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Funda ukubona izimpawu zesifo se-serotonin

Imfundo Yezempilo

Ake sithi uthatha incwadi kadokotela i-antidepressant , njenge I-Paxil (paroxetine), nsuku zonke. Uzizwa u migraine iza, ngakho-ke umba edilowini ufuna i Imitrex (sumatriptan) ithebhulethi.

Noma, esinye isimo esivamile — uthatha i-antidepressant ICymbalta (duloxetine), futhi uzwa amakhaza nokukhwehlela kuza. Ufinyelela ibhodlela le- I-Robitussin-DM ukwelapha izimpawu zakho.

Lezi zinto zibukeka zingenabungozi, akunjalo? Cabanga futhi. Lezi zimo zokuxuba imishanguzo zingadala into ebizwa nge-serotonin syndrome, engabeka impilo yakho engcupheni.

ISerotonin iyi-neurotransmitter. Ukucindezeleka kuvame ukuhlotshaniswa namazinga aphansi we-serotonin. Izindlela zokwelashwa eziningi ze- ukudana siza ukukhulisa amazinga e-serotonin. Eminye imishanguzo (njengemithi ethile ye-migraine, imithi yezinhlungu, ukucindezela ukukhwehlela, kanye nezithako zokudla) nakho kungakhuphula amazinga e-serotonin.

Uma uthatha umuthi owandisa i-serotonin, ungahle uzizwe ulungile. Kepha, i-serotonin eningi kakhulu kusuka kumthamo ophakeme kakhulu, noma ekuthatheni imithi emibili noma ngaphezulu eyandisa amazinga e-serotonin, ingadala i-serotonin syndrome.

Yini i-serotonin syndrome?

I-Serotonin syndrome yenzeka lapho ikhona i-serotonin eningi kakhulu kusistimu yakho. Uthola kanjani i-serotonin eningi emzimbeni wakho?

I-Serotonin syndrome ingenzeka lapho othile:

Ithatha imithi engaphezu kweyodwa ethinta amazinga e-serotonin
Iqala noma inyuse umthamo womuthi owandisa i-serotonin
Ithatha umuthi omningi owandisa i-serotonin (ngengozi noma ngenhloso)

Uma ishiywe ingalashwa, imiphumela ingaba mibi kakhulu.

Imiphi imishanguzo engadala i-serotonin syndrome?

Imithi elandelayo inyusa amazinga e-serotonin futhi ingabandakanyeka ezimweni ze-serotonin syndrome. I-Serotonin syndrome kungenzeka kakhulu ukuthi yenzeke uma uthatha inhlanganisela yezidakamizwa ezimbili noma ngaphezulu.

Izidakamizwa ze-SSRI: Ama-SSRIs (ama-serotonin reuptake inhibitors akhethiwe) yizidakamizwa ezivame kakhulu ukubandakanyeka ku-serotonin syndrome. Kubandakanya i-Prozac (i-fluoxetine), i-Paxil (i-paroxetine), i-Zoloft (i-sertraline), i-Celexa (i-citalopram), i-Lexapro (i-escitalopram), i-Luvox (i-fluvoxamine) ne-Trintellix.
Izidakamizwa ze-SNRI: Ama-SNRIs (serotonin-norepinephrine reuptake inhibitors) afaka phakathi iCymbalta (duloxetine), i-Effexor (venlafaxine), nePristiq (desvenlafaxine).
Amanye ama-anti-depressants: Imithi ye-Tricyclic antidepressant (amitriptyline, nortriptyline), bupropion, trazodone, MAOIs (monoamine oxidase inhibitors)
Ama-opioid painkillers : njengePercocet, i-oxycodone, i-OxyContin, i-Ultram (i-tramadol), i-Demerol (i-meperidine), i-fentanyl, i-Vicodin
Ukukhwehlela ukucindezela: Noma imuphi umuthi okhwehlela / obandayo oqukethe i-dextromethorphan, efana neRobitussin-DM, i-promethazine DM, iDelsym, iMucinex-DM
Imithi ye-Migraine: Ama-Triptans afana ne-Amerge (naratriptan), Imitrex (sumatriptan), Relpax (eletriptan), iZomig (zolmitriptan), Axert (almotriptan)
Eminye imithi kadokotela: I-Metoclopramide, i-ondansetron, i-linezolid
Izithako zemithi: Ginseng, iSt John's Wort
Izidakamizwa ezingekho emthethweni: I-Ecstasy, i-LSD, i-cocaine

Ivamile kangakanani i-serotonin syndrome?

Ochwepheshe Angiqiniseki yenani lamacala we-serotonin syndrome. Lokhu kungenxa yokuthi amacala amancane angahle anganakwa noma anganakwa. Amacala abucayi angabangelwa kwesinye isizathu. Siyazi ukuthi i-serotonin syndrome ingenzeka kubantu banoma yimuphi ubudala, futhi njengoba ukusetshenziswa kwe-antidepressant kuyanda, amacala e-serotonin syndrome ayanda.

Ziyini izimpawu ze-serotonin syndrome?

Izimpawu zesifo se-Serotonin zikhula ngokushesha ngemuva kokuthatha umuthi wokuncipha — amacala angama-60% enzeka kungakapheli amahora ayisithupha. Iningi leziguli linezimpawu zingakapheli amahora angama-24.

Izimpawu zingahluka kusuka kokuncane kuya ekusongeleni impilo futhi zingafaka:

Ukuyaluza
Ukukhathazeka
Ukungahlaliseki
Ukushintsha kwemizwelo / ukuguquka kwesimo sengqondo
Ukudideka noma ukudideka
Ukulahleka kokuhlanganiswa kwemisipha
Ukujuluka noma ukuqhaqhazela
Isikhumba esigcwele
Imfiva
I-Hyperthermia (ukushisa ngokweqile)
Ukunyuka kwenhliziyo, umfutho wegazi ophakeme
Isicanucanu, ukuhlanza, isifo sohudo
Ukuthuthumela
Ukuqina kwemisipha, ukuqina kwemisipha, noma imisipha, ikakhulukazi emilenzeni
Izimo ezingasebenzi kahle
Abafundi abahlanzekile

Izimpawu ezinzima kakhulu ze-serotonin syndrome zifaka phakathi umkhuhlane omkhulu, ukuquleka, ukushaya kwenhliziyo okungajwayelekile, nokuquleka.

OKUSHIWO: Yikuphi ukushisa komzimba okubhekwa njengomkhuhlane?

Okufanele ukwenze uma ucabanga ukuthi une-serotonin syndrome

Uma uthatha umuthi othinta amazinga e-serotonin futhi uhlangabezana nanoma yiziphi kulezi zimpawu ezingenhla, funa ukwelashwa ngokushesha esikhungweni sokunakekelwa esiphuthumayo noma egumbini labezimo eziphuthumayo. Amacala abucayi asongela impilo futhi angathuthuka ngokushesha aze afe.

Umhlinzeki wezokunakekelwa kwezempilo ovame ukumbona angahlola i-serotonin syndrome emtholampilo, ngokuhlola izimpawu zakho nangokubuyekeza imithi oyiphuzayo (kokubili incwadi kadokotela kanye ne-counter-the-counter). Abanye odokotela basebenzisa i- Indlela Yokuzingela I-Hunter Serotonin ukusiza ekutholeni i-serotonin syndrome.

Yini ukwelashwa kwe-serotonin syndrome?

Funa ukwelashwa ngokushesha kwezimpawu ze-serotonin syndrome.
Uma unezimpawu ezincane, umhlinzeki wakho wezokunakekelwa kwempilo cishe uzokweluleka ukuthi uyeke umuthi noma izidakamizwa ezidala ukusabela ngokushesha. Uma unezimpawu eziningi eziphathelene noma ezinzima, kufanele welashwe futhi ubhekwe esibhedlela. Ukwelashwa kwe-serotonin syndrome kuya ngezimpawu nobukhulu bezimpawu.

Eminye imithi yayijwayele phatha izimpawu faka:

I-Benzodiazepines (njenge mzingisi ) ukusiza ukuyaluza, ukuquleka, nokuqina
ICyproheptadine ukuvimba ukukhiqizwa kwe-serotonin
Imithi yokwehlisa isilinganiso senhliziyo yakho noma umfutho wegazi (noma phakamisa umfutho wegazi lakho uma uphansi kakhulu)

Ungadinga futhi uketshezi lwe-IV lokwehla kwamanzi emzimbeni nomkhuhlane, noma i-oxygen eyengeziwe.

Ihlala isikhathi esingakanani i-serotonin syndrome?

Ubude besikhathi ongathola ngaso i-serotonin syndrome buyahlukahluka. Uma unesimo esincane se-serotonin syndrome, ungazizwa ungcono kungakapheli usuku olulodwa noma ezintathu. Amanye amacala angathatha amasonto ambalwa ukuthi ahambe, kuya ngokuthi imiphi imithi (imithi) ebangele ukusabela nokuthi imithi (i) ihlala isikhathi esingakanani emzimbeni wakho.

Uchwepheshe Wezomndeni WaseMelika uyachaza ukuthi wena can ululame ngokuphelele kwi-serotonin syndrome, inqobo nje uma ibonwa ngokushesha futhi nezinkinga zilawulwa kahle.

Ingabe i-serotonin syndrome ingadala umonakalo wesikhathi eside?

I- izindaba ezimnandi ngukuthi cishe kuzo zonke izimo, uma lesi sifo sibanjwa kusenesikhathi, akumele kube khona imiphumela emibi yesikhathi eside, ngokusho kongoti besibhedlela.

Ngenxa yokubaluleka kokwelapha i-serotonin syndrome kusenesikhathi, kubalulekile ukufuna ukwelashwa ngokushesha uma unezimpawu.

Ungayigwema kanjani i-serotonin syndrome

Noma ngubani othatha umuthi owandisa i-serotonin usengozini ye-serotonin syndrome.

Ukuze uphephe, thola yonke imithi yakho ekhemisi elilodwa. Ngale ndlela, usokhemisi angakwazi wena futhi abe nohlu lwakho oluphelele lwemithi ukuze ahlole ukuxhumana kwezidakamizwa.
Uma unezinguquko ohlelweni lwemithi yakho, njengokuqala umuthi omusha, ngaso sonke isikhathi thintana nosokhemisi wakho ukuze uqiniseke ukuthi awuphindi kabili ku-serotonin.
Uma uthatha imishanguzo eyandisa i-serotonin, qaphela izimpawu ze-serotonin syndrome. Funa ukwelashwa ngokushesha uma unezimpawu.
Uma udinga umuthi obandayo / wokukhwehlela futhi usuvele uthatha umuthi owandisa amazinga e-serotonin, hlola izithako, futhi ugweme i-dextromethorphan. Usokhemisi wakho angakusiza ukhethe umkhiqizo ofanele.
Imithi eminingi ehlukene ithinta amazinga e-serotonin. Ukuguqulwa kwesilinganiso noma ukuhlanganiswa kwemithi emibili eyandisa i-serotonin kungadala i-serotonin syndrome, engabeka impilo engcupheni.

Njalo hlola umhlinzeki wakho wezokunakekelwa kwempilo ukuze uqiniseke ukuthi imishanguzo oyiphuzayo iyahambisana.