Main >> Imininingwane Yezidakamizwa >> Yini iVivvanse futhi isetshenziselwani?

Yini iVivvanse futhi isetshenziselwani?

Imininingwane Yezidakamizwa

IVyvanse ngumuthi ovuselelayo ongaphatha ukunakekelwa kokushoda kwengqondo (ADHD) kanye nenkinga yokudla ngokweqile (BED). Kuyasiza ukunciphisa izimpawu ze-ADHD njengokunganaki, ukukhohlwa, kanye nokungasebenzi kahle. Kungasiza futhi ukulawula ukuthanda ukudla kubantu abanenkinga yokudla ngokweqile. Ngezansi, sizobheka ukuthi yini i-Vyvanse nokuthi iqhathaniswa kanjani neminye imithi.

OKUSHIWO: Thola amakhuphoni kaVyvanse | Funda kabanzi mayelana noVyvanse

Yini iVyvanse, futhi isetshenziselwani?

IVyvanse (lisdexamfetamine dimesylate) umuthi kadokotela owenziwa yiShire Pharmaceuticals. Ayikho inguqulo ejwayelekile yalo muthi.

Lo muthi okhuthazayo uqukethe i-lisdexamfetamine, i-prodrug ye-amphetamine. Kuyisidakamizwa esilawulwayo sesheduli II esinamandla aphakeme okusetshenziswa kabi, ukuhlukunyezwa, kanye nokuncika.

I-Vyvanse ye-ADHD

IVivvanse isetshenziselwa ifayili le- ukwelashwa kwe-ADHD ngokwenza ngcono ukugxila nokunciphisa ukungaziphathi nokuziphatha okungaxakile. Kuvunyelwe iziguli ezine-ADHD ezineminyaka engu-6 noma ngaphezulu. Kusukela ngo-2016, Izingane ezingama-62% ezine-ADHD abaneminyaka engu-2 kuya kwengu-17 ubudala bebephuza imishanguzo ye-ADHD. Izifundo zomtholampilo ezinganeni ezine-ADHD zithole ukuthi uVyvanse uthuthuke kakhulu ekuziphatheni, ngokuya nge-ADHD Rating Scale (ADHD-RS), uma kuqhathaniswa ne-placebo.

Vyvanse ngokudla ngokweqile

Ukuphazamiseka kokudla ngokweqile yiyona ukuphazamiseka kokudla okuvame kakhulu eU.S. , futhi kubonakala ngokudla inani elikhulu lokudla ngezikhathi ezincane. Abantu abanenkinga yokudla ngokweqile bavame ukuzizwa bengenakho ukulawula phezu kwesifiso sabo.

Izifundo kukhombisile ukuthi iVivvanse inciphisa inani lezinsuku zokudla ngokweqile ngesonto uma kuqhathaniswa ne-placebo. Kuphethe ngokuthi i-50 kuya kuma-70 mg ngosuku iyazuzisa kulabo abanenkinga yokudla ngokweqile kuya kokulingene.

Ngaphezu kwalokho, uVyvanse yi kuqala futhi kuvunyelwe kuphela imishanguzo eyenziwe yi-United States Food and Drug Administration (FDA) ukusiza ukwelapha ukuphazamiseka kokudla ngokweqile. Kodwa-ke, ochwepheshe abayincomi iVyvanse yokwehlisa isisindo noma yokwelapha ukukhuluphala.

Usebenza kanjani uVyvanse?

IVyvanse yisidakamizwa, okusho ukuthi sisebenza kuphela lapho senziwe umzimba, noma sicutshungulwa, emzimbeni. I-lisdexamfetamine iguqula ibe yi-dextroamphetamine lapho ifinyelela kupheshana lesisu (GI). I-Dextroamphetamine isebenza ohlelweni lwezinzwa oluphakathi (CNS) futhi yandisa umsebenzi we-dopamine ne-norepinephrine ebuchosheni.

I-Dopamine ne-norepinephrine ngama-neurotransmitters angathinta ukunaka komuntu, imizwa yakhe, kanye nogqozi. Abantu abane-ADHD bangaba namazinga aphansi e-dopamine nomsebenzi we-norepinephrine, obenza ukuthi babhekane nezinkinga ngokunakwa, ukungasebenzi kahle, noma ukungafisi.

IVyvanse ivimba ukuphinda kuthathwe kabusha kwe-dopamine ne-norepinephrine neurotransmitters, engasiza ekuthuthukiseni isimilo nokuziphatha okungaphumeleli kulabo abane-ADHD.

Ungayithatha kanjani i-Vyvanse

UVyvanse uvame ukunqunywa ukuthi athathwe kanye ngosuku, ekuseni — nokudla noma ngaphandle kokudla. Imithamo isukela ku-30 kuye ku-70 mg. I-Vyvanse iyatholakala njenge-capsule yomlomo evame ukuqala ukusebenza kungakapheli ihora elilodwa ngemuva kokuyithatha. Ifinyelela esiqongweni sayo cishe emahoreni amane, bese imiphumela iguga ngemuva kwamahora afika kwayi-14. UVyvanse uza ne-capsule ekhishwe ukubambezeleka engasiza ekuthuthukiseni ukunamathela emithini futhi kunciphise amandla imiphumela ebuyile ekupheleni kosuku.

Imvamisa, isilinganiso seVivvanse sesiguli esisha sizoqala ku-30 mg. Umthamo ophakeme akufanele uthathwe ngaphandle kwemvume yomhlinzeki ngoba kubalulekile ukuhlola ukuthi lowo muntu uphendula kanjani emithini kuqala.

IVyvanse iyatholakala njenge-capsule yomlomo nethebhulethi ehlafunwayo. Ama-capsules omlomo eza ngamandla ka-10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, no-70 mg. Amathebulethi angahlafunwa angena ngamandla ka-10 mg, 20 mg, 30 mg, 40 mg, 50 mg, no-60 mg.

I-capsule yomlomo ingalawulwa ngengilazi yamanzi noma ijusi, noma okuqukethwe ku-capsule kungaxubaniswa nokudla, njenge-yogurt. Vele uvule i-capsule bese uxuba i-powder ekudleni kwakho. Khumbula ukuthi ukudla okunothe uvithamini C njengejusi lewolintshi kunganciphisa amandla omzimba okuthola iVivvanse, okunganciphisa ukusebenza komuthi.

Ukweqisa ngokweqile, imithamo ephuthelwe, nokuhoxa

Ungadlula ngokweqile kuVyvanse uma uyithatha ngokungafanele. Izimpawu zokudlula ngokweqile kweVyvanse kufaka phakathi ukusangana, ukwethuka, ukundindizela, ukungahlaliseki, ukudideka, ukuphefumula okusheshayo, nobuhlungu bemisipha.

Uma uphuthelwa umthamo weVyvanse, wuthathe ngokushesha lapho ukhumbula. Kodwa-ke, uma sekuhlwile vele, kungcono ukweqa umthamo walolo suku. Ungalokothi uthathe umthamo owengeziwe ukwenza isilinganiso esilahlekile.

Ungakuthola ukuhoxa uma uyeka ukuthatha uVyvanse ngokungazelelwe. Izimpawu zokuhoxa zingabandakanya ukuzamazama, ukujuluka, ukucasuka, ukukhathala nokudangala. Njengoba lesi sidakamizwa siphela usuku lonke, abanye abantu bangathola ukuphahlazeka. Ukuphahlazeka kukaVyvanse kuyinto ejwayelekile ikakhulukazi lapho uqala umuthi okokuqala, futhi izimpawu zingafana nalezo zokuhoxa, njengokucasuka nokukhathala. Xhumana nomhlinzeki wakho wezokunakekelwa kwezempilo uma uhlangabezana nalezi zimpawu njalo.

Bheka umhlahlandlela wakho wemithi weVyvanse ukuthola eminye imininingwane yokuthi ungayithatha kanjani i-Vyvanse.

Isitoreji

Gcina iVyvanse ekamelweni lokushisa eliphakathi kwama-68 nama-77 degrees F. Yigcine ikude nokukhanya ukuze ikugweme ukushisa.

Kungcono ukubeka iVivvanse egumbini elikhiyiwe, ikakhulukazi uma uhlala nezingane.

Uma umhlinzeki wakho wezokunakekelwa kwezempilo ekuyala ukuba uyeke ukuthatha iVivvanse ungakaqedi incwadi yakho kadokotela, ungayilahli kudoti. Ingalimaza izilwane nabantu abathola iVyvanse. Esikhundleni salokho, funa uhlelo lokubuyisela emuva ekhemisi langakini. Funda ngokuthi ungakwenza kanjani lahla imithi kahle ukuthola eminye imininingwane.

Imininingwane yezokuphepha yakwaVyvanse

Imikhawulo

Akufanele uthathe iVyvanse uma uyi:

Ungaphansi kweminyaka engu-6 ubudala
Ukuzwela noma ukungezwani neminye imithi evuselelayo
Ukuthatha umuthi we-monoamine oxidase inhibitor (MAOI) noma uthathe i-MAOI ezinsukwini eziyi-14 ezedlule

Uhlu olwamukelwe yi-FDA lwama-MAOI lubandakanya iMarplan (isocarboxazid), iNardil (phenelzine), i-Emsam (selegiline), ne-Parnate (tranylcypromine). Ukuthatha ama-MAOIs ngeVyvanse kungakhuphula ubungozi be- isifo se-serotonin .

Khuluma nodokotela wakho uma ngabe uphendulile kuVyvanse noma eminye imishanguzo ye-ADHD esikhathini esedlule.

Izexwayiso

IVyvanse ingakhuphula izinga lokushaya kwenhliziyo yakho nomfutho wegazi. Ngakho-ke, labo abanezinkinga zenhliziyo noma ukukhubazeka kwenhliziyo kufanele bakhulume nomhlinzeki wabo wezempilo ngaphambi kokuthatha uVyvanse. Lo muthi kubikwe ukuthi udale ukufa okungazelelwe ezigulini ezinezimo zenhliziyo.

Tshela umhlinzeki wakho wezempilo uma ukhulelwe noma uhlela ukukhulelwa. Ayikho imininingwane eqinile yokuthi uVyvanse uthinta kanjani imibungu noma izingane ezingakazalwa. Funa izeluleko zezokwelapha uma udinga imithi ye-ADHD ngenkathi ukhulelwe noma uncelisa.

Izinto ezilawulwa nguhulumeni njenge-Vyvanse zisengozini enkulu yokuthembela ngoba umthamo omkhulu ungenza abanye abasebenzisi bazizwe bejabule. Kodwa-ke, ukusetshenziswa kabi kukaVyvanse kungaba nemiphumela emibi futhi ibulale impilo.

Okuqhamuka uma udla imishanguzo

Imiphumela emibi yeVyvanse yokwelapha i-ADHD nokuzitika ngokudla ngokweqile ifaka:

Ukukhathazeka
Ukwehla kwesifiso sokudla
Umlomo owomile
Inkinga yokulala
Ukuthukuthela

Eminye imiphumela emibi ehlotshaniswa noVyvanse ku-ADHD ifaka:

Ubuhlungu besisu phezulu
Isiyezi
Isicanucanu
Ukwehla kwesisindo
Uhudo

Abantu abanenkinga yokudla ngokweqile abathatha iVivvanse nabo bangathola:

Ukuqunjelwa
Ukunyuka kwenhliziyo

I-Vyvanse ingahle ibe nethuba elincane lokudala inkungu yobuchopho kuneminye imithi ye-ADHD, futhi, uma ifomu lokubambezeleka lokukhipha i-capsule, i-Vyvanse ingathuthukisa ngempumelelo ukugxila usuku lonke. Imiphumela emibi eqhubekayo noma emibi ingadinga isilinganiso esihlukile noma ushintsho emithini.

Ukusebenzisana

Kuningi ukuxhumana kwezidakamizwa noVyvanse . Okunye kokuxhumana okuyingozi kakhulu kweVyvanse kufaka:

Ama-MAOI, afana ne-tranylcypromine, isocarboxazid, ne-selegiline
Amanye ama-anti-depressants, afana ne-SSRIs, ama-SNRIs, kanye ne-tricyclic antidepressants
Ama-CYP2D6 inhibitors, njenge-paroxetine, i-ritonavir, ne-quinidine
Ama-alkalinizing agents, njenge-acetazolamide
Ama-ejenti enza amandla, njenge-ammonium chloride

I-Vyvanse, njengeminye imishanguzo ye-ADHD, ivame ukunconywa ukuthi igwenywe ngotshwala . Ukuhlanganisa uVyvanse notshwala kungakhuphula ubungozi bemiphumela emibi. IVyvanse iyashukumisa ngenkathi utshwala buyisidina. Ukuxuba lokhu kokubili kungaholela nasekuphuzeni ngokweqile kotshwala noma ekweqiseni kwiVyvanse.

Ezinye izindlela zikaVyvanse

Ziyini izinzuzo nezinkinga zikaVyvanse ngokuqhathaniswa neminye imithi ye-ADHD? Kuya ngezici ezahlukahlukene njengezindleko nemiphumela engemihle. Ezinye izindlela ezingaba khona ze-Vyvanse ze-ADHD zifaka:

URitalin (i-methylphenidate): URitalin uyisikhuthazi esisetshenziselwa ukwelapha i-ADHD ne-narcolepsy, kepha hhayi ukuzitika ngokudla.
Ikhonsathi (i-methylphenidate): IConcerta ifomu elikhishwe isikhathi eside le-methylphenidate, isithako esifanayo eRitalin.
Adderall (i-amphetamine / dextroamphetamine): I-Adderall ayisona isidakamizwa, ngokungafani neVivvanse, engaveza imiphumela ehlukile kwabanye abantu. I-Adderall XR inguqulo ekhishwe isikhathi eside ye-Adderall.
I-Focalin (dexmethylphenidate): I-Focalin (i-dexmethylphenidate) iyisikhuthazi esisebenza esifushane esifana ne-Adderall. Kepha i-methylphenidate ingasebenza kangcono kunama-amphetamine afana ne-Adderall ezinganeni.

Ngabe uVyvanse ungcono kune-Adderall?
	UVyvanse	Adderall
Izithako ezisebenzayo	I-Lisdexamfetamine dimesylate	I-Dextroamphetamine amphetamine
Isimo somkhiqizo / ejwayelekile	Igama lomkhiqizo kuphela	I-Brand ne-generic iyatholakala
Isigaba	I-CNS Ishukumisayo	I-CNS Ishukumisayo
Umthamo ojwayelekile nobude besikhathi	Okwe-ADHD (iminyaka engu-6 + ubudala): 30 mg kuya ku-70 mg kanye ngosuku ekuseni. Ngokuphazamiseka kokudla ngokweqile: 50 mg kuya ku-70 mg njalo ekuseni. Umthamo owodwa weVivvanse ungahlala amahora angu-14.	Ye-ADHD (iminyaka engu-3-5): 2.5 kuya ku-40 mg nsuku zonke. Ungathatha imithamo engu-1-3 ngosuku. Okwe-ADHD (iminyaka engu-6 + ubudala): 5 kuya ku-40 mg nsuku zonke. Ungathatha imithamo engu-1-3 ngosuku. Umthamo we-Adderall ungahlala amahora amane. Kodwa-ke, i-Adderall XR ingahlala amahora angu-8-12.
Imiphumela emibi ejwayelekile *	Ukukhathazeka Umlomo owomile Ukuqwasha Ukwehla kwesifiso sokudla Ukwehla kwesisindo	Ukuphelelwa isifiso sokudla Ukwehla kwesisindo Ukuqwasha Ubuhlungu besisu Ukwesaba Isicanucanu Ukushintsha kwemizwelo

* Imiphumela emibi iyehluka ngomthamo, ubudala, nenkomba.

IVyvanse iza njengephilisi lomlomo elibambezelekile, kanti i-Adderall iyithebhulethi ekhishwa ngokushesha. Kodwa-ke, i-Adderall XR ukwakhiwa kokukhishwa okwandisiwe kwe-Adderall. Abanye abantu bayazuza emithini ekhishwa ngokushesha uma ukukhishwa okweluliwe kuthatha isikhathi eside kakhulu ukuthi kusebenze. Imiphumela nokuncamelayo kungahluka.

I-Adderall itholakala ngemithamo emincane kulabo abaphakathi kweminyaka emi-3 kuya kwengu-5 ubudala. Ngokuphambene, iVivvanse ingeyalabo kuphela abaneminyaka engu-6 nangaphezulu.

Akuphephile ukuthatha iVivvanse ne-Adderall ngaphandle kwemithi kadokotela ovela kochwepheshe bezokunakekelwa kwempilo. IVyvanse ne-Adderall akufanele zithathwe ndawonye ngoba ziqukethe izithako ezinemiphumela efanayo. Ukuthatha le mithi ndawonye kungakhuphula nobungozi bemiphumela emibi.

Ekugcineni, omunye umuntu angakhetha uVyvanse kuno-Adderall kuye ngokuthi basabela kanjani emithini kanye nemiphumela engemihle abangahlangabezana nayo. Xhumana nomhlinzeki wezokunakekelwa kwezempilo ukuze unqume umuthi ongcono kakhulu we-ADHD wesimo sakho.

Ngezansi — khuluma nomhlinzeki wezokunakekelwa kwempilo ukuze ufunde kabanzi mayelana nokuthi i-Adderall noma i-Vyvanse ikufanele yini.