Ingabe i-beta blockers ingasiza ngokukhathazeka?

Imininingwane Yezidakamizwa

Ngo-Mashi ka-2020, nganginesikhathi sokubonana nodokotela wami oyinhloko wokunakekelwa. Ngamchazela ukuthi, yize ngangiseLexapro, i-serotonin reuptake inhibitor (SSRI) ekhethiwe, ngenxa yokukhathazeka nokudangala, ngangizizwa ngicindezelekile kwesinye isikhathi. Ngo-5 ntambama nsuku zonke, lapho izingane zisekhaya, zilambile, futhi zifuna ukunakwa, ngangizwa ukwethuka okukhulayo esifubeni sami. Ngangijuluka futhi ngezinye izikhathi ngibe nesiyezi. Kwesinye isikhathi ngangibabhekela izingane zami, noma ngangidinga ukuthatha ikhefu endaweni ethule, kude nabanye. Okokugcina kwe-Thanksgiving, bengilungiselela futhi ngipheka izinsuku ezimbili, kuphela ukuchitha ukudla okuningi egumbini lami lokulala. Ngitshele umhlinzeki wami wezokunakekelwa kwezempilo ukuthi ngifuna ukukwazi ukubhekana nezingcindezi ezingenakugwemeka empilweni yami ngaphandle kokuzwa sengathi ngicwila.

Udokotela wami wangitshela ukuthi ngangiphendula ngendiza futhi izimpawu zami zomzimba zazikhombisa ukuhlaselwa ukukhathazeka. Unginikeze i-propranolol, a i-beta blocker , ngokukhathazeka. Lolu hlobo lwemithi luvame ukusetshenziselwa ukulawula umfutho wegazi nezimo zenhliziyo. Ngangingenawo umlando wegazi eliphakeme noma izinkinga zenhliziyo, kodwa wangitshela ukuthi ukuthatha umthamo omncane wale Rx kuyindlela enhle yokubhekana nokukhathazeka kwesinye isikhathi. Njengomuntu ngokuvamile ozwela kahle emithini, bengingafuni ukuthatha okuthile okuqinile noma okungenzeka kube umlutha. Nginqume ukuthi ngizame.

Ngijabule kakhulu ngokuthi ngikwenzile! Lesi sifo sivale izikole (nakho konke okunye) ngesonto ngemuva kokuqokwa kwami. Ngazithola ngisekhaya ngo-24/7 nezingane zami, futhi kwaba sengathi ukuphela komhlaba kwakusondele ekhoneni. Ngangibonga kakhulu ngepropranolol ngokukhathazeka kulezo zinyanga zokuqala zobhadane futhi manje, ngisaphephile ekhaya cishe unyaka ngemuva kwalokho.

OKUSHIWO: Ukuhlaselwa kokukhathazeka kuqhathaniswa nokwethuka

Ingabe ama-beta blocker ayasebenza ekukhathazekeni?

Ama-beta blocker awadalelwanga injongo yokwehlisa ukukhathazeka.Ama-beta blocker ajwayele ukunikezwa off-ilebula ngokukhathazeka, kuchaza USpencer Kroll, MD , Ph.D. kwezokwelapha, iumqondisi weNortheast Lipid Association.[Ukusetshenziswa kwelebula] kusho ukuthi akuvunyelwe yi-U.S. U.S. ukwelashwa kokukhathazeka.

Noma zenziwe ngokungafani nemithi yokulwa nokukhathazeka, ama-beta blockers angasiza ekwakheni umuzwa wokuzola lapho uwathatha. Ama-beta blockers anganciphisa izinga lokushaya kwenhliziyo, udokotela wezifo zengqondo waseHouston UJared Heathman , MD, kuchaza. Lapho sikhathazekile, ukushaya kwenhliziyo yethu kuyakhuphuka. Lokhu kuphakama kunikeza impendulo yobuchopho ukuthi umzimba wethu wethukile ngokufanele. Lokhu kuqinisa ukukhathazeka. Uma uvimbela ikhono lokukhuphula izinga lokushaya kwenhliziyo yakho ngokushesha okukhulu, inhliziyo yakho inganikeza impendulo ebuchosheni bakho ukuthi ayethuki, ikakhulukazi hhayi njengoba bekulindelwe ngenye indlela. Uma inhliziyo nomzimba wethu kuzolile, kunikeza impendulo ethokomalisayo ebuchosheni. Lokhu kunciphisa ukukhathazeka.

USheldon Zablow, MD , udokotela wezifo zengqondo oqinisekiswe yibhodi, ubiza le nqubo ngokuthi iluphu engeyinhle yokuphendula. Ubeka ama-beta blocker ngokukhathazeka ngoba aphula lo mjikelezo ngokunciphisa amandla omzimba okuveza izimpawu zomzimba. Ukubhekana nokusabela komzimba ekucindezelekeni kusiza ubuchopho bomuntu okhathazekile ukuthi buzole futhi bulawuleke ngokwengeziwe.

Lokho kungenza umehluko omkhulu kwikhwalithi yempilo lapho ukukhathazeka kukuthinta nsuku zonke. Ezinye izimpawu zokukhathazeka zizizwa zinzima kakhulu, futhi zicasula, ukuthi abantu ababhekene nazo baye esibhedlela esiseduzane. Kunezimpawu eziningi eziletha iziguli kudokotela noma egumbini lezimo eziphuthumayo ezigcina zikhathazekile, kusho uDkt Kroll. Lezi zimpawu zomzimba zokukhathazeka zibandakanya:

• Inhliziyo ishaya ngamandla
• Ukujuluka
• Ukulunywa
• Ukuphuka kwesikhumba
• Umfutho wegazi ophakeme
• Umlomo owomile
• Kunzima ukugwinya
• Izinkinga zamathumbu njengokucasuka esiswini noma ubuhlungu

Njengoba kuvela, ukunciphisa ukukhathazeka ngemuva kokuthatha i-beta blocker empeleni kungumphumela ohlangothini lomuthi. Ngakho-ke, noma umfutho wegazi lami ungekho ebangeni elidinga imishanguzo lapho ngingakhathazeki, i-PCP yami ehlakaniphile yenza lokho uDkt Kroll athi kuvame ukuba lusizo njengodokotela, okuwukusebenzisa leyo miphumela emibi njengengxenye ukwelashwa okuqondene nesiguli ngasinye. Ngangikhathazekile ngokuthi i-benzodiazepine (efana neXanax) yokukhathazeka ingenza ngizizwe ngithambekele kakhulu ukunakekela izingane zami. Ngakho-ke, esikhundleni salokho i-PCP yami yahamba ne-beta blocker.

Ama-beta blocker ahlala isikhathi esingakanani ekukhathazekeni?

Ngokusemthethweni, i- ukuphila okungaphelele wepropranolol amahora amathathu kuya kwayisithupha, kepha ngokuya nge uzizwa kanjani, qhubeka uhlele amahora ambalwa wokukhululeka. Ama-beta blocker ajwayele ukunqunywa ngefomu lephilisi okufanele athathwe ngomlomo. Umuthi usebenza ngokushesha okukhulu, ufinyelela amazinga aphezulu ngokushesha okungangehora elilodwa. Uma isisesistimeni sakho, imiphumela yokwehlisa yedosi ephansi ye-beta blocker ihlala amahora ambalwa.

Umthamo ojwayelekile we-beta blocker uyahluka ngokuya ngezimpawu zakho, ukuxilongwa, nezinye izimo zezokwelapha. Ngokukhathazeka, kukodwa, abahlinzeki bezokunakekelwa kwezempilo bavame ukuqala i-propranolol ngomthamo ophansi, bakhule kancane uma kunesidingo. Kukhona futhi nenguqulo ekhishwe isikhathi eside yepropranolol, kepha ngokukhathazeka, imvamisa inguqulo enganwetshwanga iyasetshenziswa.

Ngabe ama-beta blocker akwenza uzizwe kanjani?

Ama-beta blockers angasiza abantu abahlangabezana nokukhathazeka ukuthi bazizwe bezolile futhi belawula imizwa yabo ngaphandle kokubenza bazizwe bengaphansi kwethonya. Inhloso yokwelashwa kokukhathazeka ukuthi ukwazi ukuphila impilo yakho ngaphandle kwezimpawu emi endleleni yakho. Ama-beta blockers angehlisa impendulo ye-adrenaline yomzimba kuma-stressors ajwayelekile, ukuze ukwazi ukugxila kwezinye izinto.

Ngokungafani nama-SSRI — alawula ukukhathazeka nokudangala isikhathi eside futhi athatha amasonto ambalwa ukuqala ukusebenza — ama-beta blockers ayasebenza ekusetshenzisweni kokuqala futhi angasetshenziswa ngezikhathi ezithile ngaphandle kwemiphumela emibi. Zinciphisa izimpawu zokukhathazeka zesikhashana, kepha azelaphi ukukhathazeka. Uma uhlangabezana nezimpawu zokukhathazeka ubusuku nemini, ungahle udinge umuthi ohlukile, noma ukusebenzisa i-beta blocker ukwengeza omunye umuthi.

Ama-beta blockers angaba ukwelashwa okusebenzayo kokwesaba esiteji ngaphambi kwemicimbi noma ukuzibandakanya kokukhuluma esidlangalaleni — kanye nokukhathazeka ngokulala. Ngokomlando, bavame ukunikezwa abantu 'ngokukhathazeka kokusebenza' ngaphambi kokukhuluma esidlangalaleni nokwenza, uDkt Kroll uthi. Vele uqiniseke ukuthi uyazama ekhaya kuqala ukubona ukuthi umuthi ukuthinta kanjani ngaphambi kokuwusebenzisela umcimbi ocindezelayo.Zingasebenza ekukhathazekeni komphakathi uma kuthathwe ngaphambi kwamaqembu noma izinsuku - inketho ephephile nganoma yisiphi isikhathi lapho kuvela ukukhathazeka.

UDkt. Zablow uthi i-beta blocker ingasetshenziswa esikhundleni noma ngezinsiza zokulala ukunciphisa ukukhathazeka ngaphambi kokulala. Uma ukukhathazeka ngosuku olwedlule noma ukukhathazeka ngosuku olulandelayo kukhuphula izinga lokushaya kwenhliziyo, kuvimbela ushintsho lwemvelo ekulaleni, le blocker ye-beta ivimbela lokho kuphazamiseka.

Imiphumela emibi ye-beta blockers

Ama-beta blocker awabonakali enezinkinga noma ukukhathazeka kubantu abango-COVID-19, kusho uDkt. Kroll. Uma ukhathazekile ngokuthi i-beta blocker ingahle ibe nomthelela engozini yakho ye-coronavirus, buza umhlinzeki wakho wezokunakekelwa kwempilo ngaphambi kokuqala umuthi. Kukhona amathuba eminye imicimbi emibi evela kulolu hlobo lomuthi.

Imiphumela emibi ejwayelekile

Njengayo yonke imithi, kukhona okungaba khona okuqhamuka uma udla imishanguzo :

• Isiyezi
• Ubumhlophe
• Ukukhathala
• Ukwehla kobulili
• Isicanucanu
• Ubuhlungu besisu
• Uhudo
• Ukuqunjelwa

Imiphumela emibi kakhulu

Imiphumela emibi engavamile, kodwa ngezinye izikhathi iyenzeka:

• Ukusangana
• Izandla noma izinyawo ezibandayo
• Ubuthakathaka bemisipha
• Amajaqamba emisipha
• Ukuphelelwa umoya
• Ukulahleka kwememori
• Ukugcinwa kwamanzi
• Ushukela wegazi uyashintsha
• Ukuqwasha namaphupho amabi
• Ukusabela okweqile
• Ukuhlanza
• Ukunyakaza
• Ukuzuza kwesisindo
• Ukuqhuma kwesikhumba
• Izinguquko Zemizwa

Funa usizo lwezokwelashwa olusheshayo uma ukhombisa izimpawu zokungezwani komzimba okubandakanya: ukuphefumula kanzima, ukuvunguza, ukuvuvukala kwezandla noma ubuso, kanye / noma ukuqubuka kwesikhumba.

Ngokungafani imishanguzo yendabuko yokukhathazeka , ama-beta blockers awalutheki. I-Propranolol nokunye okunjalo akubangeli ukuncika kwezidakamizwa (noma izimpawu zokuhoxa lapho uyeka ukuzithatha) futhi kuphephile ukuthatha ngezikhathi ezithile isikhathi eside.

IPropranolol ilungele ngezindlela eziningi ngoba ngokungafani ne-benzodiazepines evame ukusetshenziselwa ukwelapha ukukhathazeka, ingathathwa ngaphandle kokukhathazeka ngokushayela, isetshenziswe ngemithi yezinhlungu, noma isetshenziswe notshwala, kusho uDkt. Zablow. Ngikunikeze ngempumelelo ukunciphisa imithamo ye-benzodiazepines edingekayo, imishanguzo yokudambisa imishanguzo, nama-antipsychotic.

Ngidonseleke kulo mphumela omuhle wesidakamizwa njengomzali obevame ukuba khona ngisho naphakathi kwamabili. Ngingathatha i-propranolol futhi anginazo izingqinamba ezizizwa ngingenangqondo ngokwanele ukushayela noma ukuxhumana nezingane zami, into engingayisho ngeminye imithi efana ne-benzodiazepines, njenge-Xanax.

Ngoba i-beta blocker isebenza ngokushesha kodwa futhi ingakhubazi abasebenzisi ngezinga elibalulekile, uDkt. Zablow uthi kuyasiza kumuntu onenkinga yokukhathazeka ukuthi avele aphathe ephaketheni lakhe ithuba lokuthi kube nesiqephu sokukhathazeka esingalindelekile-ukwazi nje kukhona lapho kunganciphisa ukuvela kwezimpawu zokukhathazeka.

Ngigcina imithi ekamelweni lami ubusuku bonke lapho ngingakwazi ukwehlisa ingqondo yami ematasa. Ngiphinde ngigcine ibhodlela ekhishini lapho izinkathazo zasemini zingivimba ekubeni ngumuntu ongcono kakhulu kimi. Angizidingi nsuku zonke, kodwa ngiyajabula ukuthi ziyatholakala lapho ngizidinga khona.

Yikuphi ukuvimba kwe-beta okulungele ukukhathazeka?

Abahlinzeki bezokunakekelwa kwempilo ngokuvamile babeka i-propranolol noma i-atenolol yokwelashwa okungekho kwelebula kokukhathazeka.Buza umhlinzeki wakho wezokunakekelwa kwempilo ukuthi imuphi umuthi ongakulungela kangcono futhi uqiniseke ukuthi unikeza umlando ogcwele wezempilo.Nayi umehluko oyisisekelo phakathi kwalokhu okubili:

I-Propranolol vs. atenolol yokukhathazeka
I gama le-brand	Inderal LA , Inderal XL , InnoPran XL	I-Tenormin
Igama elijwayelekile	I-Propranolol	I-Atenolol
Umthamo ojwayelekile wokukhathazeka	Imithamo iyahluka ngokuya ngesimo futhi ingahle isuke ku-10 mg iye ku-80 mg. Ngokukhathazeka kukodwa, kuvame ukubekwa umthamo ophansi.	25-100 mg
Imiphumela emibi ejwayelekile	Ubumhlophe, isiyezi, izingqinamba zamathumbu	Izandla nezinyawo ezibandayo, ukukhathala, ubuthakathaka
Funda kabanzi	Funda kabanzi	Funda kabanzi
Ukonga kwe-SingleCare	Thola isigqebhezana	Thola isigqebhezana

Lapho izivimbeli ze-beta zingakulungele

Uma unexhala elingapheli nelingalawulwa, ungadinga ukwelashwa okuvamile ukwedlula i-beta blocker eyenzeka ngezikhathi ezithile — njengomuthi wansuku zonke. Abanye abantu, njengami, basebenzisa i-beta blocker ngaphezu kwe-SSRI. UDkt Kroll uthi,Ngokuvamile, ama-beta blocker abekezeleleka kahle, futhi ukuhlangana kwezidakamizwa okuyizimpawu akuvamile.

Ama-beta blockers kungenzeka angabi inketho ekufanele uma unezici ezilandelayo:

• Isifuba Somoya: Ama-beta blockers angaphazamisa i-asthma, kusho uDkt. Heathman. Zingadala nezinkinga uma unazo imigwaqo yomoya engasebenzi ngoba ama-beta receptors angandisa izinkinga zokuphefumula.
• Izimo zezempilo ezidinga imithi: Ama-beta blockers angaxhumana nenani elikhulu lemithi ejwayelekile ebekiwe, kusho uDkt Kroll. Lokhu kufaka phakathi imishanguzo ethile yokulwa nomfutho wegazi ophakeme kanye ne-antianginal, imishanguzo eqeda ukuhleleka, imishanguzo elwa nokuvuvukala, izidakamizwa ze-psychotropic, imishanguzo yokulwa nezilonda, i-anesthetics, ama-cholesterol okwehlisa amanxusa, i-warfarin, imishanguzo yesifo sikashukela, kanye neminye imithi yesifo sofuba. Tshela umhlinzeki wakho wezokunakekelwa kwempilo ngayo yonke imithi oyiphuzayo, ukuze aqinisekise ukuthi akukho kuhlangana kwezidakamizwa.
• Ubudala besilisa noma obudala: Ama-beta blocker angasebenza kakhulu ezigulini ezisencane ezine-hypertension kuneziguli ezindala futhi angasetshenziswa ukuphatha umfutho wegazi ophakeme kwabesifazane beminyaka yokuzala, kuchaza uDkt. Kroll. Lapha, ubhekise kuyo njengesidakamizwa somfutho wegazi ophakeme nenzuzo eyengeziwe yokukhululeka kokukhathazeka. Abavimbela i-Betaakufanele isetshenziselwe ukukhulelwa ngaphandle kokuthi inzuzo idlula ingozi. Ngakho-ke, khuluma nodokotela wakho uma ukhulelwe noma uhlela ukukhulelwa.

Asikho isidakamizwa esingenasici futhi akekho umuntu ofanayo. Kimina, nakwabanye abaningi abanjengami, i-beta blocker yayisindisa impilo ngokomzwelo ngesikhathi esinzima kakhulu emlandweni. Imiphumela emihle yokukwazi ukugcina umoya wami upholile ngenkathi ngisekhaya nezingane zami, ngesikhathi esasingakaze sibonakale, naphezu kokubhekana nezingcindezi zomuntu siqu, wawuyigugu. Ngibonga kakhulu ukuthi i-PCP yami icabange ukunginikeza i-beta blocker. Awukwazi ukulawula impilo futhi kwesinye isikhathi kungaba nengcindezi — noma ngabe ivela kumcimbi omkhulu womhlaba, noma iminutia nje yansuku zonke yomsebenzi nomndeni. Ama-beta blockers angasiza ukufundisa umzimba wakho ukuthi, noma ngabe impilo imnandi kakhulu, ungabhekana nayo, ubhekane nayo, futhi uchume.