Main >> Izidakamizwa Vs. Umngani >> I-Terconazole vs. miconazole: Umehluko, ukufana, nokuthi yikuphi okungcono kuwe

I-Terconazole vs. miconazole: Umehluko, ukufana, nokuthi yikuphi okungcono kuwe

Izidakamizwa Vs. Umngani

Ukutheleleka ngemvubelo (i-vulvovaginal candidiasis) kuyinkinga ejwayelekile ethinta impilo yabesifazane. Abesifazane abahlangabezana nokungenwa imvubelo ngezikhathi ezithile noma kaningi bavame ukunikezwa umuthi wokubulala izinhlungu, njenge-terconazole noma i-miconazole. Lawa ma-antifungal asebenza ngezindlela ezifanayo ukusiza ekwelapheni izifo ezibangelwa imvubelo eyaziwa ngokuthi AmaCandida albicans .

I-Terconazole ne-miconazole yelapha ukutheleleka kwesitho sangasese sowesifazane ngokuphazamisa ulwelwesi lwama-fungal cell. Ngokuqondile, bavimba i-enzyme ebhekele ukudala i-ergosterol, ingxenye ebalulekile yokwakheka kolwelwesi lweseli. Ngaphandle kwe-ergosterol, iseli lesikhunta livuza okuqukethwe kwalo futhi ekugcineni liyafa.

Yize besesigabeni esifanayo semithi, i-terconazole ne-miconazole kunokunye umehluko ekusetshenzisweni nasekwakhiweni. Zingahluka futhi kuzindleko nokutholakala.

Uyini umehluko omkhulu phakathi kwe-terconazole ne-miconazole?

I-Terconazole igama elijwayelekile le-Terazol. Kungumuthi we-antifungal we-triazole owavunywa yi-FDA ngo-1987. Ngokungafani ne-miconazole, i-terconazole ingatholwa kuphela ngencwadi kadokotela. Itholakala ngo-0.4% no-0.8% kakhilimu wesitho sangasese sowesifazane kanye ne-80 mg suppository yesitho sangasese sowesifazane.

IMiconazole — eyaziwa nangokuthi igama layo lomkhiqizo, iMonistat — iyisidakamizwa se-imidazole antifungal esitholakala phezu kwekhawunta. Yaqale yamukelwa ngo-1974. IMonistat iza njengo-2% no-4% kakhilimu wesitho sangasese sowesifazane kanye no-1200 mg, 200 mg kanye no-100 mg suppository wesitho sangasese sowesifazane (Monistat Ovule). Ngokungafani ne-terconazole, i-miconazole iyatholakala ekwakhiweni komthamo owodwa.

Umehluko omkhulu phakathi kwe-terconazole ne-miconazole
	I-Terconazole	Miconazole
Isigaba sezidakamizwa	I-Antifungal	I-Antifungal
Isimo somkhiqizo / ejwayelekile	Uhlobo lomkhiqizo nohlobo olujwayelekile luyatholakala	Uhlobo lomkhiqizo nohlobo olujwayelekile luyatholakala
Ngubani igama lomkhiqizo?	I-Terazol	Monistat
Izidakamizwa zingena ngaziphi izinhlobo?	Ukhilimu wesitho sangasese sowesifazane I-suppository yesitho sangasese sowesifazane	Ukhilimu wesitho sangasese sowesifazane I-suppository yesitho sangasese sowesifazane Ithebhulethi ye-Buccal (ye-candidiasis yomlomo) Ukhilimu wezihloko (wesikhumba se-candidiasis)
Uyini umthamo ojwayelekile?	Ukhilimu wesitho sangasese sowesifazane: Umuntu ofaka isicelo esisodwa ngokugcwele nsuku zonke ngesikhathi sokulala I-suppository ye-Vaginal: I-suppository eyodwa ye-80 mg kanye nsuku zonke ngesikhathi sokulala	Ukhilimu wesitho sangasese sowesifazane: Umuntu ofaka isicelo esisodwa ngokugcwele nsuku zonke ngesikhathi sokulala I-suppository ye-Vaginal: I-1200 mg eyodwa, i-200 mg, noma i-100 mg suppository kanye nsuku zonke ngesikhathi sokulala
Yelashwa isikhathi esingakanani?	Izinsuku ezi-3 kuya kwezi-7	Usuku olungu-1 (umthamo owodwa) noma izinsuku ezi-3 kuya kwezi-7
Ubani ovame ukusebenzisa umuthi?	Abantu abadala abaneminyaka engu-18 nangaphezulu	Abantu abadala, intsha kanye nezingane ezineminyaka engu-12 nangaphezulu

Ufuna intengo engcono kakhulu ku-terconazole?

Bhalisela izexwayiso zentengo ye-terconazole bese uthola ukuthi intengo ishintsha nini!

Thola izexwayiso zentengo

Izimo eziphathwa yi-terconazole ne-miconazole

I-Terconazole ne-miconazole kuvunyelwe i-FDA ukwelashwa i-candidiasis yangasese , noma izifo zemvubelo yesitho sangasese sowesifazane. I-topical miconazole cream nayo ivunyelwe ukwelapha unyawo lomsubathi (tinea pedis), umbandamu (tinea corporis), ne-jock's itch (tinea cruris). Ukhilimu wesikhumba seMiconazole ungasetshenziswa ne-zinc oxide yokushaywa inabukeni okubangelwa imvubelo. I-thrush yomlomo, noma i-candidiasis emlonyeni, ingelashwa ngamaphilisi e-miconazole buccal, abekwa ngaphakathi emlonyeni ukuze ancibilike kancane.

Isimo	I-Terconazole	Miconazole
Ukutheleleka kwemvubelo yowesifazane (i-vulvovaginal candidiasis)	Yebo	Yebo
Unyawo lomsubathi	Ngaphandle kwelebula	Yebo
Isibungu	Ngaphandle kwelebula	Yebo
Ukulunywa kukaJock	Ngaphandle kwelebula	Yebo
Ukuqubuka kwe-diaper	Ngaphandle kwelebula	Yebo
I-thrush yomlomo	Ngaphandle kwelebula	Yebo

Ingabe i-terconazole noma i-miconazole iyasebenza kakhulu?

I-Terconazole (Yini i-Terconazole?) Ne-miconazole (Yini i-Miconazole?) Zombili zingama-antifungal asebenzayo we-candidiasis yangasese. Ukuthi udokotela ubeka i-terconazole noma i-miconazole kuncike emlandweni wakho wezokwelapha nasekuhloleni ukutheleleka.

Ngokuya ngokuhlaziywa kwemeta kusuka ku- Ukutheleleka Nokumelana Nemithi , i-terconazole ne-miconazole zinamandla afanayo ekwelapheni izifo zemvubelo yesitho sangasese sowesifazane. Ukuhlaziywa kubuyekeze izivivinyo zokwelashwa ezingaphezu kuka-40 ezingahleliwe ezibuye zahlola nokusebenza kwamanye ama-antifungal, kufaka phakathi i-fluconazole, i-clotrimazole, i-butoconazole, ne-tioconazole. Abaphenyi bathola ukuthi i-fluconazole, eyaziwa nangokuthi i-Diflucan, iyisidakamizwa esithandwayo sokutheleleka ngemvubelo esithweni sangasese sowesifazane.

Ku-blind-blind, okungahleliwe, isilingo se-multicenter , Iziguli ezingama-900 ezinesifo semvubelo sowesifazane sangasese ziphathwe nge-terconazole noma ukhilimu we-miconazole. Ngenkathi yomibili imishanguzo ikhonjiswa ukuthi iyasebenza nemiphumela engemihle, ukhilimu we-terconazole ubenezinga eliphakeme lokwelapha (i-87.9% yeqembu le-0.4% le-terconazole, i-83.8% leqembu le-0.8% le-terconazole, ne-81.3% leqembu le-2% miconazole) .

Okunye ukubuyekeza okuvela kumagazini i- Ukwelashwa Kwemitholampilo uphethe ngokuthi iziguli ezinesifo semvubelo sowesifazane sangasese zathola ukukhululeka okusheshayo ngo-0.4% we-terconazole cream kunalezo ezalashwa ngo-2% we-miconazole cream. Kodwa-ke, akukho mehluko obalulekile ngokwezibalo otholakele phakathi kokwelashwa ngama-suppositories angama-80 mg we-terconazole kanye nokwelashwa ngama-suppositories ayi-100 mg miconazole nitrate.

Funa iseluleko sezokwelapha kumhlinzeki wakho wezokunakekelwa kwempilo ngenketho yokwelashwa engcono kakhulu yecala lakho elithile.

Ufuna intengo engcono kumiconazole?

Bhalisela izexwayiso zentengo ye-miconazole bese uthola ukuthi intengo ishintsha nini!

Thola izexwayiso zentengo

Ukuhlanganisa kanye nezindleko ze-terconazole vs. miconazole

I-Terconazole itholakala kuphela ngemithi kadokotela. Iningi labantu lingathola umuthi kadokotela wezinsuku ezintathu noma wezinsuku ezi-7 kokhilimu ojwayelekile we-terconazole. Kodwa-ke, izindleko ezijwayelekile zokuthengisa ze-terconazole zingaphezu kwama- $ 50. Ngekhuphoni le-SingleCare terconazole, izindleko zingaba cishe ngama- $ 20 emakhemisi abambe iqhaza.

I-Miconazole itholakala kabanzi njengesidakamizwa esingaphezu kwe-the-counter (OTC). Imvamisa itholakala njengeMonistat ngomthamo owodwa, ukwelashwa kwezinsuku ezintathu, nezinsuku eziyi-7. Izindleko ezijwayelekile zokuthengisa ze-miconazole ngu- $ 18. Isigqebhezana se-SingleCare miconazole singanciphisa intengo ibe ngu- $ 13, yize uzodinga incwadi kadokotela ukusizakala Ukulondolozwa kwe-SingleCare kwezidakamizwa ze-OTC .

	I-Terconazole	Miconazole
Ngokuvamile embozwe umshwalense?	Yebo	Kuya ngecebo lakho lomshuwalense
Imbozwe ngokujwayelekile yi-Medicare?	Yebo	Kuya ngecebo lakho lomshuwalense
Umthamo ojwayelekile	1 umfakisicelo ogcwele kanye ngosuku	1 umfakisicelo ogcwele kanye ngosuku
I-Medicare copay ejwayelekile	$ 3– $ 39	$ 4– $ 53
Izindleko ze-SingleCare	$ 20 +	$ 13 +

Thola ikhadi lesaphulelo sekhemisi

Imiphumela emibi ejwayelekile ye-terconazole vs. miconazole

Imiphumela emibi kakhulu ehlotshaniswa nama-antifungal agents, afana ne-terconazole ne-miconazole, ayicasula eduze kwesiza sohlelo lokusebenza. Uma isetshenziswa phezulu, le mithi ingadala ukushiswa kwesitho sangasese sowesifazane, ukulunywa noma ukucasuka.

Eminye imiphumela emibi ingafaka ikhanda, ubuhlungu, noma umkhuhlane. Le miphumela ivame ukuba mncane futhi ihambe yodwa. Kodwa-ke, uma imiphumela emibi iba mibi noma iqhubeka, thintana nomhlinzeki wakho wezokunakekelwa kwempilo.

Imiphumela emibi ye-terconazole ne-miconazole ngokuyinhloko ibandakanya ukusabela okweqile komuthi noma ezinye izithako ezingasebenzi ekwakhiweni. Ukusabela okweqile kungabandakanya ukuqhuma okukhulu, ukuluma nokucasula.

	I-Terconazole	Miconazole
Umphumela oseceleni	Kusebenza?	Imvamisa	Kusebenza?	Imvamisa
Ukushisa, ukuluma nokucasuka ezungeze isiza sohlelo lokusebenza	Yebo	Akunjalo	Yebo	Akunjalo
Ubuhlungu bekhanda	Yebo	26%	Yebo	Akunjalo
Ubuhlungu bomzimba	Yebo	2.1%	Yebo	Akunjalo
Imfiva	Yebo	0.5%	Yebo	Akunjalo

Lokhu kungenzeka kungabi uhlu oluphelele lwemiphumela emibi engenzeka. Sicela ubheke udokotela wakho noma umhlinzeki wezokunakekelwa kwempilo ukuze ufunde kabanzi.
Umthombo: DailyMed ( I-Terconazole ), IDailyMed ( Miconazole )

Ukusebenzisana kwezidakamizwa kwe-terconazole vs. miconazole

Njengoba okhilimu be-terconazole kanye ne-miconazole besetshenziswa phezulu ngaphakathi nangaphakathi kwesitho sangasese sowesifazane, izidakamizwa ezisebenzayo azivamisile ukungena egazini. Lokhu kusho ukuthi ukuxhumana kwezidakamizwa akuvamile. Izimo eziningi zokuhlangana kwezidakamizwa zenzeka lapho lawa ma-antifungal agents athathwa ngomlomo.

Amaphilisi e-Miconazole buccal (i-Oravig) angaxhumana ne-warfarin futhi andise ingozi yokopha. Ukhilimu we-miconazole wesitho sangasese sowesifazane kanye nama-suppositories angasebenzisana nezindlela zokuvimbela inzalo zangaphakathi, ezithatha njenge NuvaRing , aqukethe i-ethinyl estradiol. Yize ukubaluleka komtholampilo kukuncane, i-miconazole ingakhuphula amazinga e-ethinyl estradiol emzimbeni.

Khuluma nodokotela wakho mayelana nokunye ukuxhumana kwezidakamizwa okungenzeka ne-terconazole noma i-miconazole.

Izidakamizwa	Isigaba Sezidakamizwa	I-Terconazole	Miconazole
I-Warfarin	Ama-anticoagulants	Akunjalo	Yebo
I-Ethinyl estradiol	Izinto zokuvimbela inzalo	Akunjalo	Yebo

* Xhumana nochwepheshe wezokunakekelwa kwempilo ngokunye ukusebenzisana kwezidakamizwa.

Izexwayiso ze-terconazole ne-miconazole

Labo abanokuzwela okwaziwayo kuzithako ze-terconazole noma okhilimu be-miconazole kufanele bagweme lawa ma-ejenti noma bawasebenzise ngokuqapha. Ngaphandle kwalokho, le mithi ingadala ukusabela okweqile kokugula.

Abesifazane ababhekene nobuhlungu beqolo, ubuhlungu besisu, umkhuhlane, amakhaza, isicanucanu, ukuhlanza, ukukhishwa kwesitho sangasese okunuka kabi, noma ukungakhululeki okuphindayo kwesitho sangasese sowesifazane kufanele basebenzise kuphela ama-antifungal we-azole ngokuholwa ngumhlinzeki wezokunakekelwa kwempilo. Lezi zimpawu zingakhombisa isimo esibi kakhulu esinkimbinkimbi ngezinye izinto, njengamasosha omzimba abuthakathaka noma isifo sikashukela.

Labo abahlangabezana njalo nokutheleleka kwemvubelo yesitho sangasese sowesifazane kufanele futhi babonane nochwepheshe wezokunakekelwa kwempilo ngaphambi kokuqala ukwelashwa okubulala amagciwane. Ukutheleleka njalo kwemvubelo kufaka phakathi lokho okwenzeka kanye ngenyanga noma kathathu ngaphezu kwezinyanga eziyisithupha.

Abesifazane kuma-antifungal we-intravaginal kufanele bagweme ucansi lwangasese, ama-tampon, ama-douches, ama-spermicides, noma eminye imikhiqizo yesitho sangasese ngesikhathi sokwelashwa.

Imibuzo ebuzwa njalo nge-terconazole vs. miconazole

Yini i-terconazole?

I-Terconazole i-ejenti elwa namagciwane elapha i-candidiasis ye-vulvovaginal. Itholakala njengokhilimu wesitho sangasese sowesifazane noma i-suppository. I-Terconazole iza nephakethe lezinsuku ezintathu lokwelashwa elibizwa nge-Terazol 3 kanye nephakethe lezinsuku eziyisikhombisa elibizwa nge-Terazol 7.

Yini i-miconazole?

I-Miconazole ngumuthi obulala amagciwane otholakala njengokhilimu wamakhanda, ukhilimu wesitho sangasese sowesifazane, i-suppository yesitho sangasese sowesifazane, kanye nethebulethi ye-buccal. Isetshenziselwa ukwelapha i-candidiasis ye-vulvovaginal. Kodwa-ke, ingaphatha nezifo zefungal ezibangelwa UCandida esikhunjeni nasemlonyeni.

Ngabe i-terconazole ne-miconazole ziyefana?

I-Terconazole ne-miconazole azifani. I-Terconazole isidakamizwa esinqanda uketshezi esitholakala kuphela ngencwadi kadokotela. I-Miconazole umuthi obulalayo we-imidazole otholakala nomuthi noma phezu kwekhawunta. IMiconazole nayo iza ngezinye izindlela futhi ivunyelwe ukwelapha ukutheleleka kwesikhumba nomlomo.

Ingabe i-terconazole noma i-miconazole ingcono?

Kokubili i-terconazole ne-miconazole kuyalinganiswa nokusebenza kahle lapho welapha i-yearel yesitho sangasese sowesifazane = i-noopener noreferrer nofollowrel = i-noopener noreferrer> izivivinyo zomtholampilo zikhombise imiphumela engcono nge-terconazole. Kodwa-ke, izicelo zomhlaba wangempela zizoxhomeka ekwahlulelweni komtholampilo kadokotela wakho, ukuqina kwesifo, nokuthi yini, uma ikhona, i-ejenti elwa nokubulala ozame ngaphambili. Abesifazane abaningi bangase bakhethe i-miconazole ngenketho yabo elula yomthamo owodwa.

Ngingayisebenzisa i-terconazole noma i-miconazole ngenkathi ngikhulelwe?

Ngesikhathi sokukhulelwa, i-terconazole ingamunzwa ivela esithweni sangasese futhi ingadala imiphumela emibi enganeni engakazalwa. Ngakho-ke, akunconywa phakathi ne-trimester yokuqala. Xhumana nomhlinzeki wezempilo ngaphambi kokusebenzisa i-terconazole noma i-miconazole ngenkathi ukhulelwe.

Ngingayisebenzisa i-terconazole noma i-miconazole ngotshwala?

Njengoba i-terconazole ne-miconazole zivame ukusetshenziselwa izihloko, banengozi ephansi yokuxhumana notshwala. Noma kunjalo, akukhuthazwa ngokujwayelekile ukuphuza utshwala ngenkathi ugula. Utshwala bungathinta ngokungaqondile ukuthi amasosha omzimba angalwa kanjani nezifo.

Uhlobo luni lwemvubelo i-terconazole ilapha?

I-Terconazole isebenza kuphela ekuthelelekeni kwesitho sangasese sowesifazane okubangelwa uhlobo lwemvubelo olubizwa ngokuthi UCandida . Akusebenzi ezinye izifo, njenge-bacterial vaginosis.

Uyini umuthi onamandla kunayo yonke wokutheleleka ngemvubelo?

Umuthi onamandla kunayo yonke wokutheleleka ngemvubelo umenzeli wokubulala ongowesigaba se-azole. Ukwelashwa okujwayelekile kokuzikhethela kungumthamo owodwa we-Diflucan (i-fluconazole). Ama-antifungal we-OTC afana ne-miconazole nawo ayasebenza ekuthelelekeni kwemvubelo okuncane, okungajwayelekile. Ngokutheleleka okukhulu kwemvubelo, umuthi we-antifungal womlomo ungadingeka.