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Ayini amaketoni, futhi kungani eyingozi?

Ayini amaketoni, futhi kungani eyingozi?Imfundo Yezempilo

I-Ketosis, noma inqubo yokushisa amaketoni, isiphenduke igama elijwayelekile — sibonga i-carb ephansi ethandwayo Ukudla okune-ketogenic . Ngaphambi kokuba lokhu kudla kwezimfashini kuqhume ngaphesheya kwe-U.S., Ama-ketone ayaziwa kuphela kochwepheshe bezokunakekelwa kwezempilo nalabo abanesifo sikashukela — futhi kwakungeyona into enhle. Lapha, funda ukuthi ayini amaketoni, nokuthi angaba kanjani yingozi.

Ayini amaketoni?

Ama-ketone ngama-molecule ancibilikiswa ngamanzi akhiqizwa isibindi. Zakhiwa ngamafutha acid ngaphakathi komzimba lapho umzimba wakho ungakhiqizi i-insulin eyanele yokuguqula i-glucose ibe ngamandla, kusho UDavid Nazarian , MD, we-My Concierge MD eBeverly Hills.



iphilisi lokulawula inzalo elihamba phambili lezinduna futhi alikho inzuzo yesisindo

Kalula nje, ama-ketone (noma imizimba ye-ketone) angolunye uphethiloli olwenziwa esibindini sakho uma ingekho i-glucose eyanele (ushukela) wamandla. Lapho umzimba wakho ungenawo ushukela noma i-glucose eyanele yamandla, umzimba wakho udinga umthombo wamandla omusha. Umzimba wakho uzobe usushintshela ekwephuleni amafutha ukuze uthole amandla. Le nqubo yenziwa esibindini, lapho amafutha aguqulwa abe yikhemikhali elibizwa ngokuthi ama-ketone. Amaketoni, i-fatty acid, bese ekhishwa esibindini angene egazini lakho futhi asetshenziswe njengophethiloli wokugaya umzimba nokweseka ukusebenza kwemisipha.



Umzimba uqobo udinga amaketoni lapho amazinga e-insulin ephansi. Izibonelo zezikhathi lapho umzimba wakho ukhiqiza lo mthombo ohlukile wamandla kufaka phakathi ukuzila ukudla, ukudla ukudla okune-carb ephansi, noma ubusuku bonke lapho ulele.

Ngokungalawulwa thayipha isifo sikashukela esingu-1 , ama-ketone angakhiqizwa ngenxa yokushoda kwamaseli we-beta akhiqiza i-insulin emanyikwe noma ukungabi nawo umthombo ongaphandle, noma ongaphandle, we-insulin.



Ukukala ukukhiqizwa kwe-ketone kungenziwa ngokuhlolwa komchamo. Inani eliphephile lamaketoni emchameni liyahlukahluka kuye ngomuntu futhi kuya ngezimo zawo zempilo ezingaphansi. Ngenkathi abanye abantu bengaba namaketoni emchameni wabo futhi kuyinto ejwayelekile, abanye kufanele bakhathazeke uma kukhona i-ketone build-up ngoba lokhu kungakhombisa inkinga ebucayi kakhulu.

Iyiphi indlela enembile kunazo zonke yokulinganisa amaketoni?

Imitha yegazi noma itekisi lokuhlola umchamo wasekhaya lingasiza ekuhloleni amaketoni. Ikhithi yomchamo imvamisa iza nenkomishi nemichilo yokuhlola oyifaka emchameni. Indlela enembile kunazo zonke yokukala amaketoni, indinganiso yegolide kwezokunakekelwa kwempilo, kungokusebenzisa imitha ye-ketone yegazi (inothi: a imitha yeglucose ayilinganisi into efanayo).

Kufanele uhlole kaningi kangakanani amaketoni?

Abantu abasanda kutholakala benesifo sikashukela kufanele bahlole amazinga abo kabili nsuku zonke lapho betholakala okokuqala.Kulabo abangenaso isifo sikashukela, abafuna ukukala ama-ketone ngezizathu zokwehlisa isisindo, u-0.5 mmol / L egazini noma emchameni kusho ukuthi uzuze i-ketosis.



Ingabe amaketoni ayingozi?

Kulabo abangenaso isifo sikashukela, akuyona inkinga lapho umzimba wakho ukhiqiza amaketoni. Kodwa-ke, kubantu abanesifo sikashukela, ama-ketone angaba yingozi kakhulu. Lokhu kungenxa yokuthi umzimba awukwazi ukulawula i-insulin, i-glucagon, namanye ama-hormone kulabo abanesifo sikashukela.

Izinga eliphakeme lamaketoni angaba yingozi futhi angadala izingqinamba zezempilo. Izinga eliphakeme eliyingozi lamaketoni emizimbeni yethu livame ukuvela ezigulini ezinesifo sikashukela esincike ku-insulin esingazithathi i-insulin yaso, kusho uDkt. Igazi lakho liba ne-asidi kakhulu okuthi uma ingalungiswa iholele ekuqulekeni noma ekufeni.

Leli shadi lichaza izigaba zamakhemoni ezinempilo nezinengozi:



Amaketoni amabi Ngaphansi kwama-millimole ayi-0.6 ilitha (mmol / L)
Phansi ukuya ekulinganiseni 0.6 kuya ku-1.5 mmol / L
Phezulu 1.6 kuya ku-3.0 mmol / L
Phezulu kakhulu kukhulu kuno-3.0 mmol / L


Uma amazinga akho enesilinganiso esiphansi, shayela udokotela wakho ukuthi axoxe ngalawa mazinga ukuthola olunye ukuhlolwa. Ekuvakasheni kwakho, udokotela wakho uzokwenza umchamo noma ukuhlolwa kwegazi ukuthola amazinga we-ketone futhi enze ukuhlolwa kweshukela egazini. Kumazinga amakhulu kuno-1.6 kubalulekile ukufuna ukunakekelwa okuphuthumayo njengoba izimpawu zingasongela impilo.

Izimpawu zamaketoni aphezulu

Izimpawu ezihambisana namazinga aphezulu we-ketone ngokuvamile afaka:

  • Ukoma okungacimi
  • Ukuchama njalo
  • Umlomo owomile (xerostomia)
  • Amazinga kashukela aphezulu (angaphezu kuka-240)

Izimpawu ezingalashiwe zingaqhubekela phambili zibe nezimpawu ezingeziwe nezimbi kakhulu kufaka phakathi:



  • Ukudideka noma ubunzima bokugxila
  • Ukukhathala
  • Isicanucanu
  • Ukuhlanza
  • Isikhumba esomile noma esikhanyisiwe
  • Kunzima ukuphefumula
  • Ukuphefumula okubonakala ngephunga lezithelo
  • Ubuhlungu besisu

Isifo sikashukela ketoacidosis (DKA) siyinkinga enkulu yesifo sikashukela futhi ingaba ngumphumela wamazinga we-ketone angakhulunywanga. Lokhu kuzokwenza ukuthi igazi libe ne-asidi. Lolu wudaba olubucayi nolusongela impilo olungadala ukuvuvukala kobuchopho, ikhoma likashukela noma ukufa.

umuthi omuhle wokukhwehlela nekhala eligcwele

Kuthiwani uma amaketoni ami ephakeme kakhulu?

Uma amazinga akho ephezulu kakhulu ngokususelwa ekuhlolweni kwe-ketone, kubalulekile ukufuna ukwelashwa okuphuthumayo. Kungenzeka ube nezimpawu ezibalwe ngenhla futhi kungenzeka ukuthi kungaholela ku-DKA.

Uchwepheshe wezokwelapha uzokwelapha lesi simo ngaphakathi esibhedlela. Ezinye izindlela ezijwayelekile zokwelapha yilezi:



  • Uketshezi lwe-IV lokusiza isiguli ekutheni singabi namanzi ngenxa yokuchama kaningi
  • Ukufakwa esikhundleni kwe-Electrolyte ukusiza ukukhulisa ama-electrolyte alahlekile.
  • I-insulini isiza umzimba ukuguqula ubuyele ekusebenziseni i-glucose esikhundleni samaketoni ukuthola amandla.

Ukuphathwa kwesifo sikashukela kuyindlela engcono yokuvikela amazinga aphezulu, angenziwa ngu:

  • Ukuhlola amazinga eglucose egazini njalo
  • Ukudla ukudla okunempilo
  • Ukuhlolela ama-ketone uma ushukela wegazi ungaphezulu kuka-240 mg / dl
  • Ukuphatha imithamo efanele ye-insulin

Ngenkathi abantu abangenaso isifo sikashukela bengaba namaketoni emchameni, i-DKA inkinga kuphela kulabo abanesifo sikashukela.