Main >> Izidakamizwa Vs. Umngani >> I-Trintellix vs. Lexapro: Umehluko, ukufana, nokuthi yikuphi okungcono kuwe

I-Trintellix vs. Lexapro: Umehluko, ukufana, nokuthi yikuphi okungcono kuwe

Izidakamizwa Vs. Umngani

Abantu abadala baseMelika abangaphezu kwezigidi eziyi-16 ukudana (ukucindezeleka okukhulu), futhi abantu abadala abacishe babe yizigidi eziyi-7 banenkinga yokukhathazeka ejwayelekile. Imicimbi yakamuva efana nobhubhane lwe-COVID-19, ibe yi- umthombo wokukhathazeka kubantu abaningi.

I-Trintellix (i-vortioxetine) ne-Lexapro (i-escitalopram) yimithi emibili kadokotela esetshenziselwa ukucindezeleka. ILexapro nayo isetshenziselwa ukukhathazeka. Yomibili le mithi ivunywa yi-United States Food and Drug Administration (FDA).

I-Trintellix neLexapro bayingxenye yeqembu lemithi ebizwa ngama-SSRI (i-serotonin reuptake inhibitors ekhethiwe). Ama-SSRI asebenza ngokwandisa amazinga e-serotonin ebuchosheni, okusiza ekuthuthukiseni izimpawu zokucindezeleka. Yize iTrintellix neLexapro kungama-SSRIs womabili, anokunye umehluko, esizokuchaza ngezansi.

Uyini umehluko omkhulu phakathi kweTrintellix neLexapro?

I-Trintellix (i-vortioxetine) ngumuthi we-SSRI. Itholakala ngegama lomkhiqizo kuphela, ifomu lethebulethi. Ingasetshenziswa kubantu abadala kuphela. Akufundwanga ezinganeni. UTrintellix ekuqaleni wayebizwa ngeBrintellix, kepha i- igama lashintshwa ukugwema ukudideka ngomuthi we-antiplatelet obizwa ngeBrilinta.

ILexapro (escitalopram) iyi-SSRI. ILexapro iyatholakala kuzo zombili izinhlobo zohlobo lomkhiqizo nanjengethebhulethi noma isisombululo somlomo. ILexapro isetshenziswa kubantu abadala nasebusheni abaneminyaka engu-12 nangaphezulu ukucindezeleka, noma abantu abadala abaneminyaka engu-18 nangaphezulu ukukhathazeka.

Umehluko omkhulu phakathi kweTrintellix neLexapro
	I-Trintellix	I-Lexapro
Isigaba sezidakamizwa	I-SSRI (i-serotonin reuptake inhibitor ekhethiwe)	I-SSRI (i-serotonin reuptake inhibitor ekhethiwe)
Isimo somkhiqizo / ejwayelekile	Umkhiqizo	Umkhiqizo nokujwayelekile
Ngubani igama elijwayelekile?	I-Vortioxetine	I-Escitalopram
Izidakamizwa zingena ngaziphi izinhlobo?	Ithebhulethi	Ithebhulethi, isixazululo
Uyini umthamo ojwayelekile?	Qala ku-10 mg ngosuku bese ukhuphukela ku-20 mg ngosuku uma ubekezelela	5 mg, 10 mg, noma 20 mg kanye ngosuku
Yelashwa isikhathi esingakanani?	Iyahlukahluka	Iyahlukahluka
Ubani ovame ukusebenzisa umuthi?	Abantu abadala	Abantu abadala nentsha (iminyaka engu-12 nangaphezulu)

Ufuna intengo engcono ku-Trintellix?

Bhalisela izexwayiso zentengo yeTrintellix bese uthola ukuthi intengo ishintsha nini!

Thola izexwayiso zentengo

Izimo eziphathwe yiTrintellix neLexapro

I-Trintellix ikhonjisiwe ukwelapha ukucindezeleka okukhulu (MDD). Kuyasetshenziswa kwesinye isikhathi off-ilebula yesifo sokukhathazeka esijwayelekile.

ILexapro ikhonjiswe ukuthi yelapha i-MDD kubantu abadala nasebasha abaneminyaka eyi-12-17. ILexapro nayo ikhonjisiwe ekwelapheni ukukhathazeka kokukhathazeka okujwayelekile kubantu abadala.

Isimo	I-Trintellix	I-Lexapro
Isifo esikhulu sokucindezeleka (MDD)	Yebo	Yebo
Isifo sokukhathazeka esijwayelekile	Ngaphandle kwelebula	Yebo

Ingabe i-Trintellix noma i-Lexapro isebenza kangcono?

TO ukuhlaziywa kwe-meta (ukuhlaziywa kwezifundo eziningi) okushicilelwe ku-2018 kuhlolwe ama-anti-depressants angama-21. Kokubili i-Trintellix neLexapro zitholakale zisebenza kakhulu kunezinye izidakamizwa zokulwa nokucindezeleka. Bobabili babebekezelela kangcono kunamanye ama-anti-depressants.

TO funda eyenziwe ngumkhiqizi weTrintellix uphethe ngokuthi iTrintellix neLexapro zombili ziyizidambisi ezisebenza ngempumelelo. Ucwaningo luphinde lwabika ukuthi iTrintellix inesifo esiphakeme semiphumela ethile emibi, njengesicanucanu kanye nokunwaya kuneLexapro.

Umhlinzeki wakho wezokunakekelwa kwempilo angakunquma umuthi osebenza kahle kakhulu kuwe, kucatshangelwa izimo zakho zezokwelapha nomlando kanye nanoma iziphi izidakamizwa ozithathayo ezingasebenzisana neTrintellix noma iLexapro.

Ufuna intengo engcono kakhulu kuLexapro?

Bhalisela izexwayiso zentengo yeLexapro bese uthola ukuthi intengo ishintsha nini!

Thola izexwayiso zentengo

Ukuqhathaniswa kanye nezindleko zeTrintellix vs. Lexapro

I-Trintellix imbozwe yimishwalense eminingi kanye nezinhlelo zeMedicare Part D. Kodwa-ke, kungcono ukubheka ngohlelo lwakho ukuthola imininingwane ethile yokumboza. I-Trintellix itholakala kuphela ngegama lomkhiqizo. Kungabiza ngaphezu kwe- $ 500 ngamathebulethi angu- # 30, 20 mg. Ungasebenzisa isigqebhezana samahhala se-SingleCare ukunciphisa intengo ibe cishe ngama- $ 350.

ILexapro ivame ukumbozwa umshwalense kanye neMedicare Part D. Uhlobo olujwayelekile luvame ukuba ne-copay ephansi. Umkhiqizo wegama lomkhiqizo uvame ukuba ne-copay ephakeme kakhulu noma kungenzeka ungambozwa nhlobo. I-generic Lexapro ibiza cishe ama- $ 70 ngama- # 30, 10 mg generic tablets. Ikhadi le-SingleCare lingehlisa intengo ejwayelekile ibe ngu- $ 8.

	I-Trintellix	I-Lexapro
Ngokuvamile embozwe umshwalense?	Yebo	Yebo (okujwayelekile)
Imbozwe ngokujwayelekile yi-Medicare Part D?	Yebo	Yebo (okujwayelekile)
Umthamo ojwayelekile	30, 20 mg amaphilisi	30, 10 mg amaphilisi
I-Medicare copay ejwayelekile	$ 3- $ 14	$ 0- $ 30
Izindleko ze-SingleCare	$ 352- $ 365	$ 8- $ 40

Thola ikhadi lesaphulelo sekhemisi

Imiphumela emibi ejwayelekile yeTrintellix vs. Lexapro

Umphumela ovame kakhulu weTrintellix yisicanucanu, esivame ukuba mnene ukuba silinganiswe futhi sihlale cishe amasonto amabili. Eminye imicimbi emibi ejwayelekile ifaka phakathi imiphumela emibi yezocansi, isicanucanu, ukuqunjelwa, ukuhlanza, isifo sohudo, umlomo owomile, nesiyezi.

Imiphumela emibi kakhulu yeLexapro yikhanda, isicanucanu, izinkinga zocansi, ukozela nokuqwasha.

Ngomuthi ngamunye omusha noma ogcwalisiwe we-Trintellix noma i-Lexapro, uzothola umhlahlandlela wemithi oxoxa ngemiphumela emibi, izexwayiso, nolunye ulwazi olubalulekile.

Lolu akulona uhlu olugcwele lwemiphumela emibi. Eminye imiphumela emibi kungenzeka. Xhumana nomhlinzeki wakho wezokunakekelwa kwempilo ukuthola uhlu olugcwele lwemiphumela emibi engaba khona.

	I-Trintellix *	I-Lexapro
Umphumela oseceleni	Kusebenza?	Imvamisa	Kusebenza?	Imvamisa
Ubuhlungu bekhanda	Yebo	% akubikiwe	Yebo	24%
Isicanucanu	Yebo	21-32%	Yebo	18%
Ukuphazamiseka kokuchama / ukungasebenzi kahle kwezocansi	Yebo	16-34%	Yebo	14%
Uhudo	Yebo	7-10%	Yebo	8%
Ukuqunjelwa	Yebo	3-6%	Yebo	3%
Umlomo owomile	Yebo	6-8%	Yebo	9%
Ukozela	Akunjalo	-	Yebo	13%
Isiyezi	Yebo	6-9%	Yebo	5%
Ukuqwasha	Akunjalo	-	Yebo	12%

* imiphumela emibi incike esilinganisweni
Umthombo: DailyMed ( I-Trintellix ), IDailyMed ( I-Lexapro )

Ukusebenzisana kwezidakamizwa kweTrintellix vs. Lexapro

Ngoba zombili lezi zidakamizwa zisesigabeni esisodwa, zinokusebenzisana kwezidakamizwa okufanayo.

I-MAOI (monoamine oxidase inhibitors) ihlangana neTrintellix neLexapro. Ukusetshenziswa kwabo kufanele kwehlukaniswe ngezinsuku eziyi-14-21, kuya ngohlelo lokwelashwa ngakunye. Ukuhlanganiswa kwe-MAOI ne-Trintellix noma i-Lexapro kungakhuphula ubungozi be- isifo se-serotonin , isimo esiphuthumayo esisongela impilo ngenxa yokwakheka kwe-serotonin.

Ama-Triptans asetshenziselwa ukwelapha i-migraines, njenge-Imitrex (sumatriptan), kanye nezinye izidambisigungu, ezifana no-Elavil noma uCymbalta, akufanele zisetshenziswe ngokuhlangana ne-Trintellix noma i-Lexapro ngenxa yobungozi be-serotonin syndrome. Futhi, i-dextromethorphan ecindezelayo yokukhwehlela — etholakala eRobitussin-DM kanye neminye imikhiqizo eminingi yokukhwehlela nemikhiqizo ebandayo — kufanele igwenywe ngoba ingadala neserotonin syndrome uma ihlanganiswe neTrintellix noma iLexapro.

Eminye imishanguzo engasebenzisana neTrintellix noma iLexapro ifaka phakathi izidakamizwa ezingezona ukuvuvukala (ama-NSAID), ezinjenge-aspirin noma ibuprofen, nama-anticoagulants (ama-blood thinner), njenge-warfarin. Gwema utshwala lapho uthatha iTrintellix noma iLexapro.

Lolu akulona uhlu olugcwele lokusebenzisana kwezidakamizwa. Xhumana nomhlinzeki wakho wezokunakekelwa kwempilo ukuthola uhlu oluphelele lokuhlangana kwezidakamizwa.

Izidakamizwa	Isigaba sezidakamizwa	I-Trintellix	I-Lexapro
I-Phenelzine I-Rasagiline USelegiline I-Tranylcypromine	Ama-MAOIs	Yebo	Yebo
Utshwala	Utshwala	Yebo	Yebo
I-Rizatriptan I-Sumatriptan Zolmitriptan	Ama-Triptans	Yebo	Yebo
ISt. John's Wort	Isengezo	Yebo	Yebo
I-Warfarin	I-Anticoagulant	Yebo	Yebo
ICodeine I-Hydrocodone I-Morphine I-Oxycodone I-Tramadol	Ama-opioid	Yebo	Yebo
I-Dextromethorphan (kokukhwehlela okuningi nemikhiqizo ebandayo)	Ukukhwehlela okucindezelayo	Yebo	Yebo
I-Azithromycin I-Clarithromycin I-Erythromycin	Ama-antibiotic e-Macrolide	Akunjalo	Yebo
I-Aspirin Ibuprofen UMeloxicam UNabumetone I-Naproxen	Ama-NSAID	Yebo	Yebo
I-Desvenlafaxine I-Duloxetine I-Venlafaxine	Izidakamizwa ze-SNRI	Yebo	Yebo
Amitriptyline I-Desipramine Imipramine I-Nortriptyline	I-Tricyclic antidepressants	Yebo	Yebo
I-Alprazolam Clonazepam I-Diazepam	I-Benzodiazepines	Akunjalo	Yebo

Izixwayiso zeTrintellix neLexapro

Wonke ama-SSRI, kufaka phakathi iTrintellix neLexapro, anesixwayiso esibhokisi sokuzibulala. Izingane, intsha, kanye nabantu abadala abancane (abangafika eminyakeni engama-24 ubudala) abathatha imishanguzo yokulwa nengcindezi basengozini enkulu yokuzibulala nokuziphatha. Zonke iziguli zivuliwe imishanguzo elwa nokudangala kufanele ihlolwe ngokucophelela.

Ezinye izexwayiso zifaka:

I-Serotonin syndrome iyisimo esiphuthumayo esibi, esisongela ukuphila esidalwa ukwakheka kwe-serotonin eningi kakhulu. Iziguli ezithatha i-Trintellix noma i-Lexapro kufanele zibhekwe ngokucophelela izimpawu nezimpawu zesifo se-serotonin njenge-hallucinations, isifo sokuwa, ukushintsha kwengcindezi yegazi, kanye nokuxakaniseka. Iziguli kufanele zifune ukwelashwa okuphuthumayo uma kukhona kulezi zimpawu. Iziguli ezithatha ezinye izidakamizwa ezandisa amazinga e-serotonin (ama-triptans, ama-tricyclic antidepressants, i-fentanyl, i-lithium, i-tramadol, i-tryptophan, i-buspirone, i-dextromethorphan, i-amphetamines, i-St.
Ama-SSRI angandisa ingozi yokuphuma kwegazi. Ingozi iyanda ngokusetshenziswa okuhambisanayo kwe-aspirin, ama-NSAID, noma i-warfarin.
Ukwenza kusebenze imania noma i-hypomania kungenzeka. Ezigulini ezinesifo sokuphazamiseka kwengqondo okuguquguqukayo, i-antidepressant inganciphisa isiqephu esixubekile / somuntu.
Gwema ama-SSRI noma usebenzise ngokuqapha ezigulini ezinama-engeli amancane angalashwa angafakwanga (i-angle-closure glaucoma). I-Trintellix neLexapro zingadala izinkinga zombono ezinjengobuhlungu bamehlo, izinguquko zombono, ububomvu nokuvuvukala. Buza umhlinzeki wakho wezokunakekelwa kwempilo uma usengozini.
I-Hyponatremia (amazinga aphansi e-sodium) ngenxa yesifo se-secretion engafanele ye-antidiuretic hormone (SIADH) kungenzeka. Iziguli zingathola ikhanda, ubunzima bokugxila, ukukhubazeka kwememori, ukudideka, ubuthakathaka nokungazinzi, okungaholela ekuweni. Izimo ezinzima kakhulu zingenzeka. Iziguli kufanele zifune ukwelashwa okuphuthumayo uma kwenzeka izimpawu, futhi ziyeke i-SSRI.
Lapho uyeka iLexapro, izimpawu zokuhoxa ezinjengokuxokozela kungenzeka. Iziguli kufanele zisikhiphe kancane kancane lesi sidakamizwa futhi zingalokothi ziyeke ngokungazelelwe.
I-Trintellix ingathathwa ngokungazelelwe uma kunesidingo, kepha umenzi wayo uncoma i-taper emfushane ukugwema izimpawu ezinjengekhanda nokuqina kwemisipha. Umhlinzeki wakho wezokunakekelwa kwempilo angakweluleka ngendlela engcono yokuyeka iTrintellix noma iLexapro.
Ungashayeli noma usebenzise imishini uze wazi ukuthi iTrintellix noma iLexapro ikuthinta kanjani.
Khuluma nomhlinzeki wakho wezokunakekelwa kwempilo ngokusebenzisa i-Trintellix noma i-Lexapro uma unomlando wokuquleka.
Ezimweni ezingavamile, kube khona imibiko yokuqubuka kanye ne-allergic reaction / systemic anaphylaxis reaction ebulalayo. Uma uhlangabezana nokuqubuka noma izimpawu zokungezwani komzimba, yeka ukuthatha iTrintellix noma iLexapro bese ufuna ukwelashwa ngokushesha.
ILexapro ingadala ukwandiswa kwe-QT kanye ne-ventricular arrhythmia. Iziguli ezithile zisengozini enkulu ngenxa yezimo zezokwelapha noma eminye imithi. Buza umhlinzeki wakho wezokunakekelwa kwezempilo ukuthi ngabe iLexapro iphephile yini kuwe.
Sebenzisa iLexapro ngokuqapha ezigulini ezinezinkinga zezinso.

I-Trintellix noma i-Lexapro kufanele isetshenziswe kuphela ekukhulelweni uma inzuzo kumama inkulu kunengozi enganeni. Ukumisa umuthi kungadala ukubuyela ekucindezelekeni noma ekukhathazekeni. Ngakho-ke, iziguli kufanele zihlolwe ngamacala ngamacala. Umhlinzeki wakho wezokunakekelwa kwempilo angalinganisa ubungozi kanye nezinzuzo zokusebenzisa i-SSRI ngesikhathi sokukhulelwa. Ama-neonates adalulwe kuma-SSRI ku-trimester yesithathu athuthukise izinkinga ezidinga ukulaliswa esibhedlela isikhathi eside, ukwesekwa kokuphefumula, kanye nokudla nge-tube. Uma usuvele ukuTrintellix noma iLexapro futhi uthola ukuthi ukhulelwe, xhumana nomhlinzeki wakho wezokunakekelwa kwempilo ngokushesha.

Imibuzo ebuzwa njalo ngeTrintellix vs. Lexapro

Kuyini iTrintellix?

I-Trintellix iyi-SSRI, noma i-serotonin reuptake inhibitor ekhethiwe. Itholakala ngegama lomkhiqizo futhi isetshenziselwa ukwelapha ukudangala kubantu abadala.

Kuyini iLexapro?

ILexapro iyi-SSRI. ILexapro ingaphatha ukucindezeleka nokukhathazeka. Itholakala ngazo zombili izinhlobo ze-generic (escitalopram).

Ngabe iTrintellix neLexapro ziyefana?

I-Trintellix neLexapro bobabili basesigabeni se-SSRI semithi kadokotela. Ziyafana, kepha azifani ncamashi. Banokungafani okuthile, njengoba kuchaziwe ngenhla. Eminye imishanguzo ye-SSRI okungenzeka ukuthi uzwile ngayo ifaka phakathi uCelexa (citalopram), uLuvox (i-fluvoxamine), i-Paxil (i-paroxetine), i-Prozac (i-fluoxetine), ne-Zoloft (i-sertraline).

Esinye isigaba semithi okungenzeka ukuthi uke wezwa ngesigaba sezidakamizwa seSNRI, okubandakanya iCymbalta (duloxetine), i-Effexor (venlafaxine), nePristiq (desvenlafaxine).

Ngabe iTrintellix noma iLexapro ingcono?

Bona isigaba esingenhla ngokusebenza kahle-kunemininingwane emincane kakhulu eqhathanisa iTrintellix neLexapro ngqo. Ucwaningo lukhombisa ukuthi yomibili le mithi iyasebenza futhi iyabekezelelwa ngokufanayo, yize yomibili le mithi inemiphumela engemihle engaba inkinga kwabanye abantu, enjengesicanucanu noma imiphumela emibi yocansi.

Umhlinzeki wakho wezokunakekelwa kwezempilo anganquma ukuthi imuphi umuthi ongcono kuwe, ecabangela izimo zakho ezihlukile. Isibonelo, uma intengo iyisici esinqumayo, i-Lexapro ejwayelekile ingabiza kakhulu, futhi uzokwazi kakhulu ukulandela uhlobo lwemithi. Noma, uma imiphumela emibi yezocansi ingukukhathazeka, ungenza kangcono ngeTrintellix, engahle ibe nemiphumela emibi ngokocansi.

Ngingayisebenzisa iTrintellix noma iLexapro ngikhulelwe?

Xhumana nomhlinzeki wakho wezokunakekelwa kwempilo ukuthola izeluleko. Uzolinganisa izinzuzo zokuthatha i-anti-depressant uma kuqhathaniswa nobungozi enganeni. Ama-neonates avezwe kuma-anti-depressants athile, kufaka phakathi ama-SSRI, ku-trimester yesithathu yokukhulelwa, abe nezinkinga.

Uma usuvele uku-Trintellix noma i-Lexapro futhi uthola ukuthi ukhulelwe, thintana ne-OB-GYN yakho ngokushesha ukuthola izeluleko. Uma kunjalo ukuncelisa ibele , thintana ne-OB-GYN yakho futhi.

Ngingasebenzisa i-Trintellix noma i-Lexapro ngotshwala?

Cha. I-Trintellix noma i-Lexapro akufanele ithathwe ngotshwala ngoba inhlanganisela ingakhuphula ubungozi bokucindezeleka kokuphefumula (ukuphuza ukuphefumula, ukungatholi i-oksijini eyanele) futhi kwandise ukuthamba nokulala, futhi kuphazamise ukuqapha. Inhlanganisela nayo ingakhulisa ukukhathazeka nokudangala.

I-Trintellix ihluke kanjani kwamanye ama-anti-depressants?

I-Trintellix isebenza njengomphikisi, i-agonist, ne-agonist eyingxenye yama-receptors amaningi we-serotonin ukusiza izimpawu zokucindezeleka. Eminye imithi ekilasini le-SSRI, njengeLexapro, isebenza ngokwandisa umsebenzi we-serotonin ohlelweni lwezinzwa oluphakathi.

Ingabe i-Trintellix ibangela ukuzuza kwesisindo?

Umtholampilo izifundo ikhombise ukuthi iTrintellix ayithinti isisindo. Akukho mahluko ekushintsheni kwesisindo phakathi kwabantu abathathe i-Trintellix nabantu abathathe i-placebo (iphilisi elingasebenzi). Idatha yokumaketha ibalula ukuzuza kwesisindo kepha ayisho iphesenti labantu abahlangabezane nokuzuza kwesisindo. Xhumana nochwepheshe wezokunakekelwa kwezempilo uma ukukhathazeka ngesisindo kuyinkinga.