Ingabe kufanele uthathe i-Topamax yama-migraines akho?
Imininingwane YezidakamizwaNjengokungathi ukuba ne-migraines ejwayelekile akubuhlungu ngokwanele, ukuthola ukuthi imuphi umuthi-noma inhlanganisela yemithi ekufanele kungaba yinselelo enkulu. Ngokujabulisayo, kunezindlela eziningi zokwelapha ezikhona ekuvimbeleni nasekunciphiseni ubuhlungu. Lokho kuyizindaba ezinhle ze- BaseMelika abayizigidi ezingama-38 abahlala ne-migraine.
Enye yalezo zinketho, I-Topamax ( topiramate ), kunqunywe kabanzi njengemithi yokuvikela i-migraine, yize isetshenziswe okokuqala njengesidakamizwa se-antiepileptic sabantu abanomlando wokubanjwa.
Eqinisweni, i-topiramate empeleni iyimithi evinjelwe kakhulu yokuvimbela umlomo ye-migraines e-United States-njengoba ivunyelwe ukwelashwa kwe-migraine kubantu abadala ngo-2004, ngokusho UDeborah I. Friedman , MD, uprofesa wezinzwa e-University of Texas Southwestern Medical Center nelungu le-American Headache Society.
I-Topamax isebenza kanjani ngemigraines?
Empeleni, leyo ngxenye ye-puzzle ayisaziwa.
I-Topiramate isebenza ngezinqubo ezahlukahlukene, futhi akucaci ukuthi yikuphi okubalulekile ku-migraine, kusho uDkt Friedman, echaza ukuthi i-topiramate isebenza ngemigudu ye-sodium ne-calcium emzimbeni, kanye nakuma-receptor ahlukene lapho izinzwa zithumela khona amasiginali.
Ngokuqondene nokutholakala kwe-topiramate kungathuthukisa izimpawu ze-migraine, bekuyingozi kakhulu. UFriedman uthi iziguli ezinesifo sokuwa zibike ukwenyuka kwezimpawu zazo ze-migraine ngenkathi zithatha i-topiramate nezinye izidakamizwa ezifanayo.
Ngingakanani i-Topamax okufanele ngiyithathe i-migraines?
Umthamo we-Topamax we-migraines uvame ukuba mncane kunesifo sokuwa, odokotela abaningi beqala phansi futhi benyuse inani kancane kancane ngokuhamba kwesikhathi, ngokusho UDanny Park , MD, oyinhloko yesigaba se-neurology eSweden Covenant Hospital eChicago.
Umthamo ojwayelekile uqala ngamathebulethi angama-milligram angama-25 kabili ngosuku, usho kanjalo. Ukunciphisa imiphumela emibi, ngivame ukukhuphuka ngama-milligram angama-25 nsuku zonke ngesonto… [ngomthamo omkhulu wokuba cishe ngama-milligram ayi-100 kabili ngosuku.
Yimiphi imiphumela emibi ejwayelekile ye-Topamax ye-migraines?
Yize i-Topamax ingaphumelela ekwehliseni imvamisa nobukhulu be-migraines, leyo mpumelelo ivame ukuza ngentengo-abantu abaningi balwa kanzima ukubekezelela imiphumela emibi ejwayelekile yomuthi, uDkt Friedman athi angafaka:
- ukuzwa, izikhonkwane nezinaliti ukuzwa emaphethelweni noma ebusweni
- ukulahlekelwa isifiso sokudla okuholela ekunciphiseni isisindo
- ukulala / ukozela
- isicanucanu
- Inkungu yobuchopho
UDkt.Park uyanezela ukuthi le miphumela emibi ingatholwa ebangeni ngalinye lemithamo ye-topiramate ngokuya ngesiguli ngasinye.
Ngineziguli ezithile ezifika kumamiligram ayikhulu kabili ngosuku [ngaphandle kwemiphumela emibi] futhi ngeshwa ezinye iziguli ezingabekezeleli ngisho namamiligremu angama-25 nsuku zonke, usho kanjalo.
Ngabe iTopamax ingakusebenzela?
Akudingeki ukuthi ube nesifo esingelapheki se-migraine (okungukuthi, umuntu onezinsuku eziyi-15 noma ngaphezulu zemigraine ngenyanga, ngokusho I-American Migraine Foundation ) ukuzuza emithini yokuvikela efana neTopamax. Kodwa uDkt. Friedman uthi iziguli eziphendula umuthi ngokuvamile zinezinye izinto ezimbalwa ezifanayo.
Sicabanga ngemithi yokwelashwa ye-migraine kubantu abanezinsuku okungenani ezine zekhanda ngenyanga abanokukhubazeka okunzima okuvela emigraines, usho, okusho ukuthi imigraines yakho ikuvimbela ekwenzeni imisebenzi yakho ejwayelekile yansuku zonke.
Futhi kufakwe abantu abanokukhululeka okunganele emithini yokwelashwa ye-migraine nalabo abanezinhlobo ezikhethekile ze-migraine (njenge i-hemiplegic noma i-brainstem aura ) kungakhathalekile ukuthi kuvame kangakanani.
Noma kunjalo, i-topiramate ayifanele wonke umuntu. UFriedman uthi ayikwazi ukuthathwa ngesikhathi sokukhulelwa, futhi uzocabanga kabili ngokuyinikeza umuntu onomlando wamatshe ezinso asuselwa ku-calcium ngoba amanye ucwaningo kubonisa ukuthi i-topiramate ingakhuphula ubungozi bokuyithuthukisa.
Izinzuzo zokuthatha i-Topamax
Kungathatha isikhashana ukuthi uzizwe ngokugcwele nge-Topamax ye-migraines-uDkt. UFriedman uthi abantu abaningi babona intuthuko ngenyanga yokuqala, kepha ingaqhubeka ithuthuke ngonyaka wokuqala. Uphinde wathi izivivinyo zokwelashwa ezedlule zikhombisile abantu abangama-50% abazizwa bengcono ngama-50% ku-topiramate, abanye bebika izinga lokuphendula eliphakeme kakhulu.
Kodwa imiphumela emibi yi-topiramate enkulu kakhulu; abanye abantu bamane abakwazi ukubabekezelela.
Kungumuthi ‘wokuthanda noma ukuzonda’, kusho uDkt. Friedman, futhi kwesinye isikhathi abantu bayesaba ukuwuthatha ngoba bezwa ngemiphumela engemihle. Kepha akuwona wonke umuntu obatholayo, ngakho-ke kubalulekile ukuthi ube nomqondo ovulekile ngakho.
