Main >> Izidakamizwa Vs. Umngani >> I-Ampicillin vs. i-amoxicillin: Umehluko, ukufana, nokuthi yikuphi okungcono kuwe

I-Ampicillin vs. i-amoxicillin: Umehluko, ukufana, nokuthi yikuphi okungcono kuwe

Izidakamizwa Vs. Umngani

Uma ngabe uke waba nokutheleleka ngamagciwane, kungenzeka ukuthi uthathe i-antibiotic. I-Ampicillin ne-amoxicillin yilezi ama-antibiotic esetshenziselwa ukwelashwa kwezifo ezahlukahlukene zamagciwane. Yomibili le mithi ivunywa yi-U.S. Food and Drug Administration (FDA). Imithi elwa namagciwane unomsebenzi wokulwa namagciwane futhi usetshenziselwa ukwelashwa kwezifo ezibangelwa amagciwane kuphela-awusebenzi ekwelapheni izifo ezibangelwa amagciwane (njengomkhuhlane noma umkhuhlane ovamile).

I-Ampicillin ne-amoxicillin zihlukaniswa eqenjini lemithi ebizwa nge-penicillin (noma i-aminopenicillin), noma i-beta-lactam antibiotics. Zisebenza ngokuvimbela amabhaktheriya ekwakheni izindonga zamangqamuzana, okuholela ekufeni kwamagciwane. Womabili la ma-antibiotic asetshenziselwa ukwelapha izifo ezahlukahlukene zamagciwane (ngaphezulu kulokhu ngezansi).

Yize i-ampicillin ne-amoxicillin kukhona kokubili i-penicillin ama-antibiotic, awafani ncamashi. Qhubeka ufunde ukuze ufunde kabanzi nge-ampicillin ne-amoxicillin.

Uyini umehluko omkhulu phakathi kwe-ampicillin ne-amoxicillin?

I-Ampicillin iyi-antibiotic ye-penicillin. Isetshenziselwa ukwelapha amagciwane amaningi ane-gram-positive ne-gram-negative. Igama lomkhiqizo le-ampicillin yi-Principen; kodwa, i-Principen ayisatholakali njengomuthi wegama lomkhiqizo. Imithi iyatholakala njenge-generic, ampicillin, njenge-capsule yomlomo noma njengomjovo. I-Ampicillin nayo iyatholakala ngefomu lomjovo njenge-Unasyn, equkethe i-ampicillin kanye ne-sulbactam (ukuvimbela ukumelana namagciwane). I-Unasyn ayisatholakali njengomkhiqizo — itholakala njenge-generic ampicillin / sulbactam kuphela.

I-Amoxicillin nayo iyi-antibiotic ye-penicillin. Ifana ngokwamakhemikhali ne-ampicillin futhi inomsebenzi obanzi omelene namagciwane amaningi ane-gram-positive ne-gram-negative.

Igama lomkhiqizo le-amoxicillin yi-Amoxil; kodwa, i-Amoxil ayisatholakali ngokuhweba. Umuthi utholakala kuphela ngendlela ejwayelekile ye-amoxicillin. I-Amoxicillin ivame ukubekwa njengamaphilisi we-amoxicillin kubantu abadala, noma ukumiswa kwezingane, noma ngokuhlanganiswa ne-clavulanic acid (evimbela ukumelana nama-antibiotic) njengomuthi obizwa nge-Augmentin.

Kubalulekile ukukhumbula ukuthi uma uthatha i-antibiotic, kufanele uyiphuze njengokuyalelwa, futhi qeda inkambo ephelele , noma ngabe uzizwa ungcono ngaphambi kokuba ukwelashwa kuphele. Kodwa-ke, uma ngabe uphuza i-antibiotic yakho izinsuku ezimbalwa futhi awuzizwa ungcono noma uzizwa ubi kakhulu, xhumana nomhlinzeki wakho wezokunakekelwa kwezempilo ukuze akuthole.

Umehluko omkhulu phakathi kwe-ampicillin ne-amoxicillin
	I-Ampicillin	I-Amoxicillin
Isigaba sezidakamizwa	I-penicillin (beta-lactam) antibiotic	I-penicillin (beta-lactam) antibiotic
Isimo somkhiqizo / ejwayelekile	Okujwayelekile	Okujwayelekile
Ngubani igama lomkhiqizo?	I-Principen (ayisatholakali ngegama lomkhiqizo)	I-Amoxil, Trimox (ayisatholakali ngegama lomkhiqizo)
Izidakamizwa zingena ngaziphi izinhlobo?	I-Ampicillin: i-capsule, umjovo Unasyn: (ampicillin-sulbactam): umjovo	I-Amoxicillin: i-capsule, ukumiswa, ithebhulethi, ithebhulethi ehlafunwayo I-Augmentin : (amoxicillin-clavulanate): ithebhulethi, ithebhulethi ehlafunwayo, ukumiswa I-Prevpac: inkambo yokwelashwa equkethe amaphilisi we-amoxicillin ahlanganiswe ne-lansoprazole ne-clarithromycin (esetshenziselwa izilonda zesisu ezibangelwa yi-H. pylori bacteria)
Uyini umthamo ojwayelekile?	Isibonelo: ampicillin 500 mg njalo emahoreni ayisithupha izinsuku eziyi-10-14	Isibonelo: i-amoxicillin 500 mg kathathu ngosuku izinsuku eziyishumi
Yelashwa isikhathi esingakanani?	Izinsuku eziyi-10-14; zingahluka	Izinsuku 7-10; zingahluka
Ubani ovame ukusebenzisa umuthi?	Abantu abadala nezingane	Abantu abadala nezingane

Izimo eziphathwa yi-ampicillin ne-amoxicillin

I-Ampicillin isetshenziselwa ukwelapha ukutheleleka ngamagciwane kufaka phakathi:

Ukutheleleka kwe-genitourinary tract, kufaka phakathi i-gonorrhea, okubangelwa coli, P. mirabilis , enterococci, Shigella, S. typhosa kanye namanye ama-Salmonella nokukhiqiza i-penicillinase N. gonorrhoeae
Izifo zokuphefumula ezibangelwa ukungakhiqizi kwe-penicillinase umkhuhlane kanye ne-staphylococci, ne-streptococci kufaka phakathi I-Streptococcus pneumoniae
Ukutheleleka kwamathumbu emathunjini okubangelwa Shigella, S. typhosa nokunye Salmonella, E. coli, P. mirabilis , kanye ne-enterococci
I-meningitis ibangelwa I-Meningitidis

I-Amoxicillin isetshenziselwa ukwelapha izifo ezahlukahlukene zamagciwane:

Ukutheleleka endlebeni (i-otitis media), ukutheleleka emakhaleni, noma ukutheleleka komphimbo okubangelwa izinhlobo ezithile ze I-Streptococcus , pneumoniae , I-Staphylococcus spp., noma Haemophilus influenzae
Izifo zomgudu womchamo obangelwa U-Escherichia coli, P. mirabilis, noma I-Enterococcus faecalis
Ukutheleleka kwesikhumba noma ukutheleleka kwesakhiwo sesikhumba okubangelwa izinhlobo ezithile ze IStreptococcus, iStaphylococcus (njengeStaphylococcus aureus), noma E. coli
Izifo zomgudu wokuphefumula ezingezansi ezibangelwa yizinhlobo ezithile ze- I-Streptococcus , IStreptococcus pneumoniae, iStaphylococcus , noma H. influenzae
I-gonorrhea eyindida eyinkimbinkimbi emadodeni nakwabesifazane ebangelwa I-Neisseria gonorrhoeae
Ukuqedwa kwe pylori ukunciphisa ubungozi bokuphindaphinda kwesilonda se-duodenal
I-Amoxicillin isetshenziswa futhi njengokwelapha kathathu nge-lansoprazole ne-clarithromycin (njenge-Prevpac) ezigulini ezine pylori ukutheleleka kanye nesilonda se-duodenal

Imithi elwa namagciwane efana ne-ampicillin noma i-amoxicillin kufanele isetshenziswe kuphela kwizifo ezibangelwa amagciwane lapho kunqunywa ukuthi kufanelekile ngumhlinzeki wakho wezokunakekelwa kwempilo. Lokhu kusiza ukuvimbela ukumelana namagciwane. Izikhungo Zokulawula Nokuvimbela Izifo ( i-CDC ) ikhuthaza ukusetshenziswa okufanele kwama-antibiotic ngokusiza abahlinzeki bezempilo ukuthi bakhethe i-antibiotic efanele futhi banciphise ukusetshenziswa kwama-antibiotic okungadingekile lapho belapha izifo ezahlukahlukene ezithathelwanayo. Lokhu kubizwa ngokuthi ukuphathwa kwama-antibiotic.

Ingabe i-ampicillin noma i-amoxicillin isebenza kangcono?

Izifundo eziqhathanisa lezi zidakamizwa ezimbili azisona zakamuva futhi / noma zisebenzise usayizi wesampula omncane kakhulu. Ucwaningo olulodwa , kusukela ngo-1974, waqhathanisa le mithi emibili yokutheleleka ezindlebeni ezinganeni futhi wathola ukuthi yomibili le mithi isebenza ngokufanayo. I-Amoxicillin ibekezeleleke kangcono, inemiphumela emibi embalwa kune-ampicillin.

I-Ampicillin iyodwa ayibekiwe njengoba yayinjalo esikhathini esedlule , ngenxa yokuthuthuka kokumelana nemithi. Njengamanje, i-amoxicillin ibekiwe kabanzi. Kodwa-ke, i-ampicillin ihlangene ne-sulbactam (Unasyn) ivame ukunikezwa njengomjovo esimweni sesibhedlela. I-Sulbactam yisidakamizwa esibizwa nge-beta-lactamase inhibitor futhi sisiza ukuvimbela ukumelana nemithi. Esimeni sokugula, lokhu kufana nesiguli esithatha i-Augmentin, eyi-amoxicillin kanye ne-clavulanic acid, i-beta-lactamase inhibitor.

Umuthi osebenza kahle kakhulu unganqunywa ngumhlinzeki wakho wezokunakekelwa kwempilo, ongathola isifo sakho njengegciwane noma igciwane. Uma ukutheleleka kuyigciwane, isinqumo sokuthi iliphi i-antibiotic oyisebenzisayo izosuselwa kulokho amagciwane abangela ukutheleleka (uma kwaziwa, noma uma kungaziwa, imaphi amabhaktheriya okusolwa ukuthi abangela ukutheleleka). Ummeli wakho uzobheka umlando wakho ogcwele wezokwelapha kanye nezinye izimo zezokwelapha onazo neminye imithi oyiphuzayo engasebenzisana ne-ampicillin noma i-amoxicillin.

Thola ikhadi lesaphulelo sekhemisi

Ukuhlanganisa kanye nezindleko ze-ampicillin vs. i-amoxicillin

I-Ampicillin ne-amoxicillin zimbozwe yizinhlelo eziningi zomshuwalense kanye neMedicare Part D.

Umuthi ojwayelekile we-ampicillin ungaba ngama-capsules angama-40, 500 mg. Intengo ephaketheni ingaba cishe ngama- $ 30. Ukusebenzisa ikhadi le-SingleCare le-ampicillin kungehlisa intengo ibe ngaphansi kwama- $ 20.

Umuthi ojwayelekile we-amoxicillin ungaba ngama-capsules angama-30, 500 mg. Intengo ephume ephaketheni ingaba ngaphezu kwama- $ 20. Ngekhuphoni lesaphulelo se-amoxicillin i-SingleCare ungakhokha imali engange- $ 5 nje kuphela.

	I-Ampicillin	I-Amoxicillin
Ngokuvamile embozwe umshwalense?	Yebo	Yebo
Imbozwe ngokwejwayelekile yi-Medicare Part D?	Yebo	Yebo
Umthamo ojwayelekile	40, 500 mg amaphilisi	30, 500 mg amaphilisi
Inkokhelo ejwayelekile yeMedicare Part D	$ 0- $ 1	$ 0- $ 1
Izindleko ze-SingleCare	$ 20 +	$ 5 +

Imiphumela emibi ejwayelekile ye-ampicillin vs. amoxicillin

Imiphumela emibi kakhulu ye-ampicillin ne-amoxicillin ihlobene nokuzwela kwe-penicillin futhi kungenzeka kakhulu ukuthi yenzeke ezigulini ezake zaba ne-hypersensitivity kuma-penicillin nasezigulini ezinomlando wokungezwani komzimba kanye / noma i-asthma. Imiphumela emibi ejwayelekile ifaka isicanucanu, ukuhlanza, isifo sohudo, kanye nokuqubuka kwesikhumba / ukusabela kwe-hypersensitivity. Ukusabela okubucayi kwe-anaphylactic kudinga ukwelashwa okuphuthumayo.

Ngokuvamile, ukwelashwa ngemithi elwa namagciwane kungakwenza uthambekele kakhulu kuhudo noma ekungenweni imvubelo. Buza umhlinzeki wakho wezokunakekelwa kwempilo uma kufanele uthathe ama-probiotic .

Lolu akulona uhlu olugcwele lwemiphumela emibi-eminye imiphumela emibi ingavela. Xhumana nomhlinzeki wakho wezokunakekelwa kwempilo ukuthola uhlu olugcwele lwezehlakalo ezimbi.

	I-Ampicillin	I-Amoxicillin
Umphumela oseceleni	Kusebenza?	Imvamisa	Kusebenza?	Imvamisa
Uhudo	Yebo	Akubikiwe	Yebo	> 1%
Isicanucanu	Yebo	Akubikiwe	Yebo	> 1%
Ubuhlungu besisu	Yebo	Akubikiwe	Yebo	Akubikiwe
Ukuhlanza	Yebo	Akubikiwe	Yebo	> 1%
I-Rash	Yebo	Akubikiwe	Yebo	> 1%

Umthombo: DailyMed ( ampicillin ), IDailyMed ( amokfillin ), Ilebula le-FDA ( amokfillin )

Ukusebenzisana kwezidakamizwa kwe-ampicillin kuqhathaniswa ne-amoxicillin

I-Ampicillin ne-amoxicillin zinohlu olufanayo lokusebenzisana kwezidakamizwa ngoba ziyimithi efanayo yokwakheka.

Ukuthatha i-ampicillin noma i-amoxicillin ene-anticoagulant efana ne-warfarin kungathinta ukopha — iziguli kufanele ziqashwe uma zikule nhlanganisela. Futhi, i-allopurinol, umuthi we-gout, ngokuhlangana ne-ampicillin noma i-amoxicillin ingakhuphula amathuba okuba nokuqubuka.

Izindlela zokuvimbela inzalo ngomlomo (ezaziwa nangokuthi amaphilisi okulawula ukubeletha) zingasebenza kancane uma zithathwa zihlangene nama-antibiotic anjenge-ampicillin noma i-amoxicillin. Xhumana nomhlinzeki wakho wezokunakekelwa kwempilo ngesidingo sokulawulwa kokuzalwa kokusekelwa (njengekhondomu) ngenkathi uthatha i-antibiotic.

I-Ampicillin ne-amoxicillin zombili ziyasebenzisana nomuthi wokugomela ophilayo womlomo we-typhoid, uVivotif Berna. Imithi elwa namagciwane ingavimbela umuthi wokugoma.

Lolu akulona uhlu oluphelele lokuhlangana kwezidakamizwa — okunye ukuhlangana kwezidakamizwa kungenzeka. Xhumana nomhlinzeki wakho wezokunakekelwa kwempilo ukuthola uhlu oluphelele lokuhlangana kwezidakamizwa.

Izidakamizwa	Isigaba sezidakamizwa	I-Ampicillin	I-Amoxicillin
I-Warfarin	I-Anticoagulant	Yebo	Yebo
I-Allopurinol	I-Xanthine oxidase inhibitor (esetshenziselwa i-gout)	Yebo	Yebo
Izindlela zokuvimbela inzalo ngomlomo	Izindlela zokuvimbela inzalo ngomlomo	Yebo	Yebo
I-Probenecid	I-Uricosuric	Yebo	Yebo
UVivotif Bern	Umuthi wokugomela iTyphoid (bukhoma)	Yebo	Yebo
I-Bupropion	I-Aminoketone antidepressant	Yebo	Yebo
IMethotrexate	I-Antimetabolite	Yebo	Yebo
I-Magnesium citrate	I-saline laxative	Yebo	Yebo

Izexwayiso ze-ampicillin ne-amoxicillin

Izexwayiso ze-ampicillin ne-amoxicillin:

IClostridium difficile -uhudo oluhlobene kubikwe ukuthi kunama-antibiotic amaningi futhi kungahluka ngobunzima kusuka kuhudo oluncane kuye ekubulaliseni okubulalayo. Lesi sifo sohudo singenzeka ngesikhathi noma ngemuva kokusetshenziswa kwama-antibiotic (noma ezinyangeni ezimbalwa kamuva). Uma uhlangabezana nohudo, isicanucanu, ubuhlungu besisu, kanye / noma umkhuhlane, xhumana nomhlinzeki wakho wezempilo ngokushesha.
Uma unomlando wokungazwani nama-penicillin, ungathathi i-ampicillin noma i-amoxicillin.
Ukubikwa okukhulu, kwesinye isikhathi okubulalayo, kwe-hypersensitivity reaction (anaphylaxis) kubikwe ngama-penicillin. Lokhu kungenzeka nasezigulini ezelashwa nge-cephalosporin efana ne- cephalexin . Iziguli akufanele zinikezwe i-ampicillin noma i-amoxicillin uma kube nokusabela kwangaphambilini. Uma kwenzeka ukungezwani komzimba, i-ampicillin noma i-amoxicillin kufanele iyekwe ngokushesha futhi kufanele ufune ukwelashwa okuphuthumayo.
I-Ampicillin noma i-amoxicillin kufanele isetshenziselwe kuphela ukwelashwa ngegciwane. Ukusebenzisa i-antibiotic yokutheleleka ngegciwane ngeke kulaphe ukugula, futhi kungaholela ekumelaneni namagciwane.
Ukusetshenziswa isikhathi eside kwama-antibiotic kungaholela ekuthelelekeni kwefungal, okuzodinga ukwelashwa.

Ezinye izixwayiso ze-ampicillin:

Iziguli ezine-gonorrhea ne-syphilis nazo zidinga ukwelashwa kwe-penicillin (penicillin G) efanelekayo.
Ngaphandle kokwelashwa nge-ampicillin, isiguli sisengadinga inqubo yokuhlinzwa, ikakhulukazi ekuthelelekeni kwe-staphylococcal.

Imibuzo ebuzwa njalo mayelana ne-ampicillin vs. i-amoxicillin

Yini i-ampicillin?

I-Ampicillin iyi-beta-lactam, i-penicillin antibiotic, esetshenziselwa ukwelapha ukutheleleka okuningi kwamagciwane kubantu abadala nasezinganeni. I-Unasyn iqukethe i-ampicillin ne-sulbactam. Itholakala ngefomu lomjovo kuphela. I-Sulbactam iyi-beta-lactamase inhibitor, engezwa ku-ampicillin e-Unasyn ukuvimbela ukumelana namagciwane.

Yini i-amoxicillin?

I-Amoxicillin iyi-antibiotic ye-beta-lactam, ehlobene ne-penicillin, esetshenziselwa ukwelapha izifo ezahlukahlukene zamagciwane kubantu abadala nasezinganeni. I-Amoxicillin iyimithi elwa namagciwane evame kakhulu. I-Augmentin (equkethe i-amoxicillin ne-clavulanic acid) enye i-antibiotic ejwayelekile kakhulu enqunyelwe izifo eziningi zebhaktheriya. IClavulanic acid iyi-beta-lactamase inhibitor, engezwa ku-amoxicillin e-Augmentin ukusiza ukuvimbela ukumelana namagciwane.

Ngabe i-ampicillin ne-amoxicillin ziyafana?

I-Ampicillin ne-amoxicillin ziyefana kakhulu. Ayafana ngokufana futhi asesigabeni esifanayo semithi. Banemiphumela efanayo efanayo nokusebenzisana kwezidakamizwa, kepha ezinye izinkomba ezihlukile nokulinganisa okuhlukile. Ungafunda kabanzi ngemithi emibili kulwazi oluchazwe ngenhla.

Ingabe i-ampicillin noma i-amoxicillin ingcono?

Yomibili le mithi ingasebenza uma isetshenziswa yodwa; kodwa-ke, i-ampicillin isengozini enkulu yokumelana nemithi, ngakho-ke i-amoxicillin ibekwa kabanzi. Kodwa-ke, lokho akusho ukuthi kungcono, kukodwa, kepha kungenzeka kube yimpumelelo yokulwa namagciwane okuhloswe ukuba ahlasele. Uma noma imuphi umuthi usetshenziswa ngokuhlanganiswa ne-beta-lactamase inhibitor (i-Unasyn njengomjovo noma i-Augmentin njengomuthi womlomo), ukumbozwa ngama-antimicrobial kusebenza kakhulu, futhi ubungozi bokumelana nomuthi buphansi.

Ngingayisebenzisa i-ampicillin noma i-amoxicillin ngenkathi ngikhulelwe?

Yomibili le mithi ikhona isigaba sokukhulelwa B . Azikho izifundo ezanele nezilawulwa kahle kwabesifazane abakhulelwe. Umhlinzeki wakho wezokunakekelwa kwempilo uzolinganisa izingozi nezinzuzo lapho ethatha isinqumo sokuthi uyayidinga yini i-antibiotic, nokuthi imuphi umuthi olwa namagciwane ofanele uma ukhulelwe.

Ngingayisebenzisa i-ampicillin noma i-amoxicillin ngotshwala?

Ngenkathi i-ampicillin ne-amoxicillin kungaphikiswa notshwala, inothi ukuthi utshwala bungavimbela umzimba wakho ekulweni nesifo. Utshwala bungenza nemiphumela emibi yamathumbu ibe yimbi kakhulu. Kungcono ukugwema utshwala uze uzizwe ungcono.

Ingabe i-ampicillin iyimithi elwa namagciwane enamandla?

I-Ampicillin ingasebenza ngokulwa namagciwane ahlukahlukene adala izifo ezithile. Kodwa-ke, akubekiwe njengakuqala, ngenxa yenkinga ye- ukumelana lapho isetshenziswa yodwa njenge-ampicillin. Kuvame ukusetshenziswa (njengomjovo) esimweni sesibhedlela njenge-Unasyn, equkethe i-sulbactam ngaphezu kwe-ampicillin, ukusiza ukuvimbela ukumelana namagciwane.

Kufanele kuthathwe izinsuku ezingaki i-ampicillin?

Isibalo sezinsuku sincike ohlotsheni nobukhulu besifo futhi sizonqunywa ngumhlinzeki wakho wezokunakekelwa kwempilo. Imvamisa, i-ampicillin izothathwa izinsuku ezingaba yishumi kuya kwezingu-14. Qiniseka ukuthi uqeda yonke inkambo yama-antibiotic — ungayeki ngokungazelelwe ngisho noma uzizwa ungcono ngoba amabhaktheriya angabuya.

Yimaphi amagciwane abulala i-ampicillin?

I-Ampicillin isetshenziselwa ukwelapha ukutheleleka okuhlukahlukene kwamagciwane kubandakanya izifo ezithile zomgudu womchamo, izifo zokuphefumula, izifo ezithinta amathumbu kanye ne-meningitis. Bheka isigaba esingenhla Izimo ezilashwa yi-ampicillin kanye ne-amoxicillin ukuthola eminye imininingwane ngezinhlobo zebhaktheriya i-ampicillin elwa nazo kulezi zinhlobo zezifo.