Izidakamizwa ezibiza kakhulu zango-2019

Inkampani

AbaseMelika basebenzisa imali eningi emithini kadokotela kunanoma yimuphi omunye umuntu emhlabeni. Isakhamuzi esivamile sase-U.S $ 1,025 ngonyaka emithini yokwelashwa — lokho kukhuphuka kwamanani entengo okulungiswe ngokwehla kwamandla emali ama-11 kusukela ngo-1960, ngokusho kuka idatha kusuka ePeterson Centre on Healthcare kanye neKaiser Family Foundation.

Kungenxa yokuthi imishanguzo iyabiza.

Imithi eyishumi ekhangiswa kakhulu inezintengo zohlu ezisukela ku- $ 488 kuya ku- $ 16,938 ngenyanga noma inqubo yokwelashwa, kusho UMnyango Wezempilo kanye Nezinsizakalo Zabantu . Futhi, ucwaningo lwethu lukhombisa ukuthi imishanguzo eminingi ebekwa kaningi ibiza okungaphezulu kakhulu kwalokho.

Ngamanye amagama, kunezindlela eziningi ze- kakhulu izidakamizwa ezibizayo laphaya. Le yimithi ebiza kakhulu, ngokusho kwedatha ye-SingleCare. Izintengo ezibalwe ngezansi zibonisa intengo yemali — lokho okulindeleke ukuthi ikhasimende likhokhe uma lingenawo umshwalense noma ukumbozwa kadokotela.

Izidakamizwa	Izindleko ezimaphakathi zokunikezwa kwenyanga engu-1
Isibambiso	$ 33,001.08
Humira	$ 7,037.81
Umhlanganisi	$ 4,944.95
Xeljanz	$ 4,694.13
I-Forteo	$ 3,639.85
I-Glatiramer Acetate	$ 3,378.50
I-Norditropin	$ 3,377.89
Stribild	$ 3,356.06
I-Atripla	$ 3,215.15
I-Biktarvy	$ 3,214.05

1. Afinitor

Intengo yokuhlinzekwa kwezinsuku ezingama-28: $ 33,001.08

I-Afinitor, umuthi wokwelapha ngamakhemikhali osetshenziselwa ukwelapha izinso, i-pancreatic, isifuba nomdlavuza wobuchopho, ungomunye wemithi ebiza kakhulu laphaya — kodwa labo abanencwadi kadokotela bayayidinga yohlelo lwabo lokwelashwa. Imvamisa, isikhathi sokwelashwa nge-Afinitor sichazwa ngokuxilongwa kwezokwelapha. Iziguli ezitholwe zine-Subependymal Giant Cell Astrocytoma zithole i- ukwelashwa okuphakathi wezinyanga ezingama-24.4. Isikhathi esiphakathi sokwelashwa kweziguli ezitholwe zine-Renal Cell Carcinoma yizinsuku eziyi-141. Lokho kubiza okungenani (gulp): $ 166, 184.01 kumjikelezo wokwelashwa ojwayelekile.

Njengamanje, ayikho enye indlela ejwayelekile yomuthi wokusiza ukwehlisa izindleko. Umkhiqizi ongaba generic ulahlekelwe yicala lobunikazi ezinkantolo ekuqaleni kuka-2019, obekungavumela ukwakhiwa kwenguqulo ejwayelekile. Iziguli ezikhokha imali zibhekwa kumanani entengo ka- $ 33,000-plus. Kodwa kunezindlela zokonga kumaphilisi we-Afinitor 5 mg. Ngokuvumelana ne Imithi ,Amaphesenti ayi-100 wezinhlelo zeMedicare Part D kanye neMedicare Advantage zimboza lo muthi.

2. UHumira

Intengo yokuhlinzekwa kwezinsuku ezingama-28: $ 7,037.81

I-Humira i-immunosuppressant esetshenziselwa ukwelapha i-arthritis, i-psoriasis, isifo sikaCrohn, kanye ne-ulcerative colitis. Kube ngumuthi othengiswa kakhulu (owaziwa ngokuthi unenzuzo enkulu) esizweni kusukela ngo-2012, futhi awukhombisi zimpawu zokwehla. Ku-2018, imiyalo kaHumira ifike ngaphezu kwe- $ 14 billion, okwakungaphezulu kuka-60% ukwedlula unyaka owedlule-yize idumela eliyimpikiswano yemithi ye-biologic.

TO Ucwaningo lwe-2016 enyatheliswa yi Ijenali ye-American Medical Association lokho akubutholanga ubufakazi bokuhlangana phakathi kwezindleko zocwaningo nentuthuko nezintengo; kunalokho, imishanguzo kadokotela iyabizwa e-United States ngokuyinhloko ngesisekelo salokho okuzoqhutshwa yimakethe. Kodwa noma kunjalo, izindleko zeHumira ziyaqhubeka nokukhuphuka.Tintengo kaHumira inyuke isuka cishe ku- $ 19,000 ngonyaka (ngo-2012) yaya ngaphezu kwe- $ 38,000 ngonyaka (ngo-2019), ngesiguli ngasinye, ngemuva kwezaphulelo — ngokusho kwedatha ebikwe yi New York Times , evela kwa-SSR Health, inkampani yocwaningo. Lokho kukwanda ngamaphesenti ayi-100. Kepha for labo abathembele kulo muthi, kunezindaba ezinhle eza ngo-2023: umuthi we-biosimilar obizwa nge-Hyrimoz. Akufanele kudidaniswe nemithi ejwayelekile, ama-biosimilarskukhona kufana kakhulu imishanguzo esondele ngokwanele ekuphindaphindeni ukufeza imiphumela efanayo yokwelapha neyomtholampilo (kuyilapho ama-generic efana namakhemikhali afana nomuthi wokuqala). I-FDA ivume I-Hyrimoz futhi izotholakala ukuthengiswa eMelika ngoSepthemba 30, 2023.

3. Umhlanganisi

Intengo yokuhlinzekwa kwezinsuku ezingama-28: $ 4,944.95

I-Enbrel ngumuthi we-biopharmaceutical osetshenziselwa ukwelapha i-rheumatoid arthritis, i-psoriatic arthritis, nezinye izimo ezizimele. NjengoHumira, u-Enbrel ubona ukukhuphuka kokuthengisa kanye nemiyalelo egcwele, yize kunezindleko ezikhubaza isikhwama semali.I-Enbrel — eyafika emakethe yase-U.S ngo-1998 — yaqopha ama- $ 4.8 billion ekuthengisweni kwe-U.S ngo-2018, ngokusho komkhiqizi Amgen , Inc.

Njengamanje, umenzi wezidakamizwa ubiza inani lokunikezwa konyaka komthamo we-Enbrel wama-50-mg ngaphezulu kwama- $ 67,000.Futhi ayikho i-generic eseduze yokusiza ukunciphisa izindleko zeziguli.Ama-biosimilars amabili we-Enbrel avunyelwe yi-FDA futhi awakaqalwa okwamanje — kufaka phakathi eyodwa evela kubenzi bezidakamizwa baseSwitzerlandUNovartis AGukuthi i-ejensi yezempilo ivume ngo-2016,ngokuvumelana ne IWall Street Journal intatheli yezempilo UJared S. Hopkins . Amalungelo obunikazi angaphezu kwama-40 avikela i-Enbrel, futhi umenzi wayo, u-Amgen Inc., uwine isinqumo senkantolo ngo-Agasti esihlobene namalungelo obunikazi e-Enbrel.

4. Xeljanz

Intengo yokuhlinzekwa kwezinsuku ezingama-30: $ 4,694.13

I-Xeljanz iyi-biopharmaceutical ethandwayo enqunyelwe ukwelapha i-rheumatoid arthritis, i-psoriatic arthritis, ne-ulcerative colitis. Kepha muva nje, lesi sidakamizwa saba sematheni ngenxa ye-FDA entsha isexwayiso selebuli emnyama ukuthii-JAK inhibitor's 10-mg kabili umthamo wansuku zonke, owenzelwe ukunciphisa ubuhlungu obuhlangene nokuvuvukala,ukwandaengozini yamahlule egazi — futhi mhlawumbe nokufa.

Timvume yomuthi yokwelapha i-ulcerative colitis iye yaxoshwa — manje seyivunyelwe kuphela ezigulini ezingaphenduli noma ezingafanele eminye imithi.Kepha ngaphandle kwazo zonke izixwayiso ezibucayi ezungeze umthamo we-10-mg, i-5-mg isabhekwa njengephephile, futhi nayo ibone ukwanda kokuthengisa nokusetshenziswa.

5. I-Forteo

Intengo yokuhlinzekwa kwezinsuku ezingama-28: $ 3,639.85

I-Forteo ngumuthi ojojwayo osiza ukuqinisa amathambo kubantu abane-osteoporosis abasengozini enkulu yokuqhekeka-ikakhulukazi labo abane-osteoporosis ekuthatheni i-steroids efana ne-prednisone. Kuyindlela yokwenziwa yehomoni ngokwemvelo etholakala emzimbeni ekhuthaza ukukhula kwethambo elisha nokwanda kwamathambo. Imijovo ijwayele ukuthathwa ethangeni noma esiswini. Kuvunyelwe kuze kube izinyanga ezingama-24 zokusetshenziswa.

Okwamanje akukho okujwayelekile okutholakalayo. Kepha, uPfenix uzuze imvume yelungelo lobunikazi ngokufanayo umkhiqizo , okungadonsela phansi intengo lapho ifinyelela ekukhiqizeni. Sekunezindlela zokwelapha ezimbili ezifanayo eYurophu, kepha zivinjiwe e-United States. Uma udinga iForteo, kukhona ifayela le- isaphulelo somkhiqizi itholakalela iziguli ezifanelekile.

6. Inaliti ye-Glatiramer Acetate

Intengo yokuhlinzekwa kwezinsuku ezingama-30: $ 3,378.50

Umjovo we-Glatiramer acetate yinguqulo ejwayelekile ye- ICopaxone , umjovo wokujova osetshenziselwa ukwelapha i-multiple sclerosis futhi uvimbele ukubuyela emuva kwe-MS. Ngisho njengokujwayelekile, intengo iphezulu — hhayi ngaphansi kakhulu kunomlingani wegama lomkhiqizo.

Eminyakeni engama-20 edlule, kube nentuthuko enkulu ekwelashweni kwe-MS, kepha ukwanda kwezinketho zokwelashwa ezitholakalayo akuholelanga ekwehleni okufanayo kwamanani. Zilokhu zanda. Kusuka ku-2013 kuya ku-2018, izindleko ezijwayelekile eziphakathi kwezifo zokwelapha eziguqula i-glatiramer acetate zikhuphukile zisuka ku- $ 60,000 zaya ku- $ 80,000 ngokuya nge- I-National Multiple Sclerosis Society . Uma unenkinga yokusebenzisa imithi yakho, UMylan inikeza ukulondolozwa kwabantu abathile.

7.I-Norditropin Injection

Intengo yokuhlinzekwa kwezinsuku ezingama-30: $ 3,377.89

INorditropin iyi-hormone yokukhula yokwenziwa elingisa ama-hormone endlala ye-pituitary evuselela ukukhula emzimbeni: ukuphakama, izitho, amathambo, nemisipha. Uma isetshenziselwa izingane ezingenzi i-hormone yokukhula eyanele, kungazisiza zibe zinde. Kubantu abadala, kungakhuthaza ukukhula kwemisipha. Uma isetshenziselwa iziguli ngaphandle kokushoda, ayisebenzi.

Kuthathwa njengomuthi okhethekile, njengaleyo esetshenziselwa ukwelapha izimo ezinjengomdlavuza, i-HIV, noma isifo samathambo. Lezi zinhlobo zemithi ngokuvamile zibiza kakhulu, futhi i-norditropin ayiyona into ehlukile. UNovo Nordisk une- uhlelo losizo lweziguli endaweni yokusiza ekuzuzeni izinzuzo zomshuwalense futhi ukhokhele imithi.

8. Ukwakha

Intengo yokuhlinzekwa kwezinsuku ezingama-30: $ 3,356.06

I-Stribild iyi-cocktail yemithi emine kuthebhulethi eyodwa esetshenziselwa ukwelapha i-HIV futhi yehlise ubungozi bokudlulisela lesi simo kwabanye. Inemithi emithathu yezidambisigciwane kanye nomuthi osiza abanye ukuthi basebenze kangcono. Yize kubiza, kukhona ubufakazi obuthile ukuthi kanye ngosuku ukwelashwa okuhlanganisiwe kwe-HIV kushibhile isikhathi eside kunezinye izindlela ngoba kuthuthukisa ukubambelela emithini ezigulini, okunganciphisa ubungozi bezinkinga noma ukulaliswa ezibizayo. Umenzi we-Stribild, IGileyadi , inikeza izinhlelo zosizo lweziguli uma unenkinga yokunikeza ukwelashwa.

9. I-Atripla

Intengo yokuhlinzekwa kwezinsuku ezingama-30: $ 3,215.15

I-Atripla ngomunye umuthi ohlangene osetshenziselwa ukwelapha i-HIV, futhi wehlisa ingozi yokudlulisela lesi simo kwabanye. Inemithi emithathu. Okwamanje ayikho inguqulo ejwayelekile yalomuthi etholakalayo, egcina intengo iphakeme. Kepha, ukuqala ekupheleni kukaSepthemba 2020, Teva Pharmaceuticals ivunyelwe ukwethula izinhlobo ezijwayelekile, ezingasiza ekunciphiseni izindleko. Umkhiqizi we-Atripla, IGileyadi , inikeza izinhlelo zosizo lweziguli uma unenkinga yokunikeza ukwelashwa.

10. IBiktarvy

Intengo yokuhlinzekwa kwezinsuku ezingama-30: $ 3,214.05

IBiktarvy iyiphilisi lenhlanganisela yemithi emithathu esetshenziselwa ukwelapha i-HIV. Ayikho inguqulo ejwayelekile etholakalayo. Kusha idatha kukhombisa ukuthi kusebenza kahle ezigulini ezintsha, nasezigulini ezishintsha zisebenzisa eminye imithi, okuholele kuyo icishe iphindwe kabili ukuthengiswa kwalo muthi ngonyaka owodwa ngaphandle kwezindleko. Njengeminye imithi ehlangene ye-HIV, kunobunye ubufakazi bokuthi iyancipha izindleko zokwelashwa zesikhathi eside ngenxa yokuthuthuka kokubambelela. Umenzi weBiktarvy, IGileyadi , inikeza izinhlelo zosizo lweziguli uma unenkinga yokunikeza ukwelashwa.

Manje yini ebangela amanani aphezulu?

Kanjani (futhi kungani) izindleko zemithi eminingi edingekayo iphakama kangaka? Kuyinkimbinkimbi-futhi kuthintwa yizinto eziningi.

Imithi egama lomkhiqizo

Imakethe enegama lomkhiqizo kulapho kuqala ukwenziwa khona imithi, futhi ukwenza umuthi omusha kuyinqubo ebizayo futhi edla isikhathi. AbakwaBrands banokuvikelwa kwelungelo lobunikazi nokulawula eminyakeni yabo yokuqala yezimakethe, okuvumela abakhiqizi ukuthi basebenzise ngokugcwele izidingo zezindlela zabo zokwelashwa, futhi bavuze abatshalizimali ngokubekezela kwabo kanye nezindleko eziphezulu zocwaningo nentuthuko, kuchaza uDana Goldman, usihlalo womqondisi e-USC Schaeffer Center weNqubomgomo Yezempilo Nezomnotho kanye noProfesa Wenqubomgomo Yomphakathi, Ikhemisi, Nezomnotho. Ngamanye amagama, amanani entengo yokwelashwa okusha aphezulu ngoba kubiza kakhulu ukuwaletha ezimakethe.

Imithi ejwayelekile

Emakethe ejwayelekile, kuyindaba ehlukile. Lapho ilungelo lobunikazi lomuthi omusha liphela, abakhiqizi bangakha uhlobo olujwayelekile futhi baluthengise ngentengo ephansi kakhulu ngoba unjiniyela wokuqala uqoqe izindleko. Kodwa-ke, kwesinye isikhathi, ama-generics abiza kakhulu njengabalingani bawo abanophawu, njengentengo engazelelwe eyenyuka ngomuthi olwa nomalaleveva I-Daraprim , okwenze izindaba ngo-2015.

UMartin Shkreli noTuring Pharmaceuticals bathathe i- $ 13.50 ngephilisi ngalinye iDaraprim (ebelilokhu litholakala kusukela ngawo-1950s) bakhuphula intengo lafika ku- $ 750 ngephilisi. UShrkeli wayengakwenza lokhu ngoba intengo yeDaraprim yehle kakhulu kangangokuba bonke abahlinzeki babekhethe ukuphuma. UTuring wabe esengena futhi esebenzisa amandla akhe okubusa phezu kwesidakamizwa esasingenakho ukuvikelwa kwelungelo lobunikazi.

Lokhu kufakazela ukuthi, okuxakayo, ukuthi imithi ejwayelekile imakethe kwesinye isikhathi ingasebenza kahle kakhulu: Izidakamizwa zishibhile kakhulu masinyane futhi ukunikezwa okwanele kusengozini.

I-SingleCare ingasiza kanjani

Ngenxa yezindleko eziphezulu zemithi, abantu abaningi ngokwengeziwe bathembela ezinkampanini zokunakekelwa kwezempilo ezifana Okufanayo ukubasiza ukuthi bonge amakhulu (nezinkulungwane) zamaRandi kwimibhalo yabo. KwaSingleCare, sikholelwa ukuthi kubaluleke kakhulu ukuhlinzeka izaphulelo zemithi kadokotela kuwo wonke umuntu waseMelika akhululekile ukufinyelela, kungakhathalekile isimo somshuwalense, kusho uManav Malhotra, VP wemininingwane kwaSingleCare. Futhi njengoba silwela ukwenza ukuthi izidakamizwa zithengeke futhi zifinyeleleke kalula, ingxenye enkulu yalokho iqinisekisa ukuthi kunokucaca kwentengo kumthengi.

Futhi ngenkathi abaseMelika bejwayele ukuthenga ngamanani entengo, abakwenzi ngemithi. Kunzima ukucabanga ukuthenga noma yimuphi umkhiqizo ngaphandle kokwazi ukuthi kuzokubiza ini uze ufike kwirejista, kodwa lokho ngokwesiko ukuthi imboni yekhemisi yasebenza kanjani, kusho uMalhotra. Sifuna abathengi bazi kahle ukuthi bazokhokha kubaphi ozakwethu ekhemisi ngaphambi kokuba bangene ngaphakathi. Abathengi abaningi abaqapheli nokuthi amanani entengo ayahluka phakathi kwamakhemisi ngaphesheya nje komgwaqo komunye nomunye. Imakethe eqhutshwa ngumthengi onolwazi owenza izinqumo ezinolwazi yisinyathelo sokuqala sokwehlisa amanani.

I-SingleCare inikeza amashadi wokubonisa ngentengo akuvumela ukuba uqhathanise intengo yemali nokulondolozwa kwe-SingleCare kwezidakamizwa ngonyaka odlule.Ukunikela ngokulondolozwa okuhle kakhulu kusenhliziyweni yakho konke okwenziwa yi-SingleCare. Siphinde sibheke nezidakamizwa abathengi abazikhathalelayo ukunquma ukuthi singagxilisa kuphi imizamo yethu ekunciphiseni amanani entengo, kusho uMalhotra. Ishayela ukuthi sizenza kanjani izinqumo zethu zamanani nezingxoxo zethu nabalingani bethu bekhemisi.

Qala ukufuna imithi yakho lapha ukubona ukuthi ungonga kangakanani.