo / ejwayelekile | Uhlobo olujwayelekile luyatholakala | Uhlobo olujwayelekile luyatholakala |
| Ngubani igama elijwayelekile? Ngubani igama lomkhiqizo? | Igama elijwayelekile: Meloxicam Igama lomkhiqizo: Mobic | Igama elijwayelekile: Celecoxib Igama lomkhiqizo: Celebrex |
| Izidakamizwa zingena ngaziphi izinhlobo? | Ithebhulethi yomlomo Ama-capsules omlomo Ithebhulethi ehlakazeka ngomlomo Ukumiswa ngomlomo | Ama-capsules omlomo |
| Uyini umthamo ojwayelekile? | 7.5 mg kanye ngosuku | I-200 mg kanye ngosuku noma i-100 mg kabili ngosuku |
| Yelashwa isikhathi esingakanani? | Ukusetshenziswa kwesikhashana noma kwesikhathi eside ngokuya ngemiyalo kadokotela wakho | Ukusetshenziswa kwesikhashana noma kwesikhathi eside ngokuya ngemiyalo kadokotela wakho |
| Ubani ovame ukusebenzisa umuthi? | Abantu abadala nezingane ezingaphezu kweminyaka emibili ubudala futhi banesisindo esingu-132 lbs (60 kg) noma ngaphezulu | Abantu abadala nezingane ezingaphezu kweminyaka emibili ubudala futhi banesisindo esingama-22 lbs (10 kg) noma ngaphezulu |
Ufuna intengo engcono kuMeloxicam?
Bhalisela izexwayiso zentengo ye-Meloxicam bese uthola ukuthi intengo ishintsha nini!
Thola izexwayiso zentengo
Izimo eziphathwe yi-Meloxicam ne-Celebrex
IMeloxicam ngumuthi ojwayelekile ovunyelwe yi-FDA wokwelapha i-osteoarthritis ne-rheumatoid arthritis. Ingaphinde ilaphe i-juvenile rheumatoid arthritis, uhlobo lokuvuvukala okuzenzakalelayo, ezinganeni ezineminyaka emibili kuya kwengu-17 ubudala ezinesisindo esingamakhilogremu ayi-132 (60 kg) noma ngaphezulu.
I-Celebrex (i-celecoxib) igama lomuthi i-FDA evunyelwe ukwelapha i-osteoarthritis ne-rheumatoid arthritis. Iphinde iphathe i-juvenile rheumatoid arthritis ezinganeni ezineminyaka engu-2 kuya kwengu-17 ubudala enesisindo esingama-22 lbs (10 kg) noma ngaphezulu. I-Celebrex nayo ingaphatha i-arthritis yomgogodla (i-ankylosing spondylitis), ubuhlungu be-cramp yokuya esikhathini (i-dysmenorrhea eyinhloko), nobuhlungu obujwayelekile obujwayelekile.
| Isimo | UMeloxicam | UCelebrex |
| I-osteoarthritis | Yebo | Yebo |
| Isifo samathambo | Yebo | Yebo |
| Isifo samathambo sentsha | Yebo | Yebo |
| I-Ankylosing spondylitis | Akunjalo | Yebo |
| I-dysmenorrhea eyinhloko | Akunjalo | Yebo |
| Ubuhlungu obukhulu | Akunjalo | Yebo |
Ngabe iMeloxicam noma iCelebrex isebenza kangcono?
IMeloxicam neCelebrex zombili ziyasebenza ekwehliseni ukuvuvukala, ubuhlungu nokuvuvukala uma kuhlotshaniswa nesifo samathambo. Ziyi-COX-2 inhibitor NSAID enciphisa ukukhiqizwa kwama-prostaglandins ngokuvimba i-cyclooxygenase (COX-2) enzyme. Ngoba wonke umuntu uphendula imithi ngokungafani, umehluko wabo ekusebenzeni kuyehluka phakathi kwabantu.
Kokukodwa ukubuyekeza , Ama-NSAID akhethiwe we-COX-2 afana ne-meloxicam ne-celecoxib atholakale esebenza ngokulinganayo njengama-NSAID angakhethi afana ne-ibuprofen ne-naproxen ye-arthritis. Kodwa-ke, eminye imiphumela ikhombisile ukuthi i-meloxicam ingahle ingasebenzi kahle kwezinye izimo. Ama-NSAID akhethiwe e-COX-2 atholakale anemiphumela emibi kakhulu yamathumbu (GI) efana nezilonda zesisu uma kuqhathaniswa namanye ama-NSAID.
Enye funda kukhombisile ukuthi, ngenkathi izidakamizwa ezinjenge-celecoxib ne-meloxicam zinobungozi obuncane bezehlakalo ezimbi ze-GI, zingaba nengozi eyengeziwe yemiphumela emibi yenhliziyo noma yenhliziyo. Kodwa-ke, wonke ama-NSAID, ngokuvamile, atholakale enengozi yenhliziyo futhi kufanele athathwe kuphela ngezeluleko ezifanele zezokwelapha.
Ufuna intengo engcono kakhulu kuCelebrex?
Bhalisela izexwayiso zentengo yeCelebrex bese uthola ukuthi intengo ishintsha nini!
Thola izexwayiso zentengo
Ukuhlanganisa kanye nokuqhathanisa izindleko kwe-Meloxicam vs. Celebrex
IMeloxicam ngumuthi ojwayelekile ohlanganiswa yiMedicare nezinhlelo eziningi zomshuwalense. Izindleko ezijwayelekile zokuthengisa ze-meloxicam cishe zingama- $ 35. Ngokusebenzisa ikhadi lesaphulelo le-Single Care, ungonga okuningi bese ukhokha cishe u- $ 13 ngenani elifanayo.
Thola ikhadi lesaphulelo le-SingleCare
ICelebrex ngumuthi wegama lomkhiqizo otholakala kunguqulo ejwayelekile embozwe ngabakwaMedicare nezinhlelo eziningi zomshuwalense. Izindleko ezijwayelekile zokuthengisa zegama lomkhiqizo uCelebrex cishe zingama- $ 230. Ngekhadi lesaphulelo le-Single Care, ungonga kwi-celecoxib ejwayelekile bese ukhokha cishe u- $ 120 ngenani elifanayo.
| UMeloxicam | UCelebrex | |
| Ngokuvamile embozwe umshwalense? | Yebo | Yebo |
| Imbozwe ngokujwayelekile yi-Medicare? | Yebo | Yebo |
| Umthamo ojwayelekile | 7.5 mg amaphilisi (inani elingu-14) | Ama-50 mg capsules (inani lama-60) |
| I-Medicare copay ejwayelekile | Kuya ngecebo lakho lomshuwalense | Kuya ngecebo lakho lomshuwalense |
| Izindleko ze-SingleCare | $ 13 | $ 120 |
Imiphumela emibi ejwayelekile ye-Meloxicam ne-Celebrex
IMeloxicam neCelebrex babelana ngokufanayo okuqhamuka uma udla imishanguzo . Womabili ama-NSAID angadala imiphumela emibi efana nobuhlungu besisu, isifo sohudo, isicanucanu, ukugaya ukudla, kanye nokuqothuka (igesi). Yomibili le mithi ingadala ikhanda, isiyezi, izinhlungu emuva, nezimpawu ezifana nomkhuhlane phakathi kwabanye.
Imiphumela emibi kakhulu ingafaka ukushintshwa kwengcindezi yegazi, i-arrhythmias yenhliziyo, nokusebenza kwesibindi okungakhubazekile. Yize kungavamile, ukusabela kokungezwani komzimba nakho kungenzeka futhi kufaka phakathi ukuphefumula okunenkinga, ubuhlungu besifuba, ukuvuvukala nezindlwana.
| UMeloxicam | UCelebrex | |||
| Imiphumela emibi | Kusebenza? | Imvamisa | Kusebenza? | Imvamisa |
| Ubuhlungu besisu | Yebo | 1.9% | Yebo | 4.1% |
| Ubuhlungu bekhanda | Yebo | 7.8% | Yebo | 15.8% |
| Uhudo | Yebo | 7.8% | Yebo | 5.6% |
| Ukugaya ukudla | Yebo | 4.5% | Yebo | 8.8% |
| Ukuqhuma kwesisu | Yebo | 3.2% | Yebo | 2.2% |
| Isicanucanu | Yebo | 3.9% | Yebo | 3.5% |
| I-Edema (i-fluid buildup ezingalweni) | Yebo | 1.9% | Yebo | 2.1% |
| Umphimbo obuhlungu | Yebo | 0.6% | Yebo | 2.3% |
| Izimpawu ezinjengomkhuhlane | Yebo | 4.5% | Yebo | 0.1-1.9% |
| Ukutheleleka okuphezulu okuphefumulayo | Yebo | 1.9% | Yebo | 8.1% |
| Ukuqhuma kwesikhumba | Yebo | 2.6% | Yebo | 2.2% |
| Isiyezi | Yebo | 3.2% | Yebo | 2.0% |
| Ukuhlungu obusemhlane | Yebo | 3.0% | Yebo | 2.8% |
| Ukuqwasha | Yebo | 3.6% | Yebo | 2.3% |
Umthombo: DailyMed ( UMeloxicam ), IDailyMed ( UCelebrex )
Ukusebenzisana kwezidakamizwa kwe-Meloxicam vs. Celebrex
Kokubili i-meloxicam neCelebrex kungasebenzisana nabanciphisi begazi abanjenge-aspirin yedosi ephansi, i-warfarin nezinye izidakamizwa. Ukuthatha le mithi ndawonye kungandisa ingozi yokuphuma kwegazi kanye nezilonda zesisu.
IMeloxicam neCelebrex nazo zingasebenzisana nama-diuretics nemithi ethile yomfutho wegazi efana ne-ACE inhibitors, ama-angiotensin receptor blockers (ARBs), kanye ne-beta blockers. Ukuthatha le mithi ndawonye kungakhuphula ubungozi bezinkinga zezinso.
IMeloxicam neCelebrex nazo ziyaxhumana ne-lithium, methotrexate, ne-cyclosporine. Ukuthatha le mithi ndawonye kungaholela ekwandeni kobuthi.
Kubalulekile ukuxoxa ngayo yonke imithi ongayiphuza nodokotela wakho ngaphambi kokuthatha i-NSAID efana ne-meloxicam noma iCelebrex.
| Izidakamizwa | Isigaba Sezidakamizwa | UMeloxicam | UCelebrex |
| I-Aspirin | I-Antiplatelet | Yebo | Yebo |
| I-Warfarin | I-Anticoagulant | Yebo | Yebo |
| I-Escitalopram I-Fluoxetine I-Paroxetine Sertraline I-Citalopram | I-antidepressant ekhethiwe ye-serotonin reuptake inhibitor (SSRI) | Yebo | Yebo |
| I-Venlafaxine I-Milnacipran I-Duloxetine I-Desvenlafaxine | ISerotonin-norepinephrine reuptake inhibitor (SNRI) i-antidepressant | Yebo | Yebo |
| I-Lisinopril Enalapril I-Benazepril URamipril | I-Angiotensin-converting enzyme (ACE) inhibitors | Yebo | Yebo |
| ILosartan Valsartan I-Irbesartan I-Candesartan | Ama-Angiotensin receptor blockers (ama-ARB) | Yebo | Yebo |
| I-Propranolol I-Metoprolol I-Atenolol I-Bisoprolol | Ama-beta blockers | Yebo | Yebo |
| UFurosemide I-Hydrochlorothiazide | Izidakamizwa | Yebo | Yebo |
| ILithium | Isimisi sokuqina | Yebo | Yebo |
| IMethotrexate | I-Antimetabolite | Yebo | Yebo |
| ICyclosporine | I-Immunosuppressant | Yebo | Yebo |
| Diflunisal Salsalate | Ama-salicylates | Yebo | Yebo |
| I-Pemetrexed | Umenzeli we-antineoplastic | Yebo | Yebo |
* Lokhu kungenzeka kungabi uhlu oluphelele lwako konke ukuhlangana kwezidakamizwa okungenzeka. Xhumana nodokotela ngayo yonke imithi ongayiphuza g.
Izexwayiso ze-Meloxicam ne-Celebrex
UMeloxicam noCelebrex bobabili banezexwayiso kumalebula abo ezidakamizwa akhombisa ubungozi obukhulu besisu (GI) nemiphumela yenhliziyo. Lawa ma-NSAID angakhuphula ubungozi bemicimbi ye-GI efana nezilonda zesisu noma ukopha esiswini noma emathunjini. Zingakhuphula nengozi yokuhlaselwa yisifo senhliziyo nokushaywa unhlangothi. Uma unomlando we-high blood pressure, isifo senhliziyo, noma ezinye izimo, ungaba sengozini enkulu.
Kokubili i-meloxicam neCelebrex akunconywa kulabo abahlinzwe ngomthambo we-coronary bypass graft (CABG).
IMeloxicam neCelebrex kufanele zibhekwe kulabo abanezinkinga zezinso noma zesibindi ngoba bangenza lezi zinkinga zibe zimbi kakhulu. Lawa ma-NSAID angaphinde abe sibi kakhulu ngokuhlobene nesifuba somoya nokuzwela kwe-aspirin.
Akunconywa ukusebenzisa ama-NSAID ngenkathi ukhulelwe.
Imibuzo ebuzwa njalo nge-Meloxicam vs. Celebrex
Yini iMeloxicam?
IMeloxicam ngumuthi ojwayelekile we-NSAID ongelapha ukuvuvukala, ubuhlungu nokuvuvukala kwesifo samathambo. Imvamisa kuthathwa kanye nsuku zonke kuye ngemibhalo kadokotela wakho. Njenge-COX-2 inhibitor ekhethiwe, ingaba nengozi ephansi yezilonda zesisu uma iqhathaniswa namanye ama-NSAID.
Kuyini iCelebrex?
I-Celebrex yigama lomkhiqizo le-celecoxib, i-NSAID elapha isifo samathambo. Ingaphinde ilaphe i-arthritis yomgogodla kanye nezilonda zokuya esikhathini. I-Celebrex ithathwa kanye noma kabili nsuku zonke. Kungokwesigaba sama-NSAID abizwa nge-COX-2 ama-NSAID akhethiwe.
Ngabe iMeloxicam neCelebrex ziyefana?
IMeloxicam neCelebrex basekilasini elilodwa lemithi ebizwa ngama-NSAID. Noma kunjalo, azifani. Kunokusetshenziswa okuhlukile futhi kungathathwa ngendlela ehlukile kuye ngesimo esiphathwayo.
Ngabe iMeloxicam noma iCelebrex ingcono?
IMeloxicam neCelebrex zombili ziyasebenza ngokuya ngokusetshenziswa kwazo. I-Meloxicam ingancanyelwa umthamo wayo wansuku zonke. I-Celebrex ingakhethwa kumuntu one-ankylosing spondylitis noma amajaqamba okuya esikhathini.
Ngingayisebenzisa iMeloxicam noma iCelebrex ngikhulelwe?
IMeloxicam neCelebrex kufanele kugwenywe kwabesifazane abakhulelwe. Ukuthatha ama-NSAID ngesikhathi se-trimester yesithathu kungakhuphula ubungozi bezinkinga zenhliziyo enganeni.
Ngingayisebenzisa iMeloxicam noma iCelebrex ngotshwala?
Cha akunconywa ukusebenzisa i-meloxicam noma iCelebrex ngotshwala. Ukwenza kanjalo kungakhuphula ingozi yokuphuma kwegazi noma izilonda zesisu.
Ingabe iCelebrex ibangela ukuzuza kwesisindo?
Ukuzuza kwesisindo kungumphumela ongathandeki kodwa ongaba khona weCelebrex. Kungenzeka ngo-0.1% kuya ku-1.9% walabo abathatha iCelebrex, ngokusho kwelebula lezidakamizwa.
Ngabe iCelebrex isebenza ngokushesha?
ICelebrex iqala ukusebenza njengoba umuthi ufakwa emzimbeni. Ukuncela kungenzeka ngokushesha kepha yize kungathatha amasonto ambalwa ukuthatha i-Celebrex ngokungaguquki ukuthola izinzuzo ezigcwele.
