Main >> Izidakamizwa Vs. Umngani >> I-Prednisolone vs. prednisone: Umehluko, ukufana, nokuthi yikuphi okungcono kuwe

I-Prednisolone vs. prednisone: Umehluko, ukufana, nokuthi yikuphi okungcono kuwe

Izidakamizwa Vs. Umngani

I-Prednisolone ne-prednisone yi-glucocorticoids ngayinye yokwenziwa esetshenziswa ezinhlobonhlobo zezifo ezibandakanya izinqubo zokuvuvukala nokuzimela. I-Prednisolone yi-metabolite esebenzayo ye-prednisone. I-Prednisone icutshungulwa esibindini iye ku-prednisolone ebese ikwazi ukuwela ulwelwesi lweselula. Uma usungaphakathi kweseli, i-prednisolone inokuhlangana okuphezulu kwama-cytoplasmic receptors, futhi ngokubopha, kuvimbela amaprotheni synthesis. Ekugcineni, isenzo esihlosiwe se-steroid ukuvimbela ukungena kwe-leukocyte endaweni yokuvuvukala, ukuphazamiseka ekusebenzeni kwabalamuli bempendulo yokuvuvukala, kanye nokucindezela izimpendulo zomzimba wokuzivikela.

Uyini umehluko omkhulu phakathi kwe-prednisolone ne-prednisone?

I-Prednisolone ngumuthi kadokotela osetshenziswa ezinkingeni zokuvuvukala nezizimele. I-metabolite esebenzayo ye-prednisone. Lapho nje iwele ulwelwesi lweseli, ivimbela ukungena kokumaka kokuvuvukala nokokuzivikela komzimba.

I-Prednisolone nayo ingabizwa ngamanye amagama okwakhiwa kwegama lomkhiqizo njenge-Prelone, Pediapred, Millipred, Orapred ODT, noma i-Pred-Forte. I-Prednisolone itholakala ngamaconsi e-ophthalmic (ukumiswa nesisombululo) nesisombululo somjovo. Ukwakhiwa komlomo kufaka izixazululo nokumiswa ku-5 mg / ml, 10 mg / ml, naku-15 mg / ml concentration. I-Prednisolone iyatholakala nakumathebulethi womlomo we-5 mg, kanye namaphilisi ahlukaniswa ngomlomo ku-10 mg, 15 mg, naku-30 mg amandla.

I-Prednisone umuthi kadokotela obuye usetshenziswe ezinhlobonhlobo zezifo zokuvuvukala kanye nezokuzivikela komzimba. I-Prednisone isuselwa ku-cortisone futhi kufanele ihlanganiswe nesibindi sibe yimo esebenzayo, i-prednisolone, ukuze iwele ulwelwesi lweselula.

IPrednisone nayo ingabizwa ngamagama ayo omkhiqizo iDeltasone noma iRayos. Itholakala ku-2.5 mg, 5 mg, 10 mg, 20 mg, naku-50 mg amaphilisi omlomo. Iphinde itholakale kwisisombululo somlomo.

Umehluko omkhulu phakathi kwe-prednisolone ne-prednisone
	I-Prednisolone	Prednisone
Isigaba sezidakamizwa	I-synthetic glucocorticoid / corticosteroid	I-synthetic glucocorticoid / corticosteroid
Isimo somkhiqizo / ejwayelekile	I-Brand ne-generic iyatholakala	I-Brand ne-generic iyatholakala
Ngubani igama lomkhiqizo?	I-Prelone, i-Millipred, i-Ordred ODT, noma i-Pred-Forte	Deltasone, Imisebe
Izidakamizwa zingena ngaziphi izinhlobo?	Amaconsi e-ophthalmic, isixazululo somjovo, isisombululo somlomo nokumiswa, amaphilisi okwehla ngomlomo nangomlomo	Ithebhulethi yomlomo, isisombululo somlomo
Uyini umthamo ojwayelekile?	40 mg kuya ku-60 mg inani ledosi lansuku zonke livame ukuhlukaniswa ngemithamo emi-2	Umthamo wokuqala we-5 mg kuya ku-60 mg nge-titration ngokususelwa ekuphenduleni nasekuxilongweni
Yelashwa isikhathi esingakanani?	Izinsuku ezintathu kuya kweziyishumi noma ngaphezulu kuye ngokuxilongwa	Izinsuku ezinhlanu kuze kube amasonto amaningana noma ngaphezulu kuye ngokutholakala kwesifo.
Ubani ovame ukusebenzisa umuthi?	Izinsana, izingane, nabantu abadala	Izinsana, izingane, nabantu abadala

Ufuna intengo engcono kakhulu ku-prednisolone?

Bhalisela izexwayiso zentengo ye-prednisolone bese uthola ukuthi intengo ishintsha nini!

Thola izexwayiso zentengo

Izimo eziphathwa i-prednisolone ne-prednisone

I-Prednisolone isetshenziselwa ukwelashwa okunhlobonhlobo kokuphazamiseka kokuvuvukala nokuzimela komzimba. Lokhu kufaka phakathi i-rheumatic, respiratory, allergic, endocrine, collagen, hematologic, emathunjini kanye nokuphazamiseka kwamehlo. I-Prednisone ihlanganiswe ne-prednisolone, ngakho-ke, uhlu lwayo lwezinkinga zokwelashwa ezihlosiwe luyafana.

Lawa ma-corticosteroids afakazelwe ukuthi asebenza kahle ku-rhinitis ye-allergen yonyaka, ukusabela okweqile, kanye ne-asthma ye-bronchial, okusiza ukunciphisa ukuvuvukala kwe-airway nokwenza lula inqubo yokuphefumula. I-Prednisolone ne-prednisone nazo ziyasebenza kwizilonda ezingekho emzimbeni ze-corneal marginal, i-herpes zoster ophthalmicus, nokuvuvukala kwangaphakathi kwamehlo. Amalungiselelo e-Prednisolone's topical ophthalmic angahle abonakale ewusizo ikakhulukazi ekuphazamisekeni kweso.

Ithebula elilandelayo, ngenkathi libanzi, kungenzeka lingabhali konke ukusetshenziswa kwale mithi emibili. Sicela uxhumane nomhlinzeki wakho wezokunakekelwa kwempilo ukuthola eminye imininingwane ngezinkomba zokusebenzisa.

Isimo	I-Prednisolone	Prednisone
I-hyperplasia yokuzalwa ye-adrenal	Yebo	Yebo
I-thyroiditis engasebenzi	Yebo	Yebo
Isifo samathambo	Yebo	Yebo
I-Ankylosing spondylitis	Yebo	Yebo
I-bursitis enamandla	Yebo	Yebo
I-synovitis ye-osteoarthritis	Yebo	Yebo
I-psoriatic arthritis	Yebo	Yebo
Uhlelo lupus erythematosus	Yebo	Yebo
I-seborrheic dermatitis enamandla	Yebo	Yebo
I-psoriasis enamandla	Yebo	Yebo
I-optic neuritis	Yebo	Yebo
Izilonda ezingezinhle ezisezingeni eliphansi	Yebo	Yebo
I-Herpes zoster ophthalmicus	Yebo	Yebo
Ukuvuvukala kwengxenye yangaphakathi	Yebo	Yebo
I-conjunctivitis yokungezwani komzimba	Yebo	Yebo
I-sarcoidosis yezimpawu	Yebo	Yebo
Ukuphefumula i-pneumonitis	Yebo	Yebo
Idiopathic thrombocytopenic purpura	Yebo	Yebo
I-ulcerative colitis	Yebo	Yebo
Ukukhula okunamandla kwe-Multiple Sclerosis	Yebo	Yebo

Ingabe i-prednisolone noma i-prednisone isebenza kangcono?

Lapho uqhathanisa ukusebenza kwe-prednisolone ne-prednisone, kubalulekile ukukhumbula ukuthi i-prednisone iyisandulela semetabolite esebenzayo, i-prednisolone. Lapho kuhlolisiswa ukusebenza kwanoma isiphi isidakamizwa, ukucatshangelwa kokuqala nokubaluleke kakhulu yikhono lesiguli lokuguqula i-prednisone ibe yi-metabolite yayo esebenzayo. I-Prednisone ihlanganiswa nesibindi i-prednisolone, futhi ijubane nobukhulu bokuguqulwa kuncike ekusebenzeni kwe-hepatic.

Abaphenyi kuqhathaniswa ukuguqulwa kwe-prednisone ezigulini ezikhombise ukukhubazeka kwe-hepatic ezigulini ezinomsebenzi ojwayelekile wesibindi. Ukuhlushwa kwe-plasma kwe-prednisolone bekuguquguquka ngokuphawulekayo ezigulini ezinesifo i-hepatic, ezinye iziguli zikhombisa cishe akukho ukuguqulwa komuthi. Abaphenyi baphetha ngokuthi kunokuhlukahluka okuningi kokuguqulwa kwe-prednisone, ngakho-ke iziguli ezinesifo i-hepatic kungenzeka zingakwazi ukuguqula ngokuthembekile i-prednisone ibe yi-metabolite yayo esebenzayo.

Iziguli ezinokusebenza kwesibindi okunempilo zingalindela ukuthi i-prednisolone noma i-prednisone iphumelele. I-Prednisolone ifaniswa ne-prednisone ku-mg kuya ku-mg basis. I-Prednisone iyatholakala kumaphilisi wedosi aphezulu, okwenza ukuphathwa kwamanani aphezulu kungabi nzima kangako. Ukwakhiwa kwePrednisolone kungancanyelwa kumuntu onenkinga yokusebenza kwesibindi okungasebenzi ukuze aqede ukukhathazeka ngokuguqulwa kwe-prednisone.

Ufuna intengo engcono kakhulu ku-prednisone?

Bhalisela izexwayiso zentengo ye-prednisone bese uthola ukuthi intengo ishintsha nini!

Thola izexwayiso zentengo

Ukuhlanganisa kanye nezindleko ze-prednisolone vs. prednisone

I-Prednisolone ngumuthi kadokotela ovame ukumbozwa ngezinhlelo zezohwebo nezeMedicare. Intengo emaphakathi yokuthengisa ye-prednisolone 15 mg / 5ml ingaba ngaphezulu kwama- $ 36 ngama-ounces ayisishiyagalombili amanzi. Ngesigqebhezana esivela ku-SingleCare, le ntengo yehla yaba ngaphansi kwama- $ 27.85.

I-Prednisone nayo iyimithi kadokotela evame ukuhlanganiswa yizinhlelo zombili zomshuwalense wezohwebo kanye neMedicare. Intengo emaphakathi yokuthengisa ye-prednisone icishe ibe ngama- $ 22 ngamathebulethi ayishumi angama-20 mg. Ungahle ukwazi ukuthola lo muthi ngemali engaphansi kuka- $ 4 ngesigqebhezana se-SingleCare.

Kubalulekile ukuqaphela ukuthi ezifundeni ezithile zezifo, ama-corticosteroids angeke ahlanganiswe ngaphansi kwenzuzo yezidakamizwa ze-Medicare, kepha angahlanganiswa ngaphansi kwe-Medicare Part B. Usokhemisi wakho anganikeza imininingwane ethe xaxa ngokutholakala.

	I-Prednisolone	Prednisone
Ngokuvamile embozwe umshwalense?	Yebo	Yebo
Imbozwe ngokujwayelekile yi-Medicare?	Yebo	Yebo
Umthamo ojwayelekile	8oz, 10 mg / ml uketshezi	10, 20 mg amaphilisi
I-Medicare copay ejwayelekile	Iyahluka kuya ngokwakhiwa nangohlelo	Ngokuvamile<$10 but may vary depending on the plan
Izindleko ze-SingleCare	$ 340- $ 500	$ 4- $ 6

Imiphumela emibi ejwayelekile ye-prednisolone vs. prednisone

I-Prednisone ihlanganiswa ne-prednisolone yayo esebenzayo ngesibindi, ngakho-ke imiphumela emibi engaba khona yomuthi ngamunye ibukelana.

IGlucocorticoids yaziwa ngokubangela ukungalingani oketshezi kanye ne-electrolyte, okungaholela ekugcineni i-sodium noketshezi, umfutho wegazi ophakeme, futhi kwezinye izimo, ukuhluleka kwenhliziyo okucinana. Ukuzuza kwesisindo kungumphumela ojwayelekile we-corticosteroids.

Ukusetshenziswa isikhathi eside kwe-steroids kunganciphisa ukukhula kwezingane, futhi ngenxa yalesi sizathu, ukusetshenziswa kwazo kufanele kukhawulelwe esikhathini esifushane ngangokunokwenzeka ukufeza ukuthethelelwa kwezimpawu.

Ama-glucocorticoids angaphazamisa ukuphendula komzimba ku-insulin. Iziguli ezincike ku-insulin ejojowe noma ezinye izidakamizwa ezilwa nesifo sikashukela kungadingeka zilungise umthamo wazo ngenkathi ziku-steroids. Isifo sikashukela singabona ukwanda kukashukela egazini labo noma kumthamo wesikhashana omfushane wama-steroids. Iziguli ezingezona isifo sikashukela ekwelashweni isikhathi eside kwe-steroid zingaba namathuba aphindwe kane okuthuthukisa isifo sikashukela.

Ithebula elilandelayo alihloselwe ukuthi libe uhlu olubanzi lwemiphumela emibi engaba khona ye-prednisone ne-prednisolone. Sicela uxhumane nosokhemisi noma udokotela wakho ukuthola uhlu oluphelele lwayo yonke imiphumela emibi.

	I-Prednisolone	Prednisone
Imiphumela emibi	Kusebenza?	Imvamisa	Kusebenza?	Imvamisa
Ukugcinwa kwamanzi	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Umfutho wegazi ophezulu	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Ukugcinwa kwesodium	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Ukwehluleka kwenhliziyo yokubopha	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Ukuzuza kwesisindo	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Ubuthakathaka bemisipha	Yebo	Akuchaziwe	Yebo	Akuchaziwe
I-osteoporosis	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Ukwephuka kwamathambo amade	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Isilonda se-Peptic	Yebo	Akuchaziwe	Yebo	Akuchaziwe
I-Pancreatitis	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Ukuhlukaniswa kwesisu	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Ukupholisa ukulimala kwesilonda	Yebo	Akuchaziwe	Yebo	Akuchaziwe
I-erythema ebusweni	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Ukujuluka okwengeziwe	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Ubuhlungu bekhanda	Yebo	Akuchaziwe	Yebo	Akuchaziwe
I-Vertigo	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Ukushintsha kwemizwelo	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Ukucindezelwa kokukhula	Yebo	Akuchaziwe	Yebo	Akuchaziwe
Ukumelana ne-insulin	Yebo	Akuchaziwe	Yebo	Akuchaziwe
I-Glaucoma	Yebo	Akuchaziwe	Yebo	Akuchaziwe

Umthombo: I-Prednisolone (I-DailyMed) Prednisone (I-DailyMed)

Ukusebenzisana kwezidakamizwa ze-prednisolone ne-prednisone

I-Prednisolone ne-prednisone zombili zingaphansi kwe-cytochrome P450 enzyme 3A4. Lokhu kuphakamisa amathuba okuhlangana kwezidakamizwa ngoba ezinye izidakamizwa eziningi nazo zenziwa uhlelo lwe-P450.

I-Itraconazole ne-ketoconazole yizinto ezivamile zokulwa nobulwelwe. Futhi angama-inhibitors anamandla ama-enzyme e-CYP 3A4. Le mithi, ngakho-ke, inciphisa imetabolism yesidakamizwa esisebenzayo, i-prednisolone. Lokhu kuholela ekwandeni kwe-serum concentrations ye-prednisolone. Ngenkathi imishanguzo ingahlinzekwa ndawonye isikhathi esifushane, iziguli kufanele ziqashwe ngokwanda kwemiphumela emibi ehlobene ne-glucocorticoid.

Ama-Corticosteroids asetshenziswa kakhulu ezigulini ezikwamanye ama-immunosuppressant agents. Umenzeli oyedwa angathinta izenzo zomunye, kodwa zisengasetshenziswa ndawonye uma ziqashwa ngokufanele. Isibonelo, i-Prolia (denosumab), eyi-ejenti yokuguqula i-immunosuppressant kanye ne-bone esetshenziselwa ukuphazamiseka kwamasosha omzimba kanye ne-osteoporosis, ingandisa ingozi yokutheleleka okunzima kweziguli ezikuma-corticosteroids. Ukusetshenziswa kwabo ngasikhathi sinye kwesinye isikhathi kuyadingeka, futhi iziguli kufanele ziqashwe ngeso lokhozi ukuthola izimpawu zokutheleleka.

I-Loop diuretics isiza ukuphatha isimo soketshezi emzimbeni ngokuhlunga i-potassium. Uma unikezwa nge-prednisolone noma i-prednisone, noma kunjalo, kukhona amandla okuthi umzimba ulahlekelwe yi-potassium eningi. Lokhu kungaba nemiphumela emibi ekusebenzeni kwenhliziyo. Iziguli okufanele zikuthathe ndawonye kufanele zibhekelwe isimo sazo se-electrolyte.

Ithebula elilandelayo alulona uhlu lwayo yonke imiphumela emibi engaba khona. Sicela uthinte umhlinzeki wakho wezokunakekelwa kwempilo ukuthola uhlu oluphelele.

Izidakamizwa	Isigaba Sezidakamizwa	I-Prednisolone	Prednisone
I-Baricitinib Dabrafenib Erdafitinib Ivosidenib Larotrectinib Tofacitinib Upadacitinib	I-Signal transduction inhibitors (i-STI): Ama-Immunosuppressants	Yebo	Yebo
I-Denosumab UNatalizumab UNivolumab Ocrelizumab USarilumab I-Siltuximab	Ama-Immunoglobulins: Ama-Immunosuppressants	Yebo	Yebo
Tacrolimus	I-Calcineurin inhibitor: I-Immunosuppressant	Yebo	Yebo
ICyclosporine	I-peptide ejikelezayo: I-Immunosuppressant	Yebo	Yebo
I-Aprepitant I-Fosaprepitant	Umphikisi we-NK1 receptor: Anti-nausea	Yebo	Yebo
Ketoconazole I-Itraconazole	Ama-antifungal we-Azole	Yebo	Yebo
Unyazi	IVasopressin analog	Yebo	Yebo
Diltiazem	Isivimbeli sesiteshi seCalcium	Yebo	Yebo
Isoniazid I-Rifampin	I-Antitubercular	Yebo	Yebo
Phenytoin	I-Anticonvulsant	Yebo	Yebo
I-Bumetanide UFurosemide I-Torsemide	I-Loop Diuretics	Yebo	Yebo
I-Aspirin Ibuprofen I-Naproxen I-Diclofenac UMeloxicam UCelecoxib	Ama-NSAID	Yebo	Yebo
I-Chlorthalidone I-Hydrochlorothiazide	I-Thiazide isisu	Yebo	Yebo

Izexwayiso ze-prednisolone ne-prednisone

Azikho izifundo ezilawulwa kahle ze-corticosteroids kwabesifazane abakhulelwe, ngakho-ke ukusetshenziswa kwabo ekukhulelweni kufanele kwenzeke kuphela lapho kusobala ukuthi inzuzo idlula noma iziphi izingozi. Izinsana ezizalwe ngomama abasebenzisa i-corticosteroids ngesikhathi sokukhulelwa kufanele zibhekwe nge-hypoadrenalism. Izimpawu zingafaka ukudla okuncane, ukuncipha komzimba, ukucasuka, noshukela ophansi wegazi.

I-Corticosteroids, ikakhulukazi ngemithamo ephezulu, izovimbela amandla omzimba wokukhiqiza amasosha omzimba lapho kunikezwa imigomo. Imithi yokugoma kungenzeka ingasebenzi ezigulini ezithola ama-steroids. Imishanguzo ebukhoma, efana nengxibongo, akufanele inikezwe iziguli ezithola ukwelashwa kwe-corticosteroid. Iziguli ezithatha ama-immunosuppressive agents zisengozini enkulu yokutheleleka emithini yokugoma ebukhoma.

Ama-Corticosteroids angafihla izimpawu zokutheleleka futhi anganciphisa ukutholakala kwezifo ezintsha. Ukusetshenziswa isikhathi eside kwe-prednisolone ne-prednisone kungaholela ekhathakheni naseglaucoma.

I-Prednisolone ne-prednisone zingashintsha imiphumela yokuhlolwa kwesikhumba noma okunye ukuhlolwa kokungezwani komzimba. Ukuze uthole imiphumela enembile kunazo zonke, ukwelashwa kwe-steroid kufanele kumiswe ezinsukwini ngaphambi kokwenza lezi zivivinyo.

Ama-steroid kufanele anikezwe kuphela isikhathi esifushane ngangokunokwenzeka ukufeza imiphumela oyifunayo. Uma ukusetshenziswa kwesikhathi eside kwe-steroids kuyadingeka kwezokwelapha, kufanele kugcinwe kumthamo ophansi kakhulu osebenzayo.

Imibuzo ebuzwa njalo mayelana ne-prednisolone vs. prednisone

Yini i-prednisolone?

I-Prednisolone iyi-synthetic glucocorticoid esetshenziselwa ukwelapha ukungezwani okuhlukahlukene kokuvuvukala nokuzimela. Itholakala njengethonsi leso, isisombululo esingajova, uketshezi lomlomo, ithebhulethi engaqedwa, nethebhulethi yomlomo. Isikhathi eselashwa kakhulu kunazo zonke izinsuku ezintathu kuya kweziyishumi zokwelashwa ngomlomo.

Yini i-prednisone?

I-Prednisone iyi-glucocorticoid ehlanganiswa nesibindi ifomu layo elisebenzayo, i-prednisolone. Ibuye isetshenziswe ezifweni eziningi zokuvuvukala nezizimele. I-Prednisone iyatholakala kumathebulethi womlomo nangendlela yokwenziwa kwezixazululo zomlomo. Ukusetshenziswa okuhle kwe-prednisone imvamisa kuyindlela yezinsuku ezinhlanu.

Ngabe i-prednisolone ne-prednisone ziyefana?

I-Prednisolone ne-prednisone zombili zenziwe ngama-glucocorticoids. I-Prednisone ihlanganiswa nesibindi iye ku-metabolite esebenzayo, i-prednisolone. Amandla abo okuqhathanisa nge-milligram ayalingana, kepha awawona umuthi ofanayo.

Ngabe i-prednisolone noma i-prednisone ingcono?

Yize yomibili le mithi isebenza ngokubonisa kwayo, i-prednisolone ingaba yisidakamizwa esithandwayo esigulini esinokukhubazeka kwesibindi. Iziguli ezinesifo se-hepatic kungenzeka zingakwazi ukuguqula ngokuthembekile i-prednisone ibe yi-prednisolone.

Ngingayisebenzisa yini i-prednisolone noma i-prednisone ngenkathi ngikhulelwe?

I-Prednisolone ne-prednisone yizigaba zobungozi bokukhulelwa C. Lokhu kusho ukuthi azikho izifundo zabantu ezilawulwayo ezifakazela ukuthi umuthi uphephile ekukhulelweni. Le mithi kufanele isetshenziswe kuphela lapho inzuzo ivelela ubungozi.

Ngingasebenzisa i-prednisolone noma i-prednisone ngotshwala?

Ukuphuza njalo utshwala kungathinta amandla omzimba okwenza i-prednisone ibe sesimweni sayo esisebenzayo. Utshwala kanye ne-glucocorticoids bobabili kungaba nemiphumela emibi ohlelweni lwamathumbu. Ukusetshenziswa kotshwala kuncishiswe kakhulu ngesikhathi sokwelashwa kwe-steroid.

Yini elingana ne-prednisone?

Imithamo ye-Prednisolone ne-prednisone ziyalingana ngemililitha kuya ekuqhathaniseni kwe-milligram. Ngamanye amagama, u-5 mg we-prednisolone unamandla njengo-5 mg we-prednisone. I-Prednisolone ne-prednisone zinamandla aphindwe kahlanu kune-hydrocortisone, kodwa inye kuphela yesithupha amandla e-dexamethasone.

U-prednisolone uthatha isikhathi esingakanani ukusebenzela ukuvuvukala?

I-Prednisolone, uma inikezwa ngomlomo, ifinyelela inani layo eliphakeme ngehora elilodwa kuya kwamabili. Ngenkathi iziguli zingabika ukukhululeka kwezimpawu emahoreni ambalwa, kungathatha izinsuku ezimbili kuya kwezintathu ngaphambi kokuba izimpawu zithinteke kakhulu, ngokuya ngesimo nobukhali.

Ingabe i-prednisone imbi ngenhliziyo yakho?

I-Prednisone yaziwa ngokubangela ukugcinwa kwe-sodium noketshezi, okungangeza ukucindezeleka enhliziyweni. Ezimweni ezimbi kakhulu, kungaholela ekuhlulekeni kwenhliziyo okucinana. Ngokusebenzisana kwayo nezidakamizwa ezinjenge-furosemide, i-prednisone ingadala ukulahleka kwenani elikhulu le-potassium, okwenza isiguli sibe ne-hypokalemic. Umsebenzi we-Cardiac kufanele ubhekwe uma iziguli zisezifundweni ezinde zokwelashwa kwe-steroid.