Main >> Izidakamizwa Vs. Umngani >> I-Wellbutrin vs. Chantix: Umehluko, ukufana, nokuthi yikuphi okungcono kuwe

I-Wellbutrin vs. Chantix: Umehluko, ukufana, nokuthi yikuphi okungcono kuwe

Izidakamizwa Vs. Umngani

Siyakuhalalisela — usunqumile yeka ukubhema ! Wenza isinqumo esihle ngempilo yakho yonke. Ngokushesha, umfutho wegazi nokushaya kwenhliziyo yakho kuzokwehla. Kungakapheli usuku olulodwa, ingozi yokuhlaselwa yisifo senhliziyo izokwehla. Ezinye izinzuzo zifaka i-cholesterol ephansi, amathuba amancane omdlavuza wamaphaphu , namathambo aqinile namasosha omzimba.

Kwesinye isikhathi, kunzima ukuyeka ukubhema uwedwa, futhi udokotela wakho kungenzeka ukuthi ukhulume ngokusebenzisa umuthi kadokotela ukukusiza ungabhemi. I-Wellbutrin (i-bupropion hydrochloride) ne-Chantix (i-varenicline tartrate), eyenziwe yi-Pfizer, yizidakamizwa ezimbili ezidumile ezisetshenziselwa ukusiza iziguli ziyeke ukubhema, futhi zamukelwa yi-FDA ngokuyeka ukubhema. Yize zombili zisetshenziselwa inhloso efanayo, zinokuhlukahluka okuningi.

Uyini umehluko omkhulu phakathi kweWellbutrin neCantix?

I-Wellbutrin yimithi elwa nokudangala, ebekiwe off-ilebula ngokuyeka ukubhema. Akucaci ukuthi uWellbutrin usebenzela kanjani ukuyeka ukubhema, kepha siyazi ukuthi kuyasiza ukunciphisa izifiso futhi kunciphisa nezimpawu zokuhoxa. Itholakala kuthebhulethi ekhishwa ngokushesha (ejwayelekile) kanye nethebhulethi ekhishwa okuqhubekayo (i-SR) nethebhulethi ekhishwe isikhathi eside (XL). Ukwakheka kwe-SR ne-XL kokubili kuyatholakala nge-brand kanye ne-generic. I-SR inikezwa kabili ngosuku futhi i-XL ibekwa kanye ngosuku.

I-Chantix i-nicotinic agonist — inamathela kuma-nicotine receptors ebuchosheni, ukuze i-nicotine ingakwazi. Itholakala ngegama lomkhiqizo kwifomu yethebhulethi. Asikho isidakamizwa esiqukethe i-nicotine.

Umehluko omkhulu phakathi kwe-Wellbutrin vs. Chantix
	I-Wellbutrin	I-Chantix
Isigaba sezidakamizwa	I-Aminoketone antidepressant	Usizo lokuyeka ukubhema i-agonist agonist
Isimo somkhiqizo / ejwayelekile	Umkhiqizo nokujwayelekile	Umkhiqizo
Ngubani igama elijwayelekile?	I-Bupropion	I-Varenicline
Izidakamizwa zingena ngaziphi izinhlobo?	Ithebhulethi Ithebhulethi ye-SR (ukukhululwa okuqhubekayo, ukuphindwe kabili nsuku zonke) Ithebhulethi ye-XL (ukukhishwa okunwetshiwe, ukufakwa kanye ngosuku	Ithebhulethi
Uyini umthamo ojwayelekile?	Qala isonto elilodwa ngaphambi kosuku lokuyeka ukubhema: I-150 mg SR nsuku zonke izinsuku ezingama-3, bese i-150 mg SR kabili ngosuku	Qala isonto elilodwa ngaphambi kosuku lokuyeka ukubhema: 0.5 mg nsuku zonke izinsuku ezi-3, bese u-0.5 mg kabili ngosuku izinsuku ezingama-4, bese u-1 mg kabili nsuku zonke ngemuva kwalokho
Yelashwa isikhathi esingakanani?	Iyahlukahluka	Amaviki ayi-12, angaqhubeka amanye amasonto ayi-12
Ubani ovame ukusebenzisa umuthi?	Abantu abadala	Abantu abadala

Izimo eziphathwe yi-Wellbutrin vs. Chantix

I-Wellbutrin inqunyelwe ngaphandle kwelebula njengesizo ekwelashweni kokuyeka ukubhema. I-Wellbutrin ingahle inqunyelwe noma ngaphandle kwe-nicotine replacement therapy (NRT). Ukufaka esikhundleni se-nicotine kungasetshenziswa ngesimo se-nicotine patch noma i-lozenge, ngokwesibonelo, futhi kanye ne-Wellbutrin, izifiso zakho ze-nicotine kufanele zehle.

I-Wellbutrin (zonke izinhlobo) ikhonjiswa ngesifo sokucindezeleka okukhulu. I-Wellbutrin XL nayo ikhonjisiwe ngesifo sokuphazamiseka sonyaka. I-Wellbutrin inokusetshenziswa okuhlukahlukene kwelebula, okuningiliziwe eshadini elingezansi.

Kungenzeka futhi ukuthi uke wezwa Zyban , equkethe isithako esisebenzayo (i-bupropion) njenge-Wellbutrin. I-Zyban ikhonjisiwe ukuthi isetshenziselwe ukwelashwa ukuyeka ukubhema. I-Wellbutrin ivame ukusetshenziselwa ukuyeka ukubhema, yize kungakhonjisiwe ngokusemthethweni ngale njongo. Imininingwane ebekiwe uthi , I-Wellbutrin SR ayivunyelwe ukwelashwa kokuyeka ukubhema; kodwa-ke, iqukethe isithako esisebenzayo esifanayo nomuthi wokuyeka ukubhema uZyban. Noma kunjalo, odokotela bavame ukunquma uWellbutrin ukuthi ayeke ukubhema ngenhloso yokutholakala komshuwalense.

I-Chantix ikhonjiswe ukwelashwa kokuyeka ukubhema. I-Chantix akufanele ithathwe kanye ne-NRT ngoba ingadala ukwanda kwesicanucanu, ukuhlanza, ikhanda elibuhlungu, isiyezi, isisu esiphazamisayo nokukhathala.

Isimo	I-Wellbutrin	I-Chantix
Usizo ekwelashweni ukuyeka ukwelashwa	Ngaphandle kwelebula	Yebo
Isifo sokudangala esikhulu (ukukhululwa ngokushesha kwe-Wellbutrin, i-SR, i-XL)	Yebo	Akunjalo
Ukuphazamiseka kwesizini (i-Wellbutrin XL)	Yebo	Akunjalo
I-ADHD	Ngaphandle kwelebula	Akunjalo
Ukukhuluphala ngokweqile	Ngaphandle kwelebula	Akunjalo
Ukuphazamiseka kwe-bipolar	Ngaphandle kwelebula	Akunjalo
PTSD	Ngaphandle kwelebula	Akunjalo
Ukwesaba umphakathi	Ngaphandle kwelebula	Akunjalo
Ukungasebenzi ngokocansi	Ngaphandle kwelebula	Akunjalo

Ingabe i-Wellbutrin noma i-Chantix isebenza kangcono?

Ukuphepha nokusebenza kwe-bupropion kwafundwa kaningana izilingo , usebenzisa i-bupropion ngendlela yeZyban kanye nokwelulekwa. Esifundweni samasonto ayisikhombisa, i-bupropion ikhonjiswe ukuthi isebenza ngempumelelo kakhulu kune-placebo. Ezinyangeni eziyisithupha, iziguli zenze kangcono ekulondolozeni ukungazitholi ngemuva kokuphathwa nge-bupropion. Kwesinye isifundo, ukwelashwa nge-bupropion nakho kuphumelele kakhulu kune-placebo, kunciphisa isifiso sokubhema, nokunciphisa izimpawu zokuhoxa (njengokucasuka, intukuthelo nokukhathazeka).

Ekuvivinyweni kwemitholampilo, uChantix watholakala ukunciphisa isifiso sokubhema , ukunciphisa izimpawu zokuhoxa, nokusiza iziguli ukuba zigweme ukuzithiba. Izifundo ezimbili ziqhathanisa i-Chantix ne-bupropion ne-placebo amasonto ayi-12 kanti iziguli zilandelwe amasonto angama-40 ngemuva kokwelashwa. Kwesinye isifundo, iziguli ezingama-44% ezithatha i-Chantix ziyeke ukubhema phakathi namasonto 9 kuya ku-12, uma kuqhathaniswa neziguli ezingama-30% ezithatha i-bupropion ne-17% yeziguli ezithatha i-placebo. Olunye ucwaningo lubonise imiphumela efanayo.

Ucwaningo luthole ukuthi yomibili le mithi ibingcono kune-placebo, futhi iphethe ngokuthi iChantix ibisebenza kangcono kuneZyban.

Zombili lezi zidakamizwa zingasebenza kakhulu ekwelapheni ukuyeka ukubhema, kepha wonke umuntu uhlukile ngendlela abasabela ngayo emithini ethile. Umuthi osebenza kahle kakhulu kuwe unganqunywa udokotela wakho, ongabheka isimo (s) sakho sezokwelapha nomlando, kanye nanoma yimiphi eminye imishanguzo oyiphuzayo engasebenzisana neWellbutrin noma iChantix.

Ukuqhathaniswa kanye nezindleko ze-Wellbutrin vs. Chantix

I-Wellbutrin imbozwa umshwalense kanye ne-Medicare Part D, ngendlela ejwayelekile ye-bupropion. Ukucela umkhiqizo wegama lomkhiqizo kuzobiza kakhulu futhi kungahle kungambozwa. Ngaphandle komshuwalense, igama lomkhiqizo i-Wellbutrin SR libiza cishe ama- $ 541 ngokunikezwa kwenyanga eyodwa, kuyilapho okujwayelekile kubiza okungaphansi kwe- $ 15 ngekhuphoni le-SingleCare.

I-Chantix imbozwa umshwalense kanye ne-Medicare Part D. Ngaphandle komshwalense, iphakethe lenyanga yokuqala le-Chantix libiza phakathi kuka- $ 500- $ 600, futhi iphakethe lezinyanga eziqhubekayo libiza ngaphansi kuka- $ 450 ngokusebenzisa ikhadi lesaphulelo le-SingleCare.

	I-Wellbutrin	I-Chantix
Ngokuvamile embozwe umshwalense?	Yebo (okujwayelekile; umkhiqizo ungaba ne-copay ephakeme noma ufune ukugunyazwa kwangaphambili)	Yebo
Imbozwe ngokujwayelekile yi-Medicare Part D?	Yebo (okujwayelekile)	Yebo
Umthamo ojwayelekile	# 60, 150 mg amaphilisi e-SR	Iphakethe lenyanga eli-1 lokuqala noma Iphakethe lenyanga eli-1 eliqhubekayo
Inkokhelo ejwayelekile yeMedicare Part D	$ 0- $ 47	$ 25- $ 578
Izindleko ze-SingleCare	$ 15- $ 40	$ 450 +

Imiphumela emibi ejwayelekile yeWellbutrin neChantix

Imiphumela emibi kakhulu ye-Wellbutrin yikhanda, umlomo owomile, isicanucanu, ukuqwasha, ukuqunjelwa, nesiyezi. Imiphumela emibi kakhulu ye-Chantix yikhanda, isicanucanu, ukuqwasha, namaphupho angajwayelekile. Uzothola umhlahlandlela wemithi, onolwazi ngemiphumela engemihle, ngomuthi omusha noma wokugcwalisa kabusha we-Wellbutrin noma weChantix. Eminye imiphumela emibi kungenzeka. Xhumana nomhlinzeki wakho wezokunakekelwa kwempilo ukuthola uhlu olugcwele lwemiphumela emibi.

	I-Wellbutrin	I-Chantix
Imiphumela emibi	Kusebenza?	Imvamisa	Kusebenza?	Imvamisa
Ubuhlungu bekhanda	Yebo	26%	Yebo	15-19% *
Umlomo owomile	Yebo	17%	Yebo	4-6%
Isicanucanu	Yebo	13%	Yebo	16-30%
Ukuqunjelwa	Yebo	10%	Yebo	5-8%
Ukuphelelwa isifiso sokudla	Yebo	5%	Yebo	1-2%
Ukuqwasha / inkinga yokulala	Yebo	ishumi nanye%	Yebo	18-19%
Amaphupho angajwayelekile / acacile	Akunjalo	Ayikho	Yebo	9-13%
Isiyezi	Yebo	7%	Yebo	Kubikwe njengokuvamile
Ukuthuthumela	Yebo	6%	Yebo	Kubikwe njengokuvamile
Ukukhathazeka	Yebo	5%	Yebo	% akubikiwe
Ukujuluka	Yebo	6%	Akunjalo	Ayikho
I-Rash	Yebo	5%	Yebo	1-3%
Tinnitus	Yebo	6%	Yebo	Kubikwe njengokuvamile

* Kuyahluka ngokuya ngomthamoSource: DailyMed ( I-Wellbutrin ), IDailyMed ( I-Chantix )

Ukusebenzisana kwezidakamizwa kwe-Wellbutrin vs. Chantix

Ngenkathi i-Wellbutrin ingasetshenziswa ngokubambisana ne-NRT, i-Chantix akufanele isetshenziswe ne-nicotine ngenxa yengozi yemiphumela emibi eyengeziwe. Utshwala akufanele busetshenziswe ne-Wellbutrin noma i-Chantix.

I-Wellbutrin inokunye ukuxhumana okuningi kwezidakamizwa. I-Wellbutrin akufanele isetshenziswe ngokuhlanganyela nama-MAO inhibitors — ukusetshenziswa kwayo kufanele kwehlukaniswe okungenani izinsuku eziyi-14. I-Wellbutrin nayo ingasebenzisana nama-anticonvulsants ahlukahlukene, ama-anti-depressants, ama-antipsychotic, ama-benzodiazepines, ama-opioid, noma ama-beta blocker. Okunye ukuxhumana kwezidakamizwa kungenzeka. Xhumana nomhlinzeki wakho wezokunakekelwa kwempilo ukuthola uhlu oluphelele lokuhlangana kwezidakamizwa.

Izidakamizwa	Isigaba Sezidakamizwa	I-Wellbutrin	I-Chantix
I-Nicotine	Ukwelashwa kokufaka esikhundleni seNicotine	Akunjalo	Yebo
Utshwala	Utshwala	Yebo	Yebo
ICarbamazepine I-Divalproex sodium UGabapentin I-Lamotrigine I-Oxcarbazepine I-Phenobarbital Phenytoin I-Topiramate	Ama-anticonvulsants	Yebo	Akunjalo
Clonazepam I-Diazepam I-Lorazepam	I-Benzodiazepines	Yebo	Akunjalo
Amitriptyline I-Citalopram I-Desipramine I-Desvenlafaxine I-Duloxetine I-Escitalopram	Izidambisi	Yebo	Akunjalo
I-Phenelzine I-Rasagiline USelegiline I-Tranylcypromine	Ama-inhibitor e-MAO	Yebo	Akunjalo
ICodeine Fentanyl I-Hydrocodone I-Hydromorphone I-Methadone I-Morphine I-Tramadol	Ama-opioid	Yebo	Akunjalo
I-Haloperidol I-Risperidone I-Thioridazine	Ama-antipsychotic	Yebo	Akunjalo
I-Atenolol I-Metoprolol I-Propranolol	Abavimbela i-Beta	Yebo	Akunjalo
I-Clopidogrel	I-Antiplatelet	Yebo	Akunjalo
I-Digoxin	I-glycoside yenhliziyo	Yebo	Akunjalo

Izexwayiso zikaWellbutrin noChantix

Izexwayiso zika-Wellbutrin:

I-Wellbutrin iza nesixwayiso sebhokisi elimnyama (isexwayiso esiqine kakhulu njengoba kudingwa yi-FDA) ngokuzibulala. Ama-anti-depressants, njenge-bupropion, angakhuphula ubungozi bemicabango yokuzibulala nokuziphatha ezigulini ezineminyaka engama-24 nangaphansi. Iziguli nabanakekeli bazo kufanele bazi noma yiziphi izinguquko ezimeni zomoya, ukubona izinto ezingekho, ukucabanga okuphambeneyo, ukukhohlisa, umbono wokubulala, ulaka, ubutha, ukucasulwa, ukukhathazeka, kanye / noma ukwethuka. Noma yisiphi isiguli esithatha i-Wellbutrin, noma ngabe sineminyaka emingaki, kufanele siqashwe ngeso elibukhali ngalezi zimpawu.
Kukhona ubungozi be-mania noma i-psychosis-ingozi iphakeme ezigulini ezine-bipolar disorder.
I-Wellbutrin ingadala ukuquleka. Ingozi ihlobene nomthamo-umthamo kufanele ukhuphuke kancane futhi ungadluli i-300 mg ngosuku. Ezinye izimo zezokwelapha nazo zingakhuphula ubungozi bokuquleka. Xhumana nochwepheshe wezokunakekelwa kwempilo ukuthola eminye imininingwane.
Ngoba iWellbutrin ingadala umfutho wegazi ophakeme, umfutho wegazi kufanele ubhekwe ngenkathi uthatha iWellbutrin.
Iziguli ezithile zingaba sengozini ye-glaucoma. Xhumana nodokotela wamehlo ukuthola eminye imininingwane.
I-Stevens-Johnson syndrome kungenzeka. Lokhu kuyingozi, engabeka impilo engozini, ukusabela kwesikhumba. Xhumana nomhlinzeki wakho wezokunakekelwa kwempilo ngokushesha uma uba nokuqubuka kwesikhumba.

I-Wellbutrin imvamisa ayisetshenziswa ekukhulelweni, futhi kufanele isetshenziswe kuphela uma inzuzo engaba khona ibeka engcupheni engaba khona enganeni. Ababhemayo abakhulelwe kufanele bakhuthazwe ukuba bayeke ukubhema ngokusebenzisa izindlela zokuziphatha ngaphambi kokusebenzisa iWellbutrin. Xhumana ne-OB-GYN yakho ukuthola izeluleko.

Izexwayiso ze-chantix:

UChantix unesixwayiso esibhokisi semicimbi emibi ye-neuropsychiatric. Ukudana, ukucabanga ukuzibulala, ukuzama ukuzibulala, nokuzibulala kuqediwe kubikwe ezigulini ezithatha iChantix. Kufanele uyeke ukuthatha i-Chantix bese uthinta umhlinzeki wakho wezokunakekelwa kwempilo ngokushesha uma uhlakulela ukucasuka, ubutha, imizwa edangele, noma ushintsho ekuziphatheni noma ekucabangeni okungajwayelekile, noma uma uhlangabezana nemicabango yokuzibulala. Iziguli kuChantix kufanele zihlolwe kakhulu.
Kukhona ingozi ye-hypersensitivity noma i-angioedema, okuvuvukala ebusweni, emlonyeni, emaphethelweni nasentanyeni. Misa i-Chantix futhi ufune usizo lwezimo eziphuthumayo uma kwenzeka lezi zimpawu.
Njengo-Wellbutrin, i-Stevens-Johnson syndrome ingaxhumana noMhlinzeki wakho wezokunakekelwa kwezempilo ngokushesha uma uba nokuqubuka kwesikhumba.
Kungahle kube nethuba elanda kancane lezehlakalo zenhliziyo-yazisa umhlinzeki wakho wezokunakekelwa kwempilo ngezimpawu ezintsha noma eziya ziba zimbi zesifo senhliziyo.
Sebenzisa ukushayela ngokuqapha uze wazi ukuthi i-Chantix ikuthinta kanjani. Ukulimala ngengozi kwenzeke ngenxa yokulala noma isiyezi esivela kuChantix.

I-Chantix ingadala ingozi embungwini uma isetshenziswe ngesikhathi sokukhulelwa, futhi ngokuvamile akufanele isetshenziswe. Ezifundweni zezilwane, uChantix ubangele ukwehla kwesisindo somntwana kanye nokwehla kokuzala enzalweni. Njengaku-Wellbutrin, ababhemayo abakhulelwe kufanele bakhuthazwe ukuthi bayeke ukubhema ngokusebenzisa izindlela zokuziphatha.

Ngo-2016, i- Kubikwe i-FDA ukuthi ubungozi bemiphumela emibi yezempilo yengqondo evela kuZyban noChantix bungaba ngaphansi kunalokho obekucatshangwa ngaphambili nokuthi izinzuzo zokuyeka ukubhema zidlula izingozi zokusebenzisa le mithi. Noma lo mbiko ubhekise kuZyban, iWellbutrin iqukethe isithako esisebenzayo esifanayo, i-bupropion. Akunandaba, imininingwane yezidakamizwa isenezixwayiso ezifanayo futhi iziguli kufanele ziqashwe ngeso lokhozi ngenkathi zikuWellbutrin noma eChantix.

Imibuzo ebuzwa njalo nge-Wellbutrin vs. Chantix

Kuyini iWellbutrin?

I-Wellbutrin iyimithi kadokotela yokulwa nokucindezelwa esetshenziswa ngaphandle kwelebula (nge-nicotine noma esikhundleni se-nicotine therapy) ukusiza iziguli ziyeke ukubhema.

Kuyini i-Chantix?

I-Chantix ngumuthi kadokotela osetshenziselwa ukusiza iziguli ziyeke ukubhema.

Ingabe i-Wellbutrin ne-Chantix ziyefana?

Cha, azifani. I-Wellbutrin iyi-antidepressant esiza ukunciphisa izifiso ze-nicotine, kuyilapho i-Chantix isebenza ikakhulukazi kuma-nicotine receptors. Banokunye umehluko futhi, okuchazwe ngenhla.

Ngabe iWellbutrin noma iCantix ingcono?

Yomibili le mithi iyasebenza ekusizeni iziguli ziyeke ukubhema. Uma ufuna ukusebenzisa i-nicotine therapy esikhundleni semithi kadokotela, i-Wellbutrin kungaba yindlela engcono ngoba ingathathwa kanye ne-NRT, futhi i-Chantix akufanele ithathwe kanye ne-NRT. Buza udokotela wakho ukuthi i-Wellbutrin noma i-Chantix ingaba ngcono kuwe.

Ngingayisebenzisa i-Wellbutrin noma i-Chantix ngenkathi ngikhulelwe?

Cha. Uma ukhulelwe, thintana nomhlinzeki wakho wezokunakekelwa kwempilo. I-Wellbutrin ne-Chantix akusetshenziswa kakhulu kwabesifazane abakhulelwe. Uma usuvele uthatha i-Wellbutrin noma i-Chantix futhi uthola ukuthi ukhulelwe, xhumana ne-OB-GYN yakho ngokushesha ukuze uthole isiqondiso.

Ngingayisebenzisa i-Wellbutrin noma i-Chantix ngotshwala?

Cha. UWellbutrin onotshwala angakhuphula ingozi yokuquleka.

Yini engcono ukuyeka ukubhema, iCantix noma iWellbutrin?

Zombili lezi zidakamizwa zisizile iziguli ukuthi ziyeke ukubhema, kepha kungcono ukukhuluma nodokotela wakho futhi nixoxe ngokuthi iChantix noma i-Wellbutrin kungaba yini umuthi ofanele kuwe, kucatshangelwa isimo (s) sakho sempilo, umlando, neminye imithi oyiphuzayo.

Kuthatha isikhathi esingakanani ukuqala ukusebenza?

Kungathatha amasonto ambalwa ukuthi i-Chantix iqale ukusebenza. Udokotela wakho angakutshela ukuthi uthathe i-Chantix cishe amasonto ayi-12. Uzoqala ngephakethe lezinyanga zokuqala, bese uqhubeka nephakethe lezinyanga eziqhubekayo. Ngemuva kwamasonto ayi-12, udokotela wakho uzonquma ukuthi udinga ukuthatha i-Chantix ngamanye amasonto ayi-12.

Uqala kanjani ukusebenza ngokushesha uWellbutrin?

Kungathatha amasonto ambalwa ukuthatha i-Wellbutrin (nge-NRT noma ngaphandle kwayo) uze ubone umehluko. Xhumana nodokotela wakho ukuthola ukuthi kufanele uthathe i-Wellbutrin isikhathi esingakanani.