Ucansi kuma-anti-depressants: Ukuhlola imiphumela emibi yezocansi yama-SSRI

Izindaba

Esikhathini sesikhathi seminyaka engu-15, inani labantu baseMelika abathatha imishanguzo yokulwa nezidakamizwa lenyuke cishe ngama-65%, lenyuka lisuka kubantu abangaphansi kwabangu-8% base-U.S. cishe i-13% . Ucwaningo luphakamisa ukuthi abantu abaqala ukuthatha imishanguzo yokusiza ekulawuleni impilo yabo yengqondo kwesinye isikhathi bayakuthola abakwazi ukuyeka —Naphezu kwemiphumela emibi engaba namandla.

I-serotonin reuptake inhibitors ekhethiwe ( Ama-SSRIs ) ziphakathi kwezifo zokulwa nokucindezelwa okujwayeleke kakhulu, kanti ngenkathi zingathathwa njengeziluthayo, imiphumela emibi yama-SSRI ingabandakanya ukozela, isicanucanu, ukuqwasha, ukungahlaliseki nokusebenza kocansi okungasebenzi kahle.

Ukubhekisisa kahle imithelela yama-anti-depressants efana nama-SSRI kubantu baseMelika kanye nezikhathi zabo ezisondelene kakhulu, sihlolisise abantu abangu-1 000 abasanda kuphathwa ngama-SSRI noma ama-non-SSRI antidepressants. Qhubeka ufunde njengoba sihlola ukuthi bangaki abasebenzisi abaziyo ngemiphumela emibi yezocansi yama-SSRI nokuthi bangaki abakholelwa ukuthi le miphumela engemihle ibalulekile.

Imithi yokwesaba-nemiphumela yako emibi

Ukudangala kuba yimbangela ehamba phambili yokukhubazeka emhlabeni wonke kubantu abaneminyaka engu-15-44, ngokusho kwe-Anxiety and Depression Association of America. Phakathi kwezifo zengqondo ezivame kakhulu kulo lonke elase-U.S., Cishe 7% wabantu abadala ube nokudangala. Izimpawu zingafaka imizwa yokudabuka, ukuqwasha, ukukhathala, amasosha omzimba abuthakathaka, kanye a ingozi ephezulu yokuhlaselwa yisifo senhliziyo .

Ama-serotonin reuptake inhibitors akhethiwe (ama-SSRIs) yiwona-antidepressants abekiwe kakhulu eMelika. Ngokwandisa amazinga e-serotonin ebuchosheni, ama-SSRI kwesinye isikhathi anqunyiwe ukusiza ukuphatha ezinye izimo, kufaka phakathi ukukhathazeka . Ama-SSRI awekho ngaphandle kwemiphumela emibi, noma kunjalo. Kuya ku Abantu abangama-73% abathatha ama-SSRI uhlangabezana nohlobo oluthile lomthelela wezocansi kusuka kulesi sigaba semithi. Ngenkathi le miphumela emibi ingancipha ngemuva kwamasonto ambalwa kuma-SSRI, ezinye iziguli kungenzeka zingakubekezeleli ukwelashwa.

Ukuqwashiswa komthelela wezocansi nama-SSRI

Abaphenyi bayaqonda ukuthi ama-SSRI abonakala enesandla ekungasebenzi kahle kwezocansi, kepha futhi bayavuma ukuthi ukukala umthelela weqiniso we-anti-depressants ku ukushayela ucansi nokusebenza kungaba nzima. Kwezinye izimo, ukungasebenzi ngokocansi kungandulela ukwethulwa kwama-SSRI njengokwelashwa (ukungasebenzi ngokocansi nakho kuyisibonakaliso sokucindezeleka), noma kungahle kuhlobene nesinye isimo somzimba. Kwezinye iziguli, zonke izigaba zokusondelana, ezisukela esifisweni kuya ekuzijabuliseni ngokocansi kanye ne-orgasm, zingavinjelwa ukusetshenziswa kwama-SSRI.

Sithole abantu abangaphezu kuka-82% abanomlando wokuphuza imishanguzo yokuxineka bebeyazi imiphumela emibi yocansi. Noma kunjalo, abaningi bebesebumnyameni maqondana nokuthi imithi yabo iyithinta kanjani i-sex drive yabo nokusebenza kwabo. Abantu abangaphezu kuka-12% abahlangabezana nemiphumela emibi kwezocansi kuma-anti-depressants bebengazi ukuthi ukwelashwa kwabo kungadala ukungasebenzi kahle, kulandelwe ngabantu abacishe babe ngama-47% abangenakho ukwehla okubikiwe ekusebenzeni kocansi.

Ukubaluleka kokuxhumana nodokotela nesiguli

Ukuxhumana phakathi kodokotela, iziguli, nabasebenzi basehhovisi kuyingxenye ebaluleke kakhulu yokunakekelwa kwezempilo. Amaphutha okuxhumana, angaba yingozi uma engabulali, avela ekungazini, izingxoxo ezingabhalwanga, noma izingxoxo ezingabanjwanga ngokuphelele. Ezimweni eziningi, ukuxhumana kabi noma ukuxhumana okungabanjwanga kuholela emaphutheni we ubukhali obuphakathi noma obuphakeme .

Cishe abesifazane abangama-50% nabesilisa abangaphezu kwama-28% bakhombisile ukuthi odokotela babo abachazanga nakancane ngemiphumela emibi yezocansi yama-SSRI.

Ngenkathi abesifazane bebenamathuba amaningi kunamadoda okuthi bangatholi ncazelo kodokotela babo ngamathuba okukhubazeka ngokocansi, abesifazane nabo bebengaphansi amathuba okuthi baphakamise ukukhathazeka okufanayo kodokotela babo (26%) noma ukukhathazeka kwabo kuthathwe ngokungathi sína odokotela babo (63%) . Abantu abanomlando wokusetshenziswa kwe-antidepressant babehlala benamahloni kakhulu noma bengakhululeki ukukhuluma ngemiphumela emibi yezocansi yama-SSRI nodokotela, kulandele abantu ababona izinzuzo zidlula umthelela omubi empilweni yabo yezocansi.

Ubungozi nomvuzo: Imiphumela emibi yezocansi yama-SSRI

Amaphesenti angama-73 abesifazane kanye nabesilisa abacishe babe ngama-63% bavumile ukuthi bazizwa benesifiso esinciphile socansi ngenkathi bethatha ama-SSRI, kanti cishe abesifazane abangama-41% nabesilisa abangama-35% bathe balahlekelwe isifiso sobulili ngokuphelele. Yize ukuguquguquka kwesifiso sobulili noma ukusondelana kuyinto ejwayelekile, ochwepheshe baxwayisa ngokuthi uma leso sifiso siphela ngokuphelele, singaba nomthelela omubi ebudlelwaneni nasezingeni lempilo. Ikakhulukazi kwabesifazane, abacwaningi basikisela ukuthi akuyona into engavamile i-libido ephansi kanye nokudangala kokuhlangana .

Abesifazane kuma-SSRI babenamathuba amaningi okubika amandla ancishisiwe e-orgasm, ukungakwazi ukwenza i-orgasm, ukungakwazi ukuvuswa, nobuhlungu ngesikhathi socansi. Noma kunjalo, lapho iziguli ze-SSRI zisebenza kahle kakhulu, zazikhathazeka kakhulu ngemiphumela emibi yesidakamizwa. Uma kuqhathaniswa nabantu abacishe babe ngu-32% abakholelwa ukuthi ama-SSRIs awasebenzanga nhlobo, iziguli ezingama-79% ezithola ukuthi ama-SSRIs asebenza kakhulu kakhulu bezimisele ukwamukela imiphumela emibi njengokufanele.

Umthelela wama-anti-depressants ebudlelwaneni bezothando

Ama-SSRI angaba yi-antidepressant ebekiwe kakhulu, kepha akuyona ukuphela kwendlela yokwelashwa etholakalayo. I-Serotonin ne-norepinephrine reuptake inhibitors (SNRIs), ifomu elisha le- umuthi olwa nokucindezelwa , Futhi i-norepinephrine ne-dopamine reuptake inhibitors (i-NDRIs) nayo imele izinketho zokwelashwa ezingaba khona. Amanye ama-anti-depressants angathinti i-libido njengoba amanye ama-SSRI efaka: I-Wellbutrin ( bupropion ) kanye trazodone .

Abantu abanomlando wokusetshenziswa kwe-anti-depressant babenamathuba amaningi okubika ukusondelana kocansi okuthuthukile kunalawo angawona ama-SSRIs. Cishe abesifazane abangama-60% nabesilisa abacishe babe ngama-54% kuma-SSRIs bathi kulimaza impilo yabo yezocansi, kulandelwa abesifazane abangama-30% kanye nabesilisa abangama-26% kuma-SSRI obudlelwano babo kungenzeka ukuthi buhlukane ngenxa yemithi yabo yokulwa nengcindezi.

Izindlela zokunciphisa izimpawu ze-SSRI

Ucwaningo lukhomba ukuhlangana okuphezulu phakathi kwama-anti-depressants kanye nokungasebenzi kahle kwezocansi, kepha ezinye izixazululo zivumela umthelela omuhle kakhulu we-anti-depressants. Ukweqiwa okuphezulu kuvame ukuholela ku ingozi ephezulu yemiphumela emibi yezocansi , ngakho ukukhuluma nodokotela mayelana nokwehlisa umthamo kungasiza. Ukuthatha ama-anti-depressants ngesikhathi esithile sosuku nakho kungasiza ukwehlisa ingcindezi kwezocansi.

Noma kunjalo, abantu abaningi bakhethe ukungenzi lutho ngomphumela wama-SSRI empilweni yabo yezocansi. Amaphesenti angama-50 abesifazane kanye nabesilisa abangama-42% abazami ukunqoba imiphumela emibi yezocansi ye-anti-depressants yabo, futhi kuphela i-14% yabesifazane kanye ne-19% yabesilisa ababike ukuthi bakhuluma nodokotela.

Abanye abantu bayishintshe ngokuphelele imishanguzo, kanti abanye bashintshe imithamo yabo, bafaka amathoyizi ocansi egumbini lokulala, noma imisebenzi ehleliwe yezocansi.

Ukubaluleka kokuxhumana phakathi kwabalingani abathandanayo

Kungazwakala sengathi kufanele ukhethe phakathi kokuqhubeka nokulwa nezidakamizwa noma ube nokuphila kocansi okungcono. Kodwa-ke, kungenzeka ukuthi kutholakale ibhalansi phakathi kokwelapha ukucindezeleka (noma ukukhathazeka) ngaphandle kwemiphumela emibi engazinzile.

Ochwepheshe batusa ukwanda ukuxhumana phakathi kwabalingani bezothando ukugwema ukucindezeleka okungadingekile kanye nokungezwani. Ukuzivumelanisa nempilo kuma-anti-depressants kungaba nzima, futhi wonke umuntu ubaphendula ngokuhlukile. Ukwakha ingxoxo evulekile phakathi kwezithandani kungasiza ekuqedeni ukuhlukumezeka okwengeziwe okungokomzwelo.

Amaphesenti angama-84 emibhangqwana eshadile akhulume ngemiphumela emibi yezocansi ebangelwa ama-anti-depressants, alandelwa ngabantu abangu-81% ebudlelwaneni. Ngenkathi abantu abangama-68% okwamanje abahlukanisile noma abahlukanisile nabo bevulela abalingani babo ngaleso sikhathi, kuphela ama-66% abantu abangashadile abelana ngamava abo kuma-SSRIs. Kulabo ababenethezekile ngokuvula ukukhathazeka kwabo ngokocansi, ngaphezu kuka-22% babika ukuthi basondela kakhulu kozakwethu, uma kuqhathaniswa no-10% kuphela abangazange bakhulume nomlingani wabo.

Imibono ngempilo yengqondo

Abantu ababenokuhlangenwe nakho komuntu siqu ngempilo kuma-anti-depressants nakuma-SSRI basinikeza imibono yabo yokuthi singabhekana kanjani nemiphumela emibi yocansi.

Njengoba ukwazi ukubona ezimpendulweni zabo, ukukhuluma ngesimo nokuveza imizwa yakho kwakuvame ukuba isenzo esinconywayo. Ngenkathi kungakhathaza noma kungakhululeki ekuqaleni, ukuvula mayelana nokuhlangenwe nakho kwakho kocansi njengoba omunye wenu eqala ukwelashwa kungasiza ukugwema ukudideka, ukucabanga kanye nemizwa elimele.

Ngokwengeziwe, abantu abaningi bakwamukele ukubaluleka kokuhlanganyela lokhu okuhlangenwe nakho nodokotela lapho behlangabezana nemiphumela emibi yezocansi.

Isiphetho

Abantu baseMelika abangaphezu kwezigidi eziyi-16 banokudangala, futhi iningi labo liphatha lesi sifo ngama-anti-depressants afaka ama-SSRI. Ngenkathi le mithi inganikeza ukukhululeka okudingeka kakhulu, abantu abaningi babika ukuthi banokungasebenzi kahle kwezocansi futhi banciphisa isifiso sobulili ngenxa yokwelashwa. Ngokuya ngocwaningo lwethu, kubonakala sengathi kunegebe ekuxhumaneni phakathi kodokotela neziguli mayelana nemvelo yale miphumela emibi yezocansi, ikakhulukazi kubantu besifazane.

Noma imuphi umuthi owusebenzisayo, izindleko akufanele zibe wumphumela wecala ongeziwe. Ngo- Okufanayo , inhloso yethu ukwenza ukonga kwimithi yakho kadokotela kube lula ngangokunokwenzeka. Sebenzisa iwebhusayithi yethu noma uhlelo lwakho lokusebenza ukuthola incwadi kadokotela, qhathanisa amanani, bese ulondoloza ekhemisi olithandayo.

Indlela yokusebenza

Nge-Mechanical Turk yase-Amazon, siqoqe izimpendulo ezivela kubahlanganyeli abangu-1,002 abasanda kwelashwa ngama-anti-depressants e-SSRI noma ama-non-SSRI antidepressants. Ama-60.3% wabahlanganyeli bethu ngabesifazane, kuthi ama-39.7% abesilisa. Abahlanganyeli babeneminyaka yobudala kusuka ku-18 kuye ku-71 nge-mean of 35.7 nokuphambuka okujwayelekile kwe-10.4. Abaphenduli ababengatholakali ukuthi banokudangala noma ababengakaze babhekane nemizwa yokudana bakhishwa kulolu cwaningo, ngaphezu kwalabo ababengazange belashwe ngemishanguzo.

Imininingwane esiyethula incike ekuzibikeni ngokwakho. Idatha ezizimele inezinkinga ezinjengememori ekhethiwe, isibonakude, isichasiso, nehaba. Izibonelo zedatha yokuzibika ethintekayo kulolu cwaningo umbiko ohlangothini olulodwa lomthelela wokulwa nokucindezelwa kokuguquguquka kobudlelwano, kanye nokuhlangenwe nakho ngemiphumela emibi. Akukho ukuhlolwa kwezibalo okwenziwe kule datha, ngakho-ke izimangalo ezibalwe ngenhla zisuselwa kuzindlela zodwa.