Izidakamizwa ezijwayelekile zisanda kutholakala ngo-2019
Imininingwane YezidakamizwaSingabalandeli bemithi ejwayelekile kwaSingleCare. Yimithi engabizi kakhulu, futhi amanani aphansi asho ukuthi abantu abaningi bayakwazi ukukhokhela izidakamizwa abazidingayo ukuze bazizwe bengcono. Imithi engamashumi amane itholakale njengemithi ejwayelekile ngo-2019 — okusho ukuthi ukunamathela emithini ethe xaxa kanye nokonga okuningi kuwe. Lapha, sibheka ukuthi yimiphi imishanguzo emisha ejwayelekile nokuthi iqhathaniswa kanjani nozakwabo begama lomkhiqizo.
Uyini umehluko phakathi kwezidakamizwa ezijwayelekile nezegama?
Izidakamizwa zomkhiqizo wegama ziyimikhiqizo emakethwa futhi ithengiswe yinkampani eyakha lo muthi, kuchaza uJanet Fritsch, Pharm.D., Usokhemisi nomnikazi we Ikhemisi lasekhaya lase-Corner Drug eBaraboo, eWisconsin. Uqhubeka echaza ukuthi inkampani eyenza imithi ivunyelwe ukuthengisa lo muthi kuphela uma inelungelo lobunikazi. Lapho ilungelo lobunikazi seliphelelwe yisikhathi, ezinye izinkampani zikhululekile ukuthengisa uhlobo lwazo lomuthi ngezithako ezifanayo ezisebenzayo. Kungaleso sikhathi lapho abakwa-generic bangena khona. Imithi ejwayelekile yokuqala ukuvunywa kwenguqulo ejwayelekile eyenziwe yi-FDA. Imithi ejwayelekile egunyaziwe imakethwa yizinkampani ezinamagama, kodwa ngamanani ejwayelekile.
Kaningi ungaqaphela ama-generics ngamagama awo. Ngenkathi umuthi wegama lomkhiqizo uthengiswa ngaphansi kwegama eyanikezwa yinkampani eyenza imithi (okuvame ukuba lula ukubizwa futhi kuthengiswe), abakwa-generics babizwa ngegama lezithako (i) izithako zabo ezisebenzayo. Isibonelo, i-aspirin / dipyridamole yizithako ezisebenzayo ku- I-Aggrenox , umuthi ovimbela ukujiya kwegazi ngokweqile futhi unciphise ubungozi bokushaywa unhlangothi. Ngakho-ke lapho i-Aggrenox ithengiswa njenge-generic, ibizwa ngokuthi i-aspirin / dipyridamole.
Ngaphandle kwegama, awukho umehluko omkhulu. Imithi ejwayelekile kanye negama lomkhiqizo inezithako ezifanayo ezisebenzayo futhi isebenza ngokufanayo, ukuhlinzeka ngenzuzo efanayo yomtholampilo, kepha umuthi ojwayelekile awubizi kakhulu, kusho uLaurie Bond, CRNP, ongumhlengikazi Guqula Ukunakekelwa Okuyinhloko Okuqondile e-Annapolis, eMaryland.
Ngokusho kukaDkt Fritsch, abakhiqizi abajwayelekile kumele bakhombise i-FDA ukuthi bayalingana negama lomuthi wezidakamizwa.
Kungani ama-generic abiza ngaphansi kwezidakamizwa ezinegama lomkhiqizo?
Uma izidakamizwa ezijwayelekile nezegama ziyisithako esifanayo-esihlakaniphile, kungani ama-generic abiza kakhulu? Lapho ilungelo lobunikazi lomuthi seliphelile, izinkampani ezikhiqiza uhlobo olujwayelekile lomuthi ziyakwazi ukuwuthengisa ngengxenyana yentengo yegama lomuthi igama.
Imithi ejwayelekile ayibizi kakhulu ngoba umenzi bekungafanele aye ezindlekweni ezinkulu zokuqala ukuthuthukisa nokuthengisa umuthi, kusho uBond. Lapho ilungelo lobunikazi seliphelile, umuthi ungakhiqizwa ngezindleko eziphansi.
UDkt Fritsch uthi amanani aphansi kuma-generic nawo ahlobene nenani elikhulu lezinkampani manje ezikhiqiza lo muthi. Lapho nje ezinye izinkampani sezingakwazi, intengo ivamise ukwehla ngoba kunokuncintisana okuningi, uyachaza.
Yimiphi imishanguzo emisha ejwayelekile etholakale ngo-2019?
I- Ukuphathwa Kwezokudla Nezidakamizwa zase-U.S (FDA) igunyaza ama-generics amasha minyaka yonke. Kwesinye isikhathi ayatholakala emakhemisi ngemuva kokuvunywa. Kwezinye izikhathi, kukhona igebe phakathi kokuvunywa nokuthi umuthi utholakalaphi ukuthi uthengiswe. Kwesinye isikhathi umuthi usuvele unohlobo olujwayelekile, kepha i-FDA igunyaza umenzi owengeziwe ukuqinisekisa ukuncintisana okwanele ukugcina amanani entengo ephansi. Yonke imithi ejwayelekile eza emakethe kumele iqale ivunyelwe yi-FDA.
Nalu uhlu lwemithi efike emakethe njenge-generic kulo nyaka, ngokulandelana kwayo efika emakhemisi, ilandelwa izincazelo zomuthi ngamunye ojwayelekile.
| Igama elijwayelekile | I gama le-brand | Isimo | Usuku lokuvunyelwa olujwayelekile lwe-FDA | Idethi yemakethe |
| I-Pentamidine isethionate yesisombululo se-inhalation, i-300 mg / isitsha | I-NebuPent Powder yesisombululo se-inhalation | Ukuvimbela i-Pneumocystis jiroveci pneumonia (PJP) ezigulini ezisengozini enkulu ene-HIV | 04/24/2019 | 10/14/2019 |
| Isixazululo somlomo seDigoxin USP, 0.05 mg / mL | Isixazululo Somlomo Se-Digoxin | I-Atrial fibrillation nokwehluleka kwenhliziyo | 04/10/2019 | 04/10/2019 |
| I-Fosaprepitant yomjovo, 115 mg | Hlela | Isicanucanu nokuhlanza okuhambisana nokwelashwa ngamakhemikhali | 05/09/2019 | 05/09/2019 |
| Amathebulethi kaNabumetone USP, 500 mg, 750 mg, no-1,000 mg | Relafen | I-osteoarthritis nesifo samathambo | 08/30/2019 | 04/09/2019 |
| Amaphilisi wokukhishwa okubambezeleke we-Posaconazole, 100 mg | I-Noxafil | Ukuvimbela ukutheleleka kwezifo ezifweni ezisengozini enkulu | 08/21/2019 | 03/09/2019 |
| Ikhithi yokulungiselela i-technetium Tc99m mertiatide, 1 mg / vial | I-Technescan MAG3 | Ukuxilongwa kokungajwayelekile, ukwehluleka kwezinso, nokuvinjelwa komgudu womchamo | 12/07/2019 | 02/09/2019 |
| Amaphilisi e-morphine sulfate,15 mg no-30 mg | Amaphilisi e-morphine sulfate | Ubuhlungu obunzima nobunzima obungapheli | 07/22/2019 | 08/27/2019 |
| Amaphilisi we-Triamterene USP 50 mg, 100 mg | UDyrén | I-Edema | 08/19/2019 | 08/21/2019 |
| Ukhilimu we-Halcinonide USP, 0.1% | okuxekethile | Izimo zesikhumba ezivuthayo | 12/08/2019 | 08/15/2019 |
| Isixazululo se-Dapiprazole hydrochloride ophthalmic, 0.5% | Rev-Amehlo | I-Mydriasis ekhiqizwa yi-adrenergic (phenylephrine) noma ama-parasympatholytic (tropicamide) agents | 05/29/2019 | 07/31/2019 |
| Amaphilisi ePregabalin 25 mg, 50 mg, 75 mg, 100 mg, 150 mg, 200 mg, 225 mg, 300 mg | ILyrica | Ubuhlungu bemizwa, i-fibromyalgia, ukuquleka | 07/19/2019 | 07/22/2019 |
| I-Daptomycin yomjovo, i-350 mg / vial (50 mg / mL) | Cubicin | Ukutheleleka kwesikhumba negazi | 12/07/2019 | 07/16/2019 |
| Umjovo we-Icatibant, 30 mg / 3 mL (10 mg / mL) | I-Firazyr | Ukuhlaselwa okunamandla kwe-angioedema yefa | 07/15/2019 | 07/15/2019 |
| Amaphilisi e-Febuxostat, 40 mg no-80 mg | I-Uloric | I-Hyperuricemia ezigulini ezine-gout | 01/07/2019 | 05/07/2019 |
| Umjovo weCarboprost tromethamine USP,250 mcg / mL (1 ml) i-Vial yomthamo owodwa | I-Hemabate | Kukhipha isisu phakathi kwe-13thfuthi 20thamasonto okukhulelwa | 02/07/2019 | 03/07/2019 |
| Ijeli ye-Dapsone, 7.5% | I-Aczone | Izinduna | 06/26/2019 | 06/26/2019 |
| I-Sildenafil yokumiswa ngomlomo, i-10 mg / mL | Ukuvuselelwa | Umfutho wegazi ophezulu wegazi | 05/31/2019 | 05/31/2019 |
| Ama-capsules akhiphe ukubambezeleka okukhipha iMesalamine, 400 mg | I-Delzicol | I-ulcerative colitis | 09/05/2019 | 09/05/2019 |
| I-Penicillamine capsules USP, 250 mg | Inkomishi | Isifo sikaWilson, i-cystinuria, nesifo samathambo esibi | 07/05/2019 | 07/05/2019 |
| Umjovo we-Fentanyl citrate USP, 50 mcg (base) / 1 mL, 100 mcg (base) / 2 mL (50 mcg / mL), 250 mcg (base) / 5 mL (50 mcg / mL), 1,000 mcg (base) / 20 mL (50 mcg / mL), no-2,500 mcg (isisekelo) / 50 mL (50 mcg / mL) izitsha ezinezinga elilodwa | Umjovo we-Fentanyl citrate, noma i-Sublimaze | Ukuphumula kobuhlungu ngaphambi kokuhlinzwa, phakathi nangemva kokuhlinzwa | 03/05/2019 | 03/05/2019 |
| Amaphilisi eMifepristone, 200 mg | I-Mifeprex | Ukuqedwa kwezokwelapha kokukhulelwa kwe-intrauterine ngezinsuku ezingama-70 zokukhulelwa | 11/04/2019 | 01/05/2019 |
| Amaphilisi e-Ambrisentan, 5 mg, 10 mg | Letairis | Umfutho wegazi ophezulu wegazi | 03/28/2019 | 04/29/2019 |
| Amaphilisi e-Bosentan, 62.5 mg, 125 mg | I-Tracleer | Umfutho wegazi ophezulu wegazi | 04/26/2019 | 04/26/2019 |
| I-Valrubicin intravesical solution USP, 200 mg / 5 mL (40 mg / mL) emigqonyeni eyodwa yomthamo | I-Valstar | Umdlavuza wesinye | 04/19/2019 | 04/23/2019 |
| I-Solifenacin | Vesicare | Isinye esisebenza ngokweqile | 02/04/2019 | 04/22/2019 |
| I-Amoxicillin ne-clavulanate potassium yokumiswa ngomlomo i-USP, 125 mg / 31.25 mg nge-5 mL, 250 mg / 62.5 mg nge-5 mL | I-Augmentin | Izifo zokuphefumula, i-sinusitis, ukutheleleka kwesikhumba, ukutheleleka kwezindlebe, kanye nokutheleleka komchamo | 04/19/2019 | 04/19/2019 |
| Ukumiswa kweLotheprednol etabonate ophthalmic, 0.5% | I-Lotemax | Ukuvuvukala kwamehlo okubangelwa ukuhlinzwa noma ukutheleleka | 04/17/2019 | 04/18/2019 |
| I-gel Naftifine hydrochloride, 1% | UNafthini | Ukutheleleka kwezifo ezikhukhulayo | 03/20/2019 | 03/20/2019 |
| Valsartan | UDiovan | Umfutho wegazi ophakeme, isifo senhliziyo | 12/03/2019 | 12/03/2019 |
| I-Pyridostigmine bromide syrup, 60mg / 5mL | Isiraphu iMestinon | Ukwenza ngcono amandla emisipha ezigulini ezine-myasthenia gravis | 03/08/2019 | 11/03/2019 |
| Umjovo we-Fulvestrant, 250 mg / 5 mL (50 mg / mL) | Faslodex | Umdlavuza webele | 04/03/2019 | 04/03/2019 |
| Amaphilisi e-Aliskiren,150 mg, 300 mg | I-Tekturna | Umfutho wegazi ophakeme | 03/22/2019 | 04/03/2019 |
| Isixazululo se-Levofloxacin ophthalmic, 1.5% | Isixazululo se-Iquix ophthalmic | Izilonda ze-Corneal | 02/27/2019 | 01/03/2019 |
| Amaphilisi e-Deferiprone, 500 mg | Ferriprox | Ukugcwala kwensimbi ngenxa yokumpontshelwa igazi kweziguli ze-thalassemia | 02/08/2019 | 02/08/2019 |
| Amaphilisi e-Sevelamer hydrochloride, 400 mg, 800 mg | URenagel | Ukulawulwa kwe-phosphorus ezigulini ezinesifo esingapheliyo sezinso | 02/08/2019 | 02/08/2019 |
| Amaphilisi eVigabatrin USP, 500 mg | Sabril | Ukuquleka | 01/14/2019 | 06/02/2019 |
| Ukhilimu we-Acyclovir, 5% | Ukhilimu we-Zovirax | Izilonda ezibandayo | 04/02/2019 | 06/02/2019 |
| Amaphilisi we-Levomilnacipran anwetshiwe, 20 mg, 40 mg, 80 mg, 120 mg | Fetzima | Ukucindezeleka okukhulu | 04/02/2019 | 04/02/2019 |
| I-Wixela inhub (i-fluticasone propionate ne-salmeterol inhalation powder, i-USP) 100mcg / 50mcg, 250mcg / 50mcg, 500mcg / 50mcg | I-Advair Diskus | Isifo Somoya Ne-COPD | 01/30/2019 | 01/31/2019 |
| Isixazululo somlomo seSirolimus, 1 mg / mL | I-Rapamune | Ivimbela ukwenqatshwa komzimba kwiziguli zokufakelwa kwezinso | 01/28/2019 | 01/28/2019 |
1. I-Pentamidine isethionate yesisombululo se-inhalation
Igama lomkhiqizo: I-NebuPent powder yesisombululo se-inhalation
Isebenza kanjani: Lo muthi uvimbela inyumoniya (izifo ezithinta amaphaphu) kubantu abanamasosha omzimba abuthakathaka, ngenxa yesimo sezempilo esinjenge-HIV, noma abantu abathatha imishanguzo ecindezela amasosha omzimba.
2. Isixazululo somlomo seDigoxin USP
Igama lomkhiqizo: Isixazululo somlomo seDigoxin
Isebenza kanjani: IDigoxin ingeyesigaba semithi ebizwa nge-cardiac glycosides. Isetshenziselwa ukwelapha i-atrial fibrillation nokwehluleka kwenhliziyo.
3. I-Fosaprepitant yomjovo
Igama lomkhiqizo: Emend
Isebenza kanjani: I-Fosaprepitant umuthi osiza ukuvimbela isicanucanu nokuhlanza ezigulini ezelashwa ngamakhemikhali. Phambilini ibitholakala njengokujwayelekile kwifomu lethebulethi. Le nguqulo entsha ejwayelekile iyajova.
4. Izibhebhe zeNabumetone USP
Igama lomkhiqizo: Relafen
Isebenza kanjani: Amaphilisi e-Nabumetone angaphansi kwesigaba semithi esibizwa ngama-NSAID (izidakamizwa ezingezona ukuvuvukala ezingezona-steroidal). Zelapha ubuhlungu nokuqina okubangelwa i-osteoarthritis ne-rheumatoid arthritis. Lesi sidakamizwa besilokhu sitholakala njengesijwayelekile iminyaka. Lokhu kugunyazwa kuyisibonelo sokungenisa umkhiqizi ojwayelekile ojwayelekile. Yize i-FDA ivume isicelo se-genics sika-500 mg, 750 mg, kanye namathebulethi angu-1,000 mg, okwamanje atholakala kuphela emakethe ngamaphilisi angama-500 mg kanye nama-750 mg.
5. Amaphilisi okukhishwa okubambezelekile ePosaconazole
I gama le-brand: I-Noxafil
Isebenza kanjani: Okujwayelekile posaconazole kunqunyelwe ukuvikela ukutheleleka kwefungal kubantu abangenakunyakaziswa ngamandla, njengabantu abelashwa ngamakhemikhali. Itholakala kumaphilisi wokukhishwa okulibazisekile we-100 mg.
6. Ikhithi yokulungiselela i-technetium Tc99m mertiatide, 1 mg / vial
I gama le-brand:I-Technescan MAG3
Isebenza kanjani: Lena i-radiopharmaceutical esetshenziselwa izithombe ukusho uma izitho ezithile emzimbeni wakho zisebenza kahle.
7. Amaphilisi e-morphine sulfate
Igama lomkhiqizo: Amaphilisi e-Morphine sulfate
Isebenza kanjani: Amaphilisi e-morphine sulfate Kunqunyelwe ukwelapha ubuhlungu obunzima futhi obungapheli. Ngoba iyi-opioid enamandla okungezelela, iziguli kumele ziqale zibonise ukuthi azikwazi ukulawula ubuhlungu bazo neminye imithi.
8. Amaphilisi we-Triamterene
I gama le-brand: UDyrén
Isebenza kanjani: Odokotela banikeza i-triamterene ukwelapha i-edema ehambisana nezimbangela eziningi, kufaka phakathi ukwehluleka kwenhliziyo okucinanayo, ukuqina kwesibindi, i-nephrotic syndrome, nezinye izimo.
9. Ukhilimu we-Halcinonide USP
Igama lomkhiqizo: Halog
Isebenza kanjani: Odokotela banquma le steroid yama-topical ukwelapha ukuvuvukala nokushaywa okubangelwa yizimo eziningi zesikhumba ezifana ne-eczema, i-psoriasis, kanye ne-allergen reaction.
10. IDapiprazole
Igama lomkhiqizo: Rev-Eyes
Isebenza kanjani: Lawa maconsi wamehlo anqunyelwe ukwelapha isimo esibizwa nge-myatriasis eyenziwe iatrogenically, engenzeka lapho isiguli sithatha izidakamizwa ze-phenylephrine noma i-tropicamide.
11. IPregabalin
I gama le-brand: ILyrica
Isebenza kanjani: Lesi sidakamizwa sisetshenziselwa ukwelapha ubuhlungu bezinzwa kusuka ezimeni ezahlukahlukene, izimpawu ze-fibromyalgia, nokusiza ukuvimbela ukubanjwa okuthile.
12. I-Daptomycin yomjovo
I gama le-brand: Cubicin
Isebenza kanjani: Lo muthi welapha izifo zesikhumba nezegazi kubantu abadala. Phambilini bekuvunyelwe yiUFresenius Kabi. Kulo nyaka, i-Accord Healthcare ithole imvume.
13. Umjovo we-Icatibant
I gama le-brand: I-Firazyr
Isebenza kanjani: Umjovo we-Icatibant uphatha ukuhlaselwa okunamandla kwe-angioedema yefa (HAE). Ingasetshenziswa kuphela kubantu abadala abaneminyaka engu-18 nangaphezulu.
14. Amaphilisi e-Febuxostat
I gama le-brand: I-Uloric
Isebenza kanjani: Odokotela babeka i-febuxostat ukusiza ukuphatha i-hyperuricemia (i-uric acid ephezulu egazini) engahle yenzeke ezigulini ezine-gout. Lesi sidakamizwa singabekwa kuphela kubantu abadala.
15. Umjovo weCarboprost tromethamine
Igama lomkhiqizo: Hemabate
Isebenza kanjani: I-Carboprost tromethamine isidakamizwa esisetshenziselwa ukuqeda ukukhulelwa phakathi kwe-13thfuthi 20thisonto. Kuyakhonjiswa nokwelashwa kokopha kwangemva kokubeletha ngenxa ye-atony yesibeletho (isimo esisongela impilo esingenzeka ngemuva kokubeletha) esingaphendulanga ezindleleni ezijwayelekile zokuphatha.
16. Ijeli le-Dapsone
Igama lomkhiqizo: Aczone
Isebenza kanjani: I-Dapsone iyi-gel engasetshenziswa ngokwezihloko ukwelapha induna vulgaris. Ingasetshenziswa kuphela yiziguli ezineminyaka engu-12 nangaphezulu.
17. I-Sildenafil yokumiswa ngomlomo, i-10 mg / mL
I gama le-brand: Ukuvuselelwa
Isebenza kanjani: Leli fomu le-sildenafil ukumiswa ngomlomo, okusho ukuthi ulithatha njengoketshezi. Iphatha izinhlobo ezithile ze-pulmonary arterial hypertension (PAH) kubantu abadala ukwenza ngcono ikhono lokuzivocavoca umzimba nokugcina isimo singabi sibi kakhulu.
18. UMesalamine amaphilisi okukhipha okubambezelekile
I gama le-brand: I-Delzicol
Isebenza kanjani: I-Mesalamine isiza ekwelapheni nasekuphatheni i-ulcerative colitis ezigulini ezinhlanu nangaphezulu.
19. Amaphilisi we-penicillamine
Igama lomkhiqizo: Cuprimine
Isebenza kanjani: Lesi sidakamizwa sisetshenziselwa ukwelapha ukuphazamiseka okuningana, kufaka phakathi isifo sikaWilson kanye ne-cystinuria. Kungabekwa futhi ezigulini ezinesifo samathambo esibi, esisebenzayo esihlulekile ukuphendula esivivinyweni esanele sokwelashwa okuvamile.
20. Umjovo we-Fentanyl citrate USP
Igama lomkhiqizo: Umjovo we-Fentanyl citrate USP, Sublimaze
Isebenza kanjani: Le yi-ejenti enamandla kakhulu yokusiza ubuhlungu be-narcotic esetshenziswe ngaphambi kokuhlinzwa, phakathi ne-anesthesia, nangesikhathi sokululama ngemuva kokuhlinzwa.
21. Amaphilisi e-Mifepristone
Igama lomkhiqizo: Mifeprex
Isebenza kanjani: Lo muthi uyasetshenziswa (ngokuhlanganiswa nomunye umuthi obizwa nge-misoprostol) we ukukhishwa kwezisu ezinsukwini zokuqala ezingama-70 zokukhulelwa . Kuvimba ukukhiqizwa kwe-hormone progesterone, okudingekayo ukugcina ukukhulelwa okunempilo, kumama okhulelwe.
22. Amaphilisi e-Ambrisentan
Igama lomkhiqizo: Letairis
Isebenza kanjani: I-Ambrisentan inqunyelwe ukuphatha i-PAH (uhlobo lomfutho wegazi ophakeme ohilela uhlangothi lwangakwesokudla senhliziyo nemithambo ehambisa igazi emaphashini). Kungathuthukisa ikhono leziguli lokuzivocavoca nokugcina i-PAH ingabi kubi.
23. Amaphilisi e-Bosentan
Igama lomkhiqizo: Tracleer
Isebenza kanjani: Lo muthi uphatha i-PAH futhi ungabekelwa abantu abadala nezingane okungenani ezineminyaka emithathu ubudala.
24. Isixazululo se-Valpubicin intravesical USP
I gama le-brand: I-Valstar
Isebenza kanjani: Odokotela banikeza i-chemotherapy drug valrubicin intravesical (ifakwa esinyeni ngesixazululo se-catheter) ukwelapha uhlobo oluthile lomdlavuza wesinye obizwa nge-carcinoma in situ. Kunqunywa kuphela uma isiguli singakwazi ukuhlinzwa ukuze kususwe konke noma ingxenye yesinye. Kodwa-ke, kusebenza kuphela kwesinye seziguli ezinhlanu. Imvamisa isetshenziswa ngokuhlangana namanye amakhemikhali.
25. ISolifenacin
I gama le-brand: Vesicare
Isebenza kanjani: Odokotela babeka i-solifenacin ukwelapha isinye esisebenza ngokweqile. Lo muthi ekuqaleni wawenziwe ngefomu lomkhiqizo ngu-Astellas Pharma, inkampani yaseJapan. Kulo nyaka, Teva Pharmaceuticals, Alembic Pharmaceuticals, kanye neGlenmark Pharmaceuticals bonke bamemezele Ukwethulwa kwe-U.S. Kwamaphilisi e-solifenacin succinate , ejwayelekile ye-Vesicare.
26. I-Amoxicillin ne-clavulanate potassium yokumiswa ngomlomo kwe-USP
Igama lomkhiqizo: Augmentin
Isebenza kanjani: Le ngenye yama-antibiotic ajwayelekile atholakalayo, asetshenziselwa ukwelapha izifo ezithinta ukuphefumula, ukutheleleka nge-sinus, ukutheleleka kwezindlebe, ukutheleleka kwesikhumba, kanye nokutheleleka komchamo. Uhlobo olujwayelekile luvunyiwe ngaphambilini. Kulo nyaka, i-Aurobindo Pharma Limited ithole imvume ngohlobo lomuthi.
27. Loteprednol etabonate
I gama le-brand: I-Lotemax
Isebenza kanjani: ILoteprednol etabonate yehla ngeso le-corticosteroid. Kunqunyelwe ukwelapha ukuvuvukala kwamehlo okubangelwa ukuhlinzwa, izifo ezithile, ukungezwani komzimba nezinye izimo.
28. I-Naftifine hydrochloride
Igama lomkhiqizo: Naftin
Isebenza kanjani: INaftifine iza ifomu lejeli. Kungumuthi we-antifungal osetshenziswe esikhumbeni ukwelapha unyawo lomsubathi, i-jock itch, i-ringworm, nezinye izifo zesikhumba sefungal.
29. UValsartan
I gama le-brand: UDiovan
Isebenza kanjani: IValsartan yisidakamizwa esisetshenziselwa ukwelapha umfutho wegazi ophakeme kanye nokwehluleka kwenhliziyo okucinana. Iphinde isetshenziswe ezigulini ezithile ukunciphisa ukufa kwabantu ngemuva kokuhlaselwa yisifo senhliziyo. Phambilini yayikhishwa njengomuthi ojwayelekile ngo-2016. Kodwa-ke, i-FDA yakhipha phambilini ikhumbula umuthi ojwayelekile ovela kubakhiqizi abaningana kusukela ehlobo eledlule ngenxa yokungcola ngekhemikhali eliyingozi (ukungcola kwe-nitrosamine, i-NDMA). Lokhu kwaholela ekushodeni ezweni lonke. Ukunciphisa ukushoda, i- I-FDA ivume uhlobo olusha olujwayelekile lwe-valsartan ngoMashi walonyaka.
30. I-Pyridostigmine isiraphu ye-bromide
I gama le-brand: Mestinon isiraphu
Isebenza kanjani: Lesi sidakamizwa sithuthukisa amandla emisipha ezigulini ezinesifo semisipha esibizwa ngokuthi i-myasthenia gravis.
31. Umjovo we-Fulvestrant
Igama lomkhiqizo: Faslodex
Isebenza kanjani: Umjovo we-Fulvestrant, lapho uphathwa wedwa, ungaphatha izinhlobo ezithile zomdlavuza webele kwabesifazane abangemva kokuya esikhathini abangakaze bathole ukwelashwa kwe-endocrine. Kwesinye isikhathi ingasetshenziswa njengokwelashwa okuhlanganisiwe nomunye umuthi womdlavuza webele othuthukile noma we-metastatic kwabesifazane abanesifo esiqhubeka nokukhula ngemuva kokwelapha i-endocrine.
32. I-Aliskiren
Igama lomkhiqizo: Tekturna
Isebenza kanjani: I-Aliskiren iyi-renin inhibitor, esetshenziselwa ukwelapha umfutho wegazi ophezulu. Isebenza ngokunciphisa i-renin emzimbeni wakho. URenin unciphisa imithambo yegazi futhi akhuphule umfutho wegazi.
33. Isixazululo se-ophofalmic se-Levofloxacin
Igama lomkhiqizo: Isixazululo se-Iquix ophthalmic
Isebenza kanjani: Isixazululo se-ophofalmic se-Levofloxacin welapha i-corneal ulcer ebangelwa igciwane elithile.
34. Amaphilisi e-Deferiprone
Igama lomkhiqizo: Ferriprox
Isebenza kanjani: I-Deferiprone iyingxenye yesigaba semithi ebizwa nge-iron chelators. Isebenza ngokuzinamathisela ku-ayina emzimbeni wakho bese isiza umzimba wakho ukukhipha insimbi eyengeziwe emchameni wakho. Lo muthi unikezwa abantu abanesifo esithile segazi okuthiwa yi-thalassemia. Kwesinye isikhathi, abantu abane-thalassemia bane-iron eningi kakhulu emizimbeni yabo ngenxa yokumpontshelwa igazi njalo. (Ukumpontshelwa igazi kuyadingeka kubantu abanenkinga yegazi, kodwa futhi kuletha insimbi eyengeziwe emzimbeni.) Kubalulekile ukukhipha i-ayina eyengeziwe ngoba amazinga aphezulu ensimbi angadala izinkinga zempilo, njengesifo sesibindi, ukwehluleka kwenhliziyo, nesifo sikashukela.
35. Amaphilisi e-Sevelamer hydrochloride
Igama lomkhiqizo: Renagel
Kusebenza kanjani: Odokotela banikeza i-sevelamer ukulawula amazinga e-phosphorus egazini ezigulini ezinesifo esingapheliyo sezinso (CKD) esise-dialysis. Ukuphepha kwalesi sidakamizwa kubantu abane-CKD abangekho ku-dialysis akukaze kufundwe.
36. Amaphilisi eVigabatrin
Igama lomkhiqizo: Sabril
Isebenza kanjani: IVigabatrin isetshenziselwa ukwelashwa kokuquleka okuyinkimbinkimbi okuyingxenye (CPS) ezigulini ezineminyaka engu-10 nangaphezulu ezingaphendulanga ngokwanele kwezinye izindlela zokwelashwa ezihlukile.
37. I-Acyclovir ukhilimu
I gama le-brand: Zovirax ukhilimu
Isebenza kanjani: Lokhu umuthi ojwayelekile isetshenziselwa ukwelapha izilonda ezibandayo eziphindaphindayo. Kungabekelwa kuphela abantu abadala kanye nentsha abaneminyaka engu-12 nangaphezulu abangenayo i-immune system engafanele.
38. Ama-capsule akhishwe isikhathi eside e-Levomilnacipran
Igama lomkhiqizo: Fetzima
Isebenza kanjani: ILevomilnacipran ingeyesigaba sezidakamizwa esibizwa nge-serotonin ne-norepinephrine reuptake inhibitors (SNRIs). Lokho kusho ukuthi kwandisa inani le-neurotransmitters serotonin ne-norepinephrine ebuchosheni ukuze kusize ukukhulisa imizwa emihle nokunciphisa imizwa yokudabuka nokudangala. Isetshenziselwa ukwelapha i-Major Depression Disorder.
39. Uyayixoxa indaba
I gama le-brand: I-Advair Diskus
Isebenza kanjani: Lesi sidakamizwa, okuyi hit emakethe njengoba ejwayelekile ngoJanuwari walo nyaka, kwenzelwa ukwelashwa kwesifuba somoya nesifo samaphaphu esingamahlalakhona (COPD).
40. Isixazululo somlomo sikaSirolimus
Igama lomkhiqizo: Rapamune
Isebenza kanjani: Lo muthi usiza ukuvimbela ukwaliwa komzimba ngemuva kokuhlinzwa kokufakelwa kwezinso.
I-SingleCare iyakujabulela ukunikeza amakhasimende ethu okuningi imithi ejwayelekile ngentengo ehlisiwe. Yindlela eyodwa nje yokusiza ukongela imali kumuthi kadokotela.
