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Konke odinga ukukwazi nge-wort yaseSt

Konke odinga ukukwazi nge-wort yaseStUkuphila kahle

Isibungu iStisitshalo esinezimbali eziphuzi esikhula ezindaweni ezahlukahlukene e-United States nase-Europe. Eyaziwa nangokuthi i-hypericum perforatum noma i-klamath weed, amaGrikhi asendulo asebenzisa lesi sitshalo ukwelapha izifo ezahlukahlukene, kusuka ekulunyweni yizilwane kuya ekucindezelekeni. Izinzuzo zayo zanamuhla zingaphansi kwezindawo ezifanayo, kepha ukusebenza kwayo ngokwesayensi nokuphepha kuhlala kungavikelekile emphakathini wezokwelapha. Imiphumela emibi engahle ingaqondakali kabanzi.

I-St. John's wort ngokuyinhloko isebenza nge-hypericin ne-hyperforin, okuyizakhi ezimbili ezisebenza ngokwe-biologically ku-supplement okuye kwaboniswa ukuthi kunezici ezibalulekile zezokwelapha. Njenganoma isiphi isitshalo, kunamanye amakhemikhali amaningi akhona, kufaka phakathi i-flavonoids (i-quercetin, i-rutin, i-luteolin) nama-tannins, angaba nezinzuzo zezempilo ezizimele, kusho uHarrison Weed, MD, ongudokotela wezangaphakathi Isikhungo Sezokwelapha i-Ohio State University Wexner .



Wenzani wort waseSt. Ukusetshenziswa nezinzuzo

I-St. John's wort iyikhambi lemvelo elivame ukuthengiswa ngefomethi yethebhulethi noma ye-capsule noma njengesithako ezinhlizweni ezinhlobonhlobo zempilo kanye netiye. Izifo ezivame kakhulu ukuphatha iSt John's wort yilezi:



  • Ukucindezeleka okuncane
  • Izimpawu zokuya esikhathini
  • Izifo ezivuthayo
  • Ukusika okuncane nokusha

Njengokwengeza, akulawulwa yi-U.S. Food and Drug Administration (FDA) noma kuvunyelwe ukwelashwa noma iyiphi yale mibandela. Yize, kukhona ucwaningo oluthile olukhombisa ukusebenza kwalo.

Ukucindezeleka okuncane

Kokusetshenziswa okwaziwayo kweSt.John's wort, ukucindezelwa okucwaningisiswa kakhulu futhi okushiwo kakhulu. Iziguli ezinokudangala okuncane zikhonjisiwe ukuthi zizuze kakhulu ngaphezu kwe-placebo ne- [St. I-John's wort] isebenza kahle njenge-antidepressant ejwayelekile, kusho u-Erin Nance, MD, udokotela ohlinzayo wamathambo waseNew York City, ecaphuna Ukubuyekezwa kweCochrane's ukubuyekezwa okuhlelekile ngale ndaba, okubhekwa njengenye yezinto ezibanzi kakhulu. Ngenkathi izilingo zomtholampilo zokwelapha ukudangala okuncane zibonisa imiphumela emihle, uma kukhulunywa ngokwelapha ukucindezeleka okulingene, ukucindezeleka okukhulu, ukucindezeleka okukhulu, noma ukuphazamiseka kwengqondo okuguquguqukayo, iSt.



yini enhle phezu komuthi we-counter nausea?

I-hyperforin etholakala eSt. John's wort isebenza kwizithunywa zamakhemikhali ebuchosheni ezingathinta imizwa yokwelapha ukucindezeleka okuncane, okufana nendlelai-serotonin reuptake inhibitors ekhethiwe (SSRIs) umsebenzi. I-Hypericin bekuvame ukucatshangwa njengesithako esisebenzayo maqondana nokwelapha ukudangala, kuchaza uDkt Weed. Njengamanje kucatshangwa ukuthi i-hyperforin iyisithako esisebenzayo ngemiphumela kuma-neurotransmitters ebuchosheni afana nemiphumela yama-anti-depressants kadokotela.

Izimpawu zokuya esikhathini

Uma kuziwa ekwelapheni izimpawu zokuya esikhathini, ukwengezwa kwamakhambi kukhonjisiwe ukuthi kuyasebenza ekwelapheni izimpawu ezingokwengqondo ezihlobene nokunqamuka kokuya esikhathini, njengokudabuka, ukukhathazeka, kanye nengcindezi, kanye ne izimpawu zomzimba njengokukhanya okushisayo nokujuluka ebusuku. Ngenkathi okutholakele kubaluleke kakhulu ngokwezibalo lapho i-wort yaseSt.John ithathwa yodwa, lapho ithathwa eceleni kwe-black cohosh, imifino yezimbali, ucwaningo luphoqelela kakhulu.

Ikhono leSt.John lokwelapha izimpawu zokunqamuka kokuya esikhathini licatshangelwa ukuthi lisebenze ngokufana nekhono lalo lokwelapha ukudangala okuncane kanye nokuphazamiseka kwesizini, kuyilapho imiphumela yalo ezimpawu zomzimba ezinjengokushisa okushisayo ingacwaningisiswa kabanzi futhi iyaqondakala. Ngenxa yendlela iSt. John's wort ewathinta ngayo amazinga obuchopho be-serotonin, kungenzeka futhi ukuthi isebenze ekwelapheni i-premenstrual syndrome.



Izifo ezivuthayo

Ngenkathi lolu hlelo lweSt.John's wort lungafundwa kabanzi njengabanye, isengezo sikhonjisiwe ukuthi sisebenza njenge-anti-inflammatory agent amagundane namagundane ngokunciphisa ukubonakaliswa kwama-inflammatory agents emzimbeni.

Ikhonsathi lezinto ezikhishwe eSt. John's wort lisebenza ndawonye ukunciphisa umsebenzi noma ukunciphisa ukukhiqizwa kwama-ejenti athile wokuvuvukala.

Ukusika okuncane nokusha

NgokukaDkt. Nance, isithasiselo semifino kwesinye isikhathi sisetshenziswa njengokwelashwa kwama-antibacterial ukusikeka okuncane nokusha. Ngenkathi kunemikhiqizo eminingi ye-topical yaseSt. ucwaningo lukhombisa ukuthi ukwakheka ngomlomo kunomthelela omuhle ekwelapheni isilonda kunezindlela zokwelapha ngezihloko eziqukethe i-wort yaseSt.



I-wort yaseSt.John kukholakala ukuthi iyaphumelela ekwelapheni amanxeba amancane ngenxa ye-hyperforin, ingxenye eyinhloko yama-antibacterial ekwengezeni kwamakhambi. I-Hyperforin isebenza ukubambezela ukukhula kwezinhlobo ezithile zamagciwane akhona ngaphakathi kokusikeka kanye namanxeba. Izifundo ezengeziwe zikhomba ukuthi i-hypericin ese-St. John's wort ingasebenza ekunciphiseni izinhlobo ezithile zamagciwane.

Imithamo

Umthamo ovamile we-wort St. John’s wort usukela ku-300 mg kuye ku-900 mg ngosuku othathwe ngemithamo ehlukanisiwe. Kubalulekile ukubonisana nodokotela wakho ngomthamo ofanele kuwe; uzobheka eminye imithi oyiphuzayo nomlando wakho wezokwelapha. I-St. John's wort ihlukaniswa njengesengezo sokudla, okusho ukuthi, njengeminye imithi yemvelo, ayiqashwa yi-FDA. Kubalulekile ukwenza ucwaningo oluthile ukuthola umkhiqizo wekhwalithi ukwelapha isimo sakho. Zama uku gwema ukuthenga isengezo esivela kwelinye izwe lapho uthenga ku-inthanethi.



Lapho uthatha i-wort yaseSt. John ukwelapha izimpawu ezimnene zokucindezeleka, vumela amasonto ambalwa ukuthi i-hyperforin engaphakathi kwesengezo ibe nomthelela kuma-neurotransmitters, afana nemithi kadokotela yokulwa nokucindezelwa. Imvamisa kuthatha amasonto ambalwa ukuthi imishanguzo yokuguqula i-neurotransmitter ibe nomthelela esimweni sengqondo, kusho u-Weed. Futhi, njenganoma iyiphi i-anti-depressant, lapho uyeka ukuthatha iSt John's wort, kufanele uyithathe kancane, kunokuba uyimise ngokungazelelwe. Umhlinzeki wakho wezokunakekelwa kwempilo angakweluleka ngohlelo olufanele lokuthwebula.

Imiphumela yesikhathi eside ye-St. John's wort ayifundwa kangako. Ngenxa yalokhu, ochwepheshe abaningi bezempilo bazoncoma ukunciphisa ukusetshenziswa kwayo kungapheli ezinyangeni eziyisithupha. Ngoba kunamakhemikhali amaningi ahlukahlukene eSt.John's wort, ngayinye inengxenye yempilo yayo, futhi ngenxa yokuthi umzimba womuntu ngamunye wehlukile, umuntu kufanele acabange ukuthi imiphumela yokuhlala kukaSt.John's wort ohlelweni lomuntu 'amasonto ambalwa, uDkt Weed uyanezela.



Imiphumela emibi ye-wort yaseSt

Imiphumela emibi kakhulu yokuthatha i-wort yaseSt.

  • Ukuqunjelwa kwesisu
  • I-Anorgasmia (kunzima ukufinyelela ku-orgasm)
  • Ukuqunjelwa
  • Isizungu / ukudideka
  • Umlomo owomile
  • Ubuhlungu bekhanda
  • Umfutho wegazi ophezulu (ukwanda kwengcindezi yegazi)
  • Isicanucanu
  • I-photosensitivity (ububomvu besikhumba / ukuqubuka / ukusha nokuchayeka elangeni)
  • Ukukhathala / ukuthambisa
  • Imvamisa ye-Urinary (inyukile)
  • Amaphupho acacile

Ngaphezu kwalokhu kusabela okuphikisayo, iSt John's wort ingadala ukusabela okusongela impilo, okubizwa nge-serotonin syndrome, lapho ithathwa ngemithi ethile. Iserotonin syndrome ingenzeka ngenxa yokwakhiwa kwe-serotonin eningi kakhulu. Izimpawu zayo zifaka phakathi: ukuxokozela, i-hyperthermia (ukushisa ngokweqile), ukujuluka, i-tachycardia (ukushaya kwenhliziyo okusheshayo), nokuphazamiseka kwe-neuromuscular, kufaka phakathi ukuqina. Kufanele ufune usizo lwezokwelapha ngokushesha uma uhlangabezana nalezi zimpawu.



Ukusebenzisana

Ngenxa yokuthi i-wort yaseSt. John inokuxhumana okuningi nemithi engaphezulu kwamanani kanye nemithi kadokotela, kubalulekile ukuthi uhlole nomhlinzeki wakho wezokunakekelwa kwempilo ukuze ubone ukuthi kuphephile yini kuwe. I-St. John's Wort yaziwa ngokuxhumana nemithi eminingi ngenxa yomphumela wayo ekuwohlokeni kweminye imishanguzo, kusho uDkt. Nance.

Kubalulekile ukuba nengxoxo nodokotela wakho noma usokhemisi ngaphambi kokuqala uhlobo lwemithi ye-wort yaseSt ukuxhumana kwezidakamizwa . Abanye ochwepheshe bezokwelapha bakholelwa ukuthi izingozi zidlula izinzuzo ezingaba khona, kufaka phakathi uDkt Weed. Ukwehluleka kokwelashwa okubangelwe yiSt.John's wort kuye kwabikwa nge-anticoagulation, i-HIV, ukutheleleka kwefungal, i-glaucoma, izitho ezifakwe kabusha, i-arrhythmias yenhliziyo, kanye nokuvimbela inzalo, usho kanjalo. Lapho uthatha ngokwengeziwe, imiphumela iba mibi ngokwengeziwe.

Izidakamizwa ezilandelayo zingase zingasebenzi kahle uma zithathwa nge-wort yaseSt.

  • I-Alprazolam (Xanax)
  • Ama-anticonvulsants: Ukwehla kokusebenza kungaholela ekulahlekelweni kokulawulwa kokubanjwa.
  • Izikhunta
  • Izidambisigciwane
  • Ama-barbiturates
  • I-Bupropion (Wellbutrin)
  • I-Digoxin
  • Ukulawulwa kokubeletha kwehormonal (amaphilisi okulawula ukubeletha, amabala, namasongo): Ukwehla kokusebenza kokulawulwa kokubeletha kungaholela ekuphumeni kwegazi ngokungajwayelekile noma ekukhulelweni okungahleliwe.
  • Ama-immunosuppressives ( ICyclosporine )
  • I-Irinotecan
  • Izidakamizwa: Inhlanganisela ingandisa ingozi yesifo se-serotonin.
  • I-Omeprazole (Prilosec)
  • I-Simvastatin (Zocor)
  • I-Warfarin (Coumadin)

Izidakamizwa ezilandelayo zingadala i-serotonin syndrome esongela impilo lapho ithathwa nge-wort yaseSt.

  • I-Fluoxetine (Prozac)
  • I-Sertraline (Zoloft)
  • Yonke i-serotonin reuptake inhibitor ekhethiwe (SSRIs) kanye ne-serotonin-norepinephrine reuptake inhibitors (SNRIs)
  • Ama-Triptans (isigaba semithi esetshenziselwa i-migraine, njenge-Imitrex, noma i-sumatriptan)

Lapho kuthathwa i-wort yaseSt i-fexofenadine (Allegra) , it kungadala ukwakheka futhi uqinise imiphumela emibi ejwayelekile.

Uhlu olungenhla alulona uhlu olubanzi lokusebenzisana kwezidakamizwa, kepha luhlinzeka ngezibonelo ezithile. Qiniseka ukuthi uthintana nomhlinzeki wakho wezokunakekelwa kwempilo ukuze uqinisekise ukuthi iSt. John's wort ilungile futhi iphephile ukuyithatha nganoma yimiphi eminye imithi (incwadi kadokotela kanye ne-over-the-counter, kufaka phakathi ezinye izithasiselo) ozisebenzisayo njengamanje.

Ukucatshangelwa okungu-3 ngaphambi kokuthatha iSt John's wort

I-St. John's wort isetshenziswe amakhulu eminyaka njengomuthi ohlukile ngamasiko ehlukahlukene ukwelapha izifo ezisukela ekukhathazekeni nasezimpawu zokucindezeleka ukulimaza nokushisa ukunakekelwa. Ukunquma ukuthi umuthi wamakhambi ukufanele yini kudinga ukubhekelwa okumbalwa.

liyini izinga elijwayelekile likashukela egazini kowesifazane
  1. Isimo ofuna ukuselapha: I-St. John’s ithembisa kakhulu ukwelapha ukudangala okuncane, izimpawu zokunqamuka kokuya esikhathini, nokusikeka okuncane nokusha. Ukwelapha ukucindezeleka okukhulu noma amanxeba abucayi kudinga indlela ehlukile kuneSt. Ngokwengeziwe, akuvamisile ukuthi kunconywe ukwelashwa kokucindezeleka ngaphandle kokubandakanyeka kukadokotela, ngakho-ke funa umbono wezokwelapha owuhloniphayo ngaphambi kokuqala uhlobo lwakho lwe-wort St. John's wort ngalezi zinhloso.
  2. Ucabanga ukuthi uzothatha isikhathi esingakanani ukuthatha isengezo: Ngoba imiphumela yesikhathi eside yokuthatha i-wort yaseSt. John ayifundwa kabanzi, kunconywa ukwelapha izimo ezingaxazululwa zingakapheli izinyanga eziyisithupha
  3. Imiphumela emibi nokusebenzisana: Cabanga ngemiphumela emibi nokuhlangana kwezidakamizwa zeSt. John's wort ngaphambi kokuthatha isengezo semithi.

Akunandaba ukuthi uzoyisebenzisa kanjani, ungalokothi uqale ukwelashwa nge-St John's wort ngaphandle kokubonisana nomhlinzeki wezokunakekelwa kwempilo, njengoba ukuhlangana okuningi okungathi sína kungenzeka.